PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11927498-0	2002	CYP2A6 activity determined by caffeine phenotyping: association with colorectal cancer risk.	Caffeine	30-38	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	0-6	
11927498-2	2002	CYP2A6 phenotype was determined using caffeine as a probe drug in individuals participating in a case-control study of colorectal cancer (127 cases and 333 controls matched on age, gender, race, and geographic region).	Caffeine	38-46	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	0-6	
11927498-3	2002	Conversion of the caffeine metabolite 1,7-dimethylxanthine (17X) to 1,7-dimethyl uric acid (17U) is catalyzed primarily by CYP2A6, and this activity can be assayed by comparison of urinary molar ratios of metabolites.	Caffeine	18-26	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	123-129	
11927498-10	2002	We found a strong relationship between CYP2A6 activity, measured by urinary caffeine metabolite ratio, and colorectal cancer risk.	Caffeine	76-84	cytochrome P450 family 2 subfamily A member 6	Homo sapiens	39-45