PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11861798-3 2002 Time- and concentration-dependent uptake of ACV and GCV was observed in hOAT1- and hOCT1-expressing cells. Acyclovir 44-47 solute carrier family 22 member 6 Homo sapiens 72-77 11861798-6 2002 The Km values of ACV uptake by hOAT1 and hOCT1 were 342.3 and 151.2 microM, respectively, whereas those of GCV uptake by hOAT1 and hOCT1 were 895.5 and 516.2 microM, respectively. Acyclovir 17-20 solute carrier family 22 member 6 Homo sapiens 31-36 11861798-8 2002 In addition, probenecid weakly inhibited the hOAT1-mediated ACV uptake. Acyclovir 60-63 solute carrier family 22 member 6 Homo sapiens 45-50 11861798-9 2002 In conclusion, these results suggest that hOAT1 and hOCT1 mediate renal ACV and GCV transport, whereas hOAT1, hOAT2, hOAT3, and hOAT4 mediate renal AZT transport. Acyclovir 72-75 solute carrier family 22 member 6 Homo sapiens 42-47