PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11861777-3 2002 In the present study, the involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of pravastatin was investigated. Pravastatin 113-124 solute carrier family 22 member 8 Rattus norvegicus 74-79 11861777-3 2002 In the present study, the involvement of rat organic anion transporter 3 (rOat3; Slc22a8) in the renal uptake of pravastatin was investigated. Pravastatin 113-124 solute carrier family 22 member 8 Rattus norvegicus 81-88 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. p-Aminohippuric Acid 70-86 solute carrier family 22 member 6 Rattus norvegicus 0-5 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. p-Aminohippuric Acid 70-86 solute carrier family 22 member 8 Rattus norvegicus 11-16 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. p-Aminohippuric Acid 70-86 solute carrier family 22 member 6 Rattus norvegicus 189-194 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. p-Aminohippuric Acid 70-86 solute carrier family 22 member 8 Rattus norvegicus 233-238 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. p-Aminohippuric Acid 88-91 solute carrier family 22 member 6 Rattus norvegicus 0-5 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. p-Aminohippuric Acid 88-91 solute carrier family 22 member 8 Rattus norvegicus 11-16 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. p-Aminohippuric Acid 88-91 solute carrier family 22 member 6 Rattus norvegicus 189-194 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. p-Aminohippuric Acid 88-91 solute carrier family 22 member 8 Rattus norvegicus 233-238 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. Pravastatin 97-108 solute carrier family 22 member 6 Rattus norvegicus 0-5 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. Pravastatin 97-108 solute carrier family 22 member 8 Rattus norvegicus 11-16 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. Pravastatin 97-108 solute carrier family 22 member 6 Rattus norvegicus 189-194 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. Pravastatin 97-108 solute carrier family 22 member 8 Rattus norvegicus 233-238 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. p-Aminohippuric Acid 204-207 solute carrier family 22 member 6 Rattus norvegicus 0-5 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. p-Aminohippuric Acid 204-207 solute carrier family 22 member 8 Rattus norvegicus 11-16 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. Pravastatin 248-259 solute carrier family 22 member 6 Rattus norvegicus 0-5 11861777-5 2002 rOat1- and rOat3-expressed LLC-PK1 cells exhibited specific uptake of p-aminohippurate (PAH) and pravastatin, respectively, with the Michaelis-Menten constants (Km values) of 60 microM for rOat1-mediated PAH uptake and 13 microM for rOat3-mediated pravastatin uptake. Pravastatin 248-259 solute carrier family 22 member 8 Rattus norvegicus 11-16 11861777-8 2002 This was also supported by the difference in the degree of inhibition by benzylpenicillin, a relatively selective inhibitor of rOat3, for the uptake of PAH and pravastatin by kidney slices. Penicillin G 73-89 solute carrier family 22 member 8 Rattus norvegicus 127-132 11861777-8 2002 This was also supported by the difference in the degree of inhibition by benzylpenicillin, a relatively selective inhibitor of rOat3, for the uptake of PAH and pravastatin by kidney slices. p-Aminohippuric Acid 152-155 solute carrier family 22 member 8 Rattus norvegicus 127-132 11861777-8 2002 This was also supported by the difference in the degree of inhibition by benzylpenicillin, a relatively selective inhibitor of rOat3, for the uptake of PAH and pravastatin by kidney slices. Pravastatin 160-171 solute carrier family 22 member 8 Rattus norvegicus 127-132 11861777-9 2002 These results suggest that rOat1 and rOat3 are mainly responsible for the renal uptake of PAH and pravastatin, respectively. p-Aminohippuric Acid 90-93 solute carrier family 22 member 6 Rattus norvegicus 27-32 11861777-9 2002 These results suggest that rOat1 and rOat3 are mainly responsible for the renal uptake of PAH and pravastatin, respectively. p-Aminohippuric Acid 90-93 solute carrier family 22 member 8 Rattus norvegicus 37-42 11861777-9 2002 These results suggest that rOat1 and rOat3 are mainly responsible for the renal uptake of PAH and pravastatin, respectively. Pravastatin 98-109 solute carrier family 22 member 6 Rattus norvegicus 27-32 11861777-9 2002 These results suggest that rOat1 and rOat3 are mainly responsible for the renal uptake of PAH and pravastatin, respectively. Pravastatin 98-109 solute carrier family 22 member 8 Rattus norvegicus 37-42