PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11861510-1 2002 Somatostatin (SRIF) inhibits GH release from rat somatotropes by reducing adenylate cyclase (AC) activity and the free cytosolic calcium concentration ([Ca(2+)](i)). Calcium 129-136 somatostatin Sus scrofa 14-18 11861510-6 2002 Both 10(-7) and 10(-15) M SRIF increased cAMP, IP turnover, and [Ca(2+)](i) in HD cells. Cyclic AMP 41-45 somatostatin Sus scrofa 26-30 11861510-10 2002 Therefore, SRIF stimulates GH secretion from cultured porcine somatotrope subpopulations through an AC/cAMP pathway-dependent mechanism that is seemingly independent of net increases in IP turnover or [Ca(2+)](i). Cyclic AMP 103-107 somatostatin Sus scrofa 11-15