PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11779431-0	2001	Effect of all-trans retinoic acid and arsenic trioxide on tissue factor expression in acute promyelocytic leukemia cells.	Arsenic Trioxide	38-54	coagulation factor III, tissue factor	Homo sapiens	58-71	
11779431-1	2001	OBJECTIVE: To study the effect of all-trans retinoic acid (ATRA) and arsenic troxide (As2O3) on tissue factor (TF) expression and procoagulant activity (PCA) of acute promyelocytic leukemia (APL) cells in vivo and in vitro.	Arsenic Trioxide	86-91	coagulation factor III, tissue factor	Homo sapiens	96-109	
11779431-1	2001	OBJECTIVE: To study the effect of all-trans retinoic acid (ATRA) and arsenic troxide (As2O3) on tissue factor (TF) expression and procoagulant activity (PCA) of acute promyelocytic leukemia (APL) cells in vivo and in vitro.	Arsenic Trioxide	86-91	coagulation factor III, tissue factor	Homo sapiens	111-113	
11779431-5	2001	RESULTS: Both ATRA and As2O3 can down-regulate the TF antigen, its mRNA transcription and membrane PCA of APL cells in vivo and in vitro, in a time-dependent manner.	Arsenic Trioxide	23-28	coagulation factor III, tissue factor	Homo sapiens	51-53	
11779431-7	2001	Both ATRA and As2O3 can also down-regulate the TF antigen in U937 cells transfected with or without PML-RARa.	Arsenic Trioxide	14-19	coagulation factor III, tissue factor	Homo sapiens	47-49	
11779431-8	2001	CONCLUSION: Tissue factor expression and PCA in APL cells may be down-regulated by ATRA and As2O3.	Arsenic Trioxide	92-97	coagulation factor III, tissue factor	Homo sapiens	12-25	
11779431-9	2001	By down-regulating TF expression, As2O3 might also be used to improve the DIC-related hemorrhage in APL.	Arsenic Trioxide	34-39	coagulation factor III, tissue factor	Homo sapiens	19-21	
11779431-11	2001	The down-regulating effect of ATRA and As2O3 on TF expression in U937 cells might not involve this fusion protein.	Arsenic Trioxide	39-44	coagulation factor III, tissue factor	Homo sapiens	48-50