PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11740818-6 2001 PS-341 inhibits p44/42 mitogen-activated protein kinase (MAPK) growth signaling triggered by IL-6 and induces apoptosis, despite induction of p21 and p27, in p53 wild-type and p53 mutant MM cells. Bortezomib 0-6 interleukin 6 Homo sapiens 93-97 11740818-7 2001 PS-341 adds to the anti-MM activity of dexamethasone and overcomes IL-6-mediated protection against dexamethasone-induced apoptosis. Bortezomib 0-6 interleukin 6 Homo sapiens 67-71 11740818-8 2001 PS-341 blocks the paracrine growth of human MM cells by decreasing their adherence to BMSCs and related NF-kappaB-dependent induction of IL-6 secretion in BMSCs. Bortezomib 0-6 interleukin 6 Homo sapiens 137-141