PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11707432-4 2002 Pharmacological depletion of GM3 in adipocytes by an inhibitor of glucosylceramide synthase prevented the TNF-alpha-induced defect in insulin-dependent tyrosine phosphorylation of IRS-1 and also counteracted the TNF-alpha-induced serine phosphorylation of IRS-1. Tyrosine 152-160 tumor necrosis factor Rattus norvegicus 106-115