PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11457752-6 2001 Treatment of the hearts with losartan (4.5 micromol/L), an AT(1) blocker, or with tyrphostin AG490 (5 micromol/L), an inhibitor of JAK 2 phosphorylation, results in loss of the STAT/ANG promoter binding activity and an upregulated level of ANG mRNA. Tyrphostins 82-92 Janus kinase 2 Rattus norvegicus 131-136 11457752-7 2001 Hearts treated with the JAK 2 inhibitor tyrphostin AG490 showed a reduction in myocardial infarct size and in number of cardiomyocytes undergoing apoptosis. Tyrphostins 40-50 Janus kinase 2 Rattus norvegicus 24-29