PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11454948-3	2001	In the present study, we examined the effects of PD098059 and U0126, two structurally dissimilar inhibitors of MAP kinase kinase (MEK1/2), on the activation of ERK and Akt stimulated by human 5-hydroxytryptamine(1B) (serotonin) (5-HT1B) receptors.	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	49-57	AKT serine/threonine kinase 1	Homo sapiens	168-171	
11454948-9	2001	Nevertheless, our findings that PD098059 and U0126 inhibit activation of Akt at commonly used concentrations demonstrate that in at least some systems, these compounds inhibit activation of both ERK and Akt, and cannot be used to discern the relative roles of each pathway in mediating cellular responses.	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	32-40	AKT serine/threonine kinase 1	Homo sapiens	73-76	
11454948-9	2001	Nevertheless, our findings that PD098059 and U0126 inhibit activation of Akt at commonly used concentrations demonstrate that in at least some systems, these compounds inhibit activation of both ERK and Akt, and cannot be used to discern the relative roles of each pathway in mediating cellular responses.	2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one	32-40	AKT serine/threonine kinase 1	Homo sapiens	203-206