PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11352754-6 2001 We have identified the Phe176 (TM4), Tyr179 (TM4), Phe254 (TM6), and Phe259 (TM6) receptor residues as putatively interacting with the melanocortin-based ligand Phe(7) by differences between alpha-MSH and NDP-MSH agonist potencies. 3-hydroxy-2-methyl-4H-pyran-4-thione 45-48 pro-opiomelanocortin-alpha Mus musculus 191-200 11352754-6 2001 We have identified the Phe176 (TM4), Tyr179 (TM4), Phe254 (TM6), and Phe259 (TM6) receptor residues as putatively interacting with the melanocortin-based ligand Phe(7) by differences between alpha-MSH and NDP-MSH agonist potencies. 3-hydroxy-2-methyl-4H-pyran-4-thione 45-48 Norrie disease (pseudoglioma) (human) Mus musculus 205-208 11352754-6 2001 We have identified the Phe176 (TM4), Tyr179 (TM4), Phe254 (TM6), and Phe259 (TM6) receptor residues as putatively interacting with the melanocortin-based ligand Phe(7) by differences between alpha-MSH and NDP-MSH agonist potencies. 3-hydroxy-2-methyl-4H-pyran-4-thione 45-48 msh homeobox 1 Mus musculus 197-200 11352754-6 2001 We have identified the Phe176 (TM4), Tyr179 (TM4), Phe254 (TM6), and Phe259 (TM6) receptor residues as putatively interacting with the melanocortin-based ligand Phe(7) by differences between alpha-MSH and NDP-MSH agonist potencies. tm6 59-62 pro-opiomelanocortin-alpha Mus musculus 191-200 11352754-6 2001 We have identified the Phe176 (TM4), Tyr179 (TM4), Phe254 (TM6), and Phe259 (TM6) receptor residues as putatively interacting with the melanocortin-based ligand Phe(7) by differences between alpha-MSH and NDP-MSH agonist potencies. tm6 59-62 Norrie disease (pseudoglioma) (human) Mus musculus 205-208 11352754-6 2001 We have identified the Phe176 (TM4), Tyr179 (TM4), Phe254 (TM6), and Phe259 (TM6) receptor residues as putatively interacting with the melanocortin-based ligand Phe(7) by differences between alpha-MSH and NDP-MSH agonist potencies. tm6 59-62 msh homeobox 1 Mus musculus 197-200 11352754-6 2001 We have identified the Phe176 (TM4), Tyr179 (TM4), Phe254 (TM6), and Phe259 (TM6) receptor residues as putatively interacting with the melanocortin-based ligand Phe(7) by differences between alpha-MSH and NDP-MSH agonist potencies. Phenylalanine 23-26 pro-opiomelanocortin-alpha Mus musculus 191-200 11352754-6 2001 We have identified the Phe176 (TM4), Tyr179 (TM4), Phe254 (TM6), and Phe259 (TM6) receptor residues as putatively interacting with the melanocortin-based ligand Phe(7) by differences between alpha-MSH and NDP-MSH agonist potencies. Phenylalanine 23-26 Norrie disease (pseudoglioma) (human) Mus musculus 205-208 11352754-6 2001 We have identified the Phe176 (TM4), Tyr179 (TM4), Phe254 (TM6), and Phe259 (TM6) receptor residues as putatively interacting with the melanocortin-based ligand Phe(7) by differences between alpha-MSH and NDP-MSH agonist potencies. Phenylalanine 23-26 msh homeobox 1 Mus musculus 197-200 11352754-11 2001 Melanocortin-based peptides modified at the 7 position of MTII with DPhe, DNal(1"), Nal(2"), and DNal(2") have been pharmacologically characterized at these mutant mouse MC4Rs. D-phenylalanine 68-72 metallothionein 2 Mus musculus 58-62 11352754-12 2001 These data suggest a revised hypothesis for the mechanism of SHU9119 antagonism at the MC4R which may be attributed to the presence of a "bulky" naphthyl moiety at the 7 position (original hypothesis), and additionally that both the stereochemistry and naphthyl ring position (2" versus 1") are important for positioning of the ligand Arg(8) residue with the corresponding mMC4R amino acids. Arginine 335-338 melanocortin 4 receptor Mus musculus 87-91