PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11285260-0	2001	Maintenance of CDC42 GDP-bound state by Rho-GDI inhibits MAP kinase activation by the exchange factor Ras-GRF.	Guanosine Diphosphate	21-24	cell division cycle 42	Homo sapiens	15-20	
11285260-4	2001	Here, we report that retaining Cdc42 in its GDP-bound state by overexpressing Rho-GDI inhibits Ras-GRF-mediated MAPK activation.	Guanosine Diphosphate	44-47	cell division cycle 42	Homo sapiens	31-36	
11285260-7	2001	In contrast, promoting GDP release from Cdc42 with the Rho family GEF Dbl or with ionomycin suppressed the restraint exerted by Cdc42 on Ras-GRF activity.	Guanosine Diphosphate	23-26	cell division cycle 42	Homo sapiens	40-45	
11285260-7	2001	In contrast, promoting GDP release from Cdc42 with the Rho family GEF Dbl or with ionomycin suppressed the restraint exerted by Cdc42 on Ras-GRF activity.	Guanosine Diphosphate	23-26	cell division cycle 42	Homo sapiens	128-133	
11285260-9	2001	Interestingly, the loss of the GDP-bound state by Cdc42 abolishes its inhibitory effects on Ras-GRF function.	Guanosine Diphosphate	31-34	cell division cycle 42	Homo sapiens	50-55