PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11257444-4	2001	Hypoxia dramatically increased phosphorylation of Akt (Ser(473)).	Serine	55-58	AKT serine/threonine kinase 1	Rattus norvegicus	50-53	
11257444-6	2001	The effect of hypoxia on phosphorylation of Akt was completely blocked by pretreatment of the cells with wortmannin (100 nM), indicating that this effect is mediated by phosphatidylinositol 3-kinase (P13K).	Wortmannin	105-115	AKT serine/threonine kinase 1	Rattus norvegicus	44-47	
11257444-7	2001	In contrast, whereas hypoxia also strongly induced phosphorylation of the transcription factors CREB and EPAS1, these effects persisted in the presence of wortmannin.	Wortmannin	155-165	cAMP responsive element binding protein 1	Rattus norvegicus	96-100	
11257444-7	2001	In contrast, whereas hypoxia also strongly induced phosphorylation of the transcription factors CREB and EPAS1, these effects persisted in the presence of wortmannin.	Wortmannin	155-165	endothelial PAS domain protein 1	Rattus norvegicus	105-110