PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11078728-1 2001 Serine protease activation is typically controlled by proteolytic cleavage of the scissile bond, resulting in spontaneous formation of the activating Ile(16)-Asp(194) salt bridge. Isoleucine 150-153 coagulation factor II, thrombin Homo sapiens 0-15