PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 11073718-1 2000 The enzyme 4-hydroxyphenylpyruvic acid dioxygenase (HPD) catalyzes the reaction of 4-hydroxyphenylpyruvic acid to homogentisic acid in the tyrosine catabolism pathway. Tyrosine 139-147 4-hydroxyphenylpyruvate dioxygenase Homo sapiens 11-50 11073718-1 2000 The enzyme 4-hydroxyphenylpyruvic acid dioxygenase (HPD) catalyzes the reaction of 4-hydroxyphenylpyruvic acid to homogentisic acid in the tyrosine catabolism pathway. Tyrosine 139-147 4-hydroxyphenylpyruvate dioxygenase Homo sapiens 52-55 11073718-2 2000 A deficiency in the catalytic activity of HPD may lead to tyrosinemia type III, an autosomal recessive disorder characterized by elevated levels of blood tyrosine and massive excretion of tyrosine derivatives into urine. Tyrosine 58-66 4-hydroxyphenylpyruvate dioxygenase Homo sapiens 42-45 11073718-2 2000 A deficiency in the catalytic activity of HPD may lead to tyrosinemia type III, an autosomal recessive disorder characterized by elevated levels of blood tyrosine and massive excretion of tyrosine derivatives into urine. Tyrosine 154-162 4-hydroxyphenylpyruvate dioxygenase Homo sapiens 42-45