PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
11071366-0	2000	Oxidative inactivation of brain ecto-5"-nucleotidase by thiols/Fe2+ system.	Sulfhydryl Compounds	56-62	5'-nucleotidase	Bos taurus	32-52	
11071366-10	2000	Overall, thiols, expressing more inhibitory effect on the activity of 5"-nucleotidase, were found to be more effective in potentiating the Fe2+-mediated inactivation.	Sulfhydryl Compounds	9-15	5'-nucleotidase	Bos taurus	70-85	
11071366-11	2000	Further, kinetic analyses indicate that Fe2+ and thiols inhibit the 5"-nucleotidase in a competitive or uncompetitive manner, respectively.	Sulfhydryl Compounds	49-55	5'-nucleotidase	Bos taurus	68-83	
11071366-12	2000	These results suggest that ecto-5"-nucleotidase from brain membrane is one of proteins susceptible to thiols/Fe2+-catalyzed oxidation, and the oxidative inactivation may be related to the selective association of Fe2+ and thiols to the enzyme molecule.	Sulfhydryl Compounds	102-108	5'-nucleotidase	Bos taurus	27-47	
11071366-12	2000	These results suggest that ecto-5"-nucleotidase from brain membrane is one of proteins susceptible to thiols/Fe2+-catalyzed oxidation, and the oxidative inactivation may be related to the selective association of Fe2+ and thiols to the enzyme molecule.	Sulfhydryl Compounds	222-228	5'-nucleotidase	Bos taurus	27-47