PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10988358-2 2000 In vivo studies demonstrated that pretreatment of mice with DFX reduces tumor necrosis factor alpha (TNF-alpha) serum levels and increases the rate of survival of mice inoculated with lethal doses of lipopolysaccharide (LPS) or Escherichia coli O111:B4. Deferoxamine 60-63 tumor necrosis factor Mus musculus 72-99 10988358-2 2000 In vivo studies demonstrated that pretreatment of mice with DFX reduces tumor necrosis factor alpha (TNF-alpha) serum levels and increases the rate of survival of mice inoculated with lethal doses of lipopolysaccharide (LPS) or Escherichia coli O111:B4. Deferoxamine 60-63 tumor necrosis factor Mus musculus 101-110 10988358-4 2000 On the other hand, DFX prevents mortality induced either by LPS or murine recombinant TNF-alpha in D(+)-galactosamine (GalN)-sensitized mice. Deferoxamine 19-22 tumor necrosis factor Mus musculus 86-95 10988358-5 2000 These protective actions of DFX correlate with an attenuated tissue damage observed in lungs, livers and kidneys of LPS-treated animals and GalN-sensitized mice inoculated with TNF-alpha. Deferoxamine 28-31 tumor necrosis factor Mus musculus 177-186