PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10972232-2	2000	The mechanism of action of cyclosporine and tacrolimus has been explained on the basis of their inhibition of interleukin-2 (IL-2), and induction of transforming growth factor-beta (TGF-beta).	Tacrolimus	44-54	transforming growth factor beta 1	Homo sapiens	149-180	
10972232-2	2000	The mechanism of action of cyclosporine and tacrolimus has been explained on the basis of their inhibition of interleukin-2 (IL-2), and induction of transforming growth factor-beta (TGF-beta).	Tacrolimus	44-54	transforming growth factor beta 1	Homo sapiens	182-190	
10972232-5	2000	RESULTS: In this study, we report that rapamycin in combination with either tacrolimus or cyclosporine significantly inhibited the lymphocyte proliferation, IL-2 expression, and induced TGF-beta, compared with these drugs alone.	Tacrolimus	76-86	transforming growth factor beta 1	Homo sapiens	186-194