PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10930377-0	2000	Gastrointestinal glutathione peroxidase prevents transport of lipid hydroperoxides in CaCo-2 cells.	Lipid Peroxides	62-82	glutathione peroxidase 2	Homo sapiens	0-39	
10930377-1	2000	BACKGROUND & AIMS: Gastrointestinal glutathione peroxidase (GI-GPx), 1 of the 4 types of selenium-dependent glutathione peroxidases, is expressed exclusively in the gastrointestinal system and has therefore been suggested to function as a barrier against the absorption of dietary hydroperoxides.	Adenosine Monophosphate	12-15	glutathione peroxidase 2	Homo sapiens	23-62	
10930377-1	2000	BACKGROUND & AIMS: Gastrointestinal glutathione peroxidase (GI-GPx), 1 of the 4 types of selenium-dependent glutathione peroxidases, is expressed exclusively in the gastrointestinal system and has therefore been suggested to function as a barrier against the absorption of dietary hydroperoxides.	Adenosine Monophosphate	12-15	glutathione peroxidase 2	Homo sapiens	64-70	
10930377-1	2000	BACKGROUND & AIMS: Gastrointestinal glutathione peroxidase (GI-GPx), 1 of the 4 types of selenium-dependent glutathione peroxidases, is expressed exclusively in the gastrointestinal system and has therefore been suggested to function as a barrier against the absorption of dietary hydroperoxides.	Selenium	93-101	glutathione peroxidase 2	Homo sapiens	23-62	
10930377-1	2000	BACKGROUND & AIMS: Gastrointestinal glutathione peroxidase (GI-GPx), 1 of the 4 types of selenium-dependent glutathione peroxidases, is expressed exclusively in the gastrointestinal system and has therefore been suggested to function as a barrier against the absorption of dietary hydroperoxides.	Selenium	93-101	glutathione peroxidase 2	Homo sapiens	64-70	
10930377-1	2000	BACKGROUND & AIMS: Gastrointestinal glutathione peroxidase (GI-GPx), 1 of the 4 types of selenium-dependent glutathione peroxidases, is expressed exclusively in the gastrointestinal system and has therefore been suggested to function as a barrier against the absorption of dietary hydroperoxides.	Hydrogen Peroxide	285-299	glutathione peroxidase 2	Homo sapiens	23-62	
10930377-1	2000	BACKGROUND & AIMS: Gastrointestinal glutathione peroxidase (GI-GPx), 1 of the 4 types of selenium-dependent glutathione peroxidases, is expressed exclusively in the gastrointestinal system and has therefore been suggested to function as a barrier against the absorption of dietary hydroperoxides.	Hydrogen Peroxide	285-299	glutathione peroxidase 2	Homo sapiens	64-70	
10930377-2	2000	METHODS: The selenium-dependent expression of GI-GPx and cytosolic GPx (cGPx) was analyzed by Western blotting.	Selenium	13-21	glutathione peroxidase 2	Homo sapiens	46-52	
10930377-3	2000	Transport of 13-hydroperoxy octadecadienoic acid (13-HPODE) was investigated in a CaCo-2 cell monolayer modulated in GI-GPx and cGPx by selenium restriction or repletion.	13-hydroperoxy octadecadienoic acid	13-48	glutathione peroxidase 2	Homo sapiens	117-123	
10930377-3	2000	Transport of 13-hydroperoxy octadecadienoic acid (13-HPODE) was investigated in a CaCo-2 cell monolayer modulated in GI-GPx and cGPx by selenium restriction or repletion.	13-Hpode	50-58	glutathione peroxidase 2	Homo sapiens	117-123	
10930377-5	2000	RESULTS: Low but significant GI-GPx levels were detected in selenium-deficient CaCo-2 cells and in the gastrointestinal tract of selenium-deficient rats, whereas cGPx was completely absent.	Selenium	60-68	glutathione peroxidase 2	Homo sapiens	29-35	
10930377-5	2000	RESULTS: Low but significant GI-GPx levels were detected in selenium-deficient CaCo-2 cells and in the gastrointestinal tract of selenium-deficient rats, whereas cGPx was completely absent.	Selenium	129-137	glutathione peroxidase 2	Homo sapiens	29-35	
10930377-6	2000	Selenium supplementation of CaCo-2 cells resulted in a 5-fold increase of GI-GPx protein, whereas total GPx activity increased by a factor of 13, with most of the GPx activity under selenium-adequate conditions being cGPx.	Selenium	0-8	glutathione peroxidase 2	Homo sapiens	74-80	
10930377-10	2000	CONCLUSIONS: Low GI-GPx levels, as present in selenium deficiency, suffice to prevent transport of 13-HPODE.	Selenium	46-54	glutathione peroxidase 2	Homo sapiens	17-23	
10930377-11	2000	GI-GPx may thus function as a barrier against hydroperoxide absorption.	Hydrogen Peroxide	46-59	glutathione peroxidase 2	Homo sapiens	0-6