PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10928947-7 2000 The results suggest that the inhibitory actions of PTU on testosterone secretion are exerted, at least in part, at the testicular level through a mechanism which is independent of thyroid status and which involves a reduction in P450scc activity and, hence, in the conversion of cholesterol to pregnenolone. Propylthiouracil 51-54 cytochrome P450, family 11, subfamily a, polypeptide 1 Rattus norvegicus 229-236