PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10833508-0 2000 TrkB activation by brain-derived neurotrophic factor inhibits the G protein-gated inward rectifier Kir3 by tyrosine phosphorylation of the channel. Tyrosine 107-115 neurotrophic receptor tyrosine kinase 2 Homo sapiens 0-4 10833508-0 2000 TrkB activation by brain-derived neurotrophic factor inhibits the G protein-gated inward rectifier Kir3 by tyrosine phosphorylation of the channel. Tyrosine 107-115 brain derived neurotrophic factor Homo sapiens 19-52 10833508-4 2000 The general tyrosine kinase inhibitors genistein, Go 6976, and K252a but not the serine/threonine kinase inhibitor staurosporine blocked the BDNF-induced inhibition of the channel. Genistein 39-48 brain derived neurotrophic factor Homo sapiens 141-145 10833508-4 2000 The general tyrosine kinase inhibitors genistein, Go 6976, and K252a but not the serine/threonine kinase inhibitor staurosporine blocked the BDNF-induced inhibition of the channel. Go 6976 50-57 brain derived neurotrophic factor Homo sapiens 141-145 10833508-4 2000 The general tyrosine kinase inhibitors genistein, Go 6976, and K252a but not the serine/threonine kinase inhibitor staurosporine blocked the BDNF-induced inhibition of the channel. staurosporine aglycone 63-68 brain derived neurotrophic factor Homo sapiens 141-145 10833508-5 2000 BDNF was also found to directly stimulate channel phosphorylation because Kir3.1 immunoprecipitated from BDNF-stimulated cells showed enhanced labeling by anti-phosphotyrosine-specific antibodies. Phosphotyrosine 160-175 brain derived neurotrophic factor Homo sapiens 0-4 10833508-5 2000 BDNF was also found to directly stimulate channel phosphorylation because Kir3.1 immunoprecipitated from BDNF-stimulated cells showed enhanced labeling by anti-phosphotyrosine-specific antibodies. Phosphotyrosine 160-175 potassium inwardly rectifying channel subfamily J member 3 Homo sapiens 74-80 10833508-5 2000 BDNF was also found to directly stimulate channel phosphorylation because Kir3.1 immunoprecipitated from BDNF-stimulated cells showed enhanced labeling by anti-phosphotyrosine-specific antibodies. Phosphotyrosine 160-175 brain derived neurotrophic factor Homo sapiens 105-109 10833508-6 2000 The BDNF effect required specific tyrosine residues in the amino terminus of Kir3.1 and Kir3.4 channels. Tyrosine 34-42 brain derived neurotrophic factor Homo sapiens 4-8 10833508-6 2000 The BDNF effect required specific tyrosine residues in the amino terminus of Kir3.1 and Kir3.4 channels. Tyrosine 34-42 potassium inwardly rectifying channel subfamily J member 3 Homo sapiens 77-83 10833508-8 2000 4 channels to phenylalanine significantly blocked the BDNF-induced inhibition. Phenylalanine 27-40 brain derived neurotrophic factor Homo sapiens 67-71 10833508-9 2000 The insensitive Kir3.2 was made sensitive to BDNF by adding a tyrosine (D41Y) and a lysine (P32K) upstream to generate a phosphorylation site motif analogous to that present in Kir3.4. Tyrosine 62-70 potassium inwardly rectifying channel subfamily J member 6 Homo sapiens 16-22 10833508-9 2000 The insensitive Kir3.2 was made sensitive to BDNF by adding a tyrosine (D41Y) and a lysine (P32K) upstream to generate a phosphorylation site motif analogous to that present in Kir3.4. Tyrosine 62-70 brain derived neurotrophic factor Homo sapiens 45-49 10833508-9 2000 The insensitive Kir3.2 was made sensitive to BDNF by adding a tyrosine (D41Y) and a lysine (P32K) upstream to generate a phosphorylation site motif analogous to that present in Kir3.4. Lysine 84-90 potassium inwardly rectifying channel subfamily J member 6 Homo sapiens 16-22 10833508-9 2000 The insensitive Kir3.2 was made sensitive to BDNF by adding a tyrosine (D41Y) and a lysine (P32K) upstream to generate a phosphorylation site motif analogous to that present in Kir3.4. Lysine 84-90 brain derived neurotrophic factor Homo sapiens 45-49 10833508-10 2000 These results suggest that neurotrophin activation of TrkB receptors may physiologically control neuronal excitability by direct tyrosine phosphorylation of the Kir3.1 and Kir3.4 subunits of G protein-gated inwardly rectifying potassium channels. Tyrosine 129-137 brain derived neurotrophic factor Homo sapiens 27-39 10833508-10 2000 These results suggest that neurotrophin activation of TrkB receptors may physiologically control neuronal excitability by direct tyrosine phosphorylation of the Kir3.1 and Kir3.4 subunits of G protein-gated inwardly rectifying potassium channels. Tyrosine 129-137 neurotrophic receptor tyrosine kinase 2 Homo sapiens 54-58 10833508-10 2000 These results suggest that neurotrophin activation of TrkB receptors may physiologically control neuronal excitability by direct tyrosine phosphorylation of the Kir3.1 and Kir3.4 subunits of G protein-gated inwardly rectifying potassium channels. Tyrosine 129-137 potassium inwardly rectifying channel subfamily J member 3 Homo sapiens 161-167