PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10830164-1 2000 The ryanodine receptor (RyR)/calcium release channel on the sarcoplasmic reticulum (SR) is the major source of calcium (Ca2+) required for cardiac muscle excitation-contraction (EC) coupling. Calcium 29-36 ryanodine receptor 2 Homo sapiens 4-22 10830164-1 2000 The ryanodine receptor (RyR)/calcium release channel on the sarcoplasmic reticulum (SR) is the major source of calcium (Ca2+) required for cardiac muscle excitation-contraction (EC) coupling. Calcium 29-36 ryanodine receptor 2 Homo sapiens 24-27 10830164-2 2000 The channel is a tetramer comprised of four type 2 RyR polypeptides (RyR2) and four FK506 binding proteins (FKBP12.6). Tacrolimus 84-89 FKBP prolyl isomerase 1B Homo sapiens 108-116