PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10807739-6 2000 JNK and ERK were activated by ET-1 binding to a single receptor (ET-1A) but differed in their downstream mechanisms: only JNK activation was sensitive to the radical scavenger N-acetylcysteine and diphenylene iodonium, an inhibitor of NADPH oxidase, indicating a role for ROS. Acetylcysteine 176-192 mitogen-activated protein kinase 8 Rattus norvegicus 0-3 10807739-6 2000 JNK and ERK were activated by ET-1 binding to a single receptor (ET-1A) but differed in their downstream mechanisms: only JNK activation was sensitive to the radical scavenger N-acetylcysteine and diphenylene iodonium, an inhibitor of NADPH oxidase, indicating a role for ROS. Acetylcysteine 176-192 mitogen-activated protein kinase 8 Rattus norvegicus 122-125