PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10744670-0	2000	p-hydroxyphenylacetaldehyde, an aldehyde generated by myeloperoxidase, modifies phospholipid amino groups of low density lipoprotein in human atherosclerotic intima.	4-hydroxyphenylacetaldehyde	0-27	myeloperoxidase	Homo sapiens	54-69	
10744670-0	2000	p-hydroxyphenylacetaldehyde, an aldehyde generated by myeloperoxidase, modifies phospholipid amino groups of low density lipoprotein in human atherosclerotic intima.	Aldehydes	19-27	myeloperoxidase	Homo sapiens	54-69	
10744670-0	2000	p-hydroxyphenylacetaldehyde, an aldehyde generated by myeloperoxidase, modifies phospholipid amino groups of low density lipoprotein in human atherosclerotic intima.	Phospholipids	80-92	myeloperoxidase	Homo sapiens	54-69	
10744670-4	2000	We previously showed that p-hydroxyphenylacetaldehyde (pHA) is the major product of L-tyrosine oxidation by the myeloperoxidase/hydrogen peroxide/chloride system of phagocytes.	4-hydroxyphenylacetaldehyde	26-53	lamin B receptor	Homo sapiens	55-58	
10744670-4	2000	We previously showed that p-hydroxyphenylacetaldehyde (pHA) is the major product of L-tyrosine oxidation by the myeloperoxidase/hydrogen peroxide/chloride system of phagocytes.	4-hydroxyphenylacetaldehyde	26-53	myeloperoxidase	Homo sapiens	112-127	
10744670-4	2000	We previously showed that p-hydroxyphenylacetaldehyde (pHA) is the major product of L-tyrosine oxidation by the myeloperoxidase/hydrogen peroxide/chloride system of phagocytes.	Tyrosine	84-94	lamin B receptor	Homo sapiens	55-58	
10744670-4	2000	We previously showed that p-hydroxyphenylacetaldehyde (pHA) is the major product of L-tyrosine oxidation by the myeloperoxidase/hydrogen peroxide/chloride system of phagocytes.	Tyrosine	84-94	myeloperoxidase	Homo sapiens	112-127	
10744670-4	2000	We previously showed that p-hydroxyphenylacetaldehyde (pHA) is the major product of L-tyrosine oxidation by the myeloperoxidase/hydrogen peroxide/chloride system of phagocytes.	Hydrogen Peroxide	128-145	lamin B receptor	Homo sapiens	55-58	
10744670-4	2000	We previously showed that p-hydroxyphenylacetaldehyde (pHA) is the major product of L-tyrosine oxidation by the myeloperoxidase/hydrogen peroxide/chloride system of phagocytes.	Hydrogen Peroxide	128-145	myeloperoxidase	Homo sapiens	112-127	
10744670-4	2000	We previously showed that p-hydroxyphenylacetaldehyde (pHA) is the major product of L-tyrosine oxidation by the myeloperoxidase/hydrogen peroxide/chloride system of phagocytes.	Chlorides	146-154	lamin B receptor	Homo sapiens	55-58	
10744670-4	2000	We previously showed that p-hydroxyphenylacetaldehyde (pHA) is the major product of L-tyrosine oxidation by the myeloperoxidase/hydrogen peroxide/chloride system of phagocytes.	Chlorides	146-154	myeloperoxidase	Homo sapiens	112-127	
10744670-6	2000	Activated human neutrophils generated pHA-ethanolamine, the reduced adduct of pHA with the amino group of phosphatidylethanolamine, on LDL phospholipids by a reaction that required myeloperoxidase, H(2)O(2), and L-tyrosine.	Ethanolamine	42-54	lamin B receptor	Homo sapiens	38-41	
10744670-6	2000	Activated human neutrophils generated pHA-ethanolamine, the reduced adduct of pHA with the amino group of phosphatidylethanolamine, on LDL phospholipids by a reaction that required myeloperoxidase, H(2)O(2), and L-tyrosine.	Ethanolamine	42-54	lamin B receptor	Homo sapiens	78-81	
10744670-6	2000	Activated human neutrophils generated pHA-ethanolamine, the reduced adduct of pHA with the amino group of phosphatidylethanolamine, on LDL phospholipids by a reaction that required myeloperoxidase, H(2)O(2), and L-tyrosine.	Ethanolamine	42-54	myeloperoxidase	Homo sapiens	181-196	
10744670-6	2000	Activated human neutrophils generated pHA-ethanolamine, the reduced adduct of pHA with the amino group of phosphatidylethanolamine, on LDL phospholipids by a reaction that required myeloperoxidase, H(2)O(2), and L-tyrosine.	phosphatidylethanolamine	106-130	lamin B receptor	Homo sapiens	38-41	
10744670-6	2000	Activated human neutrophils generated pHA-ethanolamine, the reduced adduct of pHA with the amino group of phosphatidylethanolamine, on LDL phospholipids by a reaction that required myeloperoxidase, H(2)O(2), and L-tyrosine.	phosphatidylethanolamine	106-130	myeloperoxidase	Homo sapiens	181-196	
10744670-6	2000	Activated human neutrophils generated pHA-ethanolamine, the reduced adduct of pHA with the amino group of phosphatidylethanolamine, on LDL phospholipids by a reaction that required myeloperoxidase, H(2)O(2), and L-tyrosine.	Phospholipids	139-152	lamin B receptor	Homo sapiens	38-41	
10744670-6	2000	Activated human neutrophils generated pHA-ethanolamine, the reduced adduct of pHA with the amino group of phosphatidylethanolamine, on LDL phospholipids by a reaction that required myeloperoxidase, H(2)O(2), and L-tyrosine.	Phospholipids	139-152	lamin B receptor	Homo sapiens	78-81	
10744670-6	2000	Activated human neutrophils generated pHA-ethanolamine, the reduced adduct of pHA with the amino group of phosphatidylethanolamine, on LDL phospholipids by a reaction that required myeloperoxidase, H(2)O(2), and L-tyrosine.	Phospholipids	139-152	myeloperoxidase	Homo sapiens	181-196	
10744670-6	2000	Activated human neutrophils generated pHA-ethanolamine, the reduced adduct of pHA with the amino group of phosphatidylethanolamine, on LDL phospholipids by a reaction that required myeloperoxidase, H(2)O(2), and L-tyrosine.	Hydrogen Peroxide	198-206	lamin B receptor	Homo sapiens	38-41	
10744670-6	2000	Activated human neutrophils generated pHA-ethanolamine, the reduced adduct of pHA with the amino group of phosphatidylethanolamine, on LDL phospholipids by a reaction that required myeloperoxidase, H(2)O(2), and L-tyrosine.	Hydrogen Peroxide	198-206	lamin B receptor	Homo sapiens	78-81	
10744670-6	2000	Activated human neutrophils generated pHA-ethanolamine, the reduced adduct of pHA with the amino group of phosphatidylethanolamine, on LDL phospholipids by a reaction that required myeloperoxidase, H(2)O(2), and L-tyrosine.	Tyrosine	212-222	lamin B receptor	Homo sapiens	38-41	
10744670-6	2000	Activated human neutrophils generated pHA-ethanolamine, the reduced adduct of pHA with the amino group of phosphatidylethanolamine, on LDL phospholipids by a reaction that required myeloperoxidase, H(2)O(2), and L-tyrosine.	Tyrosine	212-222	lamin B receptor	Homo sapiens	78-81	
10744670-7	2000	The cellular system could be replaced by HOCl and L-tyrosine but not by a wide variety of other oxidation systems, indicating that pHA-ethanolamine is a specific marker for covalent modification of aminophospholipids by myeloperoxidase.	aminophospholipids	198-216	lamin B receptor	Homo sapiens	131-134	
10744670-7	2000	The cellular system could be replaced by HOCl and L-tyrosine but not by a wide variety of other oxidation systems, indicating that pHA-ethanolamine is a specific marker for covalent modification of aminophospholipids by myeloperoxidase.	aminophospholipids	198-216	myeloperoxidase	Homo sapiens	220-235	
10744670-10	2000	In contrast, the concentration of pHA-ethanolamine in LDL isolated from human atherosclerotic lesions was strikingly elevated (4.5 mmol/mol).	Ethanolamine	38-50	lamin B receptor	Homo sapiens	34-37	
10744670-11	2000	Collectively, these results demonstrate a novel, myeloperoxidase-based mechanism for modifying the amino group of LDL phospholipids.	Phospholipids	118-131	myeloperoxidase	Homo sapiens	49-64	
10744670-12	2000	They also offer the first evidence that myeloperoxidase may damage LDL lipids in vivo, raising the possibility that aldehyde-modified aminophospholipids play a role in inflammation and vascular disease.	Aldehydes	116-124	myeloperoxidase	Homo sapiens	40-55	
10744670-12	2000	They also offer the first evidence that myeloperoxidase may damage LDL lipids in vivo, raising the possibility that aldehyde-modified aminophospholipids play a role in inflammation and vascular disease.	aminophospholipids	134-152	myeloperoxidase	Homo sapiens	40-55