PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10719211-2 2000 In this study, we analyzed the effects of acute and chronic cocaine and morphine on mRNAs encoding the NGFI-B/Nur77 family of nuclear orphan receptors in reward pathways in Fischer and Lewis rats. Cocaine 60-67 nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus 103-109 10719211-2 2000 In this study, we analyzed the effects of acute and chronic cocaine and morphine on mRNAs encoding the NGFI-B/Nur77 family of nuclear orphan receptors in reward pathways in Fischer and Lewis rats. Cocaine 60-67 nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus 110-115 10719211-2 2000 In this study, we analyzed the effects of acute and chronic cocaine and morphine on mRNAs encoding the NGFI-B/Nur77 family of nuclear orphan receptors in reward pathways in Fischer and Lewis rats. Morphine 72-80 nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus 103-109 10719211-2 2000 In this study, we analyzed the effects of acute and chronic cocaine and morphine on mRNAs encoding the NGFI-B/Nur77 family of nuclear orphan receptors in reward pathways in Fischer and Lewis rats. Morphine 72-80 nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus 110-115 10719211-3 2000 After a single injection of cocaine, a similar upregulation of NGFI-B mRNA in striatal subregions and cortex cinguli was seen in both Fischer and Lewis rats. Cocaine 28-35 nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus 63-69 10719211-5 2000 Morphine increased NGFI-B mRNA in medial caudate putamen and cortex cinguli in Lewis rats and Nor1 mRNA in medial caudate putamen in Fischer rats. Morphine 0-8 nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus 19-25 10719211-6 2000 Chronic cocaine upregulated NGFI-B mRNA in nucleus accumbens core, lateral caudate putamen and cingulate cortex in Fischer rats, whereas no effect was seen in Lewis rats. Cocaine 8-15 nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus 28-34 10719211-9 2000 Our results demonstrate different responses in addiction-prone Lewis rats as compared to the less addiction-prone Fischer rats with respect to NGFI-B and Nor1 mRNA regulation after acute and repeated administration of cocaine and morphine. Cocaine 218-225 nuclear receptor subfamily 4, group A, member 1 Rattus norvegicus 143-149