PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10697568-0	1999	Taxotere activates transcription factor AP-1 in association with apoptotic cell death in gastric cancer cell lines.	Docetaxel	0-8	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	40-44	
10697568-1	1999	We investigated whether a novel mitotic inhibitor, taxotere can activate the transcription factor AP-1 in association with apoptotic cell death in 8 gastric cancer cell lines.	Docetaxel	51-59	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	98-102	
10697568-3	1999	The activation of AP-1 binding was induced in accordance with the sensitivity to taxotere in gastric cancer cell lines.	Docetaxel	81-89	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	18-22	
10697568-4	1999	The relationship between the increase of AP-1 binding and the formation of internucleosomal DNA ladders induced by taxotere was significant (p < 0.05).	Docetaxel	115-123	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	41-45	
10697568-5	1999	Furthermore, the activation of AP-1 binding was induced following the treatment of taxotere in a dose and -time dependent manner.	Docetaxel	83-91	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	31-35	
10697568-8	1999	These results indicate that the activation of AP-1 binding by taxotere seems to be an important factor in determining its sensitivity in association with internucleosomal DNA ladders, and suggest that the induction of gadd153 gene could be a downstream target of AP-1-regulated genes involved in signal transduction pathways leading to apoptosis in gastric cancer cells.	Docetaxel	62-70	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	46-50	
10697568-8	1999	These results indicate that the activation of AP-1 binding by taxotere seems to be an important factor in determining its sensitivity in association with internucleosomal DNA ladders, and suggest that the induction of gadd153 gene could be a downstream target of AP-1-regulated genes involved in signal transduction pathways leading to apoptosis in gastric cancer cells.	Docetaxel	62-70	DNA damage inducible transcript 3	Homo sapiens	218-225	
10697568-8	1999	These results indicate that the activation of AP-1 binding by taxotere seems to be an important factor in determining its sensitivity in association with internucleosomal DNA ladders, and suggest that the induction of gadd153 gene could be a downstream target of AP-1-regulated genes involved in signal transduction pathways leading to apoptosis in gastric cancer cells.	Docetaxel	62-70	JunB proto-oncogene, AP-1 transcription factor subunit	Homo sapiens	263-267