PMID-sentid	Pub_year	Sent_text		comp_official_name	comp_offsetprotein_name	organism	prot_offset
10681520-4	2000	Tyrosine phosphorylation of Ras-GRF1 is critical for the induction of Rac-GEF activity as evidenced by inhibition by tyrosine kinase inhibitors.	Tyrosine	0-8	Ras protein specific guanine nucleotide releasing factor 1	Homo sapiens	28-36	
10681520-6	2000	Ras-GRF1 transiently expressed with v-Src was tyrosine-phosphorylated and showed significant GEF activity toward Rac, but not Rho and Cdc42, which was comparable with that induced by Gbetagamma.	Tyrosine	46-54	Ras protein specific guanine nucleotide releasing factor 1	Homo sapiens	0-8	
10681520-9	2000	Taken together, tyrosine phosphorylation by Src is sufficient for the induction of Rac-GEF activity of Ras-GRF1, which may imply the involvement of Src downstream of Gbetagamma to regulate Ras-GRF1.	Tyrosine	16-24	Ras protein specific guanine nucleotide releasing factor 1	Homo sapiens	103-111	
10681520-9	2000	Taken together, tyrosine phosphorylation by Src is sufficient for the induction of Rac-GEF activity of Ras-GRF1, which may imply the involvement of Src downstream of Gbetagamma to regulate Ras-GRF1.	Tyrosine	16-24	Ras protein specific guanine nucleotide releasing factor 1	Homo sapiens	189-197