PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10649448-4 2000 Treatment of human bone marrow stromal cells with dexamethasone induced the differentiation of these cells into adipocytes as measured by oil-red O staining, and Northern blot analysis showed that dexamethasone strongly induced PPARgamma2 mRNA expression in cells cultured in adipocyte induction medium. Dexamethasone 50-63 peroxisome proliferator activated receptor gamma Mus musculus 228-238 10649448-4 2000 Treatment of human bone marrow stromal cells with dexamethasone induced the differentiation of these cells into adipocytes as measured by oil-red O staining, and Northern blot analysis showed that dexamethasone strongly induced PPARgamma2 mRNA expression in cells cultured in adipocyte induction medium. Dexamethasone 197-210 peroxisome proliferator activated receptor gamma Mus musculus 228-238 10649448-7 2000 Transfection studies in mouse mesenchymal C3H10T1/2 cells showed that it is the tandem repeat of the C/EBP binding site in PPARgamma2 promoter region that regulates dexamethasone-mediated PPARgamma2 gene activation. Dexamethasone 165-178 peroxisome proliferator activated receptor gamma Mus musculus 123-133 10649448-7 2000 Transfection studies in mouse mesenchymal C3H10T1/2 cells showed that it is the tandem repeat of the C/EBP binding site in PPARgamma2 promoter region that regulates dexamethasone-mediated PPARgamma2 gene activation. Dexamethasone 165-178 peroxisome proliferator activated receptor gamma Mus musculus 188-198 10649448-8 2000 We conclude that glucocorticoid-induced adipogenesis from bone marrow stromal cells is mediated through a reaction cascade in which dexamethasone transcriptionally activates C/EBPdelta; C/EBPdelta then binds to PPARgamma2 promoter and transactivates PPARgamma2 gene expression. Dexamethasone 132-145 peroxisome proliferator activated receptor gamma Mus musculus 211-221 10649448-8 2000 We conclude that glucocorticoid-induced adipogenesis from bone marrow stromal cells is mediated through a reaction cascade in which dexamethasone transcriptionally activates C/EBPdelta; C/EBPdelta then binds to PPARgamma2 promoter and transactivates PPARgamma2 gene expression. Dexamethasone 132-145 peroxisome proliferator activated receptor gamma Mus musculus 250-260