PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10620363-0 2000 Disulfide bonds in big ET-1 are essential for the specific cleavage at the Trp(21)-Val(22) bond by soluble endothelin converting enzyme-1 from baculovirus/insect cells. Disulfides 0-9 endothelin converting enzyme 1 Homo sapiens 107-137 10620363-8 2000 This result indicates that secondary/tertiary structure of big ET-1 induced by disulfide bonds is essential for the specific cleavage of the Trp(21)-Val(22) bond by ECE-1. Disulfides 79-88 endothelin converting enzyme 1 Homo sapiens 165-170