PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10516933-4 1999 The objective of this review is to discuss the effects of P-gp modulation on the pharmacokinetics and the pharmacodynamics of immunosuppressive agents such as cyclosporine, tacrolimus, sirolimus, and corticosteroids. Sirolimus 185-194 ATP binding cassette subfamily B member 1 Homo sapiens 58-62