PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10509562-1 1999 OBJECTIVES: To determine the effect of the protease inhibitors ritonavir, nelfinavir and indinavir on the P-glycoprotein (P-gp)-mediated transport of saquinavir in Caco-2 cell monolayers. Nelfinavir 74-84 ATP binding cassette subfamily B member 1 Homo sapiens 106-120 10509562-1 1999 OBJECTIVES: To determine the effect of the protease inhibitors ritonavir, nelfinavir and indinavir on the P-glycoprotein (P-gp)-mediated transport of saquinavir in Caco-2 cell monolayers. Nelfinavir 74-84 ATP binding cassette subfamily B member 1 Homo sapiens 122-126 10509562-2 1999 To study the modulation of P-gp function in human lymphocytes by saquinavir, ritonavir, nelfinavir and indinavir. Nelfinavir 88-98 ATP binding cassette subfamily B member 1 Homo sapiens 27-31 10509562-14 1999 CONCLUSIONS: We have demonstrated that saquinavir is a substrate for P-gp and that ritonavir, nelfinavir and indinavir modulate P-gp function in both human lymphocytes and Caco-2 cells. Nelfinavir 94-104 ATP binding cassette subfamily B member 1 Homo sapiens 128-132