PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10493518-1 1999 Flavopiridol is a novel flavonoid that induces cell cycle arrest at different stages of the cell cycle because of the inhibition of cyclin-dependent kinases (cdks). alvocidib 0-12 cyclin dependent kinase 2 Homo sapiens 158-162 10493518-3 1999 A. Carlson et al., Cancer Res., 56: 2973-2978, 1996), we observed that exposure of the MCF-7 breast carcinoma cell line to flavopiridol resulted in G1-S arrest, which was associated with the loss of cdk4 and cdk2 activity by 24 h of exposure. alvocidib 123-135 cyclin dependent kinase 2 Homo sapiens 208-212