PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10432321-7 1999 Regarding the JAK/STAT pathway, AGE (100 microgram/ml) induced tyrosine phosphorylation of JAK2 (but not JAK1, JAK3 or TYK2) at 15-60 min; it also induced the tyrosine phosphorylation of STAT1 and STAT3 at 1-2 h and 0.5-4 h respectively. Tyrosine 63-71 Janus kinase 2 Rattus norvegicus 91-95 10432321-7 1999 Regarding the JAK/STAT pathway, AGE (100 microgram/ml) induced tyrosine phosphorylation of JAK2 (but not JAK1, JAK3 or TYK2) at 15-60 min; it also induced the tyrosine phosphorylation of STAT1 and STAT3 at 1-2 h and 0.5-4 h respectively. Tyrosine 159-167 Janus kinase 2 Rattus norvegicus 91-95 10432321-8 1999 Being a transcription factor, AGE also increased the DNA-binding activities of STAT1 and STAT3 AG-490 (a specific JAK2 inhibitor) (5 microM) inhibited tyrosine phosphorylation of JAK2 and the DNA-binding activities of STAT1 and STAT3. Tyrosine 151-159 signal transducer and activator of transcription 1 Rattus norvegicus 79-84 10432321-8 1999 Being a transcription factor, AGE also increased the DNA-binding activities of STAT1 and STAT3 AG-490 (a specific JAK2 inhibitor) (5 microM) inhibited tyrosine phosphorylation of JAK2 and the DNA-binding activities of STAT1 and STAT3. Tyrosine 151-159 signal transducer and activator of transcription 3 Rattus norvegicus 89-94 10432321-8 1999 Being a transcription factor, AGE also increased the DNA-binding activities of STAT1 and STAT3 AG-490 (a specific JAK2 inhibitor) (5 microM) inhibited tyrosine phosphorylation of JAK2 and the DNA-binding activities of STAT1 and STAT3. Tyrosine 151-159 Janus kinase 2 Rattus norvegicus 114-118 10432321-10 1999 Meanwhile, the STAT1 or STAT3 decoy ODN and AG-490 were effective in reversing AGE-induced cellular mitogenesis. alpha-cyano-(3,4-dihydroxy)-N-benzylcinnamide 44-50 signal transducer and activator of transcription 3 Rattus norvegicus 24-29