PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10233205-11 1999 CONCLUSIONS: The N-demethylation of methadone in human liver microsomes is not markedly stereoselective, and is mediated mainly by CYP3A4 with the possible involvement of CYP2C9 and CYP2C19. Methadone 36-45 cytochrome P450 family 2 subfamily C member 19 Homo sapiens 182-189