PMID-sentid Pub_year Sent_text comp_official_name comp_offsetprotein_name organism prot_offset 10202848-1 1999 Inhibition of angiotensin (Ang) II type 1 (AT1) receptors in various target tissues of adult Sprague-Dawley rats was studied after single oral administration of TCV-116. candesartan cilexetil 161-168 angiotensin II receptor, type 1a Rattus norvegicus 43-46 10202848-3 1999 Four hours after the administration of TCV-116 (1 mg/kg), Ang II-receptor binding was markedly inhibited in the kidney (20% of control), adrenal cortex (27%), thoracic aorta (57%), heart (55%) and testis (76%) where AT1 receptors predominate. candesartan cilexetil 39-46 angiotensin II receptor, type 1a Rattus norvegicus 216-219 10202848-7 1999 These data indicate that orally administered TCV-116 specifically binds to AT1 receptors both in peripheral tissues and the central nervous system. candesartan cilexetil 45-52 angiotensin II receptor, type 1a Rattus norvegicus 75-78