PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 32035254-4 2020 The self-assembly of STC with Soluplus to load FLDP and the microstructure of the SHNPs were confirmed using molecular simulation, STC determination by HPLC and transmission electron microscope. polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 30-38 stanniocalcin 1 Homo sapiens 21-24 32035254-4 2020 The self-assembly of STC with Soluplus to load FLDP and the microstructure of the SHNPs were confirmed using molecular simulation, STC determination by HPLC and transmission electron microscope. polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 30-38 stanniocalcin 1 Homo sapiens 131-134 32035254-5 2020 Results showed that STC was integrated with Soluplus on the surface of nanoparticles by hydrophobic interactions. polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 44-52 stanniocalcin 1 Homo sapiens 20-23 32035254-6 2020 The permeability of FLDP loaded STC/Soluplus SHNPs was STC dependent in the ileum, which was inhibited by the higher concentrations of STC and the inhibitor of apical sodium-dependent bile acid transporter (ASBT). polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 36-44 stanniocalcin 1 Homo sapiens 55-58 32035254-6 2020 The permeability of FLDP loaded STC/Soluplus SHNPs was STC dependent in the ileum, which was inhibited by the higher concentrations of STC and the inhibitor of apical sodium-dependent bile acid transporter (ASBT). polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 36-44 stanniocalcin 1 Homo sapiens 55-58 32035254-6 2020 The permeability of FLDP loaded STC/Soluplus SHNPs was STC dependent in the ileum, which was inhibited by the higher concentrations of STC and the inhibitor of apical sodium-dependent bile acid transporter (ASBT). polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 36-44 solute carrier family 10 member 2 Homo sapiens 160-205 32035254-6 2020 The permeability of FLDP loaded STC/Soluplus SHNPs was STC dependent in the ileum, which was inhibited by the higher concentrations of STC and the inhibitor of apical sodium-dependent bile acid transporter (ASBT). polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 36-44 solute carrier family 10 member 2 Homo sapiens 207-211 32035254-7 2020 STC/Soluplus (1:9) SHNPs significantly improved the drug loading of FLDP, achieved the highest permeability of FLDP and realized 1.6-fold of the area under the curve (AUC) of Soluplus self-assembled nanoparticles (SNPs). polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 4-12 stanniocalcin 1 Homo sapiens 0-3 32035254-7 2020 STC/Soluplus (1:9) SHNPs significantly improved the drug loading of FLDP, achieved the highest permeability of FLDP and realized 1.6-fold of the area under the curve (AUC) of Soluplus self-assembled nanoparticles (SNPs). polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 175-183 stanniocalcin 1 Homo sapiens 0-3 32035254-9 2020 In conclusion, STC/Soluplus SHNPs via ASBT are a potential strategy for enhancing the oral bioavailability of poorly water-soluble drugs. polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 19-27 stanniocalcin 1 Homo sapiens 15-18 32035254-9 2020 In conclusion, STC/Soluplus SHNPs via ASBT are a potential strategy for enhancing the oral bioavailability of poorly water-soluble drugs. polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 19-27 solute carrier family 10 member 2 Homo sapiens 38-42 27208440-5 2016 Cellular uptake efficiency of HACE/SP NC was higher than that of SP NC, mainly based on HA-CD44 receptor interaction, in MDA-MB-231 (CD44 receptor-positive human breast cancer) cells. polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 35-37 CD44 molecule (Indian blood group) Homo sapiens 91-95 27208440-5 2016 Cellular uptake efficiency of HACE/SP NC was higher than that of SP NC, mainly based on HA-CD44 receptor interaction, in MDA-MB-231 (CD44 receptor-positive human breast cancer) cells. polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 35-37 CD44 molecule (Indian blood group) Homo sapiens 133-137 27208440-8 2016 Given that these experimental results, developed HACE/SP NC can be a promising theranostic nanosystem for CD44 receptor-expressed cancers. polyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymer 54-56 CD44 molecule (Indian blood group) Homo sapiens 106-110