PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 31688897-12 2020 Moreover, we found significant associations between CDAD group and metabolic syndrome, prior use of antibiotic in the last 3 months, NAFLD and high serum levels of C-reactive protein. cdad 52-56 C-reactive protein Homo sapiens 164-182 15871884-11 2005 Albumin level was another major risk factor for CDAD, with an overwhelming 68% of CDAD patients having albumin levels below 3 g/dL (mean 2.68 g/dL) compared with a mean of 3.22 g/dL in the control group (t = 4.210; df = 51; P < .001). cdad 48-52 albumin Homo sapiens 0-7 15871884-11 2005 Albumin level was another major risk factor for CDAD, with an overwhelming 68% of CDAD patients having albumin levels below 3 g/dL (mean 2.68 g/dL) compared with a mean of 3.22 g/dL in the control group (t = 4.210; df = 51; P < .001). cdad 48-52 albumin Homo sapiens 103-110 15871884-11 2005 Albumin level was another major risk factor for CDAD, with an overwhelming 68% of CDAD patients having albumin levels below 3 g/dL (mean 2.68 g/dL) compared with a mean of 3.22 g/dL in the control group (t = 4.210; df = 51; P < .001). cdad 82-86 albumin Homo sapiens 0-7 15871884-11 2005 Albumin level was another major risk factor for CDAD, with an overwhelming 68% of CDAD patients having albumin levels below 3 g/dL (mean 2.68 g/dL) compared with a mean of 3.22 g/dL in the control group (t = 4.210; df = 51; P < .001). cdad 82-86 albumin Homo sapiens 103-110 34452896-3 2021 OBJECTIVE: To determine the role of the serum albumin to creatinine ratio (sACR) in predicting the 30-day all-cause mortality of patients with CDAD in comparison with other known severity scores of CDAD. cdad 143-147 albumin Homo sapiens 40-53 27091869-7 2016 The incidence of CDAD was 3%, 1.3%, and 1.2% in patients who received a PPI, H2RA, and no AST, respectively (4/142 vs 1/70 vs 1/80; OR for PPI vs H2RA = 1.92; 95% CI = 0.21-17.47). cdad 17-21 solute carrier family 17 member 5 Homo sapiens 90-93 28764868-6 2017 As a use case, we compare the efficacy of lanthionine synthetase C-like 2 (LANCL2), a novel immunoregulatory target with promising efficacy in inflammatory bowel disease (IBD), activation with antibiotics, fecal microbiome transplantation and anti-toxin antibodies in the treatment of CDAD. cdad 285-289 LanC (bacterial lantibiotic synthetase component C)-like 2 Mus musculus 75-81 20398664-4 2010 In the present study, we hypothesize that TcdA and TcdB trigger inflammasome-dependent interleukin (IL)-1beta production, which contributes to the pathogenesis of CDAD. cdad 163-167 interleukin 1 beta Mus musculus 87-109 22944235-12 2012 According to multivariate analyses, the predictors of CDAD included prior hospitalization (P < 0.01, OR = 0.002), CRP(P = 0.008, OR = 3.465), NSAID (P = 0.015, OR = 13.950) and WBC (P = 0.003, OR = 8.063). cdad 54-58 C-reactive protein Homo sapiens 117-120 22944235-13 2012 CONCLUSION: The administration of NSAID, elevated CRP and abnormal WBC are significantly associated with CDAD. cdad 105-109 C-reactive protein Homo sapiens 50-53 21449161-5 2011 It seems to be the first report of the association of MTX treatment with CDAD. cdad 73-77 metaxin 1 Homo sapiens 54-57 18067688-9 2008 RESULTS: The evidence for an association between fluoroquinolone use and CDAD, especially CDAD due to the hypervirulent NAP1 strain or the polymerase chain reaction ribotype 027, is becoming stronger. cdad 73-77 nucleosome assembly protein 1 like 1 Homo sapiens 120-124 20435915-3 2010 Thuricin CD is produced by Bacillus thuringiensis DPC 6431, a bacterial strain isolated from a human fecal sample, and it consists of two distinct peptides, Trn-alpha and Trn-beta, that act synergistically to kill a wide range of clinical C. difficile isolates, including ribotypes commonly associated with CDAD (e.g., ribotype 027). cdad 307-311 mitochondrially encoded tRNA glycine Homo sapiens 157-166 18067688-9 2008 RESULTS: The evidence for an association between fluoroquinolone use and CDAD, especially CDAD due to the hypervirulent NAP1 strain or the polymerase chain reaction ribotype 027, is becoming stronger. cdad 90-94 nucleosome assembly protein 1 like 1 Homo sapiens 120-124 17072575-5 2006 Administration of interleukin-2 either during hospitalization or in the 30 days preceding admission was seven times more likely to have occurred in CDAD cases (p = 0.04), raising the question of whether or not this agent increases risk. cdad 148-152 interleukin 2 Homo sapiens 18-31