PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
34070680-0	2021	Urolithin and Reduced Urolithin Derivatives as Potent Inhibitors of Tyrosinase and Melanogenesis: Importance of the 4-Substituted Resorcinol Moiety.	urolithin	0-9	tyrosinase	Homo sapiens	68-78
35142569-2	2022	Urolithin has beneficially biological effects, it can induce adipocyte browning, improve cholesterol metabolism, inhibit graft tumor growth, relieve inflammation, and downregulate neuronal amyloid protein formation via the beta3-AR/PKA/p38MAPK, ERK/AMPKalpha/SREBP1, PI3K/AKT/mTOR signaling pathways, and TLR4, AHR receptors.	urolithin	0-9	adenosine A3 receptor	Homo sapiens	223-235
35142569-2	2022	Urolithin has beneficially biological effects, it can induce adipocyte browning, improve cholesterol metabolism, inhibit graft tumor growth, relieve inflammation, and downregulate neuronal amyloid protein formation via the beta3-AR/PKA/p38MAPK, ERK/AMPKalpha/SREBP1, PI3K/AKT/mTOR signaling pathways, and TLR4, AHR receptors.	urolithin	0-9	mitogen-activated protein kinase 1	Homo sapiens	245-248
35142569-2	2022	Urolithin has beneficially biological effects, it can induce adipocyte browning, improve cholesterol metabolism, inhibit graft tumor growth, relieve inflammation, and downregulate neuronal amyloid protein formation via the beta3-AR/PKA/p38MAPK, ERK/AMPKalpha/SREBP1, PI3K/AKT/mTOR signaling pathways, and TLR4, AHR receptors.	urolithin	0-9	sterol regulatory element binding transcription factor 1	Homo sapiens	259-265
35142569-2	2022	Urolithin has beneficially biological effects, it can induce adipocyte browning, improve cholesterol metabolism, inhibit graft tumor growth, relieve inflammation, and downregulate neuronal amyloid protein formation via the beta3-AR/PKA/p38MAPK, ERK/AMPKalpha/SREBP1, PI3K/AKT/mTOR signaling pathways, and TLR4, AHR receptors.	urolithin	0-9	AKT serine/threonine kinase 1	Homo sapiens	272-275
35142569-2	2022	Urolithin has beneficially biological effects, it can induce adipocyte browning, improve cholesterol metabolism, inhibit graft tumor growth, relieve inflammation, and downregulate neuronal amyloid protein formation via the beta3-AR/PKA/p38MAPK, ERK/AMPKalpha/SREBP1, PI3K/AKT/mTOR signaling pathways, and TLR4, AHR receptors.	urolithin	0-9	mechanistic target of rapamycin kinase	Homo sapiens	276-280
35142569-2	2022	Urolithin has beneficially biological effects, it can induce adipocyte browning, improve cholesterol metabolism, inhibit graft tumor growth, relieve inflammation, and downregulate neuronal amyloid protein formation via the beta3-AR/PKA/p38MAPK, ERK/AMPKalpha/SREBP1, PI3K/AKT/mTOR signaling pathways, and TLR4, AHR receptors.	urolithin	0-9	toll like receptor 4	Homo sapiens	305-309
35142569-2	2022	Urolithin has beneficially biological effects, it can induce adipocyte browning, improve cholesterol metabolism, inhibit graft tumor growth, relieve inflammation, and downregulate neuronal amyloid protein formation via the beta3-AR/PKA/p38MAPK, ERK/AMPKalpha/SREBP1, PI3K/AKT/mTOR signaling pathways, and TLR4, AHR receptors.	urolithin	0-9	aryl hydrocarbon receptor	Homo sapiens	311-314
28283501-7	2017	The aim of this study was to isolate and structurally characterize urolithin conjugates from the urine of a volunteer who ingested ellagitannin-rich natural products, and to evaluate the potential role of beta-glucuronidase-triggered cleavage in urolithin disposition.	urolithin	67-76	glucuronidase beta	Homo sapiens	205-223
28283501-7	2017	The aim of this study was to isolate and structurally characterize urolithin conjugates from the urine of a volunteer who ingested ellagitannin-rich natural products, and to evaluate the potential role of beta-glucuronidase-triggered cleavage in urolithin disposition.	urolithin	246-255	glucuronidase beta	Homo sapiens	205-223