PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
2783301-2	1989	The WT1-SMPT-dgRTA conjugate was cytotoxic to CEM (T-lymphoblastic leukemia) cells in vitro with an ID50 of 53 pM.	2-chloroethyl methyl sulfide	46-49	WT1 transcription factor	Homo sapiens	4-7
2784323-6	1989	More than 6-logs of CEM appeared to be eliminated after incubation with 10(-8) M WT1-ricin A. Immunotoxins are only effective after entering the target cell.	2-chloroethyl methyl sulfide	20-23	WT1 transcription factor	Homo sapiens	81-84
34015673-6	2021	RESULTS: Significant effects of CEM were found in two subregions of the left hippocampus, the CA1 (df = 95; q = 0.003) and the strata radiatum/lacunosum/moleculare (df = 95; q = 0.003).	2-chloroethyl methyl sulfide	32-35	carbonic anhydrase 1	Homo sapiens	94-97
3259875-1	1988	A subclone, designated CEM-ON, derived from an azaguanine-resistant human leukemic T cell line, CEM-AG(R), constitutively secretes a colony-stimulating factor (CSF) which stimulates the production of macrophages from murine bone marrow progenitor cells.	2-chloroethyl methyl sulfide	23-26	colony stimulating factor 2	Homo sapiens	160-163
3259875-5	1988	On SDS-PAGE analysis, CEM-ON CSF had an apparent molecular weight of 33,000-43,000; following reduction with 2-mercaptoethanol, this migrated as a 20,000-24,000 subunit, suggesting a homodimer structure.	2-chloroethyl methyl sulfide	22-25	colony stimulating factor 2	Homo sapiens	29-32
6272978-2	1981	One mutant that lacked deoxycytidine kinase activity, designated CEM/ara-C, retained about 10% of wild-type deoxyadenosine kinase and deoxyguanosine kinase activity each but maintained normal adenosine kinase or thymidine kinase activity.	2-chloroethyl methyl sulfide	65-68	deoxycytidine kinase	Homo sapiens	23-43
6272978-2	1981	One mutant that lacked deoxycytidine kinase activity, designated CEM/ara-C, retained about 10% of wild-type deoxyadenosine kinase and deoxyguanosine kinase activity each but maintained normal adenosine kinase or thymidine kinase activity.	2-chloroethyl methyl sulfide	65-68	adenosine kinase	Homo sapiens	113-129
3261775-5	1988	One nonpermissive, CD4+ derivative of CEM could bind gp120 but failed to undergo fusion, suggesting an alteration in some membrane protein other than CD4 that is essential for virus entry and HIV-induced cell fusion.	2-chloroethyl methyl sulfide	38-41	CD4 molecule	Homo sapiens	19-22
3261775-5	1988	One nonpermissive, CD4+ derivative of CEM could bind gp120 but failed to undergo fusion, suggesting an alteration in some membrane protein other than CD4 that is essential for virus entry and HIV-induced cell fusion.	2-chloroethyl methyl sulfide	38-41	inter-alpha-trypsin inhibitor heavy chain 4	Homo sapiens	53-58
3871222-2	1985	The NK susceptibility of the resulting subline, CEM.NKR, was 8.4 to 20.6% of that of CEM when PBMC or adherent cell-depleted PBMC were used as effector cells, and -7.1 to 12.1% of that of CEM when Percoll gradient-enriched large granular lymphocytes (LGL) were used.	2-chloroethyl methyl sulfide	48-51	killer cell lectin like receptor B1	Homo sapiens	52-55
3871222-4	1985	Unlabeled CEM was eight- to 32-fold more effective than unlabeled CEM.NKR in inhibiting the NK lysis of labeled CEM target cells, and CEM bound 1.9 to 3.9-fold more Percoll gradient-enriched LGL than CEM.NKR in single cell-binding assays, suggesting that the NK-resistant variant has lost the expression of NK target antigens.	2-chloroethyl methyl sulfide	10-13	killer cell lectin like receptor B1	Homo sapiens	70-73
3871222-4	1985	Unlabeled CEM was eight- to 32-fold more effective than unlabeled CEM.NKR in inhibiting the NK lysis of labeled CEM target cells, and CEM bound 1.9 to 3.9-fold more Percoll gradient-enriched LGL than CEM.NKR in single cell-binding assays, suggesting that the NK-resistant variant has lost the expression of NK target antigens.	2-chloroethyl methyl sulfide	66-69	killer cell lectin like receptor B1	Homo sapiens	70-73
6225514-4	1983	Assay of cellular dihydrofolate reductase (DHFR) showed the following pattern of activity in resistant cell lines, relative to parental cell activity: RAJI/MTX-R, 550-fold increased; CEM/MTX-R, unchanged; TE-85/MTX-R, 4-fold increased; MG-63/MTX-R, 6-fold increased; SAOS-2/MTX-R, unchanged; and WI-L2/m4, 110-fold increased.	2-chloroethyl methyl sulfide	183-186	dihydrofolate reductase	Homo sapiens	18-41
6225514-4	1983	Assay of cellular dihydrofolate reductase (DHFR) showed the following pattern of activity in resistant cell lines, relative to parental cell activity: RAJI/MTX-R, 550-fold increased; CEM/MTX-R, unchanged; TE-85/MTX-R, 4-fold increased; MG-63/MTX-R, 6-fold increased; SAOS-2/MTX-R, unchanged; and WI-L2/m4, 110-fold increased.	2-chloroethyl methyl sulfide	183-186	dihydrofolate reductase	Homo sapiens	43-47
6281270-0	1982	Effects of mutational loss of adenosine kinase and deoxycytidine kinase on deoxyATP accumulation and deoxyadenosine toxicity in cultured CEM human T-lymphoblastoid cells.	2-chloroethyl methyl sulfide	137-140	adenosine kinase	Homo sapiens	30-46
6276438-6	1982	In addition, CEM were protected from cytolysis by the effector cells by the myeloperoxidase inhibitors, azide and cyanide, or by performing the experiment under halide-free conditions.	2-chloroethyl methyl sulfide	13-16	myeloperoxidase	Homo sapiens	76-91
6276438-8	1982	Hypochlorous acid scavengers prevented CEM destruction by the glucose oxidase-myeloperoxidase-chloride system but neither hydroxyl radical nor singlet oxygen scavengers had any protective effect.	2-chloroethyl methyl sulfide	39-42	myeloperoxidase	Homo sapiens	78-93
6276438-10	1982	Based on these observations we propose that human monocytes or granulocytes can utilize the hydrogen peroxide-myeloperoxidase-chloride system to generate hypochlorous acid or species of similar reactivity as a potential mediator of CEM destruction.	2-chloroethyl methyl sulfide	232-235	myeloperoxidase	Homo sapiens	110-125
19928057-2	2009	We had previously shown in vitro using human acute leukemia cells with various sensitivity to MTX (T-lymphoblastic CCRF-CEM line and resistant CEM/MTX subline) that MTX incorporation into liposomes as a lipophilic prodrug, diglyceride conjugate (MTX-DG), allows for the overcoming of cell resistance due to the impaired active transmembrane transport.	2-chloroethyl methyl sulfide	120-123	metaxin 1	Homo sapiens	94-97
22528119-9	2012	We further confirmed that Top2alpha inhibition was due to a catalytic inhibition of the enzyme because it did not induce DNA double-strand breaks in CEM-treated cells but prevented the formation of Top2alpha- rather than Top2beta-DNA covalent complexes induced by etoposide.	2-chloroethyl methyl sulfide	149-152	DNA topoisomerase II alpha	Homo sapiens	26-35
21290089-10	2011	Both proteome and DNA microarray analyses further detected a reduced protein level of stathmin1 in the ara-C-resistant CEM subclone compared to its parental line.	2-chloroethyl methyl sulfide	119-122	stathmin 1	Homo sapiens	86-95
25058613-5	2014	Here, we show that ceramide-enriched-CEMs are markedly more abundant in L6 myotubes compared to C2C12 myotubes, consistent with their previously reported role in coordinating aPKC-directed repression of PKB/Akt in L6 muscle cells.	2-chloroethyl methyl sulfide	37-41	AKT serine/threonine kinase 1	Homo sapiens	203-210
22117551-5	2011	In this work we have investigated effects of a promising new selective GR agonist, 2-(4-acetoxyphenyl)-2-chloro-N-methylethylammonium chloride (CpdA), on CEM and K562 leukemia cells.	2-chloroethyl methyl sulfide	154-157	nuclear receptor subfamily 3 group C member 1	Homo sapiens	71-73
19928057-6	2009	The activity of MTX liposomes bearing 6"-HSO3LacNAc toward resistant CEM/MTX was 1.6-fold increased.	2-chloroethyl methyl sulfide	69-72	metaxin 1	Homo sapiens	16-19
19928057-6	2009	The activity of MTX liposomes bearing 6"-HSO3LacNAc toward resistant CEM/MTX was 1.6-fold increased.	2-chloroethyl methyl sulfide	69-72	metaxin 1	Homo sapiens	73-76
19505399-8	2009	Stimulation of CEM with 10 microg/ml of phytohemagglutinin (PHA) for 16 h upregulated expression of the alpha3, alpha5, alpha7, alpha9 and beta2 and downregulated that of alpha6 and beta4 subunits, indicating that TCR activation leads to overexpression of high Ca2+-permeable ACh-gated ion channels.	2-chloroethyl methyl sulfide	15-18	potassium calcium-activated channel subfamily M regulatory beta subunit 2	Homo sapiens	139-144
19002102-2	2008	Here, we studied the expression of one influx transporter system, human organic anion-transporting polypeptide (hOATP), in some T-cell lines (CEM, CEM(VBL), CEM(E1000)) and in peripheral blood mononuclear cells (PBMCs) and examined the effects of manipulation of influx/efflux transporters on the uptake of saquinavir and lopinavir.	2-chloroethyl methyl sulfide	142-145	solute carrier organic anion transporter family member 1A2	Homo sapiens	112-117
19002102-2	2008	Here, we studied the expression of one influx transporter system, human organic anion-transporting polypeptide (hOATP), in some T-cell lines (CEM, CEM(VBL), CEM(E1000)) and in peripheral blood mononuclear cells (PBMCs) and examined the effects of manipulation of influx/efflux transporters on the uptake of saquinavir and lopinavir.	2-chloroethyl methyl sulfide	147-150	solute carrier organic anion transporter family member 1A2	Homo sapiens	112-117
19002102-2	2008	Here, we studied the expression of one influx transporter system, human organic anion-transporting polypeptide (hOATP), in some T-cell lines (CEM, CEM(VBL), CEM(E1000)) and in peripheral blood mononuclear cells (PBMCs) and examined the effects of manipulation of influx/efflux transporters on the uptake of saquinavir and lopinavir.	2-chloroethyl methyl sulfide	147-150	solute carrier organic anion transporter family member 1A2	Homo sapiens	112-117
18279955-6	2008	Examination of ImmH cytotoxicity in a hypoxanthine-guanine phosphoribosyltransferase (HGPRT)-deficient cell line CCRF-CEM-AraC-8C, demonstrated enhanced sensitivity to low concentrations of ImmH and dGuo.	2-chloroethyl methyl sulfide	118-122	hypoxanthine phosphoribosyltransferase 1	Homo sapiens	38-84
18990339-8	2008	RESULTS: The caliber of portal vein (Cpv) and Ppv in the CEM group (after 4-week prevention) were significantly decreased as compared with those in the untreated group at the same point of time (P<0.05), also including serum HA content (P<0.05), and vWF, Col I, Col IV, LM, alpha-SMA positive staining (P<0.05); however, CD44 positive staining were increased in the CEM group (P<0.05).	2-chloroethyl methyl sulfide	57-60	von Willebrand factor	Rattus norvegicus	256-259
18990339-8	2008	RESULTS: The caliber of portal vein (Cpv) and Ppv in the CEM group (after 4-week prevention) were significantly decreased as compared with those in the untreated group at the same point of time (P<0.05), also including serum HA content (P<0.05), and vWF, Col I, Col IV, LM, alpha-SMA positive staining (P<0.05); however, CD44 positive staining were increased in the CEM group (P<0.05).	2-chloroethyl methyl sulfide	57-60	actin gamma 2, smooth muscle	Rattus norvegicus	280-289
18990339-8	2008	RESULTS: The caliber of portal vein (Cpv) and Ppv in the CEM group (after 4-week prevention) were significantly decreased as compared with those in the untreated group at the same point of time (P<0.05), also including serum HA content (P<0.05), and vWF, Col I, Col IV, LM, alpha-SMA positive staining (P<0.05); however, CD44 positive staining were increased in the CEM group (P<0.05).	2-chloroethyl methyl sulfide	57-60	CD44 molecule (Indian blood group)	Rattus norvegicus	330-334
16614259-5	2006	Chemotactic responses of CEM and human Th2 cells to CCL17 and CCL22 were similarly abrogated by inhibition of PLC and inhibition of novel, Ca2+-independent/diacylglycerol-dependent protein kinase C (PKC) isoforms.	2-chloroethyl methyl sulfide	25-28	C-C motif chemokine ligand 17	Homo sapiens	52-57
16769721-2	2006	The new glutathione S-transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) is cytotoxic toward P-glycoprotein-overexpressing tumor cell lines, i.e. CEM-VBL10, CEM-VBL100, and U-2 OS/DX580.	2-chloroethyl methyl sulfide	174-177	ATP binding cassette subfamily B member 1	Homo sapiens	121-135
16769721-2	2006	The new glutathione S-transferase inhibitor 6-(7-nitro-2,1,3-benzoxadiazol-4-ylthio)hexanol (NBDHEX) is cytotoxic toward P-glycoprotein-overexpressing tumor cell lines, i.e. CEM-VBL10, CEM-VBL100, and U-2 OS/DX580.	2-chloroethyl methyl sulfide	185-188	ATP binding cassette subfamily B member 1	Homo sapiens	121-135
16614259-5	2006	Chemotactic responses of CEM and human Th2 cells to CCL17 and CCL22 were similarly abrogated by inhibition of PLC and inhibition of novel, Ca2+-independent/diacylglycerol-dependent protein kinase C (PKC) isoforms.	2-chloroethyl methyl sulfide	25-28	C-C motif chemokine ligand 22	Homo sapiens	62-67
11986953-3	2002	Exposure to 4-HPR (12 microM) for 96 h caused 4.7 (MOLT-3), 3.5 (MOLT-4), 3.9 (CEM), 2.9 (NALM-6), 4.7 (SMS-SB), AND 4.5 (NALL-1) logs of cell kill.	2-chloroethyl methyl sulfide	79-82	haptoglobin-related protein	Homo sapiens	14-17
31394621-2	2004	In the present study we treated the Fas-expressed human immature T-cell line CCRF-CEM with 10muM Cd2+ for 6h or 24h.	2-chloroethyl methyl sulfide	82-85	CD2 molecule	Homo sapiens	97-100
11727785-6	2001	A segment of KOR transcript spanning the second extracellular loop, which has the reported dynorphin specificity, and the seventh transmembrane domain of the receptor was amplified from the total RNA of morphine-treated CEM x174 lymphocytes, along with a competitor molecule.	2-chloroethyl methyl sulfide	220-223	opioid receptor kappa 1	Homo sapiens	13-16
11724283-6	2001	Two CEM drug-resistant clones, CEM/ara-C/G/ASNase-0.5-1 and CEM/ara-C/G/ASNase-1-1, lacked VEGF production.	2-chloroethyl methyl sulfide	4-7	asparaginase and isoaspartyl peptidase 1	Homo sapiens	43-49
11042698-8	2000	The activity of p53 on pro-apoptotic genes expression in response to DNA damage induced by (-irradiation, was affected in the vinblastine (VLB) resistant cell line but not in CCRF-CEM sensitive cell line resulting in a much reduced apoptotic cell death of the multi-drug resistant cells.	2-chloroethyl methyl sulfide	180-183	tumor protein p53	Homo sapiens	16-19
10411602-9	1999	The modulator"s effect on Pgp was evaluated with Pgp-overexpressing CEM/vinblastine (VLB)(100) and parental CCRF-CEM cells.	2-chloroethyl methyl sulfide	68-71	ATP binding cassette subfamily B member 1	Homo sapiens	26-29
10871059-4	2000	We found that CEM and CEM.NK(R) cells constitutively synthesized all TCR subunits except for TCRalpha and that CD3gamma,delta,epsilon components and CD3-beta complexes were effectively assembled together in both cell types.	2-chloroethyl methyl sulfide	14-17	CD3 gamma subunit of T-cell receptor complex	Homo sapiens	111-125
10871059-4	2000	We found that CEM and CEM.NK(R) cells constitutively synthesized all TCR subunits except for TCRalpha and that CD3gamma,delta,epsilon components and CD3-beta complexes were effectively assembled together in both cell types.	2-chloroethyl methyl sulfide	22-25	T cell receptor alpha constant	Homo sapiens	93-101
10871059-4	2000	We found that CEM and CEM.NK(R) cells constitutively synthesized all TCR subunits except for TCRalpha and that CD3gamma,delta,epsilon components and CD3-beta complexes were effectively assembled together in both cell types.	2-chloroethyl methyl sulfide	22-25	CD3 gamma subunit of T-cell receptor complex	Homo sapiens	111-125
10769646-13	2000	Three cell lines resistant to ara-C (CEM/ara-C/B, CEM/ara-C/D and CEM/ara-C/I) showed an important increased expression of bcl-2 protein after treatment with 1 microM ara-C, but not after 10 microM.	2-chloroethyl methyl sulfide	37-40	BCL2 apoptosis regulator	Homo sapiens	123-128
10769646-13	2000	Three cell lines resistant to ara-C (CEM/ara-C/B, CEM/ara-C/D and CEM/ara-C/I) showed an important increased expression of bcl-2 protein after treatment with 1 microM ara-C, but not after 10 microM.	2-chloroethyl methyl sulfide	50-53	BCL2 apoptosis regulator	Homo sapiens	123-128
10769646-13	2000	Three cell lines resistant to ara-C (CEM/ara-C/B, CEM/ara-C/D and CEM/ara-C/I) showed an important increased expression of bcl-2 protein after treatment with 1 microM ara-C, but not after 10 microM.	2-chloroethyl methyl sulfide	50-53	BCL2 apoptosis regulator	Homo sapiens	123-128
10769646-17	2000	However, three ara-C resistant cell clones, CEM/ara-C/7A, CEM/ara-C/B and CEM/ara-C/G, were positive for P-gp expression and functional activity.	2-chloroethyl methyl sulfide	44-47	ATP binding cassette subfamily B member 1	Homo sapiens	105-109
10769646-17	2000	However, three ara-C resistant cell clones, CEM/ara-C/7A, CEM/ara-C/B and CEM/ara-C/G, were positive for P-gp expression and functional activity.	2-chloroethyl methyl sulfide	58-61	ATP binding cassette subfamily B member 1	Homo sapiens	105-109
10769646-17	2000	However, three ara-C resistant cell clones, CEM/ara-C/7A, CEM/ara-C/B and CEM/ara-C/G, were positive for P-gp expression and functional activity.	2-chloroethyl methyl sulfide	58-61	ATP binding cassette subfamily B member 1	Homo sapiens	105-109
11042688-3	2000	By pulse-chase experiments, we found that the half-lives of mutant p53 protein were approximately 12, 17, and >30 h in CEM, CEM/VM-1, and CEM/VM-1-5 cells, respectively.	2-chloroethyl methyl sulfide	122-125	tumor protein p53	Homo sapiens	67-70
10411602-9	1999	The modulator"s effect on Pgp was evaluated with Pgp-overexpressing CEM/vinblastine (VLB)(100) and parental CCRF-CEM cells.	2-chloroethyl methyl sulfide	68-71	ATP binding cassette subfamily B member 1	Homo sapiens	49-52
9637506-6	1998	The protein synthesis inhibitor, cycloheximide, increased TNF-induced cPLA2 activity and cytotoxicity in both CEM and CEM/VLB100 cell lines.	2-chloroethyl methyl sulfide	110-113	tumor necrosis factor	Homo sapiens	58-61
9734656-3	1998	CEM induced to overexpress bcl-2, and REH) displayed parallel sensitivity to four antileukaemia drugs with different mechanisms of action, with K562 generally being the least sensitive and REH being the most sensitive.	2-chloroethyl methyl sulfide	0-3	BCL2 apoptosis regulator	Homo sapiens	27-32
9734656-3	1998	CEM induced to overexpress bcl-2, and REH) displayed parallel sensitivity to four antileukaemia drugs with different mechanisms of action, with K562 generally being the least sensitive and REH being the most sensitive.	2-chloroethyl methyl sulfide	0-3	carboxylesterase 1	Homo sapiens	189-192
9704902-4	1998	Addition of heptachlor to human CEM x174 lymphocytic cells reduced the cellular levels of MAP kinase (MAPK, mitogen-activated protein kinase) cascade proteins, including ERK1 (a 44-kDa MAPK), ERK2 (a 42-kDa MAPK), a 85-kDa and a 54-kDa MAP kinase, MEK1 (a 45-kDa ERK kinase) and MEKK (a 78-kDa MEK kinase).	2-chloroethyl methyl sulfide	32-35	mitogen-activated protein kinase 3	Homo sapiens	102-106
9704902-4	1998	Addition of heptachlor to human CEM x174 lymphocytic cells reduced the cellular levels of MAP kinase (MAPK, mitogen-activated protein kinase) cascade proteins, including ERK1 (a 44-kDa MAPK), ERK2 (a 42-kDa MAPK), a 85-kDa and a 54-kDa MAP kinase, MEK1 (a 45-kDa ERK kinase) and MEKK (a 78-kDa MEK kinase).	2-chloroethyl methyl sulfide	32-35	mitogen-activated protein kinase 3	Homo sapiens	170-174
9704902-4	1998	Addition of heptachlor to human CEM x174 lymphocytic cells reduced the cellular levels of MAP kinase (MAPK, mitogen-activated protein kinase) cascade proteins, including ERK1 (a 44-kDa MAPK), ERK2 (a 42-kDa MAPK), a 85-kDa and a 54-kDa MAP kinase, MEK1 (a 45-kDa ERK kinase) and MEKK (a 78-kDa MEK kinase).	2-chloroethyl methyl sulfide	32-35	mitogen-activated protein kinase 3	Homo sapiens	185-189
9704902-4	1998	Addition of heptachlor to human CEM x174 lymphocytic cells reduced the cellular levels of MAP kinase (MAPK, mitogen-activated protein kinase) cascade proteins, including ERK1 (a 44-kDa MAPK), ERK2 (a 42-kDa MAPK), a 85-kDa and a 54-kDa MAP kinase, MEK1 (a 45-kDa ERK kinase) and MEKK (a 78-kDa MEK kinase).	2-chloroethyl methyl sulfide	32-35	mitogen-activated protein kinase 3	Homo sapiens	185-189
7691638-3	1993	The supernatant of CEM (CEM-SUP) increased the expression of both ICAM-1 and ELAM-1 in time- and dose-dependent manners as shown by cell enzyme-linked immunoabsorbent assay (ELISA).	2-chloroethyl methyl sulfide	19-22	intercellular adhesion molecule 1	Homo sapiens	66-72
9032443-2	1997	In culture they show important differences in cholesterol metabolism, CEM being less efficient at synthesizing cholesterol and having a lower activity of 3-hydroxy-3-methylglutaryl-CoA (HMGCoA) reductase.	2-chloroethyl methyl sulfide	70-73	3-hydroxy-3-methylglutaryl-CoA reductase	Homo sapiens	154-203
9562377-5	1998	Incubation of NK cells with CEM but not with the other two lines led to increased expression of the NK cell activation marker CD69.	2-chloroethyl methyl sulfide	28-31	CD69 molecule	Homo sapiens	126-130
8681456-0	1996	Activation of H-ras oncogenes in male B6C3F1 mouse liver tumors induced by vinthionine or 2-chloroethyl-methyl sulfide.	2-chloroethyl methyl sulfide	90-118	Harvey rat sarcoma virus oncogene	Mus musculus	14-19
7903230-2	1994	A purified soluble CEM membrane used as the CD4+ T cell clonotypic model in immunoblotting techniques revealed a homogeneous pattern of IgM-mediated reactivity to a 43.5-kDa membrane component in 10 sera.	2-chloroethyl methyl sulfide	19-22	CD4 molecule	Homo sapiens	44-47
7691638-3	1993	The supernatant of CEM (CEM-SUP) increased the expression of both ICAM-1 and ELAM-1 in time- and dose-dependent manners as shown by cell enzyme-linked immunoabsorbent assay (ELISA).	2-chloroethyl methyl sulfide	19-22	selectin E	Homo sapiens	77-83
2158125-3	1990	We synthesized a series of penta- and tetrapeptide analogs of amino acids 32-36 of human thymopoietin and thysplenin, and now show that distinct patterns of activity can be obtained in these small peptides, with selectivity for cyclic GMP elevation in MOLT-4 alone or CEM alone.	2-chloroethyl methyl sulfide	268-271	thymopoietin	Homo sapiens	89-101
8396937-9	1993	The recombination activating gene, RAG1, which is one of the components of the site-specific V(D)J recombination complex, was 20-fold overexpressed in CEM/DOX cells.	2-chloroethyl methyl sulfide	151-154	recombination activating 1	Homo sapiens	35-39
8396937-15	1993	Since DNA topoisomerases are themselves involved in the control of DNA topology, recombination and DNA repair, the possible coactivation of RAG1 and topoisomerase I genes in CEM/DOX cells is discussed.	2-chloroethyl methyl sulfide	174-177	recombination activating 1	Homo sapiens	140-144
1375534-6	1992	Treatment of CEM-engrafted mice with 4A2-RTA30, an immunoconjugate of an anti-CD7 monoclonal antibody and ricin A chain (RTA30), resulted in a 100- to 200-fold overall depletion of CEM cells from the spleen and the bone marrow (P less than 0.02).	2-chloroethyl methyl sulfide	13-16	CD7 antigen	Mus musculus	78-81
17055708-7	2007	DPPIV activity in culture medium supernatant of CEM versus MOLT3 controls cells (1.91+/-0.43 versus 2.06+/-0.50) and of CEM versus MOLT3 treated cells (2.10+/-0.16 versus 1.89+/-0.04) did not show a significant difference.	2-chloroethyl methyl sulfide	48-51	dipeptidyl peptidase 4	Homo sapiens	0-5