PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
28968948-3	2017	The analysis of Teucrium alopecurus (TA-1) with Gas Chromatography-Mass Spectrometry (GC/MS) showed that alpha-Bisabolol, (+)-epi-Bicyclosesquiphellandrene and alpha-Cadinol, were found in relatively high amounts (16.16%, 15.40% and 8.52%, respectively).	cadinol	160-173	trace amine associated receptor 1	Homo sapiens	37-41
28991393-5	2018	In particularly, peak 1 (alpha-pipene), peak 3 (beta-pinene), peak 9 (camphor) and peak 16 (alpha-cadinol) might be the main bioactive ingredients for analgesic and anti-inflammatory activities.	cadinol	92-105	pseudopodium-enriched atypical kinase 1	Mus musculus	17-23
21699244-2	2011	The results revealed that post-treatment with 100 mumol/kg trans-cinnamaldehyde, (-)-aromadendrene, T-cadinol, or alpha-cadinol significantly decreased the aspartate aminotransferase (AST), alanine aminotransferase (ALT), tumor necrosis factor-alpha (TNF-alpha), and interleukin 6 (IL-6) levels in serum.	cadinol	114-127	solute carrier family 17 (anion/sugar transporter), member 5	Mus musculus	156-182
28947153-5	2017	alpha-Cadinol (2) was found to inhibit the activation of Akt/mTOR pathway, and the hyperactivation of autophagy leading to preferential PANC-1 cell death during nutrient-starvation.	cadinol	0-13	AKT serine/threonine kinase 1	Homo sapiens	57-60
28947153-5	2017	alpha-Cadinol (2) was found to inhibit the activation of Akt/mTOR pathway, and the hyperactivation of autophagy leading to preferential PANC-1 cell death during nutrient-starvation.	cadinol	0-13	mechanistic target of rapamycin kinase	Homo sapiens	61-65
21699244-2	2011	The results revealed that post-treatment with 100 mumol/kg trans-cinnamaldehyde, (-)-aromadendrene, T-cadinol, or alpha-cadinol significantly decreased the aspartate aminotransferase (AST), alanine aminotransferase (ALT), tumor necrosis factor-alpha (TNF-alpha), and interleukin 6 (IL-6) levels in serum.	cadinol	114-127	solute carrier family 17 (anion/sugar transporter), member 5	Mus musculus	184-187
21699244-2	2011	The results revealed that post-treatment with 100 mumol/kg trans-cinnamaldehyde, (-)-aromadendrene, T-cadinol, or alpha-cadinol significantly decreased the aspartate aminotransferase (AST), alanine aminotransferase (ALT), tumor necrosis factor-alpha (TNF-alpha), and interleukin 6 (IL-6) levels in serum.	cadinol	114-127	glutamic pyruvic transaminase, soluble	Mus musculus	190-214
21699244-2	2011	The results revealed that post-treatment with 100 mumol/kg trans-cinnamaldehyde, (-)-aromadendrene, T-cadinol, or alpha-cadinol significantly decreased the aspartate aminotransferase (AST), alanine aminotransferase (ALT), tumor necrosis factor-alpha (TNF-alpha), and interleukin 6 (IL-6) levels in serum.	cadinol	114-127	glutamic pyruvic transaminase, soluble	Mus musculus	216-219
21699244-2	2011	The results revealed that post-treatment with 100 mumol/kg trans-cinnamaldehyde, (-)-aromadendrene, T-cadinol, or alpha-cadinol significantly decreased the aspartate aminotransferase (AST), alanine aminotransferase (ALT), tumor necrosis factor-alpha (TNF-alpha), and interleukin 6 (IL-6) levels in serum.	cadinol	114-127	tumor necrosis factor	Mus musculus	222-249
21699244-2	2011	The results revealed that post-treatment with 100 mumol/kg trans-cinnamaldehyde, (-)-aromadendrene, T-cadinol, or alpha-cadinol significantly decreased the aspartate aminotransferase (AST), alanine aminotransferase (ALT), tumor necrosis factor-alpha (TNF-alpha), and interleukin 6 (IL-6) levels in serum.	cadinol	114-127	tumor necrosis factor	Mus musculus	251-260
21699244-2	2011	The results revealed that post-treatment with 100 mumol/kg trans-cinnamaldehyde, (-)-aromadendrene, T-cadinol, or alpha-cadinol significantly decreased the aspartate aminotransferase (AST), alanine aminotransferase (ALT), tumor necrosis factor-alpha (TNF-alpha), and interleukin 6 (IL-6) levels in serum.	cadinol	114-127	interleukin 6	Mus musculus	267-280
21699244-2	2011	The results revealed that post-treatment with 100 mumol/kg trans-cinnamaldehyde, (-)-aromadendrene, T-cadinol, or alpha-cadinol significantly decreased the aspartate aminotransferase (AST), alanine aminotransferase (ALT), tumor necrosis factor-alpha (TNF-alpha), and interleukin 6 (IL-6) levels in serum.	cadinol	114-127	interleukin 6	Mus musculus	282-286
21699244-3	2011	Moreover, both T-cadinol and alpha-cadinol treatments decreased the expressions of cleaved caspase-3 and cleaved poly-ADP ribose polymerase (PARP) in the liver tissues when compared with the LPS/D-GalN group.	cadinol	29-42	poly (ADP-ribose) polymerase family, member 1	Mus musculus	113-139
21699244-3	2011	Moreover, both T-cadinol and alpha-cadinol treatments decreased the expressions of cleaved caspase-3 and cleaved poly-ADP ribose polymerase (PARP) in the liver tissues when compared with the LPS/D-GalN group.	cadinol	29-42	poly (ADP-ribose) polymerase family, member 1	Mus musculus	141-145
21699244-3	2011	Moreover, both T-cadinol and alpha-cadinol treatments decreased the expressions of cleaved caspase-3 and cleaved poly-ADP ribose polymerase (PARP) in the liver tissues when compared with the LPS/D-GalN group.	cadinol	29-42	galanin and GMAP prepropeptide	Mus musculus	197-201
21699244-4	2011	Liver histopathology also showed that silymarin, trans-cinnamaldehyde, (-)-aromadendrene, T-cadinol, or alpha-cadinol significantly reduced the incidence of liver lesions induced by LPS/D-GalN.	cadinol	104-117	galanin and GMAP prepropeptide	Mus musculus	188-192
16631732-8	2006	Naive T cells co-cultured with allogeneic T-cadinol-primed dendritic cells or calamenene-primed dendritic cells at 1:5 dendritic cells/T cell ratio turned into typical Th1 cells which produced large quantities of interferon-gamma (IFN-gamma) and released small amounts of IL-4 depending on IL-12 secretion.	cadinol	44-51	negative elongation factor complex member C/D	Homo sapiens	168-171
16631732-10	2006	T-cadinol-primed dendritic cells and calamenene-primed dendritic cells expressed the chemokine receptor CCR7 and had a high migration to macrophage inflammatory protein (MIP-3beta).	cadinol	2-9	C-C motif chemokine ligand 19	Homo sapiens	170-179
32426537-11	2020	Ethyl iso-allocholate demonstrated the highest binding affinity for caspase-1, cholest-22-ene-21-ol, 3,5-dehydro-6- methoxy-, pivalate for ADRB2 and TNF-alpha; and alpha-cadinol for COX-2.	cadinol	164-177	caspase 1	Rattus norvegicus	68-77
32426537-11	2020	Ethyl iso-allocholate demonstrated the highest binding affinity for caspase-1, cholest-22-ene-21-ol, 3,5-dehydro-6- methoxy-, pivalate for ADRB2 and TNF-alpha; and alpha-cadinol for COX-2.	cadinol	164-177	tumor necrosis factor	Rattus norvegicus	149-158
31895745-5	2020	The neuroprotective effect of HOC against Abeta(1-42)-induced neuronal apoptosis was assessed by Hoechst 33258 staining, reactive oxygen species (ROS) production, caspase-3 activation and caspase-3 activity.	cadinol	30-33	caspase 3	Rattus norvegicus	163-172
31895745-5	2020	The neuroprotective effect of HOC against Abeta(1-42)-induced neuronal apoptosis was assessed by Hoechst 33258 staining, reactive oxygen species (ROS) production, caspase-3 activation and caspase-3 activity.	cadinol	30-33	caspase 3	Rattus norvegicus	188-197
31895745-7	2020	The underlying molecular mechanisms of HOC in preventing Abeta(1-42)-induced neuronal apoptosis may be via inhibiting Abeta(1-42)-induced ROS production, attenuating Abeta(1-42)-induced caspase-3 activation and inhibiting caspase-3 activity.	cadinol	39-42	caspase 3	Rattus norvegicus	186-195
31895745-7	2020	The underlying molecular mechanisms of HOC in preventing Abeta(1-42)-induced neuronal apoptosis may be via inhibiting Abeta(1-42)-induced ROS production, attenuating Abeta(1-42)-induced caspase-3 activation and inhibiting caspase-3 activity.	cadinol	39-42	caspase 3	Rattus norvegicus	222-231