PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
16432839-5	2006	The bacterial homologue formamidopyrimidine-DNA glycosylase (FPG) is 80-fold faster than hOGG1 in repairing mutagenic oxidative lesions.	formamidopyrimidine	24-43	8-oxoguanine DNA glycosylase	Homo sapiens	89-94
19496823-2	2009	Correcting oxidative damage in purines and pyrimidines is the primary function of the enzymes formamidopyrimidine (faPy)-DNA glycosylase (Fpg) and endonuclease VIII (Nei) of the base excision repair pathway, respectively.	formamidopyrimidine	94-113	formamidopyrimidine-DNA glycosylase	Mycobacterium tuberculosis H37Rv	138-141
18582124-8	2008	The formamidopyrimidine derivative forms from ring opening of the guanine imidazole ring following C-8 oxidation in the N(7), N(9) disubstituted guanine.	formamidopyrimidine	4-23	homeobox C8	Homo sapiens	99-102
18393852-5	2008	To conceive new therapeutic strategies for this syndrome, we are investigating whether the oxidatively damaged DNA repair defect in Cockayne syndrome might be complemented by heterologous repair proteins, such as the Escherichia coli formamidopyrimidine-DNA glycosylase and endonuclease III.	formamidopyrimidine	234-253	endonuclease III	Escherichia coli	274-290
16928690-1	2006	Escherichia coli formamidopyrimidine-DNA glycosylase (Fpg) and human 8-oxoguanine-DNA glycosylase (hOgg1) initiate the base excision repair pathway for 7,8-dihydro-8-oxoguanine (8-oxoG) residues present in DNA.	formamidopyrimidine	17-36	8-oxoguanine DNA glycosylase	Homo sapiens	69-97
16928690-1	2006	Escherichia coli formamidopyrimidine-DNA glycosylase (Fpg) and human 8-oxoguanine-DNA glycosylase (hOgg1) initiate the base excision repair pathway for 7,8-dihydro-8-oxoguanine (8-oxoG) residues present in DNA.	formamidopyrimidine	17-36	8-oxoguanine DNA glycosylase	Homo sapiens	99-104
28098999-4	2017	We recently showed that formamidopyrimidine-DNA glycosylase (Fpg), a bacterial functional analog of OGG1, can selectively facilitate eversion of oxoG by stabilizing several intermediate states, and it is intriguing whether OGG1 also employs a similar mechanism in lesion recognition.	formamidopyrimidine	24-43	8-oxoguanine DNA glycosylase	Homo sapiens	100-104
28098999-4	2017	We recently showed that formamidopyrimidine-DNA glycosylase (Fpg), a bacterial functional analog of OGG1, can selectively facilitate eversion of oxoG by stabilizing several intermediate states, and it is intriguing whether OGG1 also employs a similar mechanism in lesion recognition.	formamidopyrimidine	24-43	8-oxoguanine DNA glycosylase	Homo sapiens	223-227
22749143-2	2012	The bifunctional formamidopyrimidine DNA glycosylase (Fpg) and endonuclease VIII (Nei) are members of the Fpg/Nei family, one of the two families of glycosylases that recognize oxidized DNA bases, the other being the HhH/GPD (or Nth) superfamily.	formamidopyrimidine	17-36	nei like DNA glycosylase 1	Homo sapiens	63-80
21696973-1	2011	In plants, 8-oxoguanine DNA glycosylase/lyase (OGG1) and formamidopyrimidine-DNA glycosylase (FPG) play similar roles within the base excision repair (BER) pathway involved in the removal of oxidized bases, e.g. 7,8-dihydro-8-oxoguanine (8-oxo-dG) and formamidopyrimidine (FAPy) lesions.	formamidopyrimidine	57-76	formamidopyrimidine-DNA glycosylase	Medicago truncatula	94-97
16798066-6	2006	o-PD and Cl-PD caused piperidine-labile and formamidopyrimidine-DNA glycosylase-sensitive lesions at cytosine and guanine residues respectively in the 5"-ACG-3" sequence, complementary to codon 273, a well-known hotspot of the human p53 tumor suppressor gene.	formamidopyrimidine	44-63	tumor protein p53	Homo sapiens	233-236
12948823-3	2003	Procarbazine plus Cu(II) induced piperidine-labile and formamidopyrimidine-DNA glycosylase-sensitive lesions at the 5"-ACG-3" sequence, complementary to a hotspot of the p53 gene, and the 5"-TG-3" sequence.	formamidopyrimidine	55-74	tumor protein p53	Homo sapiens	170-173
12402298-6	2002	With formamidopyrimidine-DNA glycosylase treatment, N-OH-AF induced cleavage at guanine residues, especially of the ACG sequence complementary to codon 273, a well-known hot spot of the p53 gene.	formamidopyrimidine	5-24	tumor protein p53	Homo sapiens	186-189
12137539-1	2002	The yields of gamma-radiation-induced single- and double-strand breaks (ssb"s and dsb"s) as well as base lesions, which are converted into detectable ssb by the base excision repair enzymes endonuclease III (Nth) and formamidopyrimidine-DNA glycosylase (Fpg), at 278 K have been measured as a function of the level of hydration of closed-circular plasmid DNA (pUC18) films.	formamidopyrimidine	217-236	small RNA binding exonuclease protection factor La	Homo sapiens	72-75
12067581-4	2002	The bacterial formamidopyrimidine-DNA glycosylase (Fpg protein) involved in base excision repair was inhibited by Cd(II), Cu(II) and Hg(II) with increasing efficiencies, whereas Co(II), As(III), Pb(II) and Ni(II) had no effect.	formamidopyrimidine	14-33	mitochondrially encoded cytochrome c oxidase II	Homo sapiens	178-184
12137539-1	2002	The yields of gamma-radiation-induced single- and double-strand breaks (ssb"s and dsb"s) as well as base lesions, which are converted into detectable ssb by the base excision repair enzymes endonuclease III (Nth) and formamidopyrimidine-DNA glycosylase (Fpg), at 278 K have been measured as a function of the level of hydration of closed-circular plasmid DNA (pUC18) films.	formamidopyrimidine	217-236	small RNA binding exonuclease protection factor La	Homo sapiens	150-153
9192816-1	1997	The frequency of oxidative base damage along the human p53 and PGK1 genes was determined at nucleotide resolution by cleaving DNA at oxidized bases with endonuclease III and formamidopyrimidine DNA glycosylase and then using the ligation-mediated PCR technique to map induced break frequency.	formamidopyrimidine	174-193	tumor protein p53	Homo sapiens	55-58
10882850-0	2000	Cell-cycle regulation, intracellular sorting and induced overexpression of the human NTH1 DNA glycosylase involved in removal of formamidopyrimidine residues from DNA.	formamidopyrimidine	129-148	nth like DNA glycosylase 1	Homo sapiens	85-89
9801319-7	1998	rOGG1 also acts on formamidopyrimidine (FaPy) residues, and the K m values on 8-oxoG and FaPy residues are 18.8 and 9.7 nM, respectively.	formamidopyrimidine	19-38	8-oxoguanine DNA glycosylase	Rattus norvegicus	0-5
11098850-1	2000	PURPOSE: To determine the increases in SSB and DSB yields after post gamma-irradiation incubation of plasmid DNA with the Escherichia coli base excision repair endonucleases formamidopyrimidine-DNA N-glycosylase (FPG) and endonuclease III (endo III).	formamidopyrimidine	174-193	single-stranded DNA-binding protein	Escherichia coli	39-42
11098850-1	2000	PURPOSE: To determine the increases in SSB and DSB yields after post gamma-irradiation incubation of plasmid DNA with the Escherichia coli base excision repair endonucleases formamidopyrimidine-DNA N-glycosylase (FPG) and endonuclease III (endo III).	formamidopyrimidine	174-193	endonuclease III	Escherichia coli	222-238
11098850-1	2000	PURPOSE: To determine the increases in SSB and DSB yields after post gamma-irradiation incubation of plasmid DNA with the Escherichia coli base excision repair endonucleases formamidopyrimidine-DNA N-glycosylase (FPG) and endonuclease III (endo III).	formamidopyrimidine	174-193	endonuclease III	Escherichia coli	240-248
9192816-1	1997	The frequency of oxidative base damage along the human p53 and PGK1 genes was determined at nucleotide resolution by cleaving DNA at oxidized bases with endonuclease III and formamidopyrimidine DNA glycosylase and then using the ligation-mediated PCR technique to map induced break frequency.	formamidopyrimidine	174-193	phosphoglycerate kinase 1	Homo sapiens	63-67
8824320-5	1996	The damage to gamma-actin and DNA polymerase-beta genes was detected within 20 min of reperfusion based on the presence of formamidopyrimidine DNA N-glycosylase-sensitive sites.	formamidopyrimidine	123-142	actin, gamma, cytoplasmic 1	Mus musculus	14-25
8824320-5	1996	The damage to gamma-actin and DNA polymerase-beta genes was detected within 20 min of reperfusion based on the presence of formamidopyrimidine DNA N-glycosylase-sensitive sites.	formamidopyrimidine	123-142	polymerase (DNA directed), beta	Mus musculus	30-49
8555407-2	1995	The 1H and 13C NMR features of the two modified nucleosides obtained in DMSO-d6 are indicative of a similar formamidopyrimidine structure for the base residue (the ring-opened form of a C-8 hydroxylated purine).	formamidopyrimidine	108-127	homeobox C8	Homo sapiens	186-189
8034633-1	1994	5-Hydroxy-2"-deoxycytidine and 5-hydroxy-2"-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2"-deoxyuridine is a substrate for uracil DNA N-glycosylase.	formamidopyrimidine	114-133	endonuclease III	Escherichia coli	93-109
34517666-3	2021	In this assay, the 8-oxoG damages in DNA can generate free 3" OH with the assistance of formamidopyrimidine DNA glycosylase (Fpg) and polynucleotide kinase (PNK), which subsequently triggers the incorporation of abundant Cy5-labeled dUTPs via terminal deoxynucleotidyl transferase (TDT)-mediated site-specific hyperbranched nucleic acid amplification.	formamidopyrimidine	88-107	polynucleotide kinase 3'-phosphatase	Homo sapiens	157-160
34517666-3	2021	In this assay, the 8-oxoG damages in DNA can generate free 3" OH with the assistance of formamidopyrimidine DNA glycosylase (Fpg) and polynucleotide kinase (PNK), which subsequently triggers the incorporation of abundant Cy5-labeled dUTPs via terminal deoxynucleotidyl transferase (TDT)-mediated site-specific hyperbranched nucleic acid amplification.	formamidopyrimidine	88-107	DNA nucleotidylexotransferase	Homo sapiens	243-280
34517666-3	2021	In this assay, the 8-oxoG damages in DNA can generate free 3" OH with the assistance of formamidopyrimidine DNA glycosylase (Fpg) and polynucleotide kinase (PNK), which subsequently triggers the incorporation of abundant Cy5-labeled dUTPs via terminal deoxynucleotidyl transferase (TDT)-mediated site-specific hyperbranched nucleic acid amplification.	formamidopyrimidine	88-107	DNA nucleotidylexotransferase	Homo sapiens	282-285
34791445-7	2022	Notably, mutating FORMAMIDOPYRIMIDINE DNA GLYCOSYLASE (FPG) in zdp ape2 sog1 partially recovered its radicle growth, demonstrating that DNA 3"-blocks generated by FPG caused the meristematic defects.	formamidopyrimidine	18-37	NAC (No Apical Meristem) domain transcriptional regulator superfamily protein	Arabidopsis thaliana	72-76
31284385-7	2019	Formamidopyrimidine DNA glycosylase (Fpg)-sensitive sites accumulated in mtDNA from OGG1-/- but not from NTH1-/- mice.	formamidopyrimidine	0-19	8-oxoguanine DNA-glycosylase 1	Mus musculus	84-88