PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 9681345-1 1998 OBJECTIVE: To investigate the immediate and long-term effects of photodynamic therapy with delta-aminolevulinic acid (ALA-PDT) on superficial basal cell carcinomas (BCC) and superficial squamous cell carcinomas (SCC). 1-phenyl-3,3-dimethyltriazene 118-125 serpin family B member 3 Homo sapiens 212-215 31945545-0 2020 MOP-dependent enhancement of methadone on the effectiveness of ALA-PDT for A172 cells by upregulating phosphorylated JNK and BCL2. 1-phenyl-3,3-dimethyltriazene 63-70 opioid receptor mu 1 Homo sapiens 0-3 31945545-0 2020 MOP-dependent enhancement of methadone on the effectiveness of ALA-PDT for A172 cells by upregulating phosphorylated JNK and BCL2. 1-phenyl-3,3-dimethyltriazene 63-70 mitogen-activated protein kinase 8 Homo sapiens 117-120 31945545-0 2020 MOP-dependent enhancement of methadone on the effectiveness of ALA-PDT for A172 cells by upregulating phosphorylated JNK and BCL2. 1-phenyl-3,3-dimethyltriazene 63-70 BCL2 apoptosis regulator Homo sapiens 125-129 31945545-7 2020 Phosphorylated JNK and BCL2 induced by ALA-PDT were promoted in the presence of methadone (p < 0.05). 1-phenyl-3,3-dimethyltriazene 39-46 mitogen-activated protein kinase 8 Homo sapiens 15-18 31945545-7 2020 Phosphorylated JNK and BCL2 induced by ALA-PDT were promoted in the presence of methadone (p < 0.05). 1-phenyl-3,3-dimethyltriazene 39-46 BCL2 apoptosis regulator Homo sapiens 23-27 31945545-9 2020 CONCLUSIONS: The results suggest that apoptosis induced by ALA-PDT is enhanced by methadone, mostly MOP-mediated, through the upregulation of accumulation of phosphorylated JNK and BCL2, leading to a promotion of cytotoxicity of ALA-PDT for A172 cells. 1-phenyl-3,3-dimethyltriazene 59-66 opioid receptor mu 1 Homo sapiens 100-103 31945545-9 2020 CONCLUSIONS: The results suggest that apoptosis induced by ALA-PDT is enhanced by methadone, mostly MOP-mediated, through the upregulation of accumulation of phosphorylated JNK and BCL2, leading to a promotion of cytotoxicity of ALA-PDT for A172 cells. 1-phenyl-3,3-dimethyltriazene 59-66 mitogen-activated protein kinase 8 Homo sapiens 173-176 31945545-9 2020 CONCLUSIONS: The results suggest that apoptosis induced by ALA-PDT is enhanced by methadone, mostly MOP-mediated, through the upregulation of accumulation of phosphorylated JNK and BCL2, leading to a promotion of cytotoxicity of ALA-PDT for A172 cells. 1-phenyl-3,3-dimethyltriazene 59-66 BCL2 apoptosis regulator Homo sapiens 181-185 31945545-9 2020 CONCLUSIONS: The results suggest that apoptosis induced by ALA-PDT is enhanced by methadone, mostly MOP-mediated, through the upregulation of accumulation of phosphorylated JNK and BCL2, leading to a promotion of cytotoxicity of ALA-PDT for A172 cells. 1-phenyl-3,3-dimethyltriazene 229-236 opioid receptor mu 1 Homo sapiens 100-103 31945545-9 2020 CONCLUSIONS: The results suggest that apoptosis induced by ALA-PDT is enhanced by methadone, mostly MOP-mediated, through the upregulation of accumulation of phosphorylated JNK and BCL2, leading to a promotion of cytotoxicity of ALA-PDT for A172 cells. 1-phenyl-3,3-dimethyltriazene 229-236 mitogen-activated protein kinase 8 Homo sapiens 173-176 31849516-0 2019 NLRP3 Inflammasome Mediated Interleukin-1beta Production in Cancer-Associated Fibroblast Contributes to ALA-PDT for Cutaneous Squamous Cell Carcinoma. 1-phenyl-3,3-dimethyltriazene 104-111 NLR family, pyrin domain containing 3 Mus musculus 0-5 31849516-0 2019 NLRP3 Inflammasome Mediated Interleukin-1beta Production in Cancer-Associated Fibroblast Contributes to ALA-PDT for Cutaneous Squamous Cell Carcinoma. 1-phenyl-3,3-dimethyltriazene 104-111 interleukin 1 beta Mus musculus 28-45 31849516-7 2019 In vivo, the inhibition of ALA-PDT on tumor growth of cutaneous squamous cell carcinoma (cSCC) mice in the group with intralesional injection of anti-IL1beta mAb or caspase1-inhibitor was significantly weaker than the control groups. 1-phenyl-3,3-dimethyltriazene 27-34 caspase 1 Mus musculus 165-173