PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
33778403-7	2021	For example, harvesting ICBG caused a significant increase in sclerostin expression.	icbg	24-28	sclerostin	Oryctolagus cuniculus	62-72
30148776-11	2018	CONCLUSION: In the treatment of alveolar cleft deformities, operative material costs were greater in the DBX/rhBMP-2 group but-secondary to decreased hospital, anesthesia, pharmacy, and operating room costs-DBX/rhBMP-2 was more cost-effective than ICBG.	icbg	248-252	DEAD-box helicase 3 X-linked	Homo sapiens	105-108
24373796-9	2014	The in vivo model also demonstrated that the concentration of interstitial free cortisol is increased locally at a site of inflammation where iCBG is cleaved to form eCBG by the activity of elastase released by neutrophils.	icbg	142-146	elastase, neutrophil expressed	Homo sapiens	190-198
22941273-1	2012	BACKGROUND: Recombinant human bone morphogenetic protein-2 (rhBMP-2) as a substitute for iliac crest bone graft (ICBG) has been increasingly widely used in lumbar fusion.	icbg	113-117	bone morphogenetic protein 2	Homo sapiens	30-58
20551786-4	2010	A recent emphasis on the morbidity of ICBG has helped to fuel the costly growth in clinical use of alternatives, such as bone morphogenetic protein-2.	icbg	38-42	bone morphogenetic protein 2	Homo sapiens	121-149
19092613-18	2008	CONCLUSION: RhBMP-2/ACS is a viable ICBG replacement in older patients in terms of safety, clinical efficacy, and cost-effectiveness.	icbg	36-40	1-aminocyclopropane-1-carboxylate synthase homolog (inactive)	Homo sapiens	20-23
18758349-12	2008	rBMP-2 was more efficacious to ICBG in promoting fusion (RR = 0.29, 95% CI = 0.18-0.47, P < 0.00001), whereas rhBMP-7 (osteogenic protein-1) appeared equivalent to ICBG in that respect (RR = 1.17, 95% CI = 0.54-2.54, P = 0.70).	icbg	167-171	bone morphogenetic protein 2	Rattus norvegicus	0-6
9642988-7	1998	Tubular expression of DR, ICAM-1 and VCAM-1 were positive in 25%, 40%, 45% of ICBG and 91.7%, 100%, 100% of CBG.	icbg	78-82	intercellular adhesion molecule 1	Homo sapiens	26-32
9642988-7	1998	Tubular expression of DR, ICAM-1 and VCAM-1 were positive in 25%, 40%, 45% of ICBG and 91.7%, 100%, 100% of CBG.	icbg	78-82	vascular cell adhesion molecule 1	Homo sapiens	37-43
20582554-1	2011	Bone morphogenetic protein (BMP) is commonly used as an ICBG substitute for transforaminal lumbar interbody spine fusion (TLIF).	icbg	56-60	bone morphogenetic protein 1	Homo sapiens	0-26
20582554-1	2011	Bone morphogenetic protein (BMP) is commonly used as an ICBG substitute for transforaminal lumbar interbody spine fusion (TLIF).	icbg	56-60	bone morphogenetic protein 1	Homo sapiens	28-31