PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
17113196-4	2007	At a resting potential (-70 mV), the IC(50) values of CPCn, CPPy, TGDMAP and ATGDMAP for NR1/NR2A receptors were 0.5+/-0.1, 1.0+/-0.2, 8.0+/-0.8 and 4.9+/-0.5 microM, respectively.	cppy	60-64	glutamate ionotropic receptor NMDA type subunit 1 L homeolog	Xenopus laevis	89-92
18247433-7	2008	Upon exposure to thrombin, the CPPy nanotube FET sensors showed a decrease in current flow, which was probably attributed to the dipole-dipole or dipole-charge interaction between thrombin proteins and the aptamer-conjugated polymer chains.	cppy	31-35	coagulation factor II, thrombin	Homo sapiens	17-25
18247433-7	2008	Upon exposure to thrombin, the CPPy nanotube FET sensors showed a decrease in current flow, which was probably attributed to the dipole-dipole or dipole-charge interaction between thrombin proteins and the aptamer-conjugated polymer chains.	cppy	31-35	coagulation factor II, thrombin	Homo sapiens	180-188
17409494-0	2007	A novel cyclophane compound, CPPy, facilitates NGF-induced TrkA signal transduction and induces cell differentiation in neuroblastoma.	cppy	29-33	neurotrophic receptor tyrosine kinase 1	Homo sapiens	59-63
17409494-3	2007	A novel cyclophane, cyclophane pyridine (CPPy), was designed to conserve the tyrosine phosphorylation of TrkA, thereby enhancing NGF/TrkA signal transduction.	cppy	41-45	neurotrophic receptor tyrosine kinase 1	Homo sapiens	105-109
17409494-3	2007	A novel cyclophane, cyclophane pyridine (CPPy), was designed to conserve the tyrosine phosphorylation of TrkA, thereby enhancing NGF/TrkA signal transduction.	cppy	41-45	neurotrophic receptor tyrosine kinase 1	Homo sapiens	133-137
17409494-5	2007	As determined by Western blotting, TrkA (Y490) phosphorylation was enhanced by the combination of CPPy (10(-8) M) and NGF (100 ng/ml) compared with NGF alone.	cppy	98-102	neurotrophic receptor tyrosine kinase 1	Homo sapiens	35-39
17409494-7	2007	Moreover, CPPy induced the morphological differentiation of NB cells, leading to expression of the neuronal marker gene GAP-43.	cppy	10-14	growth associated protein 43	Homo sapiens	120-126
17409494-8	2007	These data suggest that CPPy can induce the differentiation of NB cell lines by facilitating NGF-induced TrkA/Ras/MAPK signal transduction, and may therefore be an effective therapeutic agent for NB.	cppy	24-28	neurotrophic receptor tyrosine kinase 1	Homo sapiens	105-109
32604807-5	2020	Carboxyl polypyrrole (CPPy) in the nanocomposite was protonated to increase the charge transfer rate during gas detection.	cppy	22-26	gastrin	Homo sapiens	108-111
17113196-4	2007	At a resting potential (-70 mV), the IC(50) values of CPCn, CPPy, TGDMAP and ATGDMAP for NR1/NR2A receptors were 0.5+/-0.1, 1.0+/-0.2, 8.0+/-0.8 and 4.9+/-0.5 microM, respectively.	cppy	60-64	glutamate receptor ionotropic, NMDA 2A-like	Xenopus laevis	93-97