PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
33868356-6	2021	The BdCYP711A29 protein is homologous to the Arabidopsis thaliana MAX1 and Oryza sativa MAX1-like CYPs representing key components of the strigolactone biosynthesis.	GR24 strigolactone	138-151	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	66-70
33756344-1	2021	ARABIDOPSIS: SMAX1/SMXL (SUPPRESSOR OF MAX2 1/SMAX1-LIKE) proteins function as transcriptional repressors in karrikin and strigolactone (SL) signaling pathways and regulate plant architecture.	GR24 strigolactone	122-135	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	13-18
33756344-1	2021	ARABIDOPSIS: SMAX1/SMXL (SUPPRESSOR OF MAX2 1/SMAX1-LIKE) proteins function as transcriptional repressors in karrikin and strigolactone (SL) signaling pathways and regulate plant architecture.	GR24 strigolactone	122-135	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	25-56
33909299-0	2021	HEXOKINASE1 signalling promotes shoot branching and interacts with cytokinin and strigolactone pathways.	GR24 strigolactone	81-94	hexokinase 1	Arabidopsis thaliana	0-11
33909299-8	2021	HXK1-deficient plants displayed decreased cytokinin levels and increased expression of MAX2, which is required for strigolactone signalling.	GR24 strigolactone	115-128	RNI-like superfamily protein	Arabidopsis thaliana	87-91
33986761-4	2021	Ectopic expression of AtCXE20 in Arabidopsis and maize resulted in phenotypes characteristic of strigolactone (SL)-deficient mutants, including increased branching and tillering, decreased plant height, delayed senescence, hyposensitivity to ethylene, and reduced flavonols.	GR24 strigolactone	96-109	carboxyesterase 20	Arabidopsis thaliana	22-29
33868356-6	2021	The BdCYP711A29 protein is homologous to the Arabidopsis thaliana MAX1 and Oryza sativa MAX1-like CYPs representing key components of the strigolactone biosynthesis.	GR24 strigolactone	138-151	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	88-92
32888808-0	2020	Does Karrikin Signaling Shape the Rhizomicrobiome via the Strigolactone Biosynthetic Pathway?	GR24 strigolactone	58-71	KAR	Homo sapiens	5-13
34028688-3	2021	Here we describe an innovative quantitative bioassay based on Arabidopsis transgenic lines expressing AtD14 fused to the firefly luciferase, developed to identify new strigolactone analogs capable to activate the strigolactone signaling.	GR24 strigolactone	167-180	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	102-107
34028688-3	2021	Here we describe an innovative quantitative bioassay based on Arabidopsis transgenic lines expressing AtD14 fused to the firefly luciferase, developed to identify new strigolactone analogs capable to activate the strigolactone signaling.	GR24 strigolactone	213-226	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	102-107
34028691-3	2021	However, in the case of strigolactone receptors (e.g., D14, AtD14, DAD2, RMS3) from plants, the Tm tends to be reduced in the presence of strigolactones.	GR24 strigolactone	24-37	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	55-58
34028691-3	2021	However, in the case of strigolactone receptors (e.g., D14, AtD14, DAD2, RMS3) from plants, the Tm tends to be reduced in the presence of strigolactones.	GR24 strigolactone	24-37	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	60-65
32888808-2	2020	provides evidence of the interaction between the karrikin (KAR) signaling and strigolactone (SL) biosynthetic pathways.	GR24 strigolactone	78-91	KAR	Homo sapiens	49-57
32888808-2	2020	provides evidence of the interaction between the karrikin (KAR) signaling and strigolactone (SL) biosynthetic pathways.	GR24 strigolactone	78-91	KAR	Homo sapiens	59-62
32393176-12	2020	Furthermore, the S9_154,978,426 locus on chromosome 9 was found at 2.61 Mb close to the ZmCCD1 gene known to be associated with the reduction of strigolactone production in the maize roots.	GR24 strigolactone	145-158	white cap1	Zea mays	88-94
32528176-4	2020	Here we use a synthetic strigolactone to identify 401 strigolactone-responsive genes in Arabidopsis, and show that these plant hormones regulate shoot branching, leaf shape and anthocyanin accumulation mainly through transcriptional activation of the BRANCHED 1, TCP DOMAIN PROTEIN 1 and PRODUCTION OF ANTHOCYANIN PIGMENT 1 genes.	GR24 strigolactone	24-37	TCP family transcription factor	Arabidopsis thaliana	251-261
32528176-4	2020	Here we use a synthetic strigolactone to identify 401 strigolactone-responsive genes in Arabidopsis, and show that these plant hormones regulate shoot branching, leaf shape and anthocyanin accumulation mainly through transcriptional activation of the BRANCHED 1, TCP DOMAIN PROTEIN 1 and PRODUCTION OF ANTHOCYANIN PIGMENT 1 genes.	GR24 strigolactone	54-67	TCP family transcription factor	Arabidopsis thaliana	251-261
32528176-4	2020	Here we use a synthetic strigolactone to identify 401 strigolactone-responsive genes in Arabidopsis, and show that these plant hormones regulate shoot branching, leaf shape and anthocyanin accumulation mainly through transcriptional activation of the BRANCHED 1, TCP DOMAIN PROTEIN 1 and PRODUCTION OF ANTHOCYANIN PIGMENT 1 genes.	GR24 strigolactone	54-67	production of anthocyanin pigment 1	Arabidopsis thaliana	288-323
32528176-5	2020	We find that SMXL6 targets 729 genes in the Arabidopsis genome and represses the transcription of SMXL6, SMXL7 and SMXL8 by binding directly to their promoters, showing that SMXL6 serves as an autoregulated transcription factor to maintain the homeostasis of strigolactone signalling.	GR24 strigolactone	259-272	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	13-18
32528176-5	2020	We find that SMXL6 targets 729 genes in the Arabidopsis genome and represses the transcription of SMXL6, SMXL7 and SMXL8 by binding directly to their promoters, showing that SMXL6 serves as an autoregulated transcription factor to maintain the homeostasis of strigolactone signalling.	GR24 strigolactone	259-272	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	98-103
32528176-5	2020	We find that SMXL6 targets 729 genes in the Arabidopsis genome and represses the transcription of SMXL6, SMXL7 and SMXL8 by binding directly to their promoters, showing that SMXL6 serves as an autoregulated transcription factor to maintain the homeostasis of strigolactone signalling.	GR24 strigolactone	259-272	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	105-110
32528176-5	2020	We find that SMXL6 targets 729 genes in the Arabidopsis genome and represses the transcription of SMXL6, SMXL7 and SMXL8 by binding directly to their promoters, showing that SMXL6 serves as an autoregulated transcription factor to maintain the homeostasis of strigolactone signalling.	GR24 strigolactone	259-272	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	115-120
32528176-5	2020	We find that SMXL6 targets 729 genes in the Arabidopsis genome and represses the transcription of SMXL6, SMXL7 and SMXL8 by binding directly to their promoters, showing that SMXL6 serves as an autoregulated transcription factor to maintain the homeostasis of strigolactone signalling.	GR24 strigolactone	259-272	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	98-103
32358074-0	2020	Strigolactone and Karrikin Signaling Pathways Elicit Ubiquitination and Proteolysis of SMXL2 to Regulate Hypocotyl Elongation in Arabidopsis thaliana.	GR24 strigolactone	0-13	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	87-92
32022953-1	2020	Functional analyses of various strigolactone-deficient mutants have demonstrated that strigolactones enhance drought resistance; however, the mechanistic involvement of the strigolactone receptor DWARF14 (D14) in this trait remains elusive.	GR24 strigolactone	31-44	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	205-208
32022953-1	2020	Functional analyses of various strigolactone-deficient mutants have demonstrated that strigolactones enhance drought resistance; however, the mechanistic involvement of the strigolactone receptor DWARF14 (D14) in this trait remains elusive.	GR24 strigolactone	86-100	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	205-208
32022953-1	2020	Functional analyses of various strigolactone-deficient mutants have demonstrated that strigolactones enhance drought resistance; however, the mechanistic involvement of the strigolactone receptor DWARF14 (D14) in this trait remains elusive.	GR24 strigolactone	86-99	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	205-208
32327664-0	2020	Arabidopsis FHY3 and FAR1 integrate light and strigolactone signaling to regulate branching.	GR24 strigolactone	46-59	far-red elongated hypocotyls 3	Arabidopsis thaliana	12-16
32355217-0	2020	The negative regulator SMAX1 controls mycorrhizal symbiosis and strigolactone biosynthesis in rice.	GR24 strigolactone	64-77	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	23-28
32355217-7	2020	Similarly, rice SMAX1 negatively controls strigolactone biosynthesis, demonstrating an unexpected crosstalk between the strigolactone and karrikin signalling pathways.	GR24 strigolactone	42-55	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	16-21
32355217-7	2020	Similarly, rice SMAX1 negatively controls strigolactone biosynthesis, demonstrating an unexpected crosstalk between the strigolactone and karrikin signalling pathways.	GR24 strigolactone	120-133	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	16-21
32355217-8	2020	We conclude that removal of SMAX1, resulting from D14L signalling activation, de-represses essential symbiotic programmes and increases strigolactone hormone production.	GR24 strigolactone	136-149	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	28-33
32327664-0	2020	Arabidopsis FHY3 and FAR1 integrate light and strigolactone signaling to regulate branching.	GR24 strigolactone	46-59	FRS (FAR1 Related Sequences) transcription factor family	Arabidopsis thaliana	21-25
32327664-3	2020	Here, we report that in Arabidopsis, FHY3 and FAR1, two homologous transcription factors essential for phytochrome A-mediated light signaling, and SMXL6/SMXL7/SMXL8, three key repressors of the strigolactone (SL) signaling pathway, directly interact with SPL9 and SPL15 and suppress their transcriptional activation of BRC1, a key repressor of branching, thus promoting branching.	GR24 strigolactone	194-207	far-red elongated hypocotyls 3	Arabidopsis thaliana	37-41
32327664-3	2020	Here, we report that in Arabidopsis, FHY3 and FAR1, two homologous transcription factors essential for phytochrome A-mediated light signaling, and SMXL6/SMXL7/SMXL8, three key repressors of the strigolactone (SL) signaling pathway, directly interact with SPL9 and SPL15 and suppress their transcriptional activation of BRC1, a key repressor of branching, thus promoting branching.	GR24 strigolactone	194-207	FRS (FAR1 Related Sequences) transcription factor family	Arabidopsis thaliana	46-50
32327664-3	2020	Here, we report that in Arabidopsis, FHY3 and FAR1, two homologous transcription factors essential for phytochrome A-mediated light signaling, and SMXL6/SMXL7/SMXL8, three key repressors of the strigolactone (SL) signaling pathway, directly interact with SPL9 and SPL15 and suppress their transcriptional activation of BRC1, a key repressor of branching, thus promoting branching.	GR24 strigolactone	194-207	phytochrome A	Arabidopsis thaliana	103-116
32327664-3	2020	Here, we report that in Arabidopsis, FHY3 and FAR1, two homologous transcription factors essential for phytochrome A-mediated light signaling, and SMXL6/SMXL7/SMXL8, three key repressors of the strigolactone (SL) signaling pathway, directly interact with SPL9 and SPL15 and suppress their transcriptional activation of BRC1, a key repressor of branching, thus promoting branching.	GR24 strigolactone	194-207	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	147-152
32327664-3	2020	Here, we report that in Arabidopsis, FHY3 and FAR1, two homologous transcription factors essential for phytochrome A-mediated light signaling, and SMXL6/SMXL7/SMXL8, three key repressors of the strigolactone (SL) signaling pathway, directly interact with SPL9 and SPL15 and suppress their transcriptional activation of BRC1, a key repressor of branching, thus promoting branching.	GR24 strigolactone	194-207	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	153-158
32327664-3	2020	Here, we report that in Arabidopsis, FHY3 and FAR1, two homologous transcription factors essential for phytochrome A-mediated light signaling, and SMXL6/SMXL7/SMXL8, three key repressors of the strigolactone (SL) signaling pathway, directly interact with SPL9 and SPL15 and suppress their transcriptional activation of BRC1, a key repressor of branching, thus promoting branching.	GR24 strigolactone	194-207	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	159-164
32327664-3	2020	Here, we report that in Arabidopsis, FHY3 and FAR1, two homologous transcription factors essential for phytochrome A-mediated light signaling, and SMXL6/SMXL7/SMXL8, three key repressors of the strigolactone (SL) signaling pathway, directly interact with SPL9 and SPL15 and suppress their transcriptional activation of BRC1, a key repressor of branching, thus promoting branching.	GR24 strigolactone	194-207	squamosa promoter binding protein-like 9	Arabidopsis thaliana	255-259
32327664-3	2020	Here, we report that in Arabidopsis, FHY3 and FAR1, two homologous transcription factors essential for phytochrome A-mediated light signaling, and SMXL6/SMXL7/SMXL8, three key repressors of the strigolactone (SL) signaling pathway, directly interact with SPL9 and SPL15 and suppress their transcriptional activation of BRC1, a key repressor of branching, thus promoting branching.	GR24 strigolactone	194-207	squamosa promoter binding protein-like 15	Arabidopsis thaliana	264-269
32327664-3	2020	Here, we report that in Arabidopsis, FHY3 and FAR1, two homologous transcription factors essential for phytochrome A-mediated light signaling, and SMXL6/SMXL7/SMXL8, three key repressors of the strigolactone (SL) signaling pathway, directly interact with SPL9 and SPL15 and suppress their transcriptional activation of BRC1, a key repressor of branching, thus promoting branching.	GR24 strigolactone	194-207	TCP family transcription factor	Arabidopsis thaliana	319-323
32017526-7	2020	Collectively, the present work shows the anti-neuroinflammatory and glia/neuroprotective properties of GR24 making SLs promising scaffolds for the development of novel anti-AD candidates.	GR24 strigolactone	115-118	taste receptor, type 2, member 124	Mus musculus	103-107
32295207-0	2020	Negative Roles of Strigolactone-Related SMXL6, 7 and 8 Proteins in Drought Resistance in Arabidopsis.	GR24 strigolactone	18-31	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	40-54
32295207-1	2020	Previous investigations have shown that the SUPPRESSORS OF MAX2 1-LIKE6, 7 and 8 (SMXL6, 7 and 8) proteins redundantly repress strigolactone (SL) signaling in plant growth and development.	GR24 strigolactone	127-140	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	82-96
31921270-0	2019	The Calcium-Dependent Protein Kinase CPK33 Mediates Strigolactone-Induced Stomatal Closure in Arabidopsis thaliana.	GR24 strigolactone	52-65	calcium-dependent protein kinase 1	Arabidopsis thaliana	4-36
31921270-0	2019	The Calcium-Dependent Protein Kinase CPK33 Mediates Strigolactone-Induced Stomatal Closure in Arabidopsis thaliana.	GR24 strigolactone	52-65	calcium-dependent protein kinase 33	Arabidopsis thaliana	37-42
33404550-0	2020	BES1 Functions as the Co-regulator of D53-like SMXLs to Inhibit BRC1 Expression in Strigolactone-Regulated Shoot Branching in Arabidopsis.	GR24 strigolactone	83-96	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	0-4
33404550-0	2020	BES1 Functions as the Co-regulator of D53-like SMXLs to Inhibit BRC1 Expression in Strigolactone-Regulated Shoot Branching in Arabidopsis.	GR24 strigolactone	83-96	TCP family transcription factor	Arabidopsis thaliana	64-68
31431215-0	2019	Design, Synthesis and Biological Evaluation of Strigolactone and Strigolactam Derivatives for Potential Crop Enhancement Applications in Modern Agriculture.	GR24 strigolactone	47-60	LUC7 like 3 pre-mRNA splicing factor	Homo sapiens	104-108
31351052-0	2019	The strigolactone analog GR-24 inhibits angiogenesis in vivo and in vitro by a mechanism involving cytoskeletal reorganization and VEGFR2 signalling.	GR24 strigolactone	4-17	kinase insert domain receptor	Gallus gallus	131-137
31546850-7	2019	More specifically, 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 4 (ACC4) and PROTEIN KINASE 3 (PKS3) displayed contrasting expression patterns, indicating a regulatory mechanism in SL signaling pathway to control different phenotypes apart from branching phenotype.	GR24 strigolactone	179-181	1-aminocyclopropane-1-carboxylate synthase 4	Arabidopsis thaliana	19-63
31546850-7	2019	More specifically, 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 4 (ACC4) and PROTEIN KINASE 3 (PKS3) displayed contrasting expression patterns, indicating a regulatory mechanism in SL signaling pathway to control different phenotypes apart from branching phenotype.	GR24 strigolactone	179-181	1-aminocyclopropane-1-carboxylate synthase 4	Arabidopsis thaliana	65-69
31546850-7	2019	More specifically, 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 4 (ACC4) and PROTEIN KINASE 3 (PKS3) displayed contrasting expression patterns, indicating a regulatory mechanism in SL signaling pathway to control different phenotypes apart from branching phenotype.	GR24 strigolactone	179-181	CBL-interacting protein kinase 15	Arabidopsis thaliana	75-91
31546850-7	2019	More specifically, 1-AMINOCYCLOPROPANE-1-CARBOXYLATE SYNTHASE 4 (ACC4) and PROTEIN KINASE 3 (PKS3) displayed contrasting expression patterns, indicating a regulatory mechanism in SL signaling pathway to control different phenotypes apart from branching phenotype.	GR24 strigolactone	179-181	CBL-interacting protein kinase 15	Arabidopsis thaliana	93-97
31012494-0	2019	Strigolactone represses the synthesis of melatonin, thereby inducing floral transition in Arabidopsis thaliana in an FLC-dependent manner.	GR24 strigolactone	0-13	K-box region and MADS-box transcription factor family protein	Arabidopsis thaliana	117-120
31134630-7	2019	Finally, CYP707As and WRKY33 also modulated Arabidopsis root architecture in response to the synthetic strigolactone rac-GR24, and wrky33-1 exhibited a shoot hyperbranched phenotype.	GR24 strigolactone	103-116	WRKY DNA-binding protein 33	Arabidopsis thaliana	22-28
31245785-3	2019	Recently, we demonstrated that the irx syndrome in the trichome birefringence-like 29/eskimo1 (tbl29/esk1) mutant is dependent on MORE AXILLARY GROWTH 4 (MAX4), a key enzyme in the biosynthesis of the phytohormone strigolactone (SL).	GR24 strigolactone	214-227	trichome birefringence-like protein (DUF828)	Arabidopsis thaliana	55-93
30464344-2	2018	In the inhibition of shoot branching, the alpha/beta hydrolase D14-which metabolizes strigolactone-interacts with the F-box protein D3 to ubiquitinate and degrade the transcription repressor D53.	GR24 strigolactone	85-98	TPD52 like 1	Homo sapiens	191-194
30795866-2	2019	Recently, an F-box protein, called MAX2 (more axillary growth 2) was identified as a key component regulating many growth and developmental processes through the strigolactone and/or karrikin pathways.	GR24 strigolactone	162-175	RNI-like superfamily protein	Arabidopsis thaliana	35-39
30738662-0	2019	Chemical screening of novel strigolactone agonists that specifically interact with DWARF14 protein.	GR24 strigolactone	28-41	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	83-90
30902042-8	2019	Transcripts coding for GA20ox, D14, MAX2 and SMAX1-like proteins involved in gibberellin biosynthesis and strigolactone signalling, were reduced.	GR24 strigolactone	106-119	androgen receptor	Homo sapiens	45-50
30643123-0	2019	Strigolactone perception and deactivation by a hydrolase receptor DWARF14.	GR24 strigolactone	0-13	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	66-73
30643123-1	2019	The perception mechanism for the strigolactone (SL) class of plant hormones has been a subject of debate because their receptor, DWARF14 (D14), is an alpha/beta-hydrolase that can cleave SLs.	GR24 strigolactone	33-46	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	129-136
30643123-1	2019	The perception mechanism for the strigolactone (SL) class of plant hormones has been a subject of debate because their receptor, DWARF14 (D14), is an alpha/beta-hydrolase that can cleave SLs.	GR24 strigolactone	33-46	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	138-141
31245785-3	2019	Recently, we demonstrated that the irx syndrome in the trichome birefringence-like 29/eskimo1 (tbl29/esk1) mutant is dependent on MORE AXILLARY GROWTH 4 (MAX4), a key enzyme in the biosynthesis of the phytohormone strigolactone (SL).	GR24 strigolactone	214-227	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	130-152
31245785-3	2019	Recently, we demonstrated that the irx syndrome in the trichome birefringence-like 29/eskimo1 (tbl29/esk1) mutant is dependent on MORE AXILLARY GROWTH 4 (MAX4), a key enzyme in the biosynthesis of the phytohormone strigolactone (SL).	GR24 strigolactone	214-227	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	154-158
30861026-1	2019	In plants, the enzyme CCD8 (carotenoid cleavage dioxygenase 8) is involved in the synthesis of an important hormone, strigolactone, and therefore, plays an important role in controlling growth and development.	GR24 strigolactone	117-130	carotenoid cleavage dioxygenase	Zea mays	22-26
30464344-6	2018	The D3 C-terminal alpha-helix enables D14 to recruit D53 in a strigolactone-dependent manner, which in turn activates the hydrolase.	GR24 strigolactone	62-75	TPD52 like 1	Homo sapiens	53-56
29982999-8	2018	We developed a KAI2-active version of the fluorescent strigolactone analogue Yoshimulactone Green to show that KAI2 D184N exhibits normal rates of ligand hydrolysis.	GR24 strigolactone	54-67	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	15-19
29982999-8	2018	We developed a KAI2-active version of the fluorescent strigolactone analogue Yoshimulactone Green to show that KAI2 D184N exhibits normal rates of ligand hydrolysis.	GR24 strigolactone	54-67	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	111-115
30728949-0	2018	Strigolactone GR24 upregulates target genes of the cytoprotective transcription factor Nrf2 in skeletal muscle.	GR24 strigolactone	0-13	NFE2 like bZIP transcription factor 2	Rattus norvegicus	87-91
29982999-10	2018	Remarkably, KAI2 D184N degradation was hypersensitive to karrikins, but showed a normal response to strigolactone analogues, implying that these butenolides may interact differently with KAI2.	GR24 strigolactone	100-113	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	12-16
29550483-0	2018	Strigolactone GR24 and pinosylvin attenuate adipogenesis and inflammation of white adipocytes.	GR24 strigolactone	0-13	taste receptor, type 2, member 124	Mus musculus	14-18
29479714-0	2018	Conversion of carlactone to carlactonoic acid is a conserved function of MAX1 homologs in strigolactone biosynthesis.	GR24 strigolactone	90-103	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	73-77
29550483-5	2018	We aimed to investigate the role of two SIRT1 activating plant-derived compounds, strigolactone analog GR24 and pinosylvin, in adipogenesis and inflammation of murine adipocytes.	GR24 strigolactone	82-95	sirtuin 1	Mus musculus	40-45
28643859-5	2017	It was shown that indeed strigolactone mimics prepared from GA3 and kaurenoic acid are active as stimulants when a D-ring is present; some of the mimics are as active as GR24.	GR24 strigolactone	25-38	succinyl-CoA:glutarate-CoA transferase	Homo sapiens	60-63
29545815-0	2018	Strigolactone Levels in Dicot Roots Are Determined by an Ancestral Symbiosis-Regulated Clade of the PHYTOENE SYNTHASE Gene Family.	GR24 strigolactone	0-13	MTR_8g469660	Medicago truncatula	100-117
29242624-0	2017	Plant-derived compounds strigolactone GR24 and pinosylvin activate SIRT1 and enhance glucose uptake in rat skeletal muscle cells.	GR24 strigolactone	24-37	sirtuin 1	Rattus norvegicus	67-72
29242624-4	2017	We hypothesised that the novel plant-derived compounds, strigolactone and pinosylvin, beneficially enhance SIRT1 function, insulin signalling, glucose uptake, and mitochondrial biogenesis in skeletal muscle cells.	GR24 strigolactone	56-69	sirtuin 1	Rattus norvegicus	107-112
29242624-8	2017	Strigolactone GR24 upregulated and activated SIRT1 without activating AMPK, enhanced insulin signalling, glucose uptake, GLUT4 translocation and mitochondrial biogenesis.	GR24 strigolactone	0-13	sirtuin 1	Rattus norvegicus	45-50
29242624-10	2017	The regulation of SIRT1 by strigolactone GR24 and the activation of AMPK by pinosylvin may offer novel therapeutic approaches in the treatment of insulin resistance in skeletal muscle.	GR24 strigolactone	27-40	sirtuin 1	Rattus norvegicus	18-23
28471323-6	2017	The expression levels of MAX1, MAX4, YUCCA8, YUCCA9, and BRC1, which are involved in auxin or strigolactone biosynthesis and responses, were lower in AcF plants than in wild-type plants.	GR24 strigolactone	94-107	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	25-29
28970845-0	2017	Comprehensive Analysis of DWARF14-LIKE2 (DLK2) Reveals Its Functional Divergence from Strigolactone-Related Paralogs.	GR24 strigolactone	86-99	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	26-39
28471323-6	2017	The expression levels of MAX1, MAX4, YUCCA8, YUCCA9, and BRC1, which are involved in auxin or strigolactone biosynthesis and responses, were lower in AcF plants than in wild-type plants.	GR24 strigolactone	94-107	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	31-35
28471323-6	2017	The expression levels of MAX1, MAX4, YUCCA8, YUCCA9, and BRC1, which are involved in auxin or strigolactone biosynthesis and responses, were lower in AcF plants than in wild-type plants.	GR24 strigolactone	94-107	Flavin-binding monooxygenase family protein	Arabidopsis thaliana	37-43
28471323-6	2017	The expression levels of MAX1, MAX4, YUCCA8, YUCCA9, and BRC1, which are involved in auxin or strigolactone biosynthesis and responses, were lower in AcF plants than in wild-type plants.	GR24 strigolactone	94-107	YUCCA 9	Arabidopsis thaliana	45-51
28471323-6	2017	The expression levels of MAX1, MAX4, YUCCA8, YUCCA9, and BRC1, which are involved in auxin or strigolactone biosynthesis and responses, were lower in AcF plants than in wild-type plants.	GR24 strigolactone	94-107	TCP family transcription factor	Arabidopsis thaliana	57-61
28289131-6	2017	Buds lacking BRC1 expression can remain inhibited and sensitive to inhibition by strigolactone.	GR24 strigolactone	81-94	TCP family transcription factor	Arabidopsis thaliana	13-17
28289131-9	2017	In the context of strigolactone-mediated bud regulation, our data suggest a coherent feed-forward loop in which strigolactone treatment reduces the probability of bud activation by parallel effects on BRC1 transcription and the shoot auxin transport network.	GR24 strigolactone	112-125	TCP family transcription factor	Arabidopsis thaliana	201-205
27662376-3	2016	Furthermore, the ABH fold serves as the core structure for phytohormone and ligand receptors in the gibberellin, strigolactone, and karrikin signaling pathways in plants.	GR24 strigolactone	113-126	alkB homolog 1, histone H2A dioxygenase	Homo sapiens	17-20
28392107-10	2017	By comparing protein stabilities, we show that SMXL3/4/5 proteins function differently to canonical strigolactone and karrikin signaling mediators, although being functionally interchangeable with those under low strigolactone/karrikin signaling conditions.	GR24 strigolactone	100-113	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	47-56
28392107-10	2017	By comparing protein stabilities, we show that SMXL3/4/5 proteins function differently to canonical strigolactone and karrikin signaling mediators, although being functionally interchangeable with those under low strigolactone/karrikin signaling conditions.	GR24 strigolactone	213-226	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	47-56
27748948-0	2017	Sl-IAA27 regulates strigolactone biosynthesis and mycorrhization in tomato (var.	GR24 strigolactone	19-32	auxin-responsive protein IAA27	Solanum lycopersicum	3-8
27748948-6	2017	Sl-IAA27-silencing resulted in down-regulation of three genes involved in strigolactone synthesis, NSP1, D27 and MAX1, and treatment of Sl-IAA27-silenced plants with the strigolactone analog GR24 complemented their mycorrhizal defect phenotype.	GR24 strigolactone	74-87	auxin-responsive protein IAA27	Solanum lycopersicum	3-8
27748948-6	2017	Sl-IAA27-silencing resulted in down-regulation of three genes involved in strigolactone synthesis, NSP1, D27 and MAX1, and treatment of Sl-IAA27-silenced plants with the strigolactone analog GR24 complemented their mycorrhizal defect phenotype.	GR24 strigolactone	170-183	auxin-responsive protein IAA27	Solanum lycopersicum	3-8
27748948-6	2017	Sl-IAA27-silencing resulted in down-regulation of three genes involved in strigolactone synthesis, NSP1, D27 and MAX1, and treatment of Sl-IAA27-silenced plants with the strigolactone analog GR24 complemented their mycorrhizal defect phenotype.	GR24 strigolactone	170-183	auxin-responsive protein IAA27	Solanum lycopersicum	139-144
27994609-3	2016	KAI2 is a homolog of DWARF 14 (D14), the receptor for endogenous strigolactone hormones.	GR24 strigolactone	65-78	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	0-4
27994609-3	2016	KAI2 is a homolog of DWARF 14 (D14), the receptor for endogenous strigolactone hormones.	GR24 strigolactone	65-78	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	21-29
27811075-6	2016	In contrast, the strigolactone biosynthetic enzyme AtCCD7 converted 9-cis-configured acyclic carotenes, such as 9-cis-zeta-carotene, 9"-cis-neurosporene, and 9-cis-lycopene, yielding 9-cis-configured products and indicating that AtCCD7, rather than AtCCD4, is the candidate for forming acyclic retrograde signals.	GR24 strigolactone	17-30	carotenoid cleavage dioxygenase 7	Arabidopsis thaliana	51-57
27909441-1	2016	MAX2 (MORE AXILLARY GROWTH2) is involved in diverse physiological processes, including photomorphogenesis, the abiotic stress response, as well as karrikin and strigolactone signaling-mediated shoot branching.	GR24 strigolactone	160-173	RNI-like superfamily protein	Arabidopsis thaliana	0-4
27811075-6	2016	In contrast, the strigolactone biosynthetic enzyme AtCCD7 converted 9-cis-configured acyclic carotenes, such as 9-cis-zeta-carotene, 9"-cis-neurosporene, and 9-cis-lycopene, yielding 9-cis-configured products and indicating that AtCCD7, rather than AtCCD4, is the candidate for forming acyclic retrograde signals.	GR24 strigolactone	17-30	carotenoid cleavage dioxygenase 7	Arabidopsis thaliana	229-235
27811075-6	2016	In contrast, the strigolactone biosynthetic enzyme AtCCD7 converted 9-cis-configured acyclic carotenes, such as 9-cis-zeta-carotene, 9"-cis-neurosporene, and 9-cis-lycopene, yielding 9-cis-configured products and indicating that AtCCD7, rather than AtCCD4, is the candidate for forming acyclic retrograde signals.	GR24 strigolactone	17-30	nine-cis-epoxycarotenoid dioxygenase 4	Arabidopsis thaliana	249-255
26760207-0	2016	Corrigendum: D14-SCF(D3)-dependent degradation of D53 regulates strigolactone signalling.	GR24 strigolactone	64-77	KIT ligand	Homo sapiens	17-20
27425246-1	2016	Previous studies in Arabidopsis reported that the MAX2 (more axillary growth 2) gene is a component of the strigolactone (SL) signaling pathway, which regulates a wide range of biological processes, from plant growth and development to environmental stress responses.	GR24 strigolactone	107-120	RNI-like superfamily protein	Arabidopsis thaliana	50-54
27425246-1	2016	Previous studies in Arabidopsis reported that the MAX2 (more axillary growth 2) gene is a component of the strigolactone (SL) signaling pathway, which regulates a wide range of biological processes, from plant growth and development to environmental stress responses.	GR24 strigolactone	107-120	RNI-like superfamily protein	Arabidopsis thaliana	56-78
27479325-5	2016	Notably, analyses of a highly branched Arabidopsis mutant d14-5 show that the AtD14(G158E) mutant maintains enzyme activity to hydrolyse strigolactone, but fails to efficiently interact with D3/MAX2 and loses the ability to act as a receptor that triggers strigolactone signalling in planta.	GR24 strigolactone	256-269	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	78-83
27479325-6	2016	These findings uncover a mechanism underlying the allosteric activation of AtD14 by strigolactone hydrolysis into CLIM, and define AtD14 as a non-canonical hormone receptor with dual functions to generate and sense the active form of strigolactone.	GR24 strigolactone	84-97	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	75-80
27479325-6	2016	These findings uncover a mechanism underlying the allosteric activation of AtD14 by strigolactone hydrolysis into CLIM, and define AtD14 as a non-canonical hormone receptor with dual functions to generate and sense the active form of strigolactone.	GR24 strigolactone	234-247	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	75-80
27479325-6	2016	These findings uncover a mechanism underlying the allosteric activation of AtD14 by strigolactone hydrolysis into CLIM, and define AtD14 as a non-canonical hormone receptor with dual functions to generate and sense the active form of strigolactone.	GR24 strigolactone	234-247	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	131-136
26883225-3	2016	D27 was previously proven to be involved in the strigolactone biosynthetic pathway in rice, Arabidopsis, and Medicago.	GR24 strigolactone	48-61	beta-carotene isomerase D27-like protein	Arabidopsis thaliana	0-3
27523280-0	2016	The Arabidopsis B-box protein BZS1/BBX20 interacts with HY5 and mediates strigolactone regulation of photomorphogenesis.	GR24 strigolactone	73-86	B-box zinc finger family protein	Arabidopsis thaliana	30-34
27523280-0	2016	The Arabidopsis B-box protein BZS1/BBX20 interacts with HY5 and mediates strigolactone regulation of photomorphogenesis.	GR24 strigolactone	73-86	B-box zinc finger family protein	Arabidopsis thaliana	35-40
27523280-8	2016	In contrast to BR, strigolactone (SL) increases BZS1 level, whereas the SL responses of hypocotyl elongation, chlorophyll and HY5 accumulation are diminished in the BZS1-SRDX seedlings, indicating that BZS1 is involved in these SL responses.	GR24 strigolactone	19-32	B-box zinc finger family protein	Arabidopsis thaliana	48-52
27523280-8	2016	In contrast to BR, strigolactone (SL) increases BZS1 level, whereas the SL responses of hypocotyl elongation, chlorophyll and HY5 accumulation are diminished in the BZS1-SRDX seedlings, indicating that BZS1 is involved in these SL responses.	GR24 strigolactone	19-32	B-box zinc finger family protein	Arabidopsis thaliana	165-169
27523280-8	2016	In contrast to BR, strigolactone (SL) increases BZS1 level, whereas the SL responses of hypocotyl elongation, chlorophyll and HY5 accumulation are diminished in the BZS1-SRDX seedlings, indicating that BZS1 is involved in these SL responses.	GR24 strigolactone	19-32	B-box zinc finger family protein	Arabidopsis thaliana	165-169
27479325-0	2016	DWARF14 is a non-canonical hormone receptor for strigolactone.	GR24 strigolactone	48-61	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	0-7
27479325-2	2016	The alpha/beta hydrolase DWARF14 (D14), which hydrolyses the plant branching hormone strigolactone and interacts with the F-box protein D3/MAX2, is probably involved in strigolactone detection.	GR24 strigolactone	85-98	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	25-32
27479325-2	2016	The alpha/beta hydrolase DWARF14 (D14), which hydrolyses the plant branching hormone strigolactone and interacts with the F-box protein D3/MAX2, is probably involved in strigolactone detection.	GR24 strigolactone	85-98	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	34-37
27479325-2	2016	The alpha/beta hydrolase DWARF14 (D14), which hydrolyses the plant branching hormone strigolactone and interacts with the F-box protein D3/MAX2, is probably involved in strigolactone detection.	GR24 strigolactone	85-98	RNI-like superfamily protein	Arabidopsis thaliana	139-143
27479325-2	2016	The alpha/beta hydrolase DWARF14 (D14), which hydrolyses the plant branching hormone strigolactone and interacts with the F-box protein D3/MAX2, is probably involved in strigolactone detection.	GR24 strigolactone	169-182	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	25-32
27479325-2	2016	The alpha/beta hydrolase DWARF14 (D14), which hydrolyses the plant branching hormone strigolactone and interacts with the F-box protein D3/MAX2, is probably involved in strigolactone detection.	GR24 strigolactone	169-182	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	34-37
27479325-2	2016	The alpha/beta hydrolase DWARF14 (D14), which hydrolyses the plant branching hormone strigolactone and interacts with the F-box protein D3/MAX2, is probably involved in strigolactone detection.	GR24 strigolactone	169-182	RNI-like superfamily protein	Arabidopsis thaliana	139-143
27479325-4	2016	Here we report the crystal structure of the strigolactone-induced AtD14-D3-ASK1 complex, reveal that Arabidopsis thaliana (At)D14 undergoes an open-to-closed state transition to trigger strigolactone signalling, and demonstrate that strigolactone is hydrolysed into a covalently linked intermediate molecule (CLIM) to initiate a conformational change of AtD14 to facilitate interaction with D3.	GR24 strigolactone	44-57	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	66-71
27479325-4	2016	Here we report the crystal structure of the strigolactone-induced AtD14-D3-ASK1 complex, reveal that Arabidopsis thaliana (At)D14 undergoes an open-to-closed state transition to trigger strigolactone signalling, and demonstrate that strigolactone is hydrolysed into a covalently linked intermediate molecule (CLIM) to initiate a conformational change of AtD14 to facilitate interaction with D3.	GR24 strigolactone	44-57	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	68-71
27479325-4	2016	Here we report the crystal structure of the strigolactone-induced AtD14-D3-ASK1 complex, reveal that Arabidopsis thaliana (At)D14 undergoes an open-to-closed state transition to trigger strigolactone signalling, and demonstrate that strigolactone is hydrolysed into a covalently linked intermediate molecule (CLIM) to initiate a conformational change of AtD14 to facilitate interaction with D3.	GR24 strigolactone	44-57	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	354-359
27479325-4	2016	Here we report the crystal structure of the strigolactone-induced AtD14-D3-ASK1 complex, reveal that Arabidopsis thaliana (At)D14 undergoes an open-to-closed state transition to trigger strigolactone signalling, and demonstrate that strigolactone is hydrolysed into a covalently linked intermediate molecule (CLIM) to initiate a conformational change of AtD14 to facilitate interaction with D3.	GR24 strigolactone	186-199	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	66-71
27479325-4	2016	Here we report the crystal structure of the strigolactone-induced AtD14-D3-ASK1 complex, reveal that Arabidopsis thaliana (At)D14 undergoes an open-to-closed state transition to trigger strigolactone signalling, and demonstrate that strigolactone is hydrolysed into a covalently linked intermediate molecule (CLIM) to initiate a conformational change of AtD14 to facilitate interaction with D3.	GR24 strigolactone	186-199	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	68-71
27479325-4	2016	Here we report the crystal structure of the strigolactone-induced AtD14-D3-ASK1 complex, reveal that Arabidopsis thaliana (At)D14 undergoes an open-to-closed state transition to trigger strigolactone signalling, and demonstrate that strigolactone is hydrolysed into a covalently linked intermediate molecule (CLIM) to initiate a conformational change of AtD14 to facilitate interaction with D3.	GR24 strigolactone	186-199	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	66-71
27479325-4	2016	Here we report the crystal structure of the strigolactone-induced AtD14-D3-ASK1 complex, reveal that Arabidopsis thaliana (At)D14 undergoes an open-to-closed state transition to trigger strigolactone signalling, and demonstrate that strigolactone is hydrolysed into a covalently linked intermediate molecule (CLIM) to initiate a conformational change of AtD14 to facilitate interaction with D3.	GR24 strigolactone	186-199	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	68-71
27479325-5	2016	Notably, analyses of a highly branched Arabidopsis mutant d14-5 show that the AtD14(G158E) mutant maintains enzyme activity to hydrolyse strigolactone, but fails to efficiently interact with D3/MAX2 and loses the ability to act as a receptor that triggers strigolactone signalling in planta.	GR24 strigolactone	137-150	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	78-83
27840586-0	2016	Strigolactone Analogues with a D-Ring Modified at C-2.	GR24 strigolactone	0-13	complement C2	Homo sapiens	50-53
26754282-1	2016	MAIN CONCLUSION: SMAX1 and SMXL2 control seedling growth, demonstrating functional redundancy within a gene family that mediates karrikin and strigolactone responses.	GR24 strigolactone	142-155	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	17-22
26754282-1	2016	MAIN CONCLUSION: SMAX1 and SMXL2 control seedling growth, demonstrating functional redundancy within a gene family that mediates karrikin and strigolactone responses.	GR24 strigolactone	142-155	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	27-32
26895334-1	2016	MAIN CONCLUSION: ZmCCD7/ZpCCD7 encodes a carotenoid cleavage dioxygenase that may mediate strigolactone biosynthesis highly responsive to phosphorus deficiency and undergoes negative selection over domestication from Zea ssp.	GR24 strigolactone	90-103	carotenoid cleavage dioxygenase	Zea mays	17-23
26895334-3	2016	Carotenoid cleavage dioxygenase 7 (CCD7) functions to suppress shoot branching by controlling strigolactone biosynthesis.	GR24 strigolactone	94-107	carotenoid cleavage dioxygenase	Zea mays	35-39
26895334-12	2016	Together with suppression of shoot branching in the max3 mutant by transformation of ZmCCD7/ZpCCD7, our work suggested that ZmCCD7/ZpCCD7 encodes a carotenoid cleavage dioxygenase mediating strigolactone biosynthesis in maize and its ancestor.	GR24 strigolactone	190-203	carotenoid cleavage dioxygenase	Zea mays	85-91
26895334-12	2016	Together with suppression of shoot branching in the max3 mutant by transformation of ZmCCD7/ZpCCD7, our work suggested that ZmCCD7/ZpCCD7 encodes a carotenoid cleavage dioxygenase mediating strigolactone biosynthesis in maize and its ancestor.	GR24 strigolactone	190-203	carotenoid cleavage dioxygenase	Zea mays	124-130
26760207-0	2016	Corrigendum: D14-SCF(D3)-dependent degradation of D53 regulates strigolactone signalling.	GR24 strigolactone	64-77	TPD52 like 1	Homo sapiens	50-53
26875827-3	2016	The strigolactone signal is perceived by a member of the alpha/beta-fold hydrolase superfamily, known as DWARF14 (D14).	GR24 strigolactone	4-17	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	114-117
26661110-6	2016	Lupin shoots suppress AM colonization in pea roots, in part by downregulating strigolactone exudation involving reduced expression of the strigolactone biosynthesis gene PsCCD8.	GR24 strigolactone	78-91	5'-nucleotidase, cytosolic IIIA	Homo sapiens	0-5
26661110-6	2016	Lupin shoots suppress AM colonization in pea roots, in part by downregulating strigolactone exudation involving reduced expression of the strigolactone biosynthesis gene PsCCD8.	GR24 strigolactone	138-151	5'-nucleotidase, cytosolic IIIA	Homo sapiens	0-5
26910887-0	2016	Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair.	GR24 strigolactone	35-48	collagen type XI alpha 2 chain	Homo sapiens	87-91
26546447-5	2015	SMXL7 is degraded rapidly after treatment with the synthetic strigolactone mixture rac-GR24.	GR24 strigolactone	61-74	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	0-5
26779242-0	2015	Evidence that KARRIKIN-INSENSITIVE2 (KAI2) Receptors may Perceive an Unknown Signal that is not Karrikin or Strigolactone.	GR24 strigolactone	108-121	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	14-35
26779242-0	2015	Evidence that KARRIKIN-INSENSITIVE2 (KAI2) Receptors may Perceive an Unknown Signal that is not Karrikin or Strigolactone.	GR24 strigolactone	108-121	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	37-41
26779242-5	2015	Recent studies of ligand-specificity among KAI2 paralogs in basal land plants and root parasitic plants suggest that karrikin and strigolactone perception may be evolutionary adaptations of KL receptors.	GR24 strigolactone	130-143	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	43-47
26546447-7	2015	Loss of SMXL6,7,8 suppresses several other strigolactone-related phenotypes in max2, including increased auxin transport and PIN1 accumulation, and increased lateral root density.	GR24 strigolactone	43-56	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	8-17
26546447-7	2015	Loss of SMXL6,7,8 suppresses several other strigolactone-related phenotypes in max2, including increased auxin transport and PIN1 accumulation, and increased lateral root density.	GR24 strigolactone	43-56	RNI-like superfamily protein	Arabidopsis thaliana	79-83
26546447-9	2015	Our data indicate that SMAX1 and SMXL6,7,8 repress karrikin and strigolactone signaling, respectively, and suggest that all MAX2-dependent growth effects are mediated by degradation of SMAX1/SMXL proteins.	GR24 strigolactone	64-77	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	23-28
26546447-9	2015	Our data indicate that SMAX1 and SMXL6,7,8 repress karrikin and strigolactone signaling, respectively, and suggest that all MAX2-dependent growth effects are mediated by degradation of SMAX1/SMXL proteins.	GR24 strigolactone	64-77	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	33-38
26546447-9	2015	Our data indicate that SMAX1 and SMXL6,7,8 repress karrikin and strigolactone signaling, respectively, and suggest that all MAX2-dependent growth effects are mediated by degradation of SMAX1/SMXL proteins.	GR24 strigolactone	64-77	RNI-like superfamily protein	Arabidopsis thaliana	124-128
26257333-0	2015	Biochemical characterization and selective inhibition of beta-carotene cis-trans isomerase D27 and carotenoid cleavage dioxygenase CCD8 on the strigolactone biosynthetic pathway.	GR24 strigolactone	143-156	beta-carotene isomerase D27-like protein	Arabidopsis thaliana	91-94
26257333-0	2015	Biochemical characterization and selective inhibition of beta-carotene cis-trans isomerase D27 and carotenoid cleavage dioxygenase CCD8 on the strigolactone biosynthetic pathway.	GR24 strigolactone	143-156	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	131-135
26257333-1	2015	The first three enzymatic steps of the strigolactone biosynthetic pathway catalysed by beta-carotene cis-trans isomerase Dwarf27 (D27) from Oryza sativa and carotenoid cleavage dioxygenases CCD7 and CCD8 from Arabidopsis thaliana have been reconstituted in vitro, and kinetic assays have been developed for each enzyme, in order to develop selective enzyme inhibitors.	GR24 strigolactone	39-52	beta-carotene isomerase D27-like protein	Arabidopsis thaliana	130-133
26257333-1	2015	The first three enzymatic steps of the strigolactone biosynthetic pathway catalysed by beta-carotene cis-trans isomerase Dwarf27 (D27) from Oryza sativa and carotenoid cleavage dioxygenases CCD7 and CCD8 from Arabidopsis thaliana have been reconstituted in vitro, and kinetic assays have been developed for each enzyme, in order to develop selective enzyme inhibitors.	GR24 strigolactone	39-52	carotenoid cleavage dioxygenase 7	Arabidopsis thaliana	190-194
26257333-1	2015	The first three enzymatic steps of the strigolactone biosynthetic pathway catalysed by beta-carotene cis-trans isomerase Dwarf27 (D27) from Oryza sativa and carotenoid cleavage dioxygenases CCD7 and CCD8 from Arabidopsis thaliana have been reconstituted in vitro, and kinetic assays have been developed for each enzyme, in order to develop selective enzyme inhibitors.	GR24 strigolactone	39-52	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	199-203
25979917-6	2015	The strigolactone biosynthesis genes MORE AXIALLY GROWTH3 (MAX3) and MAX4 were drastically induced during dark incubation and treatment with the senescence-promoting phytohormone ethylene, suggesting that strigolactone is synthesized in the leaf during leaf senescence.	GR24 strigolactone	4-17	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	69-73
25979917-6	2015	The strigolactone biosynthesis genes MORE AXIALLY GROWTH3 (MAX3) and MAX4 were drastically induced during dark incubation and treatment with the senescence-promoting phytohormone ethylene, suggesting that strigolactone is synthesized in the leaf during leaf senescence.	GR24 strigolactone	205-218	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	69-73
25344813-0	2014	Rice cytochrome P450 MAX1 homologs catalyze distinct steps in strigolactone biosynthesis.	GR24 strigolactone	62-75	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	21-25
26228149-8	2015	KAI2d transgenes confer strigolactone-specific germination responses to Arabidopsis thaliana.	GR24 strigolactone	24-37	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	0-4
26228149-9	2015	Thus, the KAI2 paralogs D14 and KAI2d underwent convergent evolution of strigolactone recognition, respectively enabling developmental responses to strigolactones in angiosperms and host detection in parasites.	GR24 strigolactone	72-85	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	10-14
26228149-9	2015	Thus, the KAI2 paralogs D14 and KAI2d underwent convergent evolution of strigolactone recognition, respectively enabling developmental responses to strigolactones in angiosperms and host detection in parasites.	GR24 strigolactone	72-85	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	24-27
25849639-2	2015	MAX2 appears essential for the perception of the newly characterized phytohormone strigolactone, a negative regulator of polar auxin transport in Arabidopsis.	GR24 strigolactone	82-95	RNI-like superfamily protein	Arabidopsis thaliana	0-4
25179782-2	2014	Although only recently identified, rapid progress has been made in understanding strigolactone biology, including the identification of a signalling pathway involving DWARF14 alpha/beta-fold proteins, the SCF(MAX2) ubiquitin ligase and SMAX1-LIKE (SMXL) family of chaperonin-like proteins.	GR24 strigolactone	81-94	KIT ligand	Homo sapiens	205-208
25179782-2	2014	Although only recently identified, rapid progress has been made in understanding strigolactone biology, including the identification of a signalling pathway involving DWARF14 alpha/beta-fold proteins, the SCF(MAX2) ubiquitin ligase and SMAX1-LIKE (SMXL) family of chaperonin-like proteins.	GR24 strigolactone	81-94	androgen receptor	Homo sapiens	236-246
25179782-3	2014	Several rapid effects of strigolactone signalling have also been identified, including endocytosis of the PIN-FORMED1 (PIN1) auxin efflux carrier and transcript accumulation of the BRANCHED1 (BRC1) transcription factor.	GR24 strigolactone	25-38	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	Homo sapiens	106-117
25179782-3	2014	Several rapid effects of strigolactone signalling have also been identified, including endocytosis of the PIN-FORMED1 (PIN1) auxin efflux carrier and transcript accumulation of the BRANCHED1 (BRC1) transcription factor.	GR24 strigolactone	25-38	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	Homo sapiens	119-123
24996032-1	2014	Strigolactone (SL) and karrikin (KAR) signalling control many aspects of plant growth and development through similar mechanisms employing related alpha/beta-fold hydrolase-receptors and a common F-box protein named MORE AXILARY GROWTH2 (MAX2) in Arabidopsis or DWARF3 (D3) in rice.	GR24 strigolactone	0-13	RNI-like superfamily protein	Arabidopsis thaliana	216-236
25414720-5	2014	Although the SL biosynthetic pathway is not fully understood, it has been demonstrated that beta-carotene isomerases, carotenoid cleavage dioxygenases (CCDs), and a cytochrome P450 monooxygenase are involved in strigolactone biosynthesis.	GR24 strigolactone	211-224	abscisic acid 8'-hydroxylase 4-like	Nicotiana tabacum	165-194
24996032-1	2014	Strigolactone (SL) and karrikin (KAR) signalling control many aspects of plant growth and development through similar mechanisms employing related alpha/beta-fold hydrolase-receptors and a common F-box protein named MORE AXILARY GROWTH2 (MAX2) in Arabidopsis or DWARF3 (D3) in rice.	GR24 strigolactone	0-13	RNI-like superfamily protein	Arabidopsis thaliana	238-242
24996032-1	2014	Strigolactone (SL) and karrikin (KAR) signalling control many aspects of plant growth and development through similar mechanisms employing related alpha/beta-fold hydrolase-receptors and a common F-box protein named MORE AXILARY GROWTH2 (MAX2) in Arabidopsis or DWARF3 (D3) in rice.	GR24 strigolactone	0-13	Cytochrome P450 superfamily protein	Arabidopsis thaliana	262-268
24433542-7	2014	As the karrikin and strigolactone response mechanisms are so similar, it is speculated that the endogenous signalling compound for the KAI2 system may be a specific strigolactone.	GR24 strigolactone	20-33	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	135-139
25126711-0	2014	Detection of parasitic plant suicide germination compounds using a high-throughput Arabidopsis HTL/KAI2 strigolactone perception system.	GR24 strigolactone	104-117	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	99-103
25126711-2	2014	Here we show that an active enantiomer form of the strigolactone GR24, the germination stimulant karrikin, and a number of structurally related small molecules called cotylimides all bind the HTL/KAI2 alpha/beta hydrolase in Arabidopsis.	GR24 strigolactone	51-64	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	196-200
24433542-7	2014	As the karrikin and strigolactone response mechanisms are so similar, it is speculated that the endogenous signalling compound for the KAI2 system may be a specific strigolactone.	GR24 strigolactone	165-178	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	135-139
24433542-9	2014	Structural studies of KAI2 protein and its interaction with karrikins and strigolactone analogues provide some insight into possible protein-ligand interactions, but are hampered by lack of knowledge of the endogenous ligand.	GR24 strigolactone	74-87	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	22-26
24571327-0	2014	Strigolactone analog GR24 triggers changes in PIN2 polarity, vesicle trafficking and actin filament architecture.	GR24 strigolactone	0-13	Auxin efflux carrier family protein	Arabidopsis thaliana	46-50
25036388-3	2014	In the model plant Arabidopsis, MORE AXILLARY GROWTH1 (MAX1), MAX2, MAX3 and MAX4 are four founding members of strigolactone pathway genes.	GR24 strigolactone	111-124	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	32-53
25036388-3	2014	In the model plant Arabidopsis, MORE AXILLARY GROWTH1 (MAX1), MAX2, MAX3 and MAX4 are four founding members of strigolactone pathway genes.	GR24 strigolactone	111-124	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	55-59
25036388-3	2014	In the model plant Arabidopsis, MORE AXILLARY GROWTH1 (MAX1), MAX2, MAX3 and MAX4 are four founding members of strigolactone pathway genes.	GR24 strigolactone	111-124	RNI-like superfamily protein	Arabidopsis thaliana	62-66
25036388-3	2014	In the model plant Arabidopsis, MORE AXILLARY GROWTH1 (MAX1), MAX2, MAX3 and MAX4 are four founding members of strigolactone pathway genes.	GR24 strigolactone	111-124	carotenoid cleavage dioxygenase 7	Arabidopsis thaliana	68-72
25036388-3	2014	In the model plant Arabidopsis, MORE AXILLARY GROWTH1 (MAX1), MAX2, MAX3 and MAX4 are four founding members of strigolactone pathway genes.	GR24 strigolactone	111-124	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	77-81
24571327-0	2014	Strigolactone analog GR24 triggers changes in PIN2 polarity, vesicle trafficking and actin filament architecture.	GR24 strigolactone	0-13	actin-12	Arabidopsis thaliana	85-90
24483232-6	2014	ShMAX2, the Striga ortholog of Arabidopsis MORE AXILLARY BRANCHING 2 (AtMAX2) - which mediates strigolactone signaling - complements several of the Arabidopsis max2-1 phenotypes, including the root and shoot phenotype, the High Irradiance Response and the response to strigolactones.	GR24 strigolactone	95-108	RNI-like superfamily protein	Arabidopsis thaliana	70-76
24569131-0	2014	D53: the missing link in strigolactone signaling.	GR24 strigolactone	25-38	TPD52 like 1	Homo sapiens	0-3
24685691-3	2014	CCD8 converts this intermediate through a combination of yet undetermined reactions into the strigolactone-like compound carlactone.	GR24 strigolactone	93-106	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	0-4
24483232-6	2014	ShMAX2, the Striga ortholog of Arabidopsis MORE AXILLARY BRANCHING 2 (AtMAX2) - which mediates strigolactone signaling - complements several of the Arabidopsis max2-1 phenotypes, including the root and shoot phenotype, the High Irradiance Response and the response to strigolactones.	GR24 strigolactone	95-108	RNI-like superfamily protein	Arabidopsis thaliana	160-164
24126495-6	2014	The photoreceptor mutants cry1 cry2, phyA, and phyB are hyposensitive to strigolactone analog GR24 under the respective monochromatic light conditions, while cop1 and pif1 pif3 pif4 pif5 (pifq) quadruple mutants are hypersensitive to GR24 in darkness.	GR24 strigolactone	73-86	cryptochrome 1	Arabidopsis thaliana	26-30
24742967-0	2014	Strigolactone analogues induce apoptosis through activation of p38 and the stress response pathway in cancer cell lines and in conditionally reprogrammed primary prostate cancer cells.	GR24 strigolactone	0-13	mitogen-activated protein kinase 14	Homo sapiens	63-66
24742967-4	2014	Treatment of cancer cells with strigolactone analogues was hallmarked by activation of the stress-related MAPKs: p38 and JNK and induction of stress-related genes; cell cycle arrest and apoptosis evident by increased percentages of cells in the sub-G1 fraction and Annexin V staining.	GR24 strigolactone	31-44	mitogen-activated protein kinase 14	Homo sapiens	113-116
24742967-4	2014	Treatment of cancer cells with strigolactone analogues was hallmarked by activation of the stress-related MAPKs: p38 and JNK and induction of stress-related genes; cell cycle arrest and apoptosis evident by increased percentages of cells in the sub-G1 fraction and Annexin V staining.	GR24 strigolactone	31-44	mitogen-activated protein kinase 8	Homo sapiens	121-124
24126495-6	2014	The photoreceptor mutants cry1 cry2, phyA, and phyB are hyposensitive to strigolactone analog GR24 under the respective monochromatic light conditions, while cop1 and pif1 pif3 pif4 pif5 (pifq) quadruple mutants are hypersensitive to GR24 in darkness.	GR24 strigolactone	73-86	cryptochrome 2	Arabidopsis thaliana	31-35
24126495-9	2014	These results suggest that the light dependency of strigolactone regulation of hypocotyl elongation is likely mediated through MAX2-dependent promotion of HY5 expression, light-dependent accumulation of HY5, and PIF-regulated components.	GR24 strigolactone	51-64	RNI-like superfamily protein	Arabidopsis thaliana	127-131
24126495-9	2014	These results suggest that the light dependency of strigolactone regulation of hypocotyl elongation is likely mediated through MAX2-dependent promotion of HY5 expression, light-dependent accumulation of HY5, and PIF-regulated components.	GR24 strigolactone	51-64	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	155-158
24126495-9	2014	These results suggest that the light dependency of strigolactone regulation of hypocotyl elongation is likely mediated through MAX2-dependent promotion of HY5 expression, light-dependent accumulation of HY5, and PIF-regulated components.	GR24 strigolactone	51-64	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	203-206
24464483-0	2014	Natural variation of rice strigolactone biosynthesis is associated with the deletion of two MAX1 orthologs.	GR24 strigolactone	26-39	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	92-96
24610723-0	2014	Strigolactone promotes degradation of DWARF14, an alpha/beta hydrolase essential for strigolactone signaling in Arabidopsis.	GR24 strigolactone	0-13	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	38-45
24610723-0	2014	Strigolactone promotes degradation of DWARF14, an alpha/beta hydrolase essential for strigolactone signaling in Arabidopsis.	GR24 strigolactone	85-98	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	38-45
23893171-1	2013	Abiotic chemical signals discovered in smoke that are known as karrikins (KARs) and the endogenous hormone strigolactone (SL) control plant growth through a shared MORE AXILLARY GROWTH2 (MAX2)-dependent pathway.	GR24 strigolactone	107-120	RNI-like superfamily protein	Arabidopsis thaliana	164-185
24705023-5	2014	NSP1 has been implicated in a strigolactone biosynthesis gene DWARF27 expression.	GR24 strigolactone	30-43	Protein NODULATION SIGNALING PATHWAY 1	Lotus japonicus	0-4
24705023-6	2014	Nevertheless, in nsp1, DWARF27 was induced by inoculation with AM fungi, implying the existence of a NSP1-independent regulatory mechanism of strigolactone biosynthesis during AMS establishment.	GR24 strigolactone	142-155	Protein NODULATION SIGNALING PATHWAY 1	Lotus japonicus	17-21
23773129-3	2013	Here, we report the chemical synthesis of the strigolactone precursor carlactone, and show that it represses Arabidopsis shoot branching and influences leaf morphogenesis via a mechanism that is dependent on the cytochrome P450 MAX1.	GR24 strigolactone	46-59	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	228-232
24198318-11	2014	Interestingly, ABA, osmotic stress, and drought-sensitive phenotypes were restricted to max2, and the strigolactone biosynthetic pathway mutants max1, max3, and max4 did not display any defects in these responses.	GR24 strigolactone	102-115	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	145-149
24198318-11	2014	Interestingly, ABA, osmotic stress, and drought-sensitive phenotypes were restricted to max2, and the strigolactone biosynthetic pathway mutants max1, max3, and max4 did not display any defects in these responses.	GR24 strigolactone	102-115	carotenoid cleavage dioxygenase 7	Arabidopsis thaliana	151-155
24198318-11	2014	Interestingly, ABA, osmotic stress, and drought-sensitive phenotypes were restricted to max2, and the strigolactone biosynthetic pathway mutants max1, max3, and max4 did not display any defects in these responses.	GR24 strigolactone	102-115	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	161-165
23773129-1	2013	Strigolactone hormones are derived from carotenoids via carlactone, and act through the alpha/beta-hydrolase D14 and the F-box protein D3/MAX2 to repress plant shoot branching.	GR24 strigolactone	0-13	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	109-112
23773129-1	2013	Strigolactone hormones are derived from carotenoids via carlactone, and act through the alpha/beta-hydrolase D14 and the F-box protein D3/MAX2 to repress plant shoot branching.	GR24 strigolactone	0-13	RNI-like superfamily protein	Arabidopsis thaliana	138-142
23893171-1	2013	Abiotic chemical signals discovered in smoke that are known as karrikins (KARs) and the endogenous hormone strigolactone (SL) control plant growth through a shared MORE AXILLARY GROWTH2 (MAX2)-dependent pathway.	GR24 strigolactone	107-120	RNI-like superfamily protein	Arabidopsis thaliana	187-191
23666055-8	2013	Furthermore, transcription levels of CCD7 and CCD8, key genes for the strigolactone pathway, highly increased during ABA treatment providing further evidence that ABA is involved in regulating strigolactone metabolism.	GR24 strigolactone	70-83	carotenoid cleavage dioxygenase 7	Glycine max	37-41
23666055-8	2013	Furthermore, transcription levels of CCD7 and CCD8, key genes for the strigolactone pathway, highly increased during ABA treatment providing further evidence that ABA is involved in regulating strigolactone metabolism.	GR24 strigolactone	70-83	carotenoid cleavage dioxygenase	Glycine max	46-50
23666055-8	2013	Furthermore, transcription levels of CCD7 and CCD8, key genes for the strigolactone pathway, highly increased during ABA treatment providing further evidence that ABA is involved in regulating strigolactone metabolism.	GR24 strigolactone	193-206	carotenoid cleavage dioxygenase 7	Glycine max	37-41
23666055-8	2013	Furthermore, transcription levels of CCD7 and CCD8, key genes for the strigolactone pathway, highly increased during ABA treatment providing further evidence that ABA is involved in regulating strigolactone metabolism.	GR24 strigolactone	193-206	carotenoid cleavage dioxygenase	Glycine max	46-50
23382651-0	2013	Strigolactone can promote or inhibit shoot branching by triggering rapid depletion of the auxin efflux protein PIN1 from the plasma membrane.	GR24 strigolactone	0-13	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	Homo sapiens	111-115
23302095-1	2013	MORE AXILLARY BRANCHING 2 (MAX2), initially identified in Arabidopsis thaliana, is a key regulatory gene in strigolactone signal transduction.	GR24 strigolactone	108-121	RNI-like superfamily protein	Arabidopsis thaliana	0-25
23302095-1	2013	MORE AXILLARY BRANCHING 2 (MAX2), initially identified in Arabidopsis thaliana, is a key regulatory gene in strigolactone signal transduction.	GR24 strigolactone	108-121	RNI-like superfamily protein	Arabidopsis thaliana	27-31
23425316-0	2013	Strigolactone signaling in the endodermis is sufficient to restore root responses and involves SHORT HYPOCOTYL 2 (SHY2) activity.	GR24 strigolactone	0-13	AUX/IAA transcriptional regulator family protein	Arabidopsis thaliana	114-118
23425316-0	2013	Strigolactone signaling in the endodermis is sufficient to restore root responses and involves SHORT HYPOCOTYL 2 (SHY2) activity.	GR24 strigolactone	0-13	AUX/IAA transcriptional regulator family protein	Arabidopsis thaliana	95-112
23382651-6	2013	A computational model in which strigolactone action is represented as an increase in the rate of removal of the auxin export protein, PIN1, from the plasma membrane can reproduce both the auxin transport and shoot branching phenotypes observed in various mutant combinations and strigolactone treatments, including the counterintuitive ability of strigolactones either to promote or inhibit shoot branching, depending on the auxin transport status of the plant.	GR24 strigolactone	31-44	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	Homo sapiens	134-138
23382651-6	2013	A computational model in which strigolactone action is represented as an increase in the rate of removal of the auxin export protein, PIN1, from the plasma membrane can reproduce both the auxin transport and shoot branching phenotypes observed in various mutant combinations and strigolactone treatments, including the counterintuitive ability of strigolactones either to promote or inhibit shoot branching, depending on the auxin transport status of the plant.	GR24 strigolactone	279-292	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	Homo sapiens	134-138
23382651-7	2013	Consistent with this predicted mode of action, strigolactone signalling was found to trigger PIN1 depletion from the plasma membrane of xylem parenchyma cells in the stem.	GR24 strigolactone	47-60	peptidylprolyl cis/trans isomerase, NIMA-interacting 1	Homo sapiens	93-97
23349965-7	2013	The structure of KAI2 is consistent with its designation as a serine hydrolase, as well as previous data implicating the protein in karrikin and strigolactone signalling.	GR24 strigolactone	145-158	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	17-21
22540368-4	2012	New fhy3 alleles were isolated as suppressors of max2-1 (more axillary branching2-1), a strigolactone-insensitive mutant characterised by highly branched shoots.	GR24 strigolactone	88-101	far-red elongated hypocotyls 3	Arabidopsis thaliana	4-8
22414435-10	2012	Furthermore, both wild-type and strigolactone biosynthesis mutants of Arabidopsis thaliana Atccd7 and Atccd8 induced similar levels of P. ramosa seed germination, suggesting that compounds other than strigolactone function as germination stimulants for P. ramosa in other Brassicaceae spp.	GR24 strigolactone	32-45	carotenoid cleavage dioxygenase 7	Arabidopsis thaliana	91-97
22414435-10	2012	Furthermore, both wild-type and strigolactone biosynthesis mutants of Arabidopsis thaliana Atccd7 and Atccd8 induced similar levels of P. ramosa seed germination, suggesting that compounds other than strigolactone function as germination stimulants for P. ramosa in other Brassicaceae spp.	GR24 strigolactone	32-45	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	102-108
22414435-10	2012	Furthermore, both wild-type and strigolactone biosynthesis mutants of Arabidopsis thaliana Atccd7 and Atccd8 induced similar levels of P. ramosa seed germination, suggesting that compounds other than strigolactone function as germination stimulants for P. ramosa in other Brassicaceae spp.	GR24 strigolactone	200-213	carotenoid cleavage dioxygenase 7	Arabidopsis thaliana	91-97
22323776-4	2012	CYCLIN B1 expression, an early marker for the initiation of adventitious root primordia in Arabidopsis, is enhanced in more axillary growth2 (max2), a strigolactone response mutant, suggesting that strigolactones restrain the number of adventitious roots by inhibiting the very first formative divisions of the founder cells.	GR24 strigolactone	151-164	cyclin B1	Arabidopsis thaliana	0-9
22516816-0	2012	HY5 is involved in strigolactone-dependent seed germination in Arabidopsis.	GR24 strigolactone	19-32	Basic-leucine zipper (bZIP) transcription factor family protein	Arabidopsis thaliana	0-3
22357928-5	2012	In rice, the DWARF14 protein is required for strigolactone-dependent inhibition of shoot branching.	GR24 strigolactone	45-58	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	13-20
22357928-6	2012	Here, we show that the Arabidopsis DWARF14 orthologue, AtD14, is also necessary for normal strigolactone responses in seedlings and adult plants.	GR24 strigolactone	91-104	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	35-42
22357928-6	2012	Here, we show that the Arabidopsis DWARF14 orthologue, AtD14, is also necessary for normal strigolactone responses in seedlings and adult plants.	GR24 strigolactone	91-104	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	55-60
22357928-10	2012	We propose that AtD14 and KAI2 define a class of proteins that permit the separate regulation of karrikin and strigolactone signalling by MAX2.	GR24 strigolactone	110-123	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	16-21
22357928-10	2012	We propose that AtD14 and KAI2 define a class of proteins that permit the separate regulation of karrikin and strigolactone signalling by MAX2.	GR24 strigolactone	110-123	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	26-30
22357928-10	2012	We propose that AtD14 and KAI2 define a class of proteins that permit the separate regulation of karrikin and strigolactone signalling by MAX2.	GR24 strigolactone	110-123	RNI-like superfamily protein	Arabidopsis thaliana	138-142
22323776-4	2012	CYCLIN B1 expression, an early marker for the initiation of adventitious root primordia in Arabidopsis, is enhanced in more axillary growth2 (max2), a strigolactone response mutant, suggesting that strigolactones restrain the number of adventitious roots by inhibiting the very first formative divisions of the founder cells.	GR24 strigolactone	151-164	RNI-like superfamily protein	Arabidopsis thaliana	142-146
21555559-0	2011	F-box protein MAX2 has dual roles in karrikin and strigolactone signaling in Arabidopsis thaliana.	GR24 strigolactone	50-63	RNI-like superfamily protein	Arabidopsis thaliana	14-18
22404467-7	2012	They are active in species not normally associated with fire, and in Arabidopsis they require the F-box protein MAX2, which also controls responses to strigolactone hormones.	GR24 strigolactone	151-164	RNI-like superfamily protein	Arabidopsis thaliana	112-116
21706088-0	2011	Synthetic studies on the solanacol ABC ring system by cation-initiated cascade cyclization: implications for strigolactone biosynthesis.	GR24 strigolactone	109-122	ATP binding cassette subfamily B member 6 (Langereis blood group)	Homo sapiens	35-38
21555559-3	2011	A genetic screen for karrikin-insensitive mutants in Arabidopsis thaliana revealed that karrikin signaling requires the F-box protein MAX2, which also mediates responses to the structurally-related strigolactone family of phytohormones.	GR24 strigolactone	198-211	RNI-like superfamily protein	Arabidopsis thaliana	134-138
21555559-5	2011	Karrikins also repress MAX4 and IAA1 transcripts, which show negative feedback regulation by strigolactone.	GR24 strigolactone	93-106	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	23-27
21555559-5	2011	Karrikins also repress MAX4 and IAA1 transcripts, which show negative feedback regulation by strigolactone.	GR24 strigolactone	93-106	indole-3-acetic acid inducible	Arabidopsis thaliana	32-36
21119045-6	2011	We show that at least one of them (orobanchol) is strongly reduced in the putative strigolactone biosynthetic mutants more axillary growth1 (max1) and max4 but not in the signal transduction mutant max2.	GR24 strigolactone	83-96	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	141-145
21119045-6	2011	We show that at least one of them (orobanchol) is strongly reduced in the putative strigolactone biosynthetic mutants more axillary growth1 (max1) and max4 but not in the signal transduction mutant max2.	GR24 strigolactone	83-96	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	151-155
22174848-10	2011	We propose that the developmental defects observed in the ppd5 mutants are related to a deficiency in strigolactone biosynthesis.	GR24 strigolactone	102-115	PsbP domain protein (Mog1/PsbP/DUF1795-like photosystem II reaction center PsbP family protein)	Arabidopsis thaliana	58-62
19641034-1	2009	In Arabidopsis (Arabidopsis thaliana), the carotenoid cleavage dioxygenases MORE AXILLARY GROWTH3 (MAX3) and MAX4 act together with MAX1 to produce a strigolactone signaling molecule required for the inhibition of axillary bud outgrowth.	GR24 strigolactone	150-163	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	109-113
20194924-6	2010	Accordingly, the transcription level of a key enzyme (CCD7) putatively involved in strigolactone synthesis in tomato was reduced in Sl-ORT1 compared with the wild type (WT).	GR24 strigolactone	83-96	carotenoid cleavage dioxygenase 7	Solanum lycopersicum	54-58
19845881-0	2010	SlCCD7 controls strigolactone biosynthesis, shoot branching and mycorrhiza-induced apocarotenoid formation in tomato.	GR24 strigolactone	16-29	carotenoid cleavage dioxygenase 7	Solanum lycopersicum	0-6
19845881-3	2010	Two of the genes within this pathway, MAX3/CCD7 and MAX4/CCD8, encode carotenoid cleavage enzymes involved in generating a branch-inhibiting hormone, recently identified as strigolactone.	GR24 strigolactone	173-186	carotenoid cleavage dioxygenase 7	Solanum lycopersicum	43-47
19845881-14	2010	This work demonstrates the diverse roles of MAX3/CCD7 in strigolactone production, shoot branching, source-sink interactions and production of arbuscular mycorrhiza-induced apocarotenoids.	GR24 strigolactone	57-70	carotenoid cleavage dioxygenase 7	Solanum lycopersicum	49-53
20667910-2	2010	Here we show that the branching phenotype of mutants in the Arabidopsis P450 family member, MAX1, can be fully rescued by strigolactone addition, suggesting that MAX1 acts in SL synthesis.	GR24 strigolactone	122-135	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	92-96
20667910-2	2010	Here we show that the branching phenotype of mutants in the Arabidopsis P450 family member, MAX1, can be fully rescued by strigolactone addition, suggesting that MAX1 acts in SL synthesis.	GR24 strigolactone	122-135	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	162-166
19641034-1	2009	In Arabidopsis (Arabidopsis thaliana), the carotenoid cleavage dioxygenases MORE AXILLARY GROWTH3 (MAX3) and MAX4 act together with MAX1 to produce a strigolactone signaling molecule required for the inhibition of axillary bud outgrowth.	GR24 strigolactone	150-163	cytochrome P450, family 711, subfamily A, polypeptide 1	Arabidopsis thaliana	132-136
18690209-3	2008	Here we present evidence that carotenoid cleavage dioxygenase 8 shoot branching mutants of pea are strigolactone deficient and that strigolactone application restores the wild-type branching phenotype to ccd8 mutants.	GR24 strigolactone	132-145	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	204-208
34839530-4	2022	The results show that shoot phytochrome B (phyB) triggers shoot-derived mobile ELONGATED HYPOCOTYL5 (HY5) protein accumulation in roots, and HY5 further positively regulates transcription of strigolactone (SL) synthetic genes, thus forming a shoot phyB-dependent systemic signaling pathway that regulates the synthesis and accumulation of SLs in roots.	GR24 strigolactone	191-204	phytochrome B2	Solanum lycopersicum	28-41
35406919-6	2022	Significantly, MsD14 could physically interact with AtMAX2 and MsMAX2 in the presence of strigolactone, suggesting a similarity between MsD14 and AtD14.	GR24 strigolactone	89-102	RNI-like superfamily protein	Arabidopsis thaliana	52-58
34498760-3	2021	As klu mutants display not only a short plastochron but also a branching phenotype reminiscent of strigolactone (SL) mutants, we investigated whether KLU/CYP78A5 is involved in SL biosynthesis.	GR24 strigolactone	98-111	cytochrome P450, family 78, subfamily A, polypeptide 5	Arabidopsis thaliana	150-153
34719688-5	2021	Strigolactone-mediated heat and cold tolerance was associated with the induction of abscisic acid (ABA), heat shock protein 70 (HSP70) accumulation, C-REPEAT BINDING FACTOR 1 (CBF1) transcription, and antioxidant enzyme activity.	GR24 strigolactone	0-13	heat shock protein 70	Solanum lycopersicum	105-126
34719688-5	2021	Strigolactone-mediated heat and cold tolerance was associated with the induction of abscisic acid (ABA), heat shock protein 70 (HSP70) accumulation, C-REPEAT BINDING FACTOR 1 (CBF1) transcription, and antioxidant enzyme activity.	GR24 strigolactone	0-13	heat shock protein 70	Solanum lycopersicum	128-133
34719688-5	2021	Strigolactone-mediated heat and cold tolerance was associated with the induction of abscisic acid (ABA), heat shock protein 70 (HSP70) accumulation, C-REPEAT BINDING FACTOR 1 (CBF1) transcription, and antioxidant enzyme activity.	GR24 strigolactone	0-13	C-repeat-binding factor-1	Solanum lycopersicum	149-174
34719688-5	2021	Strigolactone-mediated heat and cold tolerance was associated with the induction of abscisic acid (ABA), heat shock protein 70 (HSP70) accumulation, C-REPEAT BINDING FACTOR 1 (CBF1) transcription, and antioxidant enzyme activity.	GR24 strigolactone	0-13	C-repeat-binding factor-1	Solanum lycopersicum	176-180
34245626-1	2021	DWARF53 (D53) in rice (Oryza sativa) and its homologs in Arabidopsis (Arabidopsis thaliana), SUPPRESSOR OF MAX2-LIKE 6 (SMXL6), SMXL7 and SMXL8, are well established negative regulators of strigolactone signalling involved in shoot branching.	GR24 strigolactone	189-202	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	93-118
34245626-1	2021	DWARF53 (D53) in rice (Oryza sativa) and its homologs in Arabidopsis (Arabidopsis thaliana), SUPPRESSOR OF MAX2-LIKE 6 (SMXL6), SMXL7 and SMXL8, are well established negative regulators of strigolactone signalling involved in shoot branching.	GR24 strigolactone	189-202	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	120-125
34245626-1	2021	DWARF53 (D53) in rice (Oryza sativa) and its homologs in Arabidopsis (Arabidopsis thaliana), SUPPRESSOR OF MAX2-LIKE 6 (SMXL6), SMXL7 and SMXL8, are well established negative regulators of strigolactone signalling involved in shoot branching.	GR24 strigolactone	189-202	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	128-133
34245626-1	2021	DWARF53 (D53) in rice (Oryza sativa) and its homologs in Arabidopsis (Arabidopsis thaliana), SUPPRESSOR OF MAX2-LIKE 6 (SMXL6), SMXL7 and SMXL8, are well established negative regulators of strigolactone signalling involved in shoot branching.	GR24 strigolactone	189-202	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	138-143
35563637-5	2022	However, the amount of endogenous salicylic acid and the expression levels of salicylic acid-responsive genes were lower in strigolactone signaling-deficient max2 mutants than in wildtype plants.	GR24 strigolactone	124-137	RNI-like superfamily protein	Arabidopsis thaliana	158-162
35192364-7	2022	Furthermore, activation differences between strigolactone receptor in Striga, ShHTL7, and AtD14 could contribute to the high sensitivity to strigolactones exhibited by parasitic plants.	GR24 strigolactone	44-57	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	90-95
34961192-5	2021	Arabidopsis mutant studies indicated that the somatic embryo number was inhibited in max3 and max4 mutants, and this effect was reversed by applications of GR24, a synthetic strigolactone, and exacerbated by TIS108, a SL biosynthetic inhibitor.	GR24 strigolactone	174-187	carotenoid cleavage dioxygenase 7	Arabidopsis thaliana	85-89
34961192-5	2021	Arabidopsis mutant studies indicated that the somatic embryo number was inhibited in max3 and max4 mutants, and this effect was reversed by applications of GR24, a synthetic strigolactone, and exacerbated by TIS108, a SL biosynthetic inhibitor.	GR24 strigolactone	174-187	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	94-98
35489066-0	2022	Transcriptome Analysis Points to BES1 as a Transducer of Strigolactone Effects on Drought Memory in Arabidopsis thaliana.	GR24 strigolactone	57-70	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	33-37
35406919-6	2022	Significantly, MsD14 could physically interact with AtMAX2 and MsMAX2 in the presence of strigolactone, suggesting a similarity between MsD14 and AtD14.	GR24 strigolactone	89-102	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	146-151
35355884-1	2022	DWARF14 (D14) is an alpha/beta-hydrolase and receptor for the plant hormone strigolactone (SL) in angiosperms.	GR24 strigolactone	76-89	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	9-12
35355884-5	2022	A ratiometric fluorescent reporter system was used to monitor degradation of SMXL7 from Arabidopsis thaliana (AtSMXL7) after transient expression in N. benthamiana and treatment with the strigolactone analog GR24.	GR24 strigolactone	187-200	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	77-82
35355884-5	2022	A ratiometric fluorescent reporter system was used to monitor degradation of SMXL7 from Arabidopsis thaliana (AtSMXL7) after transient expression in N. benthamiana and treatment with the strigolactone analog GR24.	GR24 strigolactone	187-200	Double Clp-N motif-containing P-loop nucleoside triphosphate hydrolases superfamily protein	Arabidopsis thaliana	110-117
34791413-1	2022	The synthetic strigolactone (SL) analog, rac-GR24, has been instrumental in studying the role of SLs as well as karrikins because it activates the receptors DWARF14 (D14) and KARRIKIN INSENSITIVE 2 (KAI2) of their signaling pathways, respectively.	GR24 strigolactone	14-27	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	157-164
35362177-3	2022	By characterising max2-1 and max4-1, we found that variation in strigolactone biosynthesis modified multiple metabolic pathways in root tissue, including that of xyloglucan, triterpenoids, fatty acids and flavonoids.	GR24 strigolactone	64-77	carotenoid cleavage dioxygenase 8	Arabidopsis thaliana	29-33
35362177-6	2022	Finally, flavonoid accumulation decreased in max2-1 roots, supporting a role for MAX2 in regulating both strigolactone and flavonoid biosynthesis.	GR24 strigolactone	105-118	RNI-like superfamily protein	Arabidopsis thaliana	45-49
35362177-6	2022	Finally, flavonoid accumulation decreased in max2-1 roots, supporting a role for MAX2 in regulating both strigolactone and flavonoid biosynthesis.	GR24 strigolactone	105-118	RNI-like superfamily protein	Arabidopsis thaliana	81-85
34791413-1	2022	The synthetic strigolactone (SL) analog, rac-GR24, has been instrumental in studying the role of SLs as well as karrikins because it activates the receptors DWARF14 (D14) and KARRIKIN INSENSITIVE 2 (KAI2) of their signaling pathways, respectively.	GR24 strigolactone	14-27	alpha/beta-Hydrolases superfamily protein	Arabidopsis thaliana	175-197
34687296-0	2022	Strigolactone signaling regulates cambial activity through repression of WOX4 by transcription factor BES1.	GR24 strigolactone	0-13	WUSCHEL related homeobox 4	Arabidopsis thaliana	73-77
34687296-0	2022	Strigolactone signaling regulates cambial activity through repression of WOX4 by transcription factor BES1.	GR24 strigolactone	0-13	Brassinosteroid signaling positive regulator (BZR1) family protein	Arabidopsis thaliana	102-106