PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 3500954-2 1987 The stability of copolymers of phosphorylated and dephosphorylated myosin was, however, unknown. copolymers 17-27 myosin heavy chain 14 Homo sapiens 67-73 2479428-7 1989 Vitronectin adsorbed on carboxylic acid-containing copolymers reacted more strongly with a conformationally sensitive antivitronectin monoclonal antibody (MoAb) than vitronectin adsorbed to polystyrene and was more susceptible to cleavage by plasma proteases(s). copolymers 51-61 vitronectin Homo sapiens 0-11 2479428-7 1989 Vitronectin adsorbed on carboxylic acid-containing copolymers reacted more strongly with a conformationally sensitive antivitronectin monoclonal antibody (MoAb) than vitronectin adsorbed to polystyrene and was more susceptible to cleavage by plasma proteases(s). copolymers 51-61 vitronectin Homo sapiens 122-133 2973785-1 1988 The DNA sequence dependence of the ATPase activity of RecA protein has been investigated for a variety of single strand octamer and hexadecamer homopolymers and alternating copolymers. copolymers 173-183 RAD51 recombinase Homo sapiens 54-58 2493000-6 1989 As judged by immunofluorescence localization and by the alteration in the solubility of the endogenous vimentin filaments, filaments containing NF-L appeared to be copolymers with vimentin. copolymers 164-174 neurofilament light chain Homo sapiens 144-148 9944592-0 1988 (AmBn)x copolymers: A computational study of electronic and excitonic properties of quasi-one-dimensional superlattices. copolymers 8-18 ameloblastin Homo sapiens 1-5 3500954-4 1987 Copolymers were typically formed by dialyzing monomeric mixtures into filament-forming buffer but, unexpectedly, could also be formed within minutes of mixing preformed rod and myosin minifilaments. copolymers 0-10 myosin heavy chain 14 Homo sapiens 177-183 18555385-1 1986 Bovine trypsin was crosslinked to human serum albumin (HSA) with glutaraldehyde to form soluble and insoluble copolymers. copolymers 110-120 albumin Bos taurus 40-53 3680315-1 1987 A series of PEO/PLA copolymers, covering a wide range of compositions and segmental lengths, was synthesized, and their morphology was investigated by means of DSC and IR studies. copolymers 20-30 twinkle mtDNA helicase Homo sapiens 12-15 3685024-3 1987 This observation provides a possible explanation for the behavior of copolymers of dephosphorylated and phosphorylated myosin in the presence of nucleotide. copolymers 69-79 myosin heavy chain 14 Homo sapiens 119-125 289438-2 1979 Double-stranded RNA"s, such as the copolymers of polyinosinic and polycytidylic acids and polyadenylic and polyuridylic acids, could not alone induce differentiation of the cells, but enhanced induction of differentiation by low concentrations of the D-factor and induced a significant amount of interferon. copolymers 35-45 leukemia inhibitory factor Mus musculus 251-259 2983990-1 1985 Synthetic copolymers containing tyrosine residues were used to characterize the substrate specificity of the insulin receptor kinase and compare it to tyrosine kinases stimulated by epidermal growth factor, insulin-like growth factor-1 and phorbol ester. copolymers 10-20 insulin Homo sapiens 109-116 7224587-1 1980 Delayed-type hypersensitivity (DTH) to the random copolymers poly(Glu50Tyr50) (GT) or poly(Glu60Ala30Tyr10) (GAT) could be produced in BALB/c mice when the polymers were injected complexed to a methylated bovine serum albumin (mBSA). copolymers 50-60 albumin Mus musculus 212-225 9937879-0 1986 Spin diffusion in block copolymers as studied by pulsed NMR. copolymers 24-34 spindlin 1 Homo sapiens 0-4 33942499-0 2021 Self-Assembly or Coassembly of Multiresponsive Histidine-Containing Elastin-Like Polypeptide Block Copolymers. copolymers 99-109 elastin Homo sapiens 68-75 1101226-2 1975 GTP is found to be misincorporated into both copolymers at a frequency of 1 per 1000-2000 nucleotides polymerized. copolymers 45-55 Dopamine transporter Drosophila melanogaster 30-32 14069522-0 1963 INHIBITION OF LYSOZYME BY SOME COPOLYMERS OF AMINO ACIDS. copolymers 31-41 lysozyme Homo sapiens 14-22 34038105-1 2021 Elastin-like polypeptides (ELPs) are stimulus-responsive protein-based biopolymers, and some ELP block copolymers can assemble into spherical nanoparticles with thermosensitivity. copolymers 103-113 nuclear receptor subfamily 5 group A member 1 Homo sapiens 27-30 33675833-4 2021 The copolymers exhibit self-organization capability in water, with critical association concentration of 42 and 50 mug mL-1. copolymers 4-14 L1 cell adhesion molecule Mus musculus 119-123 1194855-9 1975 Furthermore, immune suppression by the two related copolymers, GT and GAT, are distinct in different strains of mice. copolymers 51-61 glycine-N-acyltransferase Mus musculus 70-73 34057364-2 2021 A series of pH-responsive random copolymers (DPL-DP60) comprising of a pH-responsive moiety 2-((leucinyl)oxy)ethyl methacrylate (l-Leu-HEMA) and hydrophobic methyl methacrylate (MMA) are synthesized and characterized. copolymers 33-43 prion like protein doppel Homo sapiens 45-48 34015226-2 2021 Acrylamide grafting and carboxymethylation of A. chundra gum were carried out and synthesized copolymers were characterized. copolymers 94-104 OTU deubiquitinase with linear linkage specificity Homo sapiens 57-60 33755416-3 2021 Herein, we report a series of copolymers made by melt blending novolac cyanate ester and tetramethylbiphenyl epoxy (NCE/EP) that have demonstrated much superior high-temperature stability over current epoxies. copolymers 30-40 epiregulin Homo sapiens 120-122 33755416-7 2021 The outstanding high-temperature stability, preferred and adjustable processability, and the dielectric properties of the reported NCE/EP copolymers will greatly stimulate further research to formulating robust epoxy molding compounds (EMCs) or underfill for packaging next-generation high-power electronics. copolymers 138-148 epiregulin Homo sapiens 135-137 33444001-5 2021 Moreover, the 1-Y/[Ph3C][B(C6F5)4] catalytic system also could promote the polymerization of butadiene and its copolymerization with isoprene to produce copolymers with high cis-1,4-selectivity and narrow polydispersity. copolymers 153-163 suppressor of cytokine signaling 1 Homo sapiens 174-179 33480461-3 2021 Acrylic acid (AAc), N-vinylpyrrolidone (NVP), and acrylamide (AAm) are copolymerized in water, yielding copolymers with UCST behavior. copolymers 104-114 glycine-N-acyltransferase Homo sapiens 14-17 33606493-0 2021 Bending Behavior and Directed Self-Assembly of Rod-Coil Block Copolymers. copolymers 62-72 kinetochore associated 1 Homo sapiens 47-50 33359482-5 2021 The two block copolymers described in the study were successfully formulated to form hydrogels which delayed the release of lysozyme (> 20 days) in vitro. copolymers 14-24 lysozyme Homo sapiens 124-132 33285462-5 2021 EXPERIMENTS: In this study, a series of spin labeled amphiphilic random copolymers poly(methyl methacrylate-co-acrylic acid) have been synthesized and characterized by FT-IR, UV-Vis spectroscopies, TGA, DSC and water contact angle (CA) techniques. copolymers 72-82 T-box transcription factor 1 Homo sapiens 198-201 33568710-4 2021 The results show that, at a fixed PPG/PEG ratio, block copolymers have larger two-phase region compared with random copolymer. copolymers 55-65 serglycin Homo sapiens 34-37 33556240-9 2021 The 350 and 20 kDa copolymers actively target FRalpha to initialize internationalization. copolymers 19-29 FOS like 1, AP-1 transcription factor subunit Homo sapiens 46-53 33556240-10 2021 However, only the large size and sheet-shaped 350 kDa copolymers disrupt FRalpha signaling. copolymers 54-64 FOS like 1, AP-1 transcription factor subunit Homo sapiens 73-80 33661006-2 2021 However, our knowledge about the mechanism of such a transition is still limited, especially for rod-coil block copolymers. copolymers 112-122 kinetochore associated 1 Homo sapiens 97-100 33661006-9 2021 The gained information can guide the construction of nanoassemblies based on the rod-coil block copolymers. copolymers 96-106 kinetochore associated 1 Homo sapiens 81-84 33423476-0 2021 Stretchable OFET Memories: Tuning the Morphology and the Charge-Trapping Ability of Conjugated Block Copolymers through Soft Segment Branching. copolymers 101-111 POC1 centriolar protein A Homo sapiens 120-124 33572853-3 2021 The usage of the amphiphilic branched silica derivatives associated with oligomeric medium (ASiP) leads to the structuring of block copolymers via the transetherification reaction of the terminal silanol groups of MBC with ASiP. copolymers 132-142 agouti signaling protein Homo sapiens 92-96 33572853-3 2021 The usage of the amphiphilic branched silica derivatives associated with oligomeric medium (ASiP) leads to the structuring of block copolymers via the transetherification reaction of the terminal silanol groups of MBC with ASiP. copolymers 132-142 agouti signaling protein Homo sapiens 223-227 33325677-0 2020 Highly Aligned Carbon Nanowire Array by E-Field Directed Assembly of PAN-Containing Block Copolymers. copolymers 90-100 adenosine deaminase 2 Homo sapiens 69-72 33356301-0 2021 Insight into the Microcosm of the Human Growth Hormone and Its Interactions with Polymers and Copolymers: A Molecular Dynamics Perspective. copolymers 94-104 growth hormone 1 Homo sapiens 40-54 33182803-1 2020 New thermoresponsive graft copolymers with an aromatic polyester backbone and poly(2-isopropyl-2-oxazoline) (PiPrOx) side chains are synthesized and characterized by NMR and GPC. copolymers 27-37 glycophorin C (Gerbich blood group) Homo sapiens 174-177 33334374-0 2020 Alpha-beta transition induced by C18-conjugation of polyalanine and its implication in aqueous solution behavior of poly(ethylene glycol)-polyalanine block copolymers. copolymers 156-166 Bardet-Biedl syndrome 9 Homo sapiens 33-36 33334374-1 2020 BACKGROUND: The aqueous solution behavior of thermosensitive PEG-PA block copolymers as well as secondary structure of PA is expected to significantly change through modification of the hydrophobic PA by long chain alkyl (C18) groups with different configurations. copolymers 74-84 Bardet-Biedl syndrome 9 Homo sapiens 222-225 33303818-0 2020 Surface functionalisation of poly-APO-b-polyol ester cross-linked copolymers as core-shell nanoparticles for targeted breast cancer therapy. copolymers 66-76 apolipoprotein B Homo sapiens 34-39 33266207-3 2020 The introduction of PCL as a second side chain type in addition to PEG resulted in heterografted copolymers with modified properties such as biodegradability. copolymers 97-107 progestagen associated endometrial protein Homo sapiens 67-70 33156603-6 2020 Adequate surface functionalization using asymmetric double-hydrophilic block copolymers, constituted of a metal-binding block and a neutral water-soluble block, provides stabilized YAG:Nd3+ nanocrystals with long-term colloidal stability in aqueous suspensions. copolymers 77-87 mitochondrially encoded NADH dehydrogenase 3 Homo sapiens 185-188 33379370-2 2020 Copolymers were synthesized via the ring-opening polymerization (ROP) process of cyclic monomers, epsilon-caprolactone (CL) or rac-lactide (rac-LA), in the presence of zirconium(IV) octoate (Zr(Oct)4) and poly(ethylene glycol) 200 (PEG 200) as catalyst and initiator, respectively. copolymers 0-10 POU class 5 homeobox 1 Homo sapiens 190-199 32884159-2 2020 Copolymers of two different dithiolane-containing cyclic carbonate monomers and epsilon-caprolactone (CL) were synthesized by ring-opening polymerization using a methoxy-poly(ethylene glycol) (mPEG) initiator and different catalysts (diphenyl phosphate (DPP), methanesulfonic acid (MSA), 1,5,7-triazabicyclo[4.4.0]dec-5-ene (TBD), or Sn(Oct)2). copolymers 0-10 POU class 2 homeobox 2 Homo sapiens 334-342 32872675-1 2020 Green nanocomposites from rosin-limonene (Ros-Lim) copolymers based on Algerian organophilic-clay named Maghnite-CTA+ (Mag-CTA+) were prepared by in-situ polymerization using different amounts (1, 5 and 10% by weight) of Mag-CTA+ and azobisisobutyronitrile as a catalyst. copolymers 51-61 PDZ and LIM domain 5 Homo sapiens 46-49 32842745-0 2020 Formation of Multi-continuous 3D Network Nanostructures with Increased Complexity in ABC-Type Block Copolymers. copolymers 100-110 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 85-88 32786529-6 2020 The covalent modification of oxime-containing copolymers prolonged the activity of BChE in the presence of the VX- and cyclosarin-fluorogenic analogues EMP-MeCyC and CMP-MeCyC, respectively. copolymers 46-56 butyrylcholinesterase Homo sapiens 83-87 32393953-2 2020 Polylactic acid-b-polystyrene diblock bottlebrush copolymers were dispersed in toluene with a concentration of 175 mg ml-1, where they self-assembled into a lamellar phase. copolymers 50-60 interleukin 17F Homo sapiens 118-122 32640158-3 2020 Dynamic light scattering, transmission electron microscopy images, and two dimensional NMR spectra indicated that the PEG-L-PA block copolymers formed inclusion complexes with alpha-CD derivatives. copolymers 133-143 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 176-184 32383883-4 2020 Here, we present how lipid, polymer and hybrid membranes based on mixtures of lipids and copolymers on solid support provide more favourable environment to drive selective and functional attachment of a model redox protein, cytochrome c (cyt c). copolymers 89-99 cytochrome c, somatic Homo sapiens 224-236 32383883-4 2020 Here, we present how lipid, polymer and hybrid membranes based on mixtures of lipids and copolymers on solid support provide more favourable environment to drive selective and functional attachment of a model redox protein, cytochrome c (cyt c). copolymers 89-99 cytochrome c, somatic Homo sapiens 238-243 32309828-5 2020 In the proximity of the star core, geometric constraints promote unfavorable PEO:PS contacts that lead to a behavior similar to dynamically asymmetric miscible polymer blends or disordered copolymers. copolymers 189-199 twinkle mtDNA helicase Homo sapiens 77-80 32307121-5 2020 The molecular weights of the copolymers were evaluated by GPC. copolymers 29-39 glycophorin C (Gerbich blood group) Homo sapiens 58-61 32486492-0 2020 Liquid Crystal Ordering in the Hexagonal Phase of Rod-Coil Diblock Copolymers. copolymers 67-77 kinetochore associated 1 Homo sapiens 50-53 32322851-0 2020 Insulin-induced conformational transition of fluorescent copolymers: a perspective of self-assembly between protein and micellar solutions of smart copolymers. copolymers 57-67 insulin Homo sapiens 0-7 32322851-0 2020 Insulin-induced conformational transition of fluorescent copolymers: a perspective of self-assembly between protein and micellar solutions of smart copolymers. copolymers 148-158 insulin Homo sapiens 0-7 32353997-2 2020 In this study, we report a modification in the conventional fabrication process of (isoporous) flat sheet membranes in which the self-assembly of block copolymers is achieved by providing controlled evaporation conditions using gas flow and the process is introduced as gSNIPS. copolymers 152-162 gastrin Homo sapiens 228-231 32387357-2 2020 In present study association between hen egg white lysozyme and Pluronic triblock-copolymers (L121, P123 and F127) in the bulk of the solution as well as at the aqueous-air and liquid-liquid interfaces was analyzed by means of spectroscopic and radiochemical assay. copolymers 82-92 lysozyme Homo sapiens 51-59 32249484-1 2020 A series of copolymers are prepared via cationic ring-opening polymerization with 1,3-dioxolane (DOL) and trioxymethylene (TOM) as monomers. copolymers 12-22 pre-mRNA processing factor 6 Homo sapiens 123-126 32249484-2 2020 The crystallization behaviors of the copolymers can be suppressed by adjusting the ratio of DOL/TOM. copolymers 37-47 pre-mRNA processing factor 6 Homo sapiens 92-99 32267036-0 2020 Organocatalyzed Living Radical Polymerization of Itaconates and Self-Assemblies of Rod-Coil Block Copolymers. copolymers 98-108 kinetochore associated 1 Homo sapiens 83-86 32267036-2 2020 The block polymerization with functional methacrylates, an acrylate, and styrene yields various rod-coil block copolymers. copolymers 111-121 kinetochore associated 1 Homo sapiens 96-99 31513229-1 2019 Two block copolymers containing two amino-acid derivatives, PEO-b-PLAA and PEO-b-PAAC, were fabricated through atom transfer radical polymerization (ATRP) or reversible addition-fragmentation chain transfer polymerization (RAFT). copolymers 10-20 phospholipase A2 activating protein Homo sapiens 66-70 32125826-12 2020 Rhodamine B had a negative chi for all copolymers with <30 mol % CPTEG tested, indicating a tendency toward miscibility. copolymers 39-49 ras homolog family member B Homo sapiens 0-11 32228907-1 2020 This study investigates stabilization of graphene oxide (GO) nanosheets in polyethylene oxide-polypropylene oxide (PEO-PPO) block copolymers (P103, P123 and F127). copolymers 130-140 protoporphyrinogen oxidase Homo sapiens 119-122 31977118-3 2020 Subsequently, 21-arm star-like coil polymers PtBA-SCOCH3 react with rod-like vinyl-functionalized P3HT to yield functional star-like rod-coil diblock copolymers PtBA-b-P3HT via thiol-ene click reaction, followed by selective hydrolysis of inner PtBA block into PAA block. copolymers 150-160 steroidogenic acute regulatory protein Homo sapiens 21-25 31977118-3 2020 Subsequently, 21-arm star-like coil polymers PtBA-SCOCH3 react with rod-like vinyl-functionalized P3HT to yield functional star-like rod-coil diblock copolymers PtBA-b-P3HT via thiol-ene click reaction, followed by selective hydrolysis of inner PtBA block into PAA block. copolymers 150-160 steroidogenic acute regulatory protein Homo sapiens 123-127 33463223-6 2020 In this work, we hypothesized that new copolymers composed of CPTEG and SA would combine the advantages of both monomers in terms of enhanced thermal properties, maintaining antigenicity of encapsulated proteins following nanoparticle synthesis, and superior cellular internalization and activation by APCs, demonstrated by the upregulation of costimulatory markers CD80, CD86, and CD40, as well as the secretion of proinflammatory cytokines IL-6, IL-1beta, and TNF-alpha. copolymers 39-49 CD80 molecule Homo sapiens 366-370 33463223-6 2020 In this work, we hypothesized that new copolymers composed of CPTEG and SA would combine the advantages of both monomers in terms of enhanced thermal properties, maintaining antigenicity of encapsulated proteins following nanoparticle synthesis, and superior cellular internalization and activation by APCs, demonstrated by the upregulation of costimulatory markers CD80, CD86, and CD40, as well as the secretion of proinflammatory cytokines IL-6, IL-1beta, and TNF-alpha. copolymers 39-49 CD86 molecule Homo sapiens 372-376 33463223-6 2020 In this work, we hypothesized that new copolymers composed of CPTEG and SA would combine the advantages of both monomers in terms of enhanced thermal properties, maintaining antigenicity of encapsulated proteins following nanoparticle synthesis, and superior cellular internalization and activation by APCs, demonstrated by the upregulation of costimulatory markers CD80, CD86, and CD40, as well as the secretion of proinflammatory cytokines IL-6, IL-1beta, and TNF-alpha. copolymers 39-49 CD40 molecule Homo sapiens 382-386 33463223-6 2020 In this work, we hypothesized that new copolymers composed of CPTEG and SA would combine the advantages of both monomers in terms of enhanced thermal properties, maintaining antigenicity of encapsulated proteins following nanoparticle synthesis, and superior cellular internalization and activation by APCs, demonstrated by the upregulation of costimulatory markers CD80, CD86, and CD40, as well as the secretion of proinflammatory cytokines IL-6, IL-1beta, and TNF-alpha. copolymers 39-49 interleukin 6 Homo sapiens 442-446 33463223-6 2020 In this work, we hypothesized that new copolymers composed of CPTEG and SA would combine the advantages of both monomers in terms of enhanced thermal properties, maintaining antigenicity of encapsulated proteins following nanoparticle synthesis, and superior cellular internalization and activation by APCs, demonstrated by the upregulation of costimulatory markers CD80, CD86, and CD40, as well as the secretion of proinflammatory cytokines IL-6, IL-1beta, and TNF-alpha. copolymers 39-49 interleukin 1 alpha Homo sapiens 448-456 33463223-6 2020 In this work, we hypothesized that new copolymers composed of CPTEG and SA would combine the advantages of both monomers in terms of enhanced thermal properties, maintaining antigenicity of encapsulated proteins following nanoparticle synthesis, and superior cellular internalization and activation by APCs, demonstrated by the upregulation of costimulatory markers CD80, CD86, and CD40, as well as the secretion of proinflammatory cytokines IL-6, IL-1beta, and TNF-alpha. copolymers 39-49 tumor necrosis factor Homo sapiens 462-471 31475270-0 2019 Synthesis of Ag2O decorated hierarchical TiO2 templated by double comb copolymers for efficient solar water splitting. copolymers 71-81 anterior gradient 2, protein disulphide isomerase family member Homo sapiens 13-16 31268691-7 2019 The copolymers crystallize as an orthorhombic lattice that is typical for PCL, and they formed more elastic, softer, and less hydrophobic films with faster degradation rates than PCL. copolymers 4-14 PHD finger protein 1 Homo sapiens 74-77 31066491-1 2019 In this study, a new strategy to synthesize random and alternating multiblock copolymers (MBCs) by the polycondensation of macromonomers" terminal hydroxyl groups with [CpRu(CH3 CN)3 ]PF6 /quinaldic acid as the catalyst is reported, which is often used for the preparation of a variety of biological small molecules via the reaction of allyl ethers. copolymers 78-88 sperm associated antigen 17 Homo sapiens 184-187 31268691-7 2019 The copolymers crystallize as an orthorhombic lattice that is typical for PCL, and they formed more elastic, softer, and less hydrophobic films with faster degradation rates than PCL. copolymers 4-14 PHD finger protein 1 Homo sapiens 179-182 31070896-4 2019 More importantly, Dex- g-K nF m copolymers did not induce drug resistance of MRSA up to 17 passages. copolymers 32-42 neurofilament, medium polypeptide Mus musculus 27-31 31079690-0 2019 Synthesis of graft copolymers of chitosan-poly(caprolactone) by lipase catalysed reactive extrusion. copolymers 19-29 PAN0_003d1715 Moesziomyces antarcticus 64-70 31312502-5 2019 It also exhibits excellent control over the stereo-structure of the butadiene segments in the prepared copolymers, and the SBS polymers with high cis-1,4 unit content were easily achieved. copolymers 103-113 suppressor of cytokine signaling 1 Homo sapiens 146-151 31117745-0 2019 Influence of Cholesterol and Bilayer Curvature on the Interaction of PPO-PEO Block Copolymers with Liposomes. copolymers 83-93 protoporphyrinogen oxidase Homo sapiens 69-72 30889482-5 2019 When mRNA encoding a cartilage-anabolic transcription factor, runt-related transcription factor-1, was administered to a rat model of coccygeal disk degeneration using a polyplex nanomicelle composed of polyethylene glycol-polyamino acid block copolymers and mRNA, the disk height was maintained to a significantly higher extent ( 81%) compared to saline control (69%), with prevention of fibrosis in the disk tissue. copolymers 244-254 RUNX family transcription factor 1 Rattus norvegicus 62-97 31002839-3 2019 We describe a novel 3D printing technique based on two complementary liquid copolymers, PEG4-PCL-SC and PEG4-PCL-NH2, that are injected in a coordinated fashion and react with each other to form a pre-designed 3D pill. copolymers 76-86 PHD finger protein 1 Homo sapiens 93-96 31117745-1 2019 Interactions of nonionic poly(ethylene oxide)- b-poly(propylene oxide) (PEO-PPO) block copolymers, known as Pluronics or poloxamers, with cell membranes have been widely studied for a host of biomedical applications. copolymers 87-97 protoporphyrinogen oxidase Homo sapiens 76-79 31172045-1 2019 Silk-elastin block copolymers have such physical and biological properties that make them attractive biomaterials for applications ranging from tissue regeneration to drug delivery. copolymers 19-29 elastin Homo sapiens 5-12 31172045-2 2019 Silk-elastin block copolymers that only assemble into fibrils at high concentrations can be used for a template-induced fibril assembly. copolymers 19-29 elastin Homo sapiens 5-12 31075823-2 2019 The chemical structure and macromolecular weight of obtained copolymers were characterized by 1H NMR, 13C NMR, and GPC. copolymers 61-71 glycophorin C (Gerbich blood group) Homo sapiens 115-118 30789709-1 2019 The self-assembly of nanostructures from elastin-like (poly)peptide (ELP) containing block copolymers has been a subject of intense investigation over decades. copolymers 91-101 nuclear receptor subfamily 5 group A member 1 Homo sapiens 41-67 30789709-1 2019 The self-assembly of nanostructures from elastin-like (poly)peptide (ELP) containing block copolymers has been a subject of intense investigation over decades. copolymers 91-101 nuclear receptor subfamily 5 group A member 1 Homo sapiens 69-72 30771551-4 2019 These copolymers self-assemble into micellar nanoparticles, and are highly effective against various cancer cell lines including human breast cancer (BCap37), liver cancer (HepG2), lung cancer (A549) and epidermoid carcinoma (A431) cell lines as well as MDR Bats-72 and Bads-200 cancer cells that were developed from BCap37. copolymers 6-16 prohibitin 2 Homo sapiens 150-156 30771551-4 2019 These copolymers self-assemble into micellar nanoparticles, and are highly effective against various cancer cell lines including human breast cancer (BCap37), liver cancer (HepG2), lung cancer (A549) and epidermoid carcinoma (A431) cell lines as well as MDR Bats-72 and Bads-200 cancer cells that were developed from BCap37. copolymers 6-16 prohibitin 2 Homo sapiens 317-323 30829473-6 2019 To solve this challenge, we designed new amphiphilic block copolymers with high content of sp2-hybridized carbon in the hydrophobic segments that were relatively stable and could be in situ converted into residual carbon to support the mesoporous structure, via living free radical polymerization. copolymers 59-69 Sp2 transcription factor Homo sapiens 91-94 30694604-5 2019 Cationic PHB copolymers show effectiveness as antimicrobial agents, with minimum inhibitory concentration values 0.24-0.65 microm (or micromol dm-3 ) (or 32-128 microg mL-1 ) against Gram-positive and Gram-negative bacteria. copolymers 13-23 L1 cell adhesion molecule Mus musculus 168-172 30829473-8 2019 In this Account, we first outline the features of sp2-hybridized carbon-containing block copolymers synthesized via living free radical polymerization, particularly their pyrolysis behavior in converting into residual carbon. copolymers 89-99 Sp2 transcription factor Homo sapiens 50-53 30829473-13 2019 These newly developed soft-templating synthesis methods that rely on sp2-hybridized carbon-containing block copolymers will open a new avenue for the design and application of ordered mesoporous semiconducting metal oxides in various fields. copolymers 108-118 Sp2 transcription factor Homo sapiens 69-72 30699400-0 2019 MSC differentiation on two-photon polymerized, stiffness and BMP2 modified biological copolymers. copolymers 86-96 bone morphogenetic protein 2 Homo sapiens 61-65 30589535-2 2019 Copolymers based on N-acryloxysuccinimide (NAS) and a low fouling monomer (either N, N-dimethylacrylamide (DMA), N-(2-hydroxypropyl)acrylamide (HPA), or N-acryloylmorpholine (NAM)) were grafted from the fiber surface to impart surface functionality and to reduce nonspecific protein adsorption. copolymers 0-10 SH3 and cysteine rich domain 3 Homo sapiens 153-180 30608144-4 2019 Experimentally determined cloud points for different copolymers in aqueous solutions indicate shift of lower critical solution temperature (LCST) to lower values with the increase of GMA content in copolymers and increase of the lactam ring size. copolymers 53-63 myelin associated glycoprotein Homo sapiens 183-186 30318666-5 2018 Copolymers with T g s of -11 C or T m s from 5 to 15 C and thermal decomposition >200 C depending on the comonomer ratio, are obtained as determined by differential scanning calorimetry/TGA. copolymers 0-10 T-box transcription factor 1 Homo sapiens 192-195 30608144-4 2019 Experimentally determined cloud points for different copolymers in aqueous solutions indicate shift of lower critical solution temperature (LCST) to lower values with the increase of GMA content in copolymers and increase of the lactam ring size. copolymers 198-208 myelin associated glycoprotein Homo sapiens 183-186 30580525-5 2019 Quartz crystal microbalance with dissipation monitoring (QCM-D) measurements show that formation of SHB on SiO2 by vesicle fusion depends on the mass fractions of lipids and block copolymers. copolymers 180-190 SH2 domain containing adaptor protein B Homo sapiens 100-103 30441905-5 2018 Force spectroscopy experiments also reveal a more stretched conformation of the PEO chains for the block copolymers with a shorter PLLA block. copolymers 105-115 twinkle mtDNA helicase Homo sapiens 80-83 30550258-3 2019 To shine more light on the relationship between nanoparticle structure and cell uptake, we have designed several micelles based on fructose containing block copolymers, which are selective to GLUT5 receptors found on breast cancer cell lines. copolymers 157-167 solute carrier family 2 member 5 Homo sapiens 192-197 30516954-2 2019 Herein, we present three copolymers (PT1, PT2, PT3) made through tuning pi-bridges (without any group, thiophene, and 3-hexylthieno[3,2- b]thiophene) between electron-rich (D: BDTT) and -deficient (A: BDD) units. copolymers 25-35 zinc finger protein 77 Homo sapiens 37-40 30516954-2 2019 Herein, we present three copolymers (PT1, PT2, PT3) made through tuning pi-bridges (without any group, thiophene, and 3-hexylthieno[3,2- b]thiophene) between electron-rich (D: BDTT) and -deficient (A: BDD) units. copolymers 25-35 zinc finger protein 135 Homo sapiens 47-50 30317092-4 2019 The results indicated that branched copolymers with high molecular weight like AL-g-DMC1 and AL-g-DMC2 exerted excellent color removals and satisfactory floc properties in comparison with linear polymers with low molecular weight (AL-GTA1 and AL-GTA2). copolymers 36-46 DNA meiotic recombinase 1 Homo sapiens 84-88 30360629-4 2018 The authors report here the surface characterization of three different HEMA hydrogel copolymers and their effects on the orientation and conformation of surface-bound KGF. copolymers 86-96 fibroblast growth factor 7 Homo sapiens 168-171 30296017-4 2018 Cationic block copolymers are designed to complex miR-29a, and subsequently mixed with the poly(ethylene glycol) (PEG) gelation precursors and MMP-cleavable peptide cross-linkers for in situ formation of polyplex micelle-encapsulated hydrogels in the diseased IVDs. copolymers 15-25 microRNA 29a Homo sapiens 50-57 30360629-10 2018 KGF at the surface of these copolymers can be differentiated by Fourier-transform infrared-attenuated total reflectance spectroscopy and time-of-flight secondary ion mass spectrometry in conjunction with principal component analysis. copolymers 28-38 fibroblast growth factor 7 Homo sapiens 0-3 30360629-11 2018 The differences in KGF orientation and conformation between these copolymers may result in different biological responses in future cell-based experiments. copolymers 66-76 fibroblast growth factor 7 Homo sapiens 19-22 30191400-10 2018 CMDR values of 13 block copolymers have been determined. copolymers 24-34 gap junction protein alpha 1 Homo sapiens 0-4 30216076-2 2018 For comparison, behaviors of the surface restructuring and fibrinogen adsorption on the random copolymers containing similar terminal groups were also investigated. copolymers 95-105 fibrinogen beta chain Homo sapiens 59-69 30429875-6 2018 Results: On-demand designed paclitaxel dimeric prodrug could co-precipitate with amphiphilic copolymers to form ultra-stable uPA-PTXD NPs with high drug loading capacity. copolymers 93-103 proline rich acidic protein 1 Homo sapiens 125-128 30966679-2 2018 The resulting copolymers feature molar masses from 40,000 to 100,000 g/mol according to static light scattering and an SPA content of up to 5.3%. copolymers 14-24 surfactant protein A2 Homo sapiens 119-122 30091815-4 2018 The precursor polymer and final block copolymers are characterized by 1 H NMR, FT-IR, GPC, and DSC analyses. copolymers 38-48 glycophorin C (Gerbich blood group) Homo sapiens 86-89 29969183-4 2018 The results show that ABC triblock copolymers form smaller and more stable polyplexes with plasmid DNA than AB diblock copolymers-as verified by long-term aggregation and ethidium bromide exclusion studies-protect the DNA more effectively against nucleases, and provide better transfection efficiencies, as indicated by total protein as well as luciferase expression. copolymers 35-45 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 22-25 29698604-4 2018 Cellular uptake of PEG-CNA-RHO was detected within 30 s, and the amount internalized increased over the course of 1 h. Moreover, these copolymers were internalized within cells to a higher degree than controls consisting of either rhodamine tagged PEG or the rhodamine alone. copolymers 135-145 protein phosphatase 3, catalytic subunit, alpha isoform Mus musculus 23-26 29698604-7 2018 These results indicate that CNA copolymers are cytocompatible and are readily internalized by cells, supporting the idea that CNAs are a promising alternative to DNA in antisense therapy applications. copolymers 32-42 protein phosphatase 3, catalytic subunit, alpha isoform Mus musculus 28-31 29508561-4 2018 The optimum gel systems obtained from the meta-substituted copolymers (m-PAP) are stable at physiological pH and nontoxic to mammalian dermal cells. copolymers 59-69 regenerating family member 3 alpha Homo sapiens 73-76 33435039-0 2018 Multitargeting Peptide-Functionalized Star-Shaped Copolymers with Comblike Structure and a POSS-Core To Effectively Transfect Endothelial Cells. copolymers 50-60 steroidogenic acute regulatory protein Homo sapiens 38-42 29995057-0 2018 Supramolecular alternate donor-acceptor copolymers mediated by PtPt metal-metal interactions and their photocatalytic applications. copolymers 40-50 protein tyrosine phosphatase non-receptor type 2 Homo sapiens 63-67 30960795-7 2018 Thermal properties of the prepared copolymers were characterized by thermogravimetric analysis and differential scanning calorimetry (TGA-DSC). copolymers 35-45 desmocollin 3 Homo sapiens 138-141 28683649-3 2018 The structure of the copolymers was characterized by HNMR, FTIR, DSC and GPC techniques. copolymers 21-31 glycophorin C (Gerbich blood group) Homo sapiens 73-76 29733637-7 2018 The anticoagulant action of copolymers is probably mediated by antithrombin, but it differs from that of unfractionated heparin. copolymers 28-38 serpin family C member 1 Homo sapiens 63-75 29993109-5 2018 Optimization diagrams indicated the metallocene m-EPR copolymers are efficient impact modifiers for polypropylene and showed good balancing of mechanical properties in iPP/m-EPR blends. copolymers 54-64 intracisternal A particle-promoted polypeptide Homo sapiens 168-171 29747513-0 2018 Cholesterol and Morpholine Grafted Cationic Amphiphilic Copolymers for miRNA-34a Delivery. copolymers 56-66 microRNA 34a Homo sapiens 71-80 29747513-3 2018 Herein we report cationic amphiphilic copolymers grafted with cholesterol (chol), N, N-dimethyldipropylenetriamine (cation chain) and 4-(2-aminoethyl)morpholine (morph) for miR-34a delivery. copolymers 38-48 microRNA 34a Homo sapiens 173-180 32254384-5 2018 After that, the prodrug and the gene vector copolymers were mixed in an aqueous solution in order to self-assemble into hybrid micelles, which could then condense the p53 gene and finally form DOX prodrug/p53 co-loaded nanoparticles. copolymers 44-54 tumor protein p53 Homo sapiens 167-170 29848991-5 2018 At physiological conditions, the pH-sensitive copolymers were anionic and interacted electrostatically with the cationic crosslinker PEG-Lys2, forming the electrostatically-crosslinked polymer-liposomes and stabilizing the liposomal structure. copolymers 46-56 aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase Homo sapiens 137-141 32254384-5 2018 After that, the prodrug and the gene vector copolymers were mixed in an aqueous solution in order to self-assemble into hybrid micelles, which could then condense the p53 gene and finally form DOX prodrug/p53 co-loaded nanoparticles. copolymers 44-54 tumor protein p53 Homo sapiens 205-208 30966610-3 2018 Here, the effect of double hydrophilic block copolymers (DHBCs) on alpha-CD/PEG hydrogel properties is investigated. copolymers 45-55 progestagen associated endometrial protein Homo sapiens 76-79 29587473-3 2018 Considering the excellent cooperative action of zinc acetate and a broad scope of aniline derivatives with different functional groups to control ROP of BLG-NCA, this method may offer a useful platform enabling the rapid generation of end-functionalized PBLG and block copolymers for numerous biomedical applications. copolymers 269-279 CEA cell adhesion molecule 4 Homo sapiens 157-160 29425761-3 2018 To address these, a family of structurally related copolymers comprising polyethylene glycol, mPEG2k, and poly(glutamic acid) with linear A-B (mPEG2k-lin-GA) and miktoarm A-B3 (mPEG2k-mik-(GA)3) macromolecular architectures was investigated as potential protein stabilisers. copolymers 51-61 insulin-like growth factor 2 Mus musculus 94-99 29425761-4 2018 These copolymers form non-covalent nanocomplexes with a model protein (lysozyme) which can be formulated into dry powders by spray-drying using common aerosol excipients (mannitol, trehalose and leucine). copolymers 6-16 lysozyme Homo sapiens 71-79 30966586-2 2018 The obtained copolymers were characterized by FT-IR, 1H NMR, DSC, and TGA. copolymers 13-23 T-box transcription factor 1 Homo sapiens 70-73 30966419-0 2018 Structure-Function Relationships in PMA and PMAT Series Copolymers for Polymer Solar Cells. copolymers 56-66 solute carrier family 29 member 4 Homo sapiens 44-48 30966419-1 2018 Two series (PMA and PMAT) of two-dimensional donor-acceptor copolymers consisting of a 3,4-bis(4-bromophenyl)maleimide derivative and triphenylamine with a conjugated side chain were designed and synthesized to probe their structure-function relationships for use in bulk heterojunction (BHJ) polymer solar cells (PSCs). copolymers 60-70 solute carrier family 29 member 4 Homo sapiens 20-24 30966419-8 2018 PSCs based on PMA- and PMAT-series copolymers had power conversion efficiencies (PCEs) ranging from 2.05-2.16% and 3.14-4.01%, respectively. copolymers 35-45 solute carrier family 29 member 4 Homo sapiens 23-27 29381853-7 2018 Our hierarchical GNR fabrication strategy is based on differences in the dissociation energies of C-Br and C-I bonds that allow control over the growth sequence of the block copolymers from which GNRs are formed and consequently yields a significantly higher proportion of single-junction GNR heterostructures. copolymers 174-184 carbonyl reductase 1 Homo sapiens 98-102 29565307-3 2018 Temperature and recognition dual responsivity of the copolymers was investigated by cloud point (Tcp) and dynamic light scattering (DLS), respectively. copolymers 53-63 serine peptidase inhibitor Kazal type 1 Homo sapiens 97-100 29565307-6 2018 For these copolymers, Tcp decreases with increasing content of AdMA unit in the copolymers. copolymers 10-20 serine peptidase inhibitor Kazal type 1 Homo sapiens 22-25 29565307-6 2018 For these copolymers, Tcp decreases with increasing content of AdMA unit in the copolymers. copolymers 80-90 serine peptidase inhibitor Kazal type 1 Homo sapiens 22-25 30966374-5 2018 The influence of the CH=CH bonds along with the fabrication conditions on the crystallization and ferroelectric relaxation of the resultant copolymers (referred to P(VDF-TrFE-DB)) was carefully characterized and discussed. copolymers 140-150 churchill domain containing 1 Homo sapiens 21-26 29195275-0 2018 Functional Modification of Silica through Enhanced Adsorption of Elastin-Like Polypeptide Block Copolymers. copolymers 96-106 elastin Homo sapiens 65-72 29288085-2 2018 PAG can self-assemble into micelles as amphiphilic block copolymers, which exhibits an excellent loading ability for the co-delivery of docetaxel (DTX) and MMP-9 shRNA with adjustable dosing ratios. copolymers 57-67 phosphoprotein membrane anchor with glycosphingolipid microdomains 1 Homo sapiens 0-3 29288085-2 2018 PAG can self-assemble into micelles as amphiphilic block copolymers, which exhibits an excellent loading ability for the co-delivery of docetaxel (DTX) and MMP-9 shRNA with adjustable dosing ratios. copolymers 57-67 matrix metallopeptidase 9 Homo sapiens 156-161 29195275-2 2018 Here, we use computational and experimental approaches to investigate the adsorption behavior of thermally responsive polypeptide block copolymers (elastin-like polypeptides, ELPs) onto silica surfaces, and to explore the effects of surface affinity and micellization on the adsorption kinetics and the resultant polypeptide layers. copolymers 136-146 elastin Homo sapiens 148-155 29195275-7 2018 These observations provide guidance on the use of ELP block copolymers as building blocks for fabricating smart surfaces and interfaces with programmable architecture and functionality. copolymers 60-70 nuclear receptor subfamily 5 group A member 1 Homo sapiens 50-53 33418746-5 2018 Interestingly, the CSC micelles with hydrophobic PCL middle layer show a greater drug loading capacity as well as a higher fluorescence quantum yield (Phi) relative to the core-shell micelles self-assembled from the control of PF-b-POEGMA diblock copolymers without PCL sequence due to having more hydrophobic spaces and better separation of PF sequence provided simultaneously by the PCL central block. copolymers 247-257 PHD finger protein 1 Homo sapiens 49-52 29264915-2 2018 The present study exploits the inherently featured electrostatic interactions of the ion pairs in polymeric ionic liquids (PILs) as the driving force to fabricate healable PIL copolymers. copolymers 176-186 serpin family A member 2 (gene/pseudogene) Homo sapiens 123-126 29279130-4 2018 Copolymers were characterized by FT-IR and NMR spectroscopies, TGA, DSC and morphological analysis by AFM and SEM microscopy, confirming the grafting of PNIPAAm onto polysaccharide backbone. copolymers 0-10 T-box transcription factor 1 Homo sapiens 63-66 29279130-4 2018 Copolymers were characterized by FT-IR and NMR spectroscopies, TGA, DSC and morphological analysis by AFM and SEM microscopy, confirming the grafting of PNIPAAm onto polysaccharide backbone. copolymers 0-10 desmocollin 3 Homo sapiens 68-71 29456812-4 2018 The resulting purified copolymers were characterized by GPC, NMR, FTIR, XRD and DSC. copolymers 23-33 glycophorin C (Gerbich blood group) Homo sapiens 56-59 29196289-7 2018 The wide substrate range of the BioF tag presumably enables protein immobilization in vitro of virtually all natural PHAs as well as blends, copolymers, or artificial chemically modified derivatives with novel physicochemical properties. copolymers 141-151 8-amino-7-oxononanoate synthase Pseudomonas putida KT2440 32-36 30966142-6 2018 However, parent copolymers with distinct PPO moieties do not affirmatively lead to non-cooperative binding, such as the L92 + P84 system. copolymers 16-26 protoporphyrinogen oxidase Homo sapiens 41-44 29264915-3 2018 The healable PIL copolymers are fabricated through the copolymerization of the IL monomers with ethyl acrylate followed by the replacement of Br- counteranions with bulkier ones such as bis(trifluoromethanesulfonyl)imide (TFSI-). copolymers 17-27 serpin family A member 2 (gene/pseudogene) Homo sapiens 13-16 29264915-4 2018 Without modifying the chemical structures of the PIL moieties, the healing performance of the as-prepared PIL copolymers can be effectively mediated by their counteranions. copolymers 110-120 serpin family A member 2 (gene/pseudogene) Homo sapiens 49-52 29264915-4 2018 Without modifying the chemical structures of the PIL moieties, the healing performance of the as-prepared PIL copolymers can be effectively mediated by their counteranions. copolymers 110-120 serpin family A member 2 (gene/pseudogene) Homo sapiens 106-109 29264915-5 2018 The PIL copolymers that do not possess healability when paired with Br- counteranions become healable after exchanging the Br- counteranions with larger-sized ones (e.g., TFSI-). copolymers 8-18 serpin family A member 2 (gene/pseudogene) Homo sapiens 4-7 29264915-6 2018 The PIL copolymers paired with bulky counteranions exhibit enhanced chain mobility and highly reversible ion-pair interactions, which facilitate the healing process. copolymers 8-18 serpin family A member 2 (gene/pseudogene) Homo sapiens 4-7 29264915-7 2018 The PIL copolymers paired with TFSI- anions can completely heal the damage/cut upon heating at 55 C for 7.5 h. Meanwhile, the counteranions with larger sizes not only benefit the healing performance of the PIL copolymers but also enhance their ion conductivity. copolymers 8-18 serpin family A member 2 (gene/pseudogene) Homo sapiens 4-7 29264915-7 2018 The PIL copolymers paired with TFSI- anions can completely heal the damage/cut upon heating at 55 C for 7.5 h. Meanwhile, the counteranions with larger sizes not only benefit the healing performance of the PIL copolymers but also enhance their ion conductivity. copolymers 8-18 serpin family A member 2 (gene/pseudogene) Homo sapiens 207-210 29264915-7 2018 The PIL copolymers paired with TFSI- anions can completely heal the damage/cut upon heating at 55 C for 7.5 h. Meanwhile, the counteranions with larger sizes not only benefit the healing performance of the PIL copolymers but also enhance their ion conductivity. copolymers 211-221 serpin family A member 2 (gene/pseudogene) Homo sapiens 4-7 29264915-7 2018 The PIL copolymers paired with TFSI- anions can completely heal the damage/cut upon heating at 55 C for 7.5 h. Meanwhile, the counteranions with larger sizes not only benefit the healing performance of the PIL copolymers but also enhance their ion conductivity. copolymers 211-221 serpin family A member 2 (gene/pseudogene) Homo sapiens 207-210 29264915-8 2018 The ion conductivity of the PIL copolymers paired with TFSI- is an order of magnitude higher than that of the PIL copolymers paired with Br-. copolymers 32-42 serpin family A member 2 (gene/pseudogene) Homo sapiens 28-31 29264915-8 2018 The ion conductivity of the PIL copolymers paired with TFSI- is an order of magnitude higher than that of the PIL copolymers paired with Br-. copolymers 114-124 serpin family A member 2 (gene/pseudogene) Homo sapiens 110-113 29264915-9 2018 Therefore, the as-prepared healable PIL copolymers are potentially useful as solid electrolytes in PIL-based energy devices to improve their safety and reliability. copolymers 40-50 serpin family A member 2 (gene/pseudogene) Homo sapiens 36-39 29264915-9 2018 Therefore, the as-prepared healable PIL copolymers are potentially useful as solid electrolytes in PIL-based energy devices to improve their safety and reliability. copolymers 40-50 serpin family A member 2 (gene/pseudogene) Homo sapiens 99-102 29235345-2 2018 Pegylated and Tat-decorated fluorescent nanoparticles (FNPs) were produced by nanoprecipitation, starting from two synthetic copolymers, and showed nanometric sizes (~70 nm), a slightly negative zeta potential, and high cytocompatibility toward human bronchial epithelium cells. copolymers 125-135 tyrosine aminotransferase Homo sapiens 14-17 30966002-3 2017 The linear first-order kinetic plot, the linear evolutions of the molar mass with total monomer conversion, and the relatively low dispersity (D~1.55) of the resulting copolymers suggest that this cobalt complex provides some degree of control over the copolymerization of VAc and MAF-TBE. copolymers 168-178 MAF bZIP transcription factor Homo sapiens 281-284 29068509-1 2018 Two donor-acceptor (D-A) type conjugated copolymers, P1 and P2, are designed and synthesized. copolymers 41-51 crystallin gamma F, pseudogene Homo sapiens 53-62 28695530-2 2017 The structures of the obtained copolymers including variety of end groups were determined at the molecular level with the aid of electrospray ionization multistage mass spectrometry (ESI-MSn). copolymers 31-41 moesin Homo sapiens 187-190 28412223-3 2017 Herein, we engineered a novel delivery platform based on hybrid injectable hydrogels, in which pH- and temperature-responsive biodegradable copolymers were site-specifically coupled to the sulfhydryl group of human serum albumin, which effectively enhances the stability and circulation half-life of the biological drug, recombinant uricase enzyme (Uox). copolymers 140-150 urate oxidase Mus musculus 349-352 28888060-5 2017 When we used a mixture of actin filaments and copolymers of actin and acto-S1dC, a chimeric protein of actin and the myosin motor domain, HMM-GFP preferentially formed clusters along the copolymers. copolymers 46-56 myosin heavy chain 14 Homo sapiens 117-123 29068544-2 2017 In the formation of the nanoparticles, the beta-CD/admantane inclusion complex integrates poly(2-methyl-2-oxazoline) and poly(aspartic acid) chains to form pseudoblock copolymers, followed by the coordination between carboxyl groups in P(Asp) block and cisplatin. copolymers 168-178 beta-carotene oxygenase 1 Mus musculus 43-50 29139616-5 2017 Gene knockdown experiments indicate high siRNA delivery and MYC gene knockdown in MCF-7 breast cancer cells for eight of the nine studied block copolymers. copolymers 144-154 MYC proto-oncogene, bHLH transcription factor Homo sapiens 60-63 28927630-4 2017 The multi-armed structures, chemical compositions and phase separation of these EC brush copolymers were confirmed by FT-IR, 1H NMR, GPC, DSC, TEM and SEM. copolymers 89-99 glycophorin C (Gerbich blood group) Homo sapiens 133-136 28927630-4 2017 The multi-armed structures, chemical compositions and phase separation of these EC brush copolymers were confirmed by FT-IR, 1H NMR, GPC, DSC, TEM and SEM. copolymers 89-99 desmocollin 3 Homo sapiens 138-141 28985085-0 2017 Effect of Architecture on Micelle Formation and Liquid-Crystalline Ordering in Solutions of Block Copolymers Comprising Flexible and Rigid Blocks: Rod-Coil vs Y-Shaped vs Comblike Copolymers. copolymers 98-108 coilin Homo sapiens 151-155 27184583-3 2017 PLA- Pluronic (PLA-P) and PLA-Tetronic (PLA-T) new copolymers were shaped as knitted patches and were associated with collagen I (Coll) and collagen I/chondroitine-sulfate (Coll CS) 3-dimensional matrices. copolymers 53-63 plasminogen activator, tissue type Rattus norvegicus 27-47 28757421-2 2017 Structural aspects of cross-linked graft copolymers have been characterized by FTIR, SEM, TGA/DTA, XRD and swelling behavior at pH 2.2, 7.0 and 9.4. copolymers 41-51 T-box transcription factor 1 Homo sapiens 90-93 30965921-3 2017 The anion-exchange reaction of the poly(NVI-Br) in the block copolymers with lithium bis(trifluoromethanesulfonyl)imide (LiNTf2) proceeded selectively to afford amphiphilic block copolymers composed of hydrophobic poly(NVI-NTf2) and hydrophilic poly(NIPAM). copolymers 61-71 nuclear transport factor 2 Homo sapiens 123-127 30965921-3 2017 The anion-exchange reaction of the poly(NVI-Br) in the block copolymers with lithium bis(trifluoromethanesulfonyl)imide (LiNTf2) proceeded selectively to afford amphiphilic block copolymers composed of hydrophobic poly(NVI-NTf2) and hydrophilic poly(NIPAM). copolymers 179-189 nuclear transport factor 2 Homo sapiens 123-127 28695530-6 2017 The ESI-MSn technique applied in this study has been proven to be a useful tool in structural studies of novel graft copolymers as well as their degradation products. copolymers 117-127 moesin Homo sapiens 8-11 28857572-2 2017 Recently, a very straightforward methodology for fabricating asymmetric polymersome was developed by Lodge"s group through the coassembly of polystyrene-b-poly(ethylene oxide) (PS-b-PEO) and polybutadiene-b-poly(ethylene oxide) (PB-b-PEO) block copolymers at the interface of a polystyrene/polybutadiene/chloroform (PS/PB/CHCl3) emulsion. copolymers 245-255 surfactant protein B Homo sapiens 177-179 28830143-4 2017 The series of copolymers that we designed is composed of two blocks of zwitterionic sulfobetaine (SBMA) monomers and one block of glycidyl methacrylate (GMA). copolymers 14-24 androgen receptor Homo sapiens 98-102 28857572-2 2017 Recently, a very straightforward methodology for fabricating asymmetric polymersome was developed by Lodge"s group through the coassembly of polystyrene-b-poly(ethylene oxide) (PS-b-PEO) and polybutadiene-b-poly(ethylene oxide) (PB-b-PEO) block copolymers at the interface of a polystyrene/polybutadiene/chloroform (PS/PB/CHCl3) emulsion. copolymers 245-255 twinkle mtDNA helicase Homo sapiens 182-185 28606810-3 2017 Two different amphiphilic copolymers, poly(ethylene glycol)3400-aconityl linkage-poly(l-glutamic acid)15-poly(l-histidine)10-poly(l-leucine)10 and LyP1-poly(ethylene glycol)1100-poly(l-glutamic acid)15-poly(l-histidine)10-poly(l-leucine)10, were exploited to self-assemble into micelles in aqueous phase. copolymers 26-36 protein tyrosine phosphatase non-receptor type 22 Homo sapiens 147-151 28578956-2 2017 The synthesized graft copolymers were well characterized by 1H NMR, FTIR, XRD, SEM, TGA/DTA and AFM analyses. copolymers 22-32 T-box transcription factor 1 Homo sapiens 84-87 28731705-8 2017 Block copolymers with PEG as a nonresponsive water-soluble block can self-assemble into well-defined polymersomes with narrow size distribution. copolymers 6-16 progestagen associated endometrial protein Homo sapiens 22-25 32264220-4 2017 During micellization, pi-pi stacking occurred between Dox/alpha-TOS and imidazole rings of PTH copolymers inducing a regular and tight arrangement of copolymers and drugs to form rod-like micelles, thus efficiently increasing the drug loading and encapsulation efficiency. copolymers 95-105 parathyroid hormone Homo sapiens 91-94 28828864-6 2017 The resultant copolymers self-assembled into nanoparticles under physiological condition, with HLAH in cores protected by PEG shells. copolymers 14-24 major histocompatibility complex, class I, H (pseudogene) Homo sapiens 95-99 27537672-5 2017 Copolymers were loaded with regular insulin by modified double emulsion method. copolymers 0-10 insulin Homo sapiens 36-43 28352902-2 2017 Poly(methyl methacrylate)-grad-(styrene) (PMMA-grad-PSt) copolymers were synthesized in semi-batch mode using nitroxide-mediated polymerization (NMP) with varied monomer injection protocols to produce varied diffuse interfaces (number average molecular weights (Mn) ranged from 62 000 g mol-1 to 94 000 g mol-1 with dispersities (D) between 1.35 and 1.59). copolymers 57-67 sulfotransferase family 1A member 1 Homo sapiens 52-55 28635174-2 2017 Herein, reliable, fab-compatible, and ultrafast directed self-assembly of high-chi block copolymers is achieved with intense flash light. copolymers 89-99 FA complementation group B Homo sapiens 18-21 28688213-0 2017 Multivalent methionine-functionalized biocompatible block copolymers for targeted small interfering RNA delivery and subsequent reversal effect on adriamycin resistance in human breast cancer cell line MCF-7/ADR. copolymers 58-68 aldo-keto reductase family 1 member B Homo sapiens 208-211 27756682-3 2017 The structure of the copolymers was characterized by H NMR, FTIR, DSC and GPC techniques. copolymers 21-31 glycophorin C (Gerbich blood group) Homo sapiens 74-77 28415430-3 2017 These I-PLAU copolymers possessed sufficient radiopacity, in vitro non-cytotoxicity with human adipose-derived stem cells, and in vivo biocompatibility and degradability in rabbit model via intramuscular implantation. copolymers 13-23 plasminogen activator, urokinase Homo sapiens 8-12 28358515-7 2017 Importantly, the CA4 conjugated copolymers displayed excellent level of antiangiogenic activity as deduced from in vitro endothelial cell tube formation assay using HUVECs. copolymers 32-42 carbonic anhydrase 4 Homo sapiens 17-20 28535473-1 2017 Novel comb-shaped amphiphilic copolymers based on methoxy poly(ethylene glycol)-b-[poly(epsilon-caprolactone)-g-poly(methacrylic acid)] (MPCL-g-pMAA), were synthesized via ring opening polymerization (ROP) and atom transfer radical polymerization (ATRP) for drug delivery systems. copolymers 30-40 C-type lectin domain family 4 member D Homo sapiens 137-141 28561240-3 2017 The aim of this study was to develop polymersomes using biodegradable copolymers for delivery of bovine serum albumin (BSA) as a model protein. copolymers 70-80 albumin Homo sapiens 104-117 28384619-0 2017 pH responsive micelles based on copolymers mPEG-PCL-PDEA: The relationship between composition and properties. copolymers 32-42 phosphodiesterase 6A Homo sapiens 52-56 28384619-2 2017 In this study, copolymers methoxy-poly (ethylene glycol)-b-poly (epsilon-caprolactone)-b-poly (diethylaminoethyl methacrylate) (mPEG-PCL-PDEA) were designed and synthesized to investigate the relationship between number of pH responsive units and micelle properties. copolymers 15-25 phosphodiesterase 6A Homo sapiens 137-141 28384619-6 2017 The results showed that the micelle properties including pH sensitivity, cytotoxicity and drug loading/releasing performance, were related to PDEA units in copolymers. copolymers 156-166 phosphodiesterase 6A Homo sapiens 142-146 28374684-1 2017 Thermal scanning probe lithography (t-SPL) is applied to the fabrication of chemical guiding patterns for directed self-assembly (DSA) of block copolymers (BCP). copolymers 144-154 sphingosine-1-phosphate lyase 1 Homo sapiens 38-41 28063990-3 2017 Through the straightforward mixing of two block copolymers, the level of gene knockdown was easily optimized to achieve the maximum level of GAPDH protein silencing in NIH/3T3 cells (~70%) using a single siRNA dose. copolymers 48-58 glyceraldehyde-3-phosphate dehydrogenase Mus musculus 141-146 28236696-3 2017 PLA and PCL reacted with LTI during processing in a Brabender twin screw internal mixer to produce block copolymers in-situ. copolymers 105-115 polycystin 2 like 1, transient receptor potential cation channel Homo sapiens 8-11 28088077-2 2017 Our long term goal is to develop cationic, amphiphilic copolymers (poly (lactide-co-glycolide)-g-polyethylenimine, PgP) for combinatorial delivery of therapeutic nucleic acids (TNAs) and drugs targeting these different barriers. copolymers 55-65 phosphoglycolate phosphatase Rattus norvegicus 115-118 27419808-2 2017 In this study, a library of eight bottle-brush copolymers were synthesized to mimic the structure and function of lubricin. copolymers 47-57 proteoglycan 4 Homo sapiens 114-122 30970739-0 2017 Characterization of Comb-Shaped Copolymers by Multidetection SEC, DLS and SANS. copolymers 32-42 USH1 protein network component sans Homo sapiens 74-78 28169384-0 2017 Characterisation of hydration and nanophase separation during the temperature response in hydrophobic/hydrophilic elastin-like polypeptide (ELP) diblock copolymers. copolymers 153-163 nuclear receptor subfamily 5 group A member 1 Homo sapiens 114-138 28169384-0 2017 Characterisation of hydration and nanophase separation during the temperature response in hydrophobic/hydrophilic elastin-like polypeptide (ELP) diblock copolymers. copolymers 153-163 nuclear receptor subfamily 5 group A member 1 Homo sapiens 140-143 27758038-1 2017 In this contribution, amphiphilic star copolymers (H40-star-PCL-a-PEG) with an H40 hyperbranched polyester core and poly(epsilon-caprolactone)-a-poly(ethylene glycol) copolymer arms linked with acetal groups are synthesized using ring-opening polymerization and a copper (I)-catalyzed alkyne-azide cycloaddition click reaction. copolymers 39-49 progestagen associated endometrial protein Homo sapiens 66-69 28121419-1 2017 Vinylidene fluoride (VDF)-based copolymers bearing pendant phosphonic acid function for potential application as anticorrosion coatings were synthesized via free radical copolymerization of VDF with a new phosphorus containing 2-trifluoromethacrylate monomer, (dimethoxyphosphoryl)methyl 2-(trifluoromethyl)acrylate (MAF-DMP). copolymers 32-42 MAF bZIP transcription factor Homo sapiens 317-320 28150934-3 2017 Four dyes with varying pi-conjugation (phenyl, naphthyl) and donor groups (-OMe, -NMe2) were coupled to PLLA-PEG block copolymers (~11 kDa) by a postpolymerization Mitsunobu reaction. copolymers 119-129 NME/NM23 nucleoside diphosphate kinase 2 Homo sapiens 82-86 30970709-8 2017 It is proven that the aqueous solution properties of the copolymers, with specific interest in their thermoresponsive properties, are influenced by the architecture, with the ABC and A(BC) ones to show clear sol-gel transition. copolymers 57-67 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 175-178 27520726-2 2017 The new polymalic acid-based mini nanodrug copolymers are synthesized and specifically characterized to inhibit growth of HER2+ breast cancer. copolymers 43-53 erb-b2 receptor tyrosine kinase 2 Homo sapiens 122-126 27612790-1 2016 A water resistant surface was first obtained by immobilizing hydrophobic copolymers, poly (styrene-co-glycidyl methacrylate) (PSG), with functional groups on soy protein isolate (SPI) films. copolymers 73-83 pregnancy specific beta-1-glycoprotein 5 Homo sapiens 126-129 27933999-1 2016 A new and highly regioselective direct C-H arylation polymerization (DARP) methodology enables the reproducible and sustainable synthesis of high-performance pi-conjugated photovoltaic copolymers. copolymers 185-195 ankyrin repeat domain 23 Homo sapiens 69-73 27933999-2 2016 Unlike traditional Stille polycondensation methods for producing photovoltaic copolymers, this DARP protocol eliminates the need for environmentally harmful, toxic organotin compounds. copolymers 78-88 ankyrin repeat domain 23 Homo sapiens 95-99 27933999-4 2016 Using this DARP protocol, several representative copolymers are synthesized in excellent yields and high molecular masses. copolymers 49-59 ankyrin repeat domain 23 Homo sapiens 11-15 27933999-5 2016 The DARP-derived copolymers are benchmarked versus Stille-derived counterparts by close comparison of optical, NMR spectroscopic, and electrochemical properties, all of which indicate great chemical similarity and no significant detectable structural defects in the DARP copolymers. copolymers 17-27 ankyrin repeat domain 23 Homo sapiens 4-8 27933999-8 2016 For the first time, polymer solar cells fabricated using DARP-derived copolymers exhibit solar cell performances rivalling or exceeding those achieved with Stille-derived materials. copolymers 70-80 ankyrin repeat domain 23 Homo sapiens 57-61 27612790-1 2016 A water resistant surface was first obtained by immobilizing hydrophobic copolymers, poly (styrene-co-glycidyl methacrylate) (PSG), with functional groups on soy protein isolate (SPI) films. copolymers 73-83 chromogranin A Homo sapiens 179-182 27612790-2 2016 XPS and AFM results showed that PSG copolymers were immobilized on the film by chemical bonding, and formed a rough surface with some bumps because of the segregation of two different phases on PSG copolymers. copolymers 36-46 pregnancy specific beta-1-glycoprotein 5 Homo sapiens 32-35 27612790-2 2016 XPS and AFM results showed that PSG copolymers were immobilized on the film by chemical bonding, and formed a rough surface with some bumps because of the segregation of two different phases on PSG copolymers. copolymers 36-46 pregnancy specific beta-1-glycoprotein 5 Homo sapiens 194-197 27612790-2 2016 XPS and AFM results showed that PSG copolymers were immobilized on the film by chemical bonding, and formed a rough surface with some bumps because of the segregation of two different phases on PSG copolymers. copolymers 198-208 pregnancy specific beta-1-glycoprotein 5 Homo sapiens 32-35 27762277-5 2016 Consistently, cosedimentation experiments using copolymers of actin and actin-S1 fusion protein demonstrated that the fusion protein affects the neighboring actin protomers, reducing their affinity for cofilin. copolymers 48-58 cofilin 1 Homo sapiens 202-209 26829568-4 2016 Molecular weight analysis results indicated that the uricase-PEG-PSA conjugate was linked with 2.5 copolymers for each uricase unit. copolymers 99-109 urate oxidase (pseudogene) Homo sapiens 53-60 26829568-4 2016 Molecular weight analysis results indicated that the uricase-PEG-PSA conjugate was linked with 2.5 copolymers for each uricase unit. copolymers 99-109 urate oxidase (pseudogene) Homo sapiens 119-126 27516248-1 2016 Noble copolymers from xanthan gum (XG) and poly(acrylic acid) (PAA) were synthesised through surfactant mediated graft copolymerization. copolymers 6-16 OTU deubiquitinase with linear linkage specificity Homo sapiens 30-33 27564064-3 2016 The block copolymers were successfully obtained via click reaction to introduce peptide (alkynyl-GPLGVRGDG) into the end of PEG for initiating ring-opening polymerization of beta-benzyl l-aspartate N-carboxyanhydride (BLA-NCA) by terminal amino groups followed by partial hydrolysis of PBLA segments. copolymers 10-20 CEA cell adhesion molecule 4 Homo sapiens 222-225 27676451-7 2016 (salen)CrX complexes accompanied by onium salts exhibited high activity and selectivity for COS/epoxide copolymerization under mild conditions, affording copolymers with >99% monothiocarbonate units and high tail-to-head content up to 99%. copolymers 154-164 cone-rod homeobox Homo sapiens 7-10 32263635-0 2016 PCL-PEG graft copolymers with tunable amphiphilicity as efficient drug delivery systems. copolymers 14-24 PHD finger protein 1 Homo sapiens 0-3 32263635-2 2016 For this aim, novel amphiphilic poly(epsilon-caprolactone)-g-poly(ethylene glycol) (PCL-g-PEG) copolymers with well-controlled design were synthesized by thiol-yne photochemistry. copolymers 95-105 PHD finger protein 1 Homo sapiens 84-87 27303948-3 2016 Here, we discuss detailed insights on how the thermo-mechanical properties of tailor-made copolymers govern the tensile properties in bioinspired CNF/polymer settings, hence at high fractions of reinforcements and under nanoconfinement conditions for the polymers. copolymers 90-100 NPHS1 adhesion molecule, nephrin Homo sapiens 146-149 27434113-5 2016 Drug-loading efficiency of nanoparticles from copolymers with compositions of mPEG1-PCL1, mPEG2-PCL2, and mPEG3-PCL3 were 14.43%, 19.8%, and 12.33% respectively. copolymers 46-56 mesoderm specific transcript Mus musculus 78-83 27434113-5 2016 Drug-loading efficiency of nanoparticles from copolymers with compositions of mPEG1-PCL1, mPEG2-PCL2, and mPEG3-PCL3 were 14.43%, 19.8%, and 12.33% respectively. copolymers 46-56 PHD finger protein 1 Mus musculus 84-88 27232763-5 2016 We also observed that when P85 and P188 poloxamers interacted with damaged membranes that contained pores, the hydrophobic blocks of copolymers penetrated into the membrane in the vicinity of the pore and compressed the membrane. copolymers 133-143 phosphoinositide-3-kinase regulatory subunit 2 Homo sapiens 27-30 27426110-0 2016 Thermoresponsive behavior of micellar aggregates from end-functionalized PnBA-b-PNIPAM-COOH block copolymers and their complexes with lysozyme. copolymers 98-108 lysozyme Homo sapiens 134-142 26607767-10 2016 STATEMENT OF SIGNIFICANCE: Herein, novel bioreducible RAFT and ROP double-head agent was first reported for the synthesis of cRGDfK-polycarboxybetaine methacrylate-SS-polycaprolactone zwitterionic block copolymers (cRGD-PCB-SS-PCL, termed as cRGD-PCSSL) through controllable polymerization methods. copolymers 203-213 pyruvate carboxylase Homo sapiens 220-223 27372424-2 2016 Herein, we developed multi-block HPMA copolymers with backbones that are susceptible to cleavage by cathepsin S, a protease that is abundantly expressed in tissues of the mononuclear phagocyte system (MPS). copolymers 38-48 cathepsin S Homo sapiens 100-111 30974618-0 2016 Tailoring the Static and Dynamic Mechanical Properties of Tri-Block Copolymers through Molecular Dynamics Simulation. copolymers 68-78 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 58-61 30974618-1 2016 Although the research of the self-assembly of tri-block copolymers has been carried out widely, little attention has been paid to study the mechanical properties and to establish its structure-property relation, which is of utmost significance for its practical applications. copolymers 56-66 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 46-49 27207042-8 2016 Our results suggested that PLCL copolymers with tunable degradation rate as carriers for ciprofloxacin lactate could be used as a promising long-term antibacterial coating for ureteral stents. copolymers 32-42 phospholipase C like 1 (inactive) Homo sapiens 27-31 27098211-4 2016 The obtained copolymers (P1 and P2) having desirable water solubility were well-characterized by infrared spectroscopy (IR), nuclear magnetic resonance (NMR), gel permeation chromatography (GPC), UV-Vis absorption spectroscopy, and photoluminescence spectroscopy. copolymers 13-23 crystallin gamma F, pseudogene Homo sapiens 25-34 27462975-2 2016 MATERIALS & METHODS: IFN-alpha and pegylated IFN-alpha (PEG-IFN-alpha) were encapsulated by poly(lactic-co-glycolic acid) (PLGA) and pegylated PLGA (PEG-PLGA) copolymers using double emulsion solvent evaporation method. copolymers 163-173 interferon alpha 1 Homo sapiens 25-34 27462975-2 2016 MATERIALS & METHODS: IFN-alpha and pegylated IFN-alpha (PEG-IFN-alpha) were encapsulated by poly(lactic-co-glycolic acid) (PLGA) and pegylated PLGA (PEG-PLGA) copolymers using double emulsion solvent evaporation method. copolymers 163-173 interferon alpha 1 Homo sapiens 49-58 27462975-2 2016 MATERIALS & METHODS: IFN-alpha and pegylated IFN-alpha (PEG-IFN-alpha) were encapsulated by poly(lactic-co-glycolic acid) (PLGA) and pegylated PLGA (PEG-PLGA) copolymers using double emulsion solvent evaporation method. copolymers 163-173 interferon alpha 1 Homo sapiens 49-58 27145021-3 2016 This report describes a new type of self-assembling polyethylene glycol-phosphoethanolamine-based copolymers (PEG-pp-PE) which showed both the matrix metalloproteinase 2 (MMP2)-sensitive tumor-targeted drug delivery and ability to inhibit the P-glycoprotein (P-gp)-mediated drug efflux. copolymers 98-108 matrix metallopeptidase 2 Homo sapiens 143-169 26993199-6 2016 CONCLUSIONS: In copolymers of NF-LH, NF-H shifts the I(G) to N(G) transition to nearer physiological salt concentrations, as compared to NF-M in copolymers of NF-LM. copolymers 145-155 neurofilament medium chain Bos taurus 137-141 26930034-5 2016 The pKb values of three copolymers were found to be around 6.1-6.3 by potentiometric titration test, showing the satisfied pH-sensitivity. copolymers 24-34 AKT serine/threonine kinase 1 Homo sapiens 4-7 27145021-3 2016 This report describes a new type of self-assembling polyethylene glycol-phosphoethanolamine-based copolymers (PEG-pp-PE) which showed both the matrix metalloproteinase 2 (MMP2)-sensitive tumor-targeted drug delivery and ability to inhibit the P-glycoprotein (P-gp)-mediated drug efflux. copolymers 98-108 matrix metallopeptidase 2 Homo sapiens 171-175 27145021-3 2016 This report describes a new type of self-assembling polyethylene glycol-phosphoethanolamine-based copolymers (PEG-pp-PE) which showed both the matrix metalloproteinase 2 (MMP2)-sensitive tumor-targeted drug delivery and ability to inhibit the P-glycoprotein (P-gp)-mediated drug efflux. copolymers 98-108 ATP binding cassette subfamily B member 1 Homo sapiens 243-257 27145021-3 2016 This report describes a new type of self-assembling polyethylene glycol-phosphoethanolamine-based copolymers (PEG-pp-PE) which showed both the matrix metalloproteinase 2 (MMP2)-sensitive tumor-targeted drug delivery and ability to inhibit the P-glycoprotein (P-gp)-mediated drug efflux. copolymers 98-108 ATP binding cassette subfamily B member 1 Homo sapiens 259-263 27145021-5 2016 We found that the whole structure (PEG-peptide-lipid) rather than any parts of the copolymers was key for the P-gp inhibition and a delicate balance between the hydrophilic and lipophilic segments of the PEG-pp-PE copolymers was needed for better modulating the P-gp-mediated drug efflux. copolymers 83-93 ATP binding cassette subfamily B member 1 Homo sapiens 110-114 27465655-0 2016 Phase behavior of ABC-type triple-hydrophilic block copolymers in aqueous solutions. copolymers 52-62 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 18-21 30979331-2 2016 In this regard, the present work investigated the effect of copolymers on the conformation and thermal stability of bovine serum albumin (BSA) with the aid of biophysical techniques such as fluorescence spectroscopy, circular dichroism (CD) spectroscopy and differential scanning calorimetry (DSC). copolymers 60-70 albumin Homo sapiens 129-136 27188541-0 2016 HBP Builder: A Tool to Generate Hyperbranched Polymers and Hyperbranched Multi-Arm Copolymers for Coarse-grained and Fully Atomistic Molecular Simulations. copolymers 83-93 heme binding protein 1 Homo sapiens 0-3 33440481-0 2016 Cationic Galactose-Conjugated Copolymers for Epidermal Growth Factor (EGFR) Knockdown in Cervical Adenocarcinoma. copolymers 30-40 epidermal growth factor Homo sapiens 45-68 33440481-0 2016 Cationic Galactose-Conjugated Copolymers for Epidermal Growth Factor (EGFR) Knockdown in Cervical Adenocarcinoma. copolymers 30-40 epidermal growth factor Homo sapiens 70-74 26952455-1 2016 The aim of the present study was to evaluate a library of poly-L-lysine (PLL)-graft (g)-polyethylene glycol (PEG) copolymers for the ability to encapsulate effectively a model protein, bovine serum albumin (BSA), and to characterize the stability and protein function of the resulting nanoparticle. copolymers 114-124 albumin Homo sapiens 192-205 26991820-4 2016 Evidence for the formation of block copolymers was obtained from solubility differences, GPC, and DOSY-NMR studies. copolymers 36-46 glycophorin C (Gerbich blood group) Homo sapiens 89-92 28944290-3 2016 We synthesized two types of sensors by linking the near-infrared fluorophore IRDye 800CW to macromolecular graft copolymers of methoxy polyethylene glycol and polylysine (MPEG-gPLL) with varying degrees of MPEGylation and studied their fragmentation induced by trypsin, elastase, plasmin and cathepsins (B,S,L,K). copolymers 113-123 plasminogen Homo sapiens 280-287 26906431-4 2016 All of the copolymers have been characterized by (1)H and (13)C NMR and FTIR spectroscopies and TGA/DSC. copolymers 11-21 T-box transcription factor 1 Homo sapiens 96-99 26911417-2 2016 The novel copolymers were characterized by (1)H-NMR and TGA. copolymers 10-20 T-box transcription factor 1 Homo sapiens 56-59 26931173-1 2016 We report the behaviour of thermoresponsive block copolymers of n-butyl acrylate and N-alkyl acrylamides in [C2mim][NTf2]. copolymers 50-60 nuclear transport factor 2 Homo sapiens 116-120 26906431-4 2016 All of the copolymers have been characterized by (1)H and (13)C NMR and FTIR spectroscopies and TGA/DSC. copolymers 11-21 desmocollin 3 Homo sapiens 100-103 27451792-2 2016 Block copolymers are characterized by GPC and IHNMR. copolymers 6-16 glycophorin C (Gerbich blood group) Homo sapiens 38-41 26773613-4 2016 At first, three different block copolymers were prepared by polymerizing mixture of NIPA and PEGMEA (with varying mole ratio) in presence of poly(tert-butyl acrylate) (PtBA) macro chain transfer agent. copolymers 32-42 zinc finger C3HC-type containing 1 Homo sapiens 84-88 26926103-3 2016 The copolymers (FA-PLL(DCA)-PLC) spontaneously crosslinked in situ to form redox and pH dual responsive FA-PLL(DCA)-PLC nanoparticles (FD-NPs), which had a reversible zeta potential around -30 mV at pH 7.4, but switched to +15 mV at pH 5.0. copolymers 4-14 heparan sulfate proteoglycan 2 Homo sapiens 28-31 26833583-3 2016 In this work, the relevance of beta-CD permethylation has been addressed by preparing and evaluating two series of copolymers of the cationic N-ethyl pyrrolidine methacrylamide (EPA) and styrenic units bearing pendant hydroxylated and permethylated beta-CDs (HCDSt and MeCDSt, respectively). copolymers 115-125 beta-carotene oxygenase 1 Mus musculus 31-38 26932684-1 2016 We synthesized two novel ultra low bandgap donor-acceptor (D-A) copolymers (E(g) <= 1.2 eV), containing the thiadiazoloquinoxaline unit as the main electron accepting unit (A) and benzodithiophene (BDT) and dithienosilole (DTS) as different donor units (D), denoted as P1 and P2, respectively, using the cross-coupling Stille reaction. copolymers 64-74 crystallin gamma F, pseudogene Homo sapiens 272-281 26926103-3 2016 The copolymers (FA-PLL(DCA)-PLC) spontaneously crosslinked in situ to form redox and pH dual responsive FA-PLL(DCA)-PLC nanoparticles (FD-NPs), which had a reversible zeta potential around -30 mV at pH 7.4, but switched to +15 mV at pH 5.0. copolymers 4-14 heparan sulfate proteoglycan 2 Homo sapiens 116-119 25630439-2 2016 AIM: This article aims to investigate the effect of poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) block copolymers with a wide range of biomedical and pharmaceutical applications on apoptosis and/or cell immortalization, by flow cytometry and multiplex RT-PCR for bax, bcl-2, and human telomerase reverse transcriptase (hTERT). copolymers 111-121 telomerase reverse transcriptase Homo sapiens 327-332 26927835-4 2016 These results indicate that for a sufficiently hydrophobic and high molar mass ELP block, there is a great deal of design latitude in the construction of fusion protein block copolymers for self-assembling nanomaterials. copolymers 175-185 nuclear receptor subfamily 5 group A member 1 Homo sapiens 79-82 30979172-4 2016 The structures and properties of the obtained copolymers were characterized by FT-IR, (1H)13C NMR, GPC, DSC, and water contact angle. copolymers 46-56 glycophorin C (Gerbich blood group) Homo sapiens 99-102 30979172-4 2016 The structures and properties of the obtained copolymers were characterized by FT-IR, (1H)13C NMR, GPC, DSC, and water contact angle. copolymers 46-56 desmocollin 3 Homo sapiens 104-107 25630439-2 2016 AIM: This article aims to investigate the effect of poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) block copolymers with a wide range of biomedical and pharmaceutical applications on apoptosis and/or cell immortalization, by flow cytometry and multiplex RT-PCR for bax, bcl-2, and human telomerase reverse transcriptase (hTERT). copolymers 111-121 protoporphyrinogen oxidase Homo sapiens 100-103 26571300-3 2016 In the current study, the Monte Carlo technique was applied in a lattice model to study the self-assembly of ABC triblock copolymers under 3D soft confinement, which corresponds to the self-assembly of block copolymers confined in emulsion droplets. copolymers 122-132 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 109-112 25630439-2 2016 AIM: This article aims to investigate the effect of poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) block copolymers with a wide range of biomedical and pharmaceutical applications on apoptosis and/or cell immortalization, by flow cytometry and multiplex RT-PCR for bax, bcl-2, and human telomerase reverse transcriptase (hTERT). copolymers 111-121 BCL2 associated X, apoptosis regulator Homo sapiens 271-274 25630439-2 2016 AIM: This article aims to investigate the effect of poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) block copolymers with a wide range of biomedical and pharmaceutical applications on apoptosis and/or cell immortalization, by flow cytometry and multiplex RT-PCR for bax, bcl-2, and human telomerase reverse transcriptase (hTERT). copolymers 111-121 BCL2 apoptosis regulator Homo sapiens 276-281 25630439-2 2016 AIM: This article aims to investigate the effect of poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) block copolymers with a wide range of biomedical and pharmaceutical applications on apoptosis and/or cell immortalization, by flow cytometry and multiplex RT-PCR for bax, bcl-2, and human telomerase reverse transcriptase (hTERT). copolymers 111-121 telomerase reverse transcriptase Homo sapiens 293-325 25630439-4 2016 CONCLUSIONS: PEO-PPO block copolymers-considered safe for human use-can drastically alter gene expression profiles of genes related to apoptosis/cell proliferation. copolymers 27-37 protoporphyrinogen oxidase Homo sapiens 17-20 26481428-6 2016 From the spectroscopy results, the copolymers affected the local microstructure of fibrinogen. copolymers 35-45 fibrinogen beta chain Homo sapiens 83-93 26784333-2 2016 MATERIALS & METHODS: Generation 1.0 polyamidoamine (PAMAM G1)-based copolymers (PGP) and RGD modified PGP (PGP-RGD) were synthesized and its properties were evaluated. copolymers 72-82 phosphoglycolate phosphatase Homo sapiens 84-87 26760051-2 2016 Here, we report on the structure and mechanics of highly asymmetric and thermodynamically stable soft-hard lamellar structures self-assembled from optimally designed PS1-(PI-b-PS2)3 miktoarm star block copolymers. copolymers 202-212 taste 2 receptor member 62 pseudogene Homo sapiens 166-169 26760051-2 2016 Here, we report on the structure and mechanics of highly asymmetric and thermodynamically stable soft-hard lamellar structures self-assembled from optimally designed PS1-(PI-b-PS2)3 miktoarm star block copolymers. copolymers 202-212 taste 2 receptor member 64 pseudogene Homo sapiens 176-179 26636714-3 2016 We found that the PEG5K-VE4-DET20 nanoassemblies could entrap paclitaxel for an extended period and burst release the drug in the presence of cathepsin B, demonstrating the biodegradability of the copolymers. copolymers 197-207 cathepsin B Mus musculus 142-153 26463014-2 2016 Herein, we report a new series of biodegradable, fluorescence imaging-enabled copolymers, biodegradable photoluminescent poly(lactide-co-glycolide) (BPLP-co-PLGA). copolymers 78-88 opiorphin prepropeptide Homo sapiens 149-153 26760034-5 2016 Our research group developed and characterized oligo(poly(ethylene glycol)fumarate)/sodium methacrylate (OPF/SMA) charged copolymers as biocompatible hydrogel matrices. copolymers 122-132 survival of motor neuron 1, telomeric Homo sapiens 109-112 26676863-0 2016 Doxorubicin-loaded micelles based on multiarm star-shaped PLGA-PEG block copolymers: influence of arm numbers on drug delivery. copolymers 73-83 progestagen associated endometrial protein Homo sapiens 63-66 26676863-1 2016 Star-shaped block copolymers based on poly(D,L-lactide-co-glycolide) (PLGA) and poly(ethylene glycol) (PEG) (st-PLGA-PEG) were synthesized with structural variation on arm numbers in order to investigate the relationship between the arm numbers of st-PLGA-PEG copolymers and their micelle properties. copolymers 18-28 progestagen associated endometrial protein Homo sapiens 80-107 26676863-1 2016 Star-shaped block copolymers based on poly(D,L-lactide-co-glycolide) (PLGA) and poly(ethylene glycol) (PEG) (st-PLGA-PEG) were synthesized with structural variation on arm numbers in order to investigate the relationship between the arm numbers of st-PLGA-PEG copolymers and their micelle properties. copolymers 18-28 progestagen associated endometrial protein Homo sapiens 103-106 26676863-1 2016 Star-shaped block copolymers based on poly(D,L-lactide-co-glycolide) (PLGA) and poly(ethylene glycol) (PEG) (st-PLGA-PEG) were synthesized with structural variation on arm numbers in order to investigate the relationship between the arm numbers of st-PLGA-PEG copolymers and their micelle properties. copolymers 18-28 progestagen associated endometrial protein Homo sapiens 117-120 26676863-3 2016 The critical micelle concentration decreased with increasing arm numbers in st-PLGA-PEG copolymers. copolymers 88-98 progestagen associated endometrial protein Homo sapiens 84-87 26676863-7 2016 The results suggest that structural tailoring of arm numbers from st-PLGA-PEG copolymers could provide a new strategy for designing drug carriers of high efficiency. copolymers 78-88 progestagen associated endometrial protein Homo sapiens 74-77 26676863-8 2016 Structural tailoring of arm numbers from star shaped-PLGA-PEG copolymers (3-arm/4-arm/6-arm-PLGA-PEG) could provide a new strategy for designing drug carriers of high efficiency. copolymers 62-72 progestagen associated endometrial protein Homo sapiens 58-61 26676863-8 2016 Structural tailoring of arm numbers from star shaped-PLGA-PEG copolymers (3-arm/4-arm/6-arm-PLGA-PEG) could provide a new strategy for designing drug carriers of high efficiency. copolymers 62-72 progestagen associated endometrial protein Homo sapiens 97-100 26320543-6 2015 The copolymers were capable of restoring the transduction of hMSCs with rAAV in conditions of gene transfer inhibition, i.e. in the presence of heparin or of a specific antibody directed against the rAAV capsid, enabling effective therapeutic delivery of a chondrogenic sox9 sequence leading to an enhanced chondrocyte differentiation of the cells. copolymers 4-14 SRY-box transcription factor 9 Homo sapiens 270-274 26393405-8 2015 Initially, mitochondrial galectin-3 weakened Dox-induced mitochondrial damage; however, as time progressed, G3-C12 active-mediation allowed increasing amounts of Dox to be delivered to the mitochondria, which eventually induced higher level of apoptosis than nontargeted copolymers. copolymers 271-281 galectin 3 Homo sapiens 25-35 26625137-8 2015 A PTFE dispersion containing P123 showed the maximum wettability and lowest sedimentation among the series of block copolymers introduced, which is attributed to faster diffusion kinetics and a higher PPO contribution fostering faster adsorption at the PTFE surface. copolymers 116-126 protoporphyrinogen oxidase Homo sapiens 201-204 26456723-4 2015 Retarded protein migration into acrylamide gels stained for BChE activity was noted with all copolymers as the copolymer-to-protein ratio was increased. copolymers 93-103 butyrylcholinesterase Homo sapiens 60-64 26280750-8 2015 The results are helpful for designing coil-comb copolymers and obtaining the ordered morphology. copolymers 48-58 coilin Homo sapiens 38-42 26198460-0 2015 Study on Self-Assembled Well-Defined PEG Graft Copolymers as Efficient Drug-Loaded Nanoparticles for Anti-Inflammatory Therapy. copolymers 47-57 progestagen associated endometrial protein Homo sapiens 37-40 26291587-6 2015 Micelles prepared using high molecular weight block copolymers exhibited good colloidal stability, encapsulation efficiency and insulin release characteristics. copolymers 52-62 insulin Homo sapiens 128-135 26218495-1 2015 Though l-arginine-containing polymers show versatile biological functions, a precisely controlled synthesis of poly(ethylene glycol)-b-poly(l-arginine) (PEG-b-PArg) block copolymers has not been reported. copolymers 171-181 poly(ADP-ribose) glycohydrolase Homo sapiens 159-163 26218495-2 2015 Here, an effective method for the synthesis of PEG-b-PArg block copolymers is developed. copolymers 64-74 poly(ADP-ribose) glycohydrolase Homo sapiens 53-57 26258607-5 2015 The physical and chemical properties of these polymers have a great impact on gene delivery efficacy into hepatocytes, as such block copolymers are found to form more stable complexes with plasmid and have high gene delivery efficiency into ASGPR expressing hepatocytes. copolymers 133-143 asialoglycoprotein receptor 1 Homo sapiens 241-246 26343286-5 2015 The triblock copolymers, PLLA-co-PEG-co-PLLA and PDLA-co-PEG-co-PDLA, were employed for square patterning with the inkjet system, which produced thin films. copolymers 13-23 PDON2 Homo sapiens 49-53 26343286-5 2015 The triblock copolymers, PLLA-co-PEG-co-PLLA and PDLA-co-PEG-co-PDLA, were employed for square patterning with the inkjet system, which produced thin films. copolymers 13-23 PDON2 Homo sapiens 64-68 26194248-1 2015 We previously elucidated that ATP-binding cassette subfamily B member 1 (ABCB1) mediates the efflux of doxorubicin-conjugated block copolymers from HeLa cells. copolymers 132-142 ATP binding cassette subfamily B member 1 Homo sapiens 30-71 26194248-1 2015 We previously elucidated that ATP-binding cassette subfamily B member 1 (ABCB1) mediates the efflux of doxorubicin-conjugated block copolymers from HeLa cells. copolymers 132-142 ATP binding cassette subfamily B member 1 Homo sapiens 73-78 32262674-4 2015 The molecular weight of the synthetic hybrid copolymers was determined by GPC and MALDI-ToF mass spectrometry. copolymers 45-55 glycophorin C (Gerbich blood group) Homo sapiens 74-77 26115534-1 2015 Interactions of X-shaped poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) block copolymers with cell membranes were investigated recording the pi-A isotherms of monolayer systems of dipalmitoylphosphatidylcholine (DPPC):cholesterol 100:0; 80:20 and 60:40 mol ratio and evaluating the capability of the copolymers to trigger haemolysis or to protect from haemolytic agents. copolymers 84-94 protoporphyrinogen oxidase Homo sapiens 73-76 26134273-4 2015 Amphiphilic block copolymers, omega-methoxypoly(ethylene glycol)-b-(N-(2-benzoyloxypropyl) methacrylamide) (PEG-HPMA-Bz) were synthesized and characterized by (1)H NMR and GPC. copolymers 18-28 glycophorin C (Gerbich blood group) Homo sapiens 172-175 26068280-1 2015 Alginate-based amphiphilic graft copolymers were synthesized by single electron transfer living radical polymerization (SET-LRP), forming stable micelles during polymerization induced self-assembly (PISA). copolymers 33-43 LDL receptor related protein 1 Homo sapiens 124-127 26343620-1 2015 Statistical copolymers of norbornene (NBE) with cyclopentene (CP) were prepared by ring-opening metathesis polymerization, employing the 1st-generation Grubbs" catalyst, in the presence or absence of triphenylphosphine, PPh3. copolymers 12-22 caveolin 1 Homo sapiens 220-224 26225535-4 2015 We have used radical polymerization to synthesize copolymers with controlled EA/MA ratio, seeking to modulate the degree of FN fibrillogenesis. copolymers 50-60 fibronectin 1 Mus musculus 124-126 26225535-8 2015 Myogenic differentiation was enhanced on the copolymers with higher EA content, i.e. more interconnected FN fibrils. copolymers 45-55 fibronectin 1 Mus musculus 105-107 26057248-0 2015 The effects of anionic electrolytes and human serum albumin on the LCST of poly(N-isopropylacrylamide)-based temperature-responsive copolymers. copolymers 132-142 albumin Homo sapiens 46-59 25736430-1 2015 Case study of PEO and its PPO-PEO diblock copolymers. copolymers 42-52 twinkle mtDNA helicase Homo sapiens 14-17 25736430-1 2015 Case study of PEO and its PPO-PEO diblock copolymers. copolymers 42-52 protoporphyrinogen oxidase Homo sapiens 26-29 25736430-1 2015 Case study of PEO and its PPO-PEO diblock copolymers. copolymers 42-52 twinkle mtDNA helicase Homo sapiens 30-33 25736430-2 2015 Stability and reorganization in Langmuir films of PEO in PEO homopolymers and PPO-PEO block copolymers were investigated using film balance measurements. copolymers 92-102 protoporphyrinogen oxidase Homo sapiens 78-81 25867524-5 2015 Of particular interests is the distinctly increased field-effect mobility of these copolymers after thermal treatment, which may arise from the enhanced coplanarity and intermolecular ordering of the indigo, isoindigo or diketopyrrolopyrrole units after elimination of the bulky t-Boc side groups. copolymers 83-93 BOC cell adhesion associated, oncogene regulated Homo sapiens 281-284 26030881-1 2015 High free-volume copolymers were prepared via polycondensation with 2,3,5,6,-tetrafluoroterephthalonitrile (TFTPN) in which a portion of the 3,3,3",3"-tetramethyl-1,1"-spirobisindane (TTSBI) of PIM-1 was replaced with dibutyl anthracene maleimide (4bIII). copolymers 17-27 Pim-1 proto-oncogene, serine/threonine kinase Homo sapiens 194-199 26030881-1 2015 High free-volume copolymers were prepared via polycondensation with 2,3,5,6,-tetrafluoroterephthalonitrile (TFTPN) in which a portion of the 3,3,3",3"-tetramethyl-1,1"-spirobisindane (TTSBI) of PIM-1 was replaced with dibutyl anthracene maleimide (4bIII). copolymers 17-27 calcium voltage-gated channel subunit alpha1 B Homo sapiens 249-253 27065492-0 2015 Elastin-like Polypeptide Diblock Copolymers Self-Assemble into Weak Micelles. copolymers 33-43 elastin Homo sapiens 0-7 25807174-4 2015 Within the Langmuir-trough, PEO-b-PPO acts as the most effective amphiphile compared to the other PPO-containing copolymers. copolymers 113-123 protoporphyrinogen oxidase Homo sapiens 98-101 27274605-2 2015 The aim of this work is to design and develop a new tri-leaflet prosthetic heart valve (HV) made from styrenic block copolymers. copolymers 117-127 tRNA-Ile (anticodon AAT) 9-1 Homo sapiens 52-55 25867524-1 2015 A series of donor-acceptor type of pi-conjugated copolymers based on tert-butoxycarbonyl (t-Boc) substituted indigo, isoindigo or diketopyrrolopyrrole as the acceptor unit and a benzodithiophene derivative as the donor unit was designed and synthesized. copolymers 49-59 BOC cell adhesion associated, oncogene regulated Homo sapiens 92-95 25046378-6 2015 All copolymers exhibited excellent resistance to fibrinogen adsorption and adsorbed more albumin than fibrinogen in the competitive adsorption assay, suggesting their good hemocompatibility. copolymers 4-14 fibrinogen beta chain Homo sapiens 49-59 25816726-8 2015 The data showed that drug-loaded copolymers exhibited enhanced cell inhibition toward U87 cells in compared to MCF-7 cells because targeting increased the cytotoxicity of drug-loaded copolymers against integrin alphavbeta3 receptor expressing tumor cells. copolymers 33-43 integrin subunit alpha V Homo sapiens 202-222 25816726-8 2015 The data showed that drug-loaded copolymers exhibited enhanced cell inhibition toward U87 cells in compared to MCF-7 cells because targeting increased the cytotoxicity of drug-loaded copolymers against integrin alphavbeta3 receptor expressing tumor cells. copolymers 183-193 integrin subunit alpha V Homo sapiens 202-222 25611563-0 2015 Aggregation of poly(acrylic acid)-containing elastin-mimetic copolymers. copolymers 61-71 elastin Homo sapiens 45-52 25721090-1 2015 In this paper the three new narrow bandgap D-A conjugated copolymers P1, P2 and P3 based on different weak donor fused thiophene-imidazole containing derivatives and the same benzothiadiazole acceptor unit were synthesized by Stille cross-coupling polymerization and characterized by 1H NMR, elemental analysis, GPC, TGA, DSC. copolymers 58-68 crystallin gamma F, pseudogene Homo sapiens 69-82 25721090-1 2015 In this paper the three new narrow bandgap D-A conjugated copolymers P1, P2 and P3 based on different weak donor fused thiophene-imidazole containing derivatives and the same benzothiadiazole acceptor unit were synthesized by Stille cross-coupling polymerization and characterized by 1H NMR, elemental analysis, GPC, TGA, DSC. copolymers 58-68 glycophorin C (Gerbich blood group) Homo sapiens 312-315 25721090-1 2015 In this paper the three new narrow bandgap D-A conjugated copolymers P1, P2 and P3 based on different weak donor fused thiophene-imidazole containing derivatives and the same benzothiadiazole acceptor unit were synthesized by Stille cross-coupling polymerization and characterized by 1H NMR, elemental analysis, GPC, TGA, DSC. copolymers 58-68 T-box transcription factor 1 Homo sapiens 317-320 25721090-1 2015 In this paper the three new narrow bandgap D-A conjugated copolymers P1, P2 and P3 based on different weak donor fused thiophene-imidazole containing derivatives and the same benzothiadiazole acceptor unit were synthesized by Stille cross-coupling polymerization and characterized by 1H NMR, elemental analysis, GPC, TGA, DSC. copolymers 58-68 desmocollin 3 Homo sapiens 322-325 25721090-4 2015 The highest occupied molecular orbital (HOMO) energy level of all copolymers is deep lying (-5.24 eV and -5.37 eV and -5.25 eV for P1, P2 and P2, respectively) which shows that copolymers have good stability in the air and assured a higher open circuit voltage (Voc) for polymer BHJ solar cells. copolymers 66-76 crystallin gamma F, pseudogene Homo sapiens 131-144 25721090-4 2015 The highest occupied molecular orbital (HOMO) energy level of all copolymers is deep lying (-5.24 eV and -5.37 eV and -5.25 eV for P1, P2 and P2, respectively) which shows that copolymers have good stability in the air and assured a higher open circuit voltage (Voc) for polymer BHJ solar cells. copolymers 177-187 crystallin gamma F, pseudogene Homo sapiens 131-144 32262351-6 2015 These dendritic copolymers exhibited low in vitro cytotoxicity against MCF-7 and SKOV-3 cells with >80% viable cells at the tested polymer concentration below 25 mug mL-1 and also caused no death of the mice in vivo at a dose of 0.75 mg kg-1. copolymers 16-26 2'-5' oligoadenylate synthetase 1B Mus musculus 166-170 25664773-5 2015 For both copolymers, the thermal treatment offsets the low-temperature monomer evolution while still maintaining surface characteristics suitable to induce the perpendicular orientation of the BCPs, thus ultimately extending the range of processing temperatures of the BCP film and consequently speeding the self-organization process. copolymers 9-19 opsin 1, short wave sensitive Homo sapiens 193-196 25569169-3 2015 The obtained NIRF copolymers were characterized by nuclear magnetic resonance (NMR), gel permeation chromatography (GPC), and its was measured by means of micelles dynamic light scattering (DLS), field emission transmission electron microscopy (FETEM), and UV-vis and fluorescence spectrophotometry. copolymers 18-28 interleukin 17B Homo sapiens 13-17 26353724-5 2015 The obtained copolymers showed thermal stabilities, which were characterized by TGA and DSC. copolymers 13-23 T-box transcription factor 1 Homo sapiens 80-83 25238612-2 2014 Attention was paid to CMRP for its unusual high efficiency observed for the control of acrylate and vinyl acetate polymerization that produced homo- and block copolymers with narrow molecular weight distribution and a predictable molecular weight. copolymers 159-169 ATP binding cassette subfamily C member 2 Homo sapiens 22-26 25407963-5 2015 This characteristic has been applied for the development of ELP-based block copolymers that can self-assemble into nanoparticles. copolymers 76-86 nuclear receptor subfamily 5 group A member 1 Homo sapiens 60-63 25403150-2 2014 The obtained copolymers were found to be nonporous spherical microparticles that were able to achieve greater pi-conjugated structure, smaller particle aggregate size, and stronger interaction with Pb(II) ions than poly(m-phenylenediamine) containing only -NH-, -N=, and -NH2. copolymers 13-23 submaxillary gland androgen regulated protein 3B Homo sapiens 198-204 25465016-2 2014 Size-exclusion chromatography (SEC or GPC) has a quasi-monopoly in separation-based characterization methods for polymers, including block copolymers. copolymers 139-149 glycophorin C (Gerbich blood group) Homo sapiens 38-41 25308862-4 2014 When the repulsive interaction between block copolymers and nanoparticles aPA = aPB = 25, the nanoparticles are evenly distributed within the spherical micelles. copolymers 45-55 glutamyl aminopeptidase Homo sapiens 74-77 25308862-4 2014 When the repulsive interaction between block copolymers and nanoparticles aPA = aPB = 25, the nanoparticles are evenly distributed within the spherical micelles. copolymers 45-55 arginyl aminopeptidase Homo sapiens 80-83 25515324-7 2015 Additionally, block copolymers protected siRNAs against endonuclease digestion and facilitated knockdown of glyceraldehyde 3-phosphate dehydrogenase (Gapdh) mRNA expression in murine calvarial preosteoblasts. copolymers 20-30 glyceraldehyde-3-phosphate dehydrogenase Mus musculus 108-148 25515324-7 2015 Additionally, block copolymers protected siRNAs against endonuclease digestion and facilitated knockdown of glyceraldehyde 3-phosphate dehydrogenase (Gapdh) mRNA expression in murine calvarial preosteoblasts. copolymers 20-30 glyceraldehyde-3-phosphate dehydrogenase Mus musculus 150-155 25495869-5 2015 All copolymers, including the hydrophilic PAA parent chain, provided a remarkable protective effect against CAB aggregation during renaturation, and most of them (but not the octadecyl-modified one) markedly enhanced the regain of activity as compared to CAB alone. copolymers 4-14 carbonic anhydrase 2 Homo sapiens 108-111 25495869-7 2015 In the presence of polymers (CAB:polymer of 1:1 w/w ratio) at concentration ~0.6 g L(-1), the radii of the largest complexes were similar to the radii of the copolymers alone, suggesting that the binding of CAB involves one or a few polymer chain(s). copolymers 158-168 carbonic anhydrase 2 Homo sapiens 29-32 25313939-6 2014 The heterogeneous copolymers (PEG/PPG copolymers) obeyed the Doolittle equation, while the homogeneous (PEG/PEG and PPG/PPG) copolymers did not. copolymers 18-28 serglycin Homo sapiens 34-37 24955652-4 2014 The results of qPCR and competitive binding test indicated that the expression level of galectin-3 in two metastatic prostate carcinoma cell lines (PC-3 and DU145 cells) could be significantly suppressed by the addition of G3-C12-modified HPMA copolymers (PG1 and PG2), demonstrating the high affinity of PG1 and PG2 to galectin-3. copolymers 244-254 galectin 3 Homo sapiens 88-98 25317967-3 2014 We herein report the fabrication of ultrasensitive ratiometric fluorescent pHi imaging probes with robust endosomal escaping capability derived from dual dye-labeled pH-responsive block copolymers, which can directly monitor endosomal escape in living cells and quantitatively measure pHi variations during the entire endocytic and endosomolytic processes. copolymers 186-196 glucose-6-phosphate isomerase Homo sapiens 75-78 25317967-3 2014 We herein report the fabrication of ultrasensitive ratiometric fluorescent pHi imaging probes with robust endosomal escaping capability derived from dual dye-labeled pH-responsive block copolymers, which can directly monitor endosomal escape in living cells and quantitatively measure pHi variations during the entire endocytic and endosomolytic processes. copolymers 186-196 glucose-6-phosphate isomerase Homo sapiens 285-288 25121341-6 2014 These copolymers were further conjugated through disulfide bonds to a Her-2 targeting moiety, Her-2 affibody. copolymers 6-16 erb-b2 receptor tyrosine kinase 2 Homo sapiens 70-75 25121341-6 2014 These copolymers were further conjugated through disulfide bonds to a Her-2 targeting moiety, Her-2 affibody. copolymers 6-16 erb-b2 receptor tyrosine kinase 2 Homo sapiens 94-99 25137434-1 2014 This report describes the synthesis of amphiphilic copolymers (ABC-1 and ABC-2) composed of a hydrophilic poly(ethylene glycol) (PEG) block, a central poly(acrylic acid) (PAA) block, and a random copolymer of heptadecafluorodecyl methacrylate (HDFMA) and methyl methacrylate (MMA) forming the hydrophobic block, which are used to form nanodroplets for ultrasound-mediated cell ablation. copolymers 51-61 ATP binding cassette subfamily A member 1 Homo sapiens 63-68 25137434-1 2014 This report describes the synthesis of amphiphilic copolymers (ABC-1 and ABC-2) composed of a hydrophilic poly(ethylene glycol) (PEG) block, a central poly(acrylic acid) (PAA) block, and a random copolymer of heptadecafluorodecyl methacrylate (HDFMA) and methyl methacrylate (MMA) forming the hydrophobic block, which are used to form nanodroplets for ultrasound-mediated cell ablation. copolymers 51-61 ATP binding cassette subfamily A member 2 Homo sapiens 73-78 25942870-1 2014 In this study, Graft copolymers composed of PSf backbones and PEG side chains were synthesized to prepare gas separation membranes with enhancing permeability and selectivity on carbon dioxide separation. copolymers 21-31 insulin like growth factor binding protein 7 Homo sapiens 44-47 24996289-6 2014 Copolymers were loaded with regular insulin by modified double emulsion method with ratio of 1:10. copolymers 0-10 insulin Homo sapiens 36-43 25063149-7 2014 Contact angle measurements indicated that PEG grafted copolymers were more hydrophilic than parent copolymers. copolymers 54-64 progestagen associated endometrial protein Homo sapiens 42-45 25063149-7 2014 Contact angle measurements indicated that PEG grafted copolymers were more hydrophilic than parent copolymers. copolymers 99-109 progestagen associated endometrial protein Homo sapiens 42-45 24737104-6 2014 However, the copolymers with the aniline pentamer in the leucoemeraldine state had significantly lower CMCs than the copolymers with the aniline pentamer in the emeraldine state. copolymers 13-23 G protein signaling modulator 2 Homo sapiens 103-107 24945908-1 2014 A series of stimulus-responsive elastin-like polypeptide-poly(ethylene glycol) (ELP-PEG) block copolymers was synthesized. copolymers 95-105 nuclear receptor subfamily 5 group A member 1 Homo sapiens 80-83 24759871-2 2014 The hydrophobic content of the copolymers, P(MANa-co-DMA) and P(ANa-co-DAAm), is in the range of 0 to 25 mol%, while their weight-average molar mass varies from ~10 000 up to ~75 000. copolymers 31-41 mannosidase alpha class 2C member 1 Homo sapiens 45-49 28955022-5 2014 The block copolymers were functionalized with the dinitrophenyl (DNP) groups, which are capable of binding to Immunoglobulin E (IgE) on cell surfaces. copolymers 10-20 immunoglobulin heavy constant epsilon Homo sapiens 110-126 28955022-5 2014 The block copolymers were functionalized with the dinitrophenyl (DNP) groups, which are capable of binding to Immunoglobulin E (IgE) on cell surfaces. copolymers 10-20 immunoglobulin heavy constant epsilon Homo sapiens 128-131 24752806-0 2014 Label-free detection of C-reactive protein using highly dispersible gold nanoparticles synthesized by reducible biomimetic block copolymers. copolymers 129-139 C-reactive protein Homo sapiens 24-42 24651872-2 2014 Biodegradable block copolymers of poly(ethylene glycol) (PEG) and poly(epsilon-caprolactone) (PCL) were synthesized by ring opening copolymerization and characterized thoroughly using FTIR, (1)H NMR and GPC. copolymers 20-30 glycophorin C (Gerbich blood group) Homo sapiens 203-206 32261438-3 2014 Gene transfection efficiency of the copolymers (especially DAO) demonstrated improved performance compared to PEI25k in both HeLa and HEK 293 cell lines in the presence of serum. copolymers 36-46 D-amino acid oxidase Homo sapiens 59-62 24497034-2 2014 These highly asymmetric diblock DNA copolymers self-assemble into "hairy", star-like micelles, shown in the AFM image and the DPD snapshot. copolymers 36-46 dihydropyrimidine dehydrogenase Homo sapiens 126-129 24981025-4 2014 RESULTS: GGH copolymers could condense shRNA to form shRNA/GGH polyplex particles with a diameter in the range 122.8-331.6 nm in phosphate-buffered saline, and zeta potential values ranging from +3.7 to +16.5 mV at various charge ratios (N/P). copolymers 13-23 gamma-glutamyl hydrolase Homo sapiens 9-12 24981025-4 2014 RESULTS: GGH copolymers could condense shRNA to form shRNA/GGH polyplex particles with a diameter in the range 122.8-331.6 nm in phosphate-buffered saline, and zeta potential values ranging from +3.7 to +16.5 mV at various charge ratios (N/P). copolymers 13-23 gamma-glutamyl hydrolase Homo sapiens 59-62 24981025-5 2014 That the cytotoxicity of GGH copolymers was significantly lower than that of PEI in human hepatocellular liver carcinoma cells (HepG2) and human cervix epithelial carcinoma cells. copolymers 29-39 gamma-glutamyl hydrolase Homo sapiens 25-28 24981025-9 2014 CONCLUSIONS: GGH copolymers could integrate advantages relating to galactose content for hepatocyte targeting, guanidino groups for cell penetration and HPMA component for shielding, showing great potential for effective hepatocyte targeting gene delivery. copolymers 17-27 gamma-glutamyl hydrolase Homo sapiens 13-16 24696697-3 2014 EVIDENCE ACQUISITION: Recent reports have identified and explained the beneficial role of several structural molecules like mucoadhesive polymers (polyacrylic acid, sodium alginate, chitosan) and other copolymers for the efficient transport and release of insulin to its receptors. copolymers 202-212 insulin Homo sapiens 256-263 24332459-0 2014 Star-branched amphiphilic PLA-b-PDMAEMA copolymers for co-delivery of miR-21 inhibitor and doxorubicin to treat glioma. copolymers 40-50 microRNA 21 Homo sapiens 70-76 24239835-3 2014 Such membrane-modulating properties attributed to the unimer form of copolymers increase in the order Pluronic L61<<TBC<TBC-SA and correlate with an ability of TBCs to promote the accumulation of P-glycoprotein substrates in lung cancer A549 cells. copolymers 69-79 ATP binding cassette subfamily B member 1 Homo sapiens 205-219 25221630-6 2014 The TMA-functional copolymers were conjugated to the tumor targeting protein transferrin (Tf). copolymers 19-29 transferrin Homo sapiens 77-88 25221630-6 2014 The TMA-functional copolymers were conjugated to the tumor targeting protein transferrin (Tf). copolymers 19-29 transferrin Homo sapiens 90-92 24652240-0 2014 Lipase-catalyzed synthesis of azido-functionalized aliphatic polyesters towards acid-degradable amphiphilic graft copolymers. copolymers 114-124 PAN0_003d1715 Moesziomyces antarcticus 0-6 24417409-3 2014 The nature of the PD1 complex is described better in light of the affinity of DOX with the synthetic copolymers [poly(dA-dT)]2 and [poly(dG-dC)]2. copolymers 101-111 programmed cell death 1 Bos taurus 18-21 24261922-3 2014 NOSC in a wide concentration range even above the critical micelle concentration showed an effective effect on inhibiting P-gp-mediated PTX efflux, which was remarkably different from the surfactants and the Pluronic copolymers. copolymers 217-227 ATP binding cassette subfamily B member 1 Homo sapiens 122-126 24274731-6 2013 Deprotection of side-chain Boc- groups in the amphiphilic block copolymers subsequently transformed them into double hydrophilic pH-responsive cationic block copolymers having primary amino groups in the side-chain terminal. copolymers 64-74 BOC cell adhesion associated, oncogene regulated Homo sapiens 27-30 24038924-0 2014 In vitro evaluation of HPMA-copolymers targeted to HER2 expressing pancreatic tumor cells for image guided drug delivery. copolymers 28-38 erb-b2 receptor tyrosine kinase 2 Homo sapiens 51-55 32481979-8 2013 A series of pH titrations were also carried out, which quantified the shift of pH1/2 (pH when flactone = 0.5) after addition of the copolymers. copolymers 132-142 alanine--glyoxylate and serine--pyruvate aminotransferase Homo sapiens 79-84 24274731-6 2013 Deprotection of side-chain Boc- groups in the amphiphilic block copolymers subsequently transformed them into double hydrophilic pH-responsive cationic block copolymers having primary amino groups in the side-chain terminal. copolymers 158-168 BOC cell adhesion associated, oncogene regulated Homo sapiens 27-30 25619143-2 2013 We present a facile synthetic strategy for obtaining highly tunable thermo-responsive block copolymers starting from commercial PEG-based surfactants (Brij ) or a C18 precursor and conjugating with PNIPAAM via an Atom Transfer Radical Polymerization (ATRP) protocol. copolymers 92-102 Bardet-Biedl syndrome 9 Homo sapiens 163-166 24107101-2 2013 Herein, a series of comb-like amphiphilic copolymers bearing acetal-functionalized backbone were developed based on poly[(2,4,6-trimethoxybenzylidene-1,1,1-tris(hydroxymethyl) ethane methacrylate-co-poly(ethylene glycol) methyl ether methacrylate] [P(TTMA-co-mPEGMA)] as effective nanocarriers for intracellular curcumin (CUR) release. copolymers 42-52 transmembrane protein 200C Homo sapiens 251-255 23910324-4 2013 The evaluation of water uptakes and molecular weights during the degradation pointed out an early hydrolytic degradation of the 100-kg mol(-1) copolymers compared to the 200-kg mol(-1) ones (molecular weight decrease of ca. copolymers 143-153 modifier of LPS-response 1 Mus musculus 135-141 23910324-6 2013 A dramatic loss of tensile mechanical properties was also observed for the 100-kg mol(-1) copolymers, whereas the 200-kg mol(-1) copolymers showed stable or even slightly improved properties with Young"s moduli around 500 MPa and yield strains around 3% to 4%. copolymers 129-139 modifier of LPS-response 1 Mus musculus 121-127 23910324-7 2013 Finally, the cytocompatibility of the more stable 200 kg mol(-1) copolymers was confirmed by murine mesenchymal stem cells (MSCs) culture. copolymers 65-75 modifier of LPS-response 1 Mus musculus 57-63 23636840-3 2013 RESULTS: Only block copolymers with 2-hexanone and 2-octanone (PEG-HEX and PEG-OCT) formed micelles with a clinically relevant size (< 50 nm in diameter), low critical micelle concentration (CMC, < 20 muM), and drug entrapment yields (approximately 5 wt.%). copolymers 20-30 hematopoietically expressed homeobox Homo sapiens 67-70 24044647-3 2013 Then, three target hTERT siRNA TERT-1, TERT-2 and TERT-3 were designed and combined with GGA copolymers to form siRNA/GGA polyplexes. copolymers 93-103 telomerase reverse transcriptase Homo sapiens 19-24 24044647-3 2013 Then, three target hTERT siRNA TERT-1, TERT-2 and TERT-3 were designed and combined with GGA copolymers to form siRNA/GGA polyplexes. copolymers 93-103 telomerase reverse transcriptase Homo sapiens 20-24 23763603-8 2013 Moreover, some of the tested copolymers (e.g., BO12EO227BO12 and EO57PO46EO57 that notably increased and C16EO455C16 that decreased the P-gp ATPase activity) were observed to act as efficient inhibitors of the P-gp efflux pump promoting an enhanced doxorubicin (DOXO) accumulation inside multidrug resistant (MDR) NCI-ADR-RES cells. copolymers 29-39 phosphoglycolate phosphatase Homo sapiens 136-140 23763603-8 2013 Moreover, some of the tested copolymers (e.g., BO12EO227BO12 and EO57PO46EO57 that notably increased and C16EO455C16 that decreased the P-gp ATPase activity) were observed to act as efficient inhibitors of the P-gp efflux pump promoting an enhanced doxorubicin (DOXO) accumulation inside multidrug resistant (MDR) NCI-ADR-RES cells. copolymers 29-39 phosphoglycolate phosphatase Homo sapiens 210-214 23836721-3 2013 Remarkably, the resulting novel semiconducting graft copolymers with polyether side chains show different solubility and side-chain directed self-assembly behavior in various solvents, e.g., cylindrical or spherical superstructures in the size range of 10 to 120 nm, as shown by TEM. copolymers 53-63 MFT2 Homo sapiens 279-282 23636840-3 2013 RESULTS: Only block copolymers with 2-hexanone and 2-octanone (PEG-HEX and PEG-OCT) formed micelles with a clinically relevant size (< 50 nm in diameter), low critical micelle concentration (CMC, < 20 muM), and drug entrapment yields (approximately 5 wt.%). copolymers 20-30 latexin Homo sapiens 207-210 23548862-2 2013 The obtained copolymers were characterized by (1)H NMR, FT-IR, X-ray, and TGA/DTA. copolymers 13-23 T-box transcription factor 1 Homo sapiens 74-77 23740953-10 2013 We conclude that charge-dependent interactions of copolymers that alleviate MS/experimental autoimmune encephalomyelitis are critical for their effects exerted on APCs and may well be the main initial mediators of these therapeutically active copolymers. copolymers 50-60 amyloid P component, serum Mus musculus 163-167 23740953-10 2013 We conclude that charge-dependent interactions of copolymers that alleviate MS/experimental autoimmune encephalomyelitis are critical for their effects exerted on APCs and may well be the main initial mediators of these therapeutically active copolymers. copolymers 243-253 amyloid P component, serum Mus musculus 163-167 23337121-1 2013 Polyamidoamine-poly N,N"-di-(2-aminoethyl) aminoethyl glutamine graft copolymers (PAMAM-PAGA) were synthesized by polymerization of BLG-NCA and subsequent aminolysis with tris-(2-aminoethyl)-amine. copolymers 70-80 peroxiredoxin 1 Homo sapiens 82-92 23622691-7 2013 Subsequent to conjugation to the HPMA copolymer and radiolabeling with (177)Lu, the peptide-polymer conjugates were renamed (177)Lu-metabolically active copolymers ((177)Lu-MACs) with the corresponding designations: (177)Lu-MAC0, (177)Lu-MAC1 and (177)Lu-MAC2. copolymers 153-163 Ras and Rab interactor 2 Homo sapiens 173-177 23337121-1 2013 Polyamidoamine-poly N,N"-di-(2-aminoethyl) aminoethyl glutamine graft copolymers (PAMAM-PAGA) were synthesized by polymerization of BLG-NCA and subsequent aminolysis with tris-(2-aminoethyl)-amine. copolymers 70-80 CEA cell adhesion molecule 6 Homo sapiens 136-139 23374440-4 2013 The copolymers were characterized using FT-IR spectroscopy and TGA. copolymers 4-14 T-box transcription factor 1 Homo sapiens 63-66 23514516-0 2013 Segmented helical structures formed by ABC star copolymers in nanopores. copolymers 48-58 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 39-42 23365015-2 2013 The DTDPP-based copolymers P1 and P2 with an alternating donor-acceptor-donor-acceptor (D-A-D-A) sequence and the homopolymer P9 exhibit planarity and excellent pi-conjugation, which lead to low bandgaps (down to 1.22 eV) as well as strong and broad NIR absorption bands (up to 1000 nm). copolymers 16-26 crystallin gamma F, pseudogene Homo sapiens 27-36 23406541-1 2013 Nanostructured soft materials from self-assembled block copolymers (BCP)s and polymer blends can enable the reliable, high-throughput, and cost-effective generation of nanoscale structural motifs for many emerging technologies. copolymers 56-66 opsin 1, short wave sensitive Homo sapiens 68-71 23380628-11 2013 The inhibition of the P-gp efflux pump by some BOnEOmBOn copolymers, similar to that measured for the common P-gp inhibitor verapamil, favored the retention of DOXO inside the cell increasing its cytotoxic activity. copolymers 57-67 ATP binding cassette subfamily B member 1 Homo sapiens 22-26 23380628-11 2013 The inhibition of the P-gp efflux pump by some BOnEOmBOn copolymers, similar to that measured for the common P-gp inhibitor verapamil, favored the retention of DOXO inside the cell increasing its cytotoxic activity. copolymers 57-67 ATP binding cassette subfamily B member 1 Homo sapiens 109-113 23211870-0 2013 Synthesis, characterization, and self-assembly of linear poly(ethylene oxide)-block-poly(propylene oxide)-block-poly(epsilon-caprolactone) (PEO-PPO-PCL) copolymers. copolymers 153-163 protoporphyrinogen oxidase Homo sapiens 144-147 23214439-0 2013 Fibril formation by pH and temperature responsive silk-elastin block copolymers. copolymers 69-79 elastin Homo sapiens 55-62 32260753-10 2013 Therefore, LHRH-conjugated amphiphilic copolymers might be used as a potential drug delivery system for the treatment of LHRH receptor overexpressing carcinoma. copolymers 39-49 gonadotropin releasing hormone 1 Homo sapiens 11-15 23212920-6 2013 Copolymers of D11Q and wild type actins bound cofilin, but cofilin-induced depolymerization of the copolymers was slower than that of wild type filaments, which may presumably be the primary reason why this mutant actin is dominantly toxic in vivo. copolymers 0-10 cofilin 1 Homo sapiens 46-53 23212920-6 2013 Copolymers of D11Q and wild type actins bound cofilin, but cofilin-induced depolymerization of the copolymers was slower than that of wild type filaments, which may presumably be the primary reason why this mutant actin is dominantly toxic in vivo. copolymers 99-109 cofilin 1 Homo sapiens 59-66 23099248-1 2013 Amphiphilic block copolymers of the poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) family (commercially available as Pluronics or Poloxamers) are well-known for self-assembling in water (selective solvent for PEO) into micelles with a PPO-rich core and a hydrated PEO corona. copolymers 18-28 protoporphyrinogen oxidase Homo sapiens 84-87 23099248-1 2013 Amphiphilic block copolymers of the poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) family (commercially available as Pluronics or Poloxamers) are well-known for self-assembling in water (selective solvent for PEO) into micelles with a PPO-rich core and a hydrated PEO corona. copolymers 18-28 protoporphyrinogen oxidase Homo sapiens 241-244 23089310-0 2013 Mechanism of inhibition of P-glycoprotein mediated efflux by Pluronic P123/F127 block copolymers: relationship between copolymer concentration and inhibitory activity. copolymers 86-96 ATP binding cassette subfamily B member 1 Homo sapiens 27-41 23089310-1 2013 The aim of this study was to clarify the relationship between the concentration of Pluronic P123/F127 block copolymers and P-glycoprotein (P-gp) inhibitory potency. copolymers 108-118 ATP binding cassette subfamily B member 1 Homo sapiens 123-137 23089310-1 2013 The aim of this study was to clarify the relationship between the concentration of Pluronic P123/F127 block copolymers and P-glycoprotein (P-gp) inhibitory potency. copolymers 108-118 ATP binding cassette subfamily B member 1 Homo sapiens 139-143 23218268-3 2013 By controlling the cellulose:e-CL feed ratio and reaction temperature, the molecular architecture of the copolymers can be altered, as evidenced by FT-IR, (1)H NMR, (13)C NMR, TGA and XRD. copolymers 105-115 T-box transcription factor 1 Homo sapiens 176-179 23256509-1 2013 The phase behavior of two types of poly(ethylene oxide)/poly(propylene oxide) (PEO/PPO) copolymers in aqueous solutions was studied by light scattering, viscometry, and infrared spectroscopy. copolymers 88-98 protoporphyrinogen oxidase Homo sapiens 83-86 23470444-1 2013 Anhydride copolymers were synthesized from acrylic acid and fatty alcohols (C12- C18, C18:1). copolymers 10-20 Bardet-Biedl syndrome 9 Homo sapiens 81-84 23565868-6 2013 Copolymers containing C18 and C16 had the best inhibition effectiveness on both young biofilm and mature biofilm, copolymers containing C12 and C11 only had inhibition effectiveness on young biofilm and copolymer containing C10 had none inhibition effectiveness on neither young biofilm nor mature biofilm. copolymers 0-10 Bardet-Biedl syndrome 9 Homo sapiens 22-25 23565868-6 2013 Copolymers containing C18 and C16 had the best inhibition effectiveness on both young biofilm and mature biofilm, copolymers containing C12 and C11 only had inhibition effectiveness on young biofilm and copolymer containing C10 had none inhibition effectiveness on neither young biofilm nor mature biofilm. copolymers 114-124 RNA polymerase III subunit K Homo sapiens 144-147 23565868-6 2013 Copolymers containing C18 and C16 had the best inhibition effectiveness on both young biofilm and mature biofilm, copolymers containing C12 and C11 only had inhibition effectiveness on young biofilm and copolymer containing C10 had none inhibition effectiveness on neither young biofilm nor mature biofilm. copolymers 114-124 chromosome 12 open reading frame 57 Homo sapiens 224-227 23163230-0 2013 Conjugates of superoxide dismutase 1 with amphiphilic poly(2-oxazoline) block copolymers for enhanced brain delivery: synthesis, characterization and evaluation in vitro and in vivo. copolymers 78-88 superoxide dismutase 1, soluble Mus musculus 14-36 24324511-5 2013 Based on the elucidated binding motifs of Copaxone and of the anchor residues of the immunogenic myelin basic protein (MBP) peptide to HLA-DR molecules, novel copolymers have been designed and proved to be more effective in suppressing MS-like disease in mice. copolymers 159-169 myelin basic protein Mus musculus 97-117 24324511-5 2013 Based on the elucidated binding motifs of Copaxone and of the anchor residues of the immunogenic myelin basic protein (MBP) peptide to HLA-DR molecules, novel copolymers have been designed and proved to be more effective in suppressing MS-like disease in mice. copolymers 159-169 myelin basic protein Mus musculus 119-122 22968996-2 2013 After administration of these copolymers to mice, increases in several splenic myeloid cell populations were observed, including CD11b(+) CD11c(+) dendritic cells. copolymers 30-40 integrin subunit alpha M Homo sapiens 129-134 22968996-2 2013 After administration of these copolymers to mice, increases in several splenic myeloid cell populations were observed, including CD11b(+) CD11c(+) dendritic cells. copolymers 30-40 integrin subunit alpha X Homo sapiens 138-143 23470444-1 2013 Anhydride copolymers were synthesized from acrylic acid and fatty alcohols (C12- C18, C18:1). copolymers 10-20 Bardet-Biedl syndrome 9 Homo sapiens 86-89 23031592-4 2012 This work investigated for the first time the effect of branched poly(ethylene oxide)-poly(propylene oxide) block copolymers (poloxamines) on the levels of mRNA encoding for MDR1, BCRP and MRP1, in a human hepatoma cell line (Huh7). copolymers 114-124 ATP binding cassette subfamily B member 1 Homo sapiens 174-178 23140570-1 2012 Hybrid dendritic-linear block copolymers based on a 4-arm poly(ethylene glycol) (PEG) core were synthesized using an accelerated AB2/CD2 dendritic growth approach through orthogonal amine/epoxy and thiol-yne chemistries. copolymers 30-40 CD2 molecule Homo sapiens 133-136 23151204-2 2012 The segmented copolymers were obtained by the step growth polymerization of amino-terminated PEG and aliphatic diisocyanate. copolymers 14-24 progestagen associated endometrial protein Homo sapiens 93-96 23005031-0 2012 Unfolding of cytochrome C upon interaction with azobenzene-modified copolymers. copolymers 68-78 cytochrome c, somatic Homo sapiens 13-25 23005031-6 2012 These copolymers are, thus, capable to develop both ionic (under their sodium forms at pH > 8) and hydrophobic associations with the basic protein cyt c (isoelectric point of 10.0). copolymers 6-16 cytochrome c, somatic Homo sapiens 150-155 23031592-4 2012 This work investigated for the first time the effect of branched poly(ethylene oxide)-poly(propylene oxide) block copolymers (poloxamines) on the levels of mRNA encoding for MDR1, BCRP and MRP1, in a human hepatoma cell line (Huh7). copolymers 114-124 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 180-184 23031592-4 2012 This work investigated for the first time the effect of branched poly(ethylene oxide)-poly(propylene oxide) block copolymers (poloxamines) on the levels of mRNA encoding for MDR1, BCRP and MRP1, in a human hepatoma cell line (Huh7). copolymers 114-124 ATP binding cassette subfamily C member 1 Homo sapiens 189-193 22857013-7 2012 Binary systems consisting of simple (salen)Co(III)X and a nucleophilic cocatalyst exhibited high activity under mild conditions even at 0.1 MPa CO(2) pressure and afforded copolymers with >99% carbonate linkages and a high regiochemical control (~95% head-to-tail content). copolymers 172-182 mitochondrially encoded cytochrome c oxidase III Homo sapiens 46-49 22820448-2 2012 In contrast to other approaches, the copolymers demonstrated a clear separation between the hydrophilic PEG and the nucleic acid condensing PEI moieties. copolymers 37-47 progestagen associated endometrial protein Homo sapiens 104-107 22643837-7 2012 Copolymers of WT and increasing amounts of the mutant actins led to a reduced stimulation of the myosin ATPase. copolymers 0-10 myosin heavy chain 14 Homo sapiens 97-103 22891697-2 2012 Sequential ruthenium-mediated ring-opening metathesis polymerization of these macromonomers readily afforded well-defined brush block copolymers, with precisely tunable molecular weights ranging from high (1512 kDa) to ultrahigh (7119 kDa), while maintaining narrow molecular weight distributions (PDI = 1.08-1.39). copolymers 134-144 peptidyl arginine deiminase 1 Homo sapiens 298-305 22492502-1 2012 Copolymers of N-isopropylacrylamide (NIPAAm) and acrylic acid N-hydroxysuccinimide (NAS) were synthesized via free radical polymerization and conjugated with amine-functionalized hyaluronic acid (HA) and cell adhesive RGDS peptides. copolymers 0-10 ral guanine nucleotide dissociation stimulator Homo sapiens 218-222 22659093-1 2012 Three statistical poly(L-lactide-co-epsilon-caprolactone) (PLCL) copolymers of 70% L-lactide content having different chain microstructures ranging from moderate blocky to random (R=0.47,0.69 and 0.92, respectively) were characterized by DSC, GPC and (1)H and (13)C NMR. copolymers 65-75 phospholipase C like 1 (inactive) Homo sapiens 59-63 22575779-1 2012 The conformation and the dilatational properties of three non-ionic triblock PEO-PPO-PEO (where PEO is polyethyleneoxide and PPO is polypropyleneoxide) copolymers of different hydrophobicity and molecular weight were investigated at the water-hexane interface. copolymers 152-162 protoporphyrinogen oxidase Homo sapiens 81-84 22616905-2 2012 Using this property, we conjugated transferrin onto the surface of biodegradable polymeric micelles constructed from amphiphilic block copolymers. copolymers 135-145 transferrin Mus musculus 35-46 22533503-0 2012 Tuning the properties of elastin mimetic hybrid copolymers via a modular polymerization method. copolymers 48-58 elastin Homo sapiens 25-32 22392332-0 2012 Relationship between the affinity of PEO-PPO-PEO block copolymers for biological membranes and their cellular effects. copolymers 55-65 protoporphyrinogen oxidase Homo sapiens 41-44 22392332-1 2012 PURPOSE: The interactions of poly(ethylene oxide)-co-poly(propylene oxide) tri-block copolymers (PEO-PPO-PEO block copolymers, Pluronics , Synperonics , Poloxamers) of differing chemical composition with cell membranes were systematically investigated in order to clarify the mechanisms behind their previously reported various cellular responses. copolymers 85-95 protoporphyrinogen oxidase Homo sapiens 101-104 22533503-4 2012 The resultant hybrid copolymers contain an estimated five to seven repeats of PEG and AK2 peptides. copolymers 21-31 adenylate kinase 2 Homo sapiens 86-89 22434766-5 2012 More recently, ELP block copolymers have been developed that can assemble into micelles; however, it remains unclear if proteases can act on these ELP nanoparticles. copolymers 25-35 nuclear receptor subfamily 5 group A member 1 Homo sapiens 15-18 22273601-7 2012 Therefore, the LIOAS signals obtained with BSA, HSA, and tryptophan-containing random copolymers may be attributed to a new transition of the indole moiety of their tryptophan residues when "protonated". copolymers 86-96 albumin Homo sapiens 43-46 22574928-1 2012 Two donor-acceptor copolymers, P1 and P2, containing the novel donor component benzo[2,1-b:3,4-b":5,6-c""]trithiophene were synthesized. copolymers 19-29 crystallin gamma F, pseudogene Homo sapiens 31-40 22376183-4 2012 The structures of these copolymers were carefully characterized by (1)H NMR, FT-IR, and GPC. copolymers 24-34 glycophorin C (Gerbich blood group) Homo sapiens 77-91 22498288-3 2012 The overall conversion of these PLCL copolymers was in the range of 80%-90% leading to weight average molecular weights (M(w)) between 98,500 and 226,000 g mol(-1) depending on feed composition and polymerization temperature. copolymers 37-47 phospholipase C like 1 (inactive) Homo sapiens 32-36 22519413-4 2012 The PNBC-b-PEO copolymers self-assembled into spherical nanoparticles in aqueous solution, presenting a photoresponsive self-assembly behavior, together with a size reduction of nanoparticles after irradiation. copolymers 15-25 twinkle mtDNA helicase Homo sapiens 11-14 22530612-4 2012 TGA and DSC thermal analysis have indicated that the copolymers were thermally stable under regular pulping conditions, revealing the inertness of the styrene polymer backbone in the investigation of electron transfer mechanisms. copolymers 53-63 T-box transcription factor 1 Homo sapiens 0-3 22415360-0 2012 Synthesis of amphiphilic [PEO(PCL)2] triarm star-shaped block copolymers: a promising system for in cell delivery. copolymers 62-72 metal response element binding transcription factor 2 Homo sapiens 30-35 22354326-10 2012 These observations suggested that the PLGA-PEG block copolymers nanomicelles have been prepared by a new synthetic route are potent nanocarrier for poorly water-soluble drugs as insulin. copolymers 53-63 insulin Homo sapiens 178-185 22415360-1 2012 The paper reports on a simple method of synthesizing [PEO(PCL)(2)] triarm star-shaped copolymers by a combination of Michael-addition type reaction and ring-opening polymerization. copolymers 86-96 PHD finger protein 1 Homo sapiens 58-61 22428724-5 2012 Among the several block copolymers, the one consisting of poly(2-ethylhexyl methacrylate) and polyperoxide from methyl sorbate (PPMS) (M(n) = 4900) exhibited good performance as a pressure-sensitive adhesive (PSA). copolymers 24-34 aminopeptidase puromycin sensitive Homo sapiens 209-212 22322211-3 2012 We report here the preparation of targeted nanoparticles from original amphiphilic block copolymers functionalized with an analog of sialyl Lewis X (SLEx), the physiological ligand of E-selectin. copolymers 89-99 selectin E Homo sapiens 184-194 22278846-1 2012 The conformational changes of fibronectin (FN) deposited on various block copolymers where one block is composed of poly(methyl methacrylate) (PMMA) and the other block is either poly(acrylic acid) (PAA) or poly(2-hydroxyethyl methacrylate) (PHEMA) were investigated using a functionalized atomic force microscope (AFM) tip. copolymers 74-84 fibronectin 1 Homo sapiens 30-41 22278846-1 2012 The conformational changes of fibronectin (FN) deposited on various block copolymers where one block is composed of poly(methyl methacrylate) (PMMA) and the other block is either poly(acrylic acid) (PAA) or poly(2-hydroxyethyl methacrylate) (PHEMA) were investigated using a functionalized atomic force microscope (AFM) tip. copolymers 74-84 fibronectin 1 Homo sapiens 43-45 22292618-4 2012 The system is composed of superoxide dismutase (SOD) conjugated to oxidation-sensitive amphiphilic polysulfide/PEG block copolymers; the conjugate combines the SOD reactivity toward superoxide with that of hydrophobic thioethers toward hydrogen peroxide. copolymers 121-131 superoxide dismutase 1 Homo sapiens 26-46 22292618-4 2012 The system is composed of superoxide dismutase (SOD) conjugated to oxidation-sensitive amphiphilic polysulfide/PEG block copolymers; the conjugate combines the SOD reactivity toward superoxide with that of hydrophobic thioethers toward hydrogen peroxide. copolymers 121-131 superoxide dismutase 1 Homo sapiens 48-51 22292618-4 2012 The system is composed of superoxide dismutase (SOD) conjugated to oxidation-sensitive amphiphilic polysulfide/PEG block copolymers; the conjugate combines the SOD reactivity toward superoxide with that of hydrophobic thioethers toward hydrogen peroxide. copolymers 121-131 superoxide dismutase 1 Homo sapiens 160-163 22189143-2 2012 The aim of this study was to develop a G3-C12-mediated drug delivery system based on N-(2-hydroxypropyl) methacrylamide (HPMA) copolymers targeting to Gal-3-expressed human PC-3 prostate carcinoma cells. copolymers 127-137 galectin 3 Homo sapiens 151-156 22169826-4 2012 The resultant diblock copolymers exhibited low polydispersity (PDI <= 1.06) with similar molecular weights (M(n) = 19.3-23.1 kDa). copolymers 22-32 peptidyl arginine deiminase 1 Homo sapiens 63-66 22192075-3 2012 We have studied the properties of HCHT by analyzing how the enzyme acts on high-molecular weight chitosans, soluble copolymers of beta-1,4-linked N-acetylglucosamine (GlcNAc, A), and glucosamine (GlcN, D). copolymers 116-126 solute carrier family 5 member 7 Homo sapiens 34-38 22036879-5 2012 Cathepsin B degraded copolymers pHCathK(10) and pHCath(D)K(10) within 1 h while no degradation of pH(D)Cath(D)K(10) was observed. copolymers 21-31 cathepsin B Homo sapiens 0-11 22036879-6 2012 Polyplexes formed with pHCathK(10) copolymers show DNA release by 4 h of treatment with cathepsin B; comparatively, polyplexes formed with pHCath(D)K(10) and pH(D)Cath(D)K(10) show no DNA release within 8 h. Transfection efficiency in HeLa and NIH/3T3 cells were comparable between the copolymers but pHCathK(10) was less toxic. copolymers 35-45 cathepsin B Homo sapiens 88-99 21703990-1 2012 UNLABELLED: Formulations of antioxidant enzymes, superoxide dismutase 1 (SOD1, also known as Cu/Zn SOD) and catalase were prepared by electrostatic coupling of enzymes with cationic block copolymers, polyethyleneimine-poly(ethylene glycol) or poly(L-lysine)-poly(ethylene glycol), followed by covalent cross-linking to stabilize nanoparticles (NPs). copolymers 188-198 superoxide dismutase 1, soluble Mus musculus 49-71 22100241-3 2012 Furthermore, effects of initial pH, ionic strength, temperature, contact time and initial metal ion concentration on the biosorption capacities of Cu(II) and Co(II) ions onto the copolymers were studied using batch sorption technique. copolymers 179-189 mitochondrially encoded cytochrome c oxidase II Homo sapiens 158-164 22100241-4 2012 It was found that the copolymers exhibited excellent biosorption characteristics for Cu(II) and Co(II) ions. copolymers 22-32 mitochondrially encoded cytochrome c oxidase II Homo sapiens 96-102 23028218-1 2012 A series of biodegradable thermosensitive copolymers was synthesized by free radical polymerization with N-isopropylacrylamide (NIPAAm), acrylic acid (AAc) and macromer 2-hydroxylethyl methacrylate-poly(e-caprolactone) (HEMAPCL). copolymers 42-52 glycine-N-acyltransferase Homo sapiens 151-154 21703990-1 2012 UNLABELLED: Formulations of antioxidant enzymes, superoxide dismutase 1 (SOD1, also known as Cu/Zn SOD) and catalase were prepared by electrostatic coupling of enzymes with cationic block copolymers, polyethyleneimine-poly(ethylene glycol) or poly(L-lysine)-poly(ethylene glycol), followed by covalent cross-linking to stabilize nanoparticles (NPs). copolymers 188-198 superoxide dismutase 1, soluble Mus musculus 73-77 21703990-1 2012 UNLABELLED: Formulations of antioxidant enzymes, superoxide dismutase 1 (SOD1, also known as Cu/Zn SOD) and catalase were prepared by electrostatic coupling of enzymes with cationic block copolymers, polyethyleneimine-poly(ethylene glycol) or poly(L-lysine)-poly(ethylene glycol), followed by covalent cross-linking to stabilize nanoparticles (NPs). copolymers 188-198 superoxide dismutase 1, soluble Mus musculus 93-102 21703990-1 2012 UNLABELLED: Formulations of antioxidant enzymes, superoxide dismutase 1 (SOD1, also known as Cu/Zn SOD) and catalase were prepared by electrostatic coupling of enzymes with cationic block copolymers, polyethyleneimine-poly(ethylene glycol) or poly(L-lysine)-poly(ethylene glycol), followed by covalent cross-linking to stabilize nanoparticles (NPs). copolymers 188-198 catalase Mus musculus 108-116 22047492-0 2011 Nanocapsules based on linear and Y-shaped 3-miktoarm star-block PEO-PCL copolymers as sustained delivery system for hydrophilic molecules. copolymers 72-82 PHD finger protein 1 Homo sapiens 68-71 22047492-1 2011 Well-defined amphiphilic Y-shaped miktoarm star-block copolymers of PEO and PCL were synthesized by ring-opening polymerization of epsilon-caprolactone initiated by a PEO-bound lysine macroinitiator. copolymers 54-64 PHD finger protein 1 Homo sapiens 76-79 22047492-3 2011 Separate PCL and PEO crystalline phases occur in melt-crystallized copolymers when their segmental lengths were comparable and the PCL content was <=80 wt %. copolymers 67-77 PHD finger protein 1 Homo sapiens 9-12 22074249-3 2011 The targetability of the G3-C12 bearing copolymers towards galectin-3 was further compared to that of galactose-containing copolymers. copolymers 40-50 galectin 3 Homo sapiens 59-69 21763734-4 2011 To this end we utilized amphiphilic block copolymers, composed of a genetically engineered elastin-like polypeptide (ELP) that self-assemble into monodisperse spherical micelles. copolymers 42-52 nuclear receptor subfamily 5 group A member 1 Homo sapiens 91-115 21855892-0 2011 Effect of pH on the single-step synthesis of gold nanoparticles using PEO-PPO-PEO triblock copolymers in aqueous media. copolymers 91-101 protoporphyrinogen oxidase Homo sapiens 74-77 21763734-4 2011 To this end we utilized amphiphilic block copolymers, composed of a genetically engineered elastin-like polypeptide (ELP) that self-assemble into monodisperse spherical micelles. copolymers 42-52 nuclear receptor subfamily 5 group A member 1 Homo sapiens 117-120 21938302-3 2011 The obtained copolymers were characterized by (1)H NMR, GPC and TGA. copolymers 13-23 glycophorin C (Gerbich blood group) Homo sapiens 56-59 21931897-1 2011 Multi-armed biodegradable block copolymers with a bioreducible core mPCL-b-PEO were for the first time synthesized by thiol-yne click chemistry. copolymers 32-42 polycystic kidney disease 2-like 1 Mus musculus 68-72 21869956-0 2011 Synthesis of hybrid block copolymers via integrated ring-opening metathesis polymerization and polymerization of NCA. copolymers 26-36 CEA cell adhesion molecule 6 Homo sapiens 113-116 21938302-3 2011 The obtained copolymers were characterized by (1)H NMR, GPC and TGA. copolymers 13-23 T-box transcription factor 1 Homo sapiens 64-67 21769333-1 2011 Mid-functionalized ABC triblock copolymers with a short central B block were synthesized via the RAFT process, and further used as well-defined V-shaped copolymers to graft onto graphene oxide by coupling reactions. copolymers 32-42 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 19-22 21563804-1 2011 A series of poly(propylene oxide)-b-poly(L-lysine) (PPO-PK) block copolymers were synthesized using Huisgen"s 1,3-dipolar cycloaddition, and the solution self-assembly was studied using transmission electron microscopy, circular dichroism spectroscopy, and dynamic and static light scattering techniques. copolymers 66-76 protoporphyrinogen oxidase Homo sapiens 52-55 21612291-1 2011 The Horner method was used to synthesize random copolymers of poly(2-methoxy-5-(2"-ethylhexyloxy)-p-phenylene vinylene) (MEH-PPV) that incorporated different backbone-directing monomers. copolymers 48-58 epoxide hydrolase 1 Homo sapiens 121-124 21549166-1 2011 A library of mono-methoxyl-poly(ethylene glycol)-block-poly(epsilon-caprolactone) (mPEG-PCL) modified hyperbranched PEI copolymers (hy-PEI-PCL-mPEG) was synthesized to establish structure function relationships for siRNA delivery. copolymers 120-130 PHD finger protein 1 Homo sapiens 88-91 21549166-1 2011 A library of mono-methoxyl-poly(ethylene glycol)-block-poly(epsilon-caprolactone) (mPEG-PCL) modified hyperbranched PEI copolymers (hy-PEI-PCL-mPEG) was synthesized to establish structure function relationships for siRNA delivery. copolymers 120-130 PHD finger protein 1 Homo sapiens 139-142 21621596-8 2011 According to our outcomes, regular drug release process may be obtained from highly randomized copolymers (R 1) that remain amorphous during degradation process. copolymers 95-105 CD1b molecule Homo sapiens 107-112 21707082-0 2011 High-order multiblock copolymers via iterative Cu(0)-mediated radical polymerizations (SET-LRP): toward biological precision. copolymers 22-32 LDL receptor related protein 1 Homo sapiens 91-94 21438062-3 2011 This original combination of "clip" and "click" reactions provides a versatile and straightforward pathway for the synthesis of functional amphiphilic and degradable copolymers valuable for biomedical applications such as in drug-delivery. copolymers 166-176 CAP-Gly domain containing linker protein 1 Homo sapiens 30-35 21268025-1 2011 To develop self-regulated insulin delivery system, the glucose-sensitive copolymers with a fraction of phenylboronic acid group were prepared by the coupling reaction of -COOH of N-(carboxyacyl) chitosan and -NH(2) of 3-aminophenylboronic acid. copolymers 73-83 insulin Homo sapiens 26-33 21506527-5 2011 The third method consists of using copolymers comprising glycidyl methacrylate and propargyl methacrylate (pGP). copolymers 35-45 phosphoglycolate phosphatase Homo sapiens 107-110 21469235-0 2011 Self-assembly of monodisperse oligonucleotide-elastin block copolymers into stars and compound micelles. copolymers 60-70 elastin Homo sapiens 46-53 21401021-5 2011 The characteristics of the copolymers in their protected and deprotected forms were characterized by (1)H NMR, (13)C NMR, GPC, TGA, and DSC. copolymers 27-37 glycophorin C (Gerbich blood group) Homo sapiens 122-125 21401021-5 2011 The characteristics of the copolymers in their protected and deprotected forms were characterized by (1)H NMR, (13)C NMR, GPC, TGA, and DSC. copolymers 27-37 T-box transcription factor 1 Homo sapiens 127-130 21218764-5 2011 It was found that Cs-g-MCPA copolymers with different grafted positions showed different properties: copolymers grafted on the C-2 position showed higher cytotoxicity and higher transfection efficiency than those grafted on position C-6. copolymers 28-38 complement C2 Homo sapiens 127-130 21246150-5 2011 Based on the established wrapping strategy, we have further extended the wrapping techniques toward the creation of three-dimensional polymeric architectures, in which the polymer/beta-1,3-glucan composite behaves as a sort of amphiphilic block copolymers. copolymers 245-255 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 Homo sapiens 180-188 21123038-0 2011 Micelles from PEO-PPO-PEO block copolymers as nanocontainers for solubilization of a poorly water soluble drug hydrochlorothiazide. copolymers 32-42 protoporphyrinogen oxidase Homo sapiens 18-21 21449317-1 2011 In this work, fluorescently labeled smart micelle copolymers which consist of Dioctadecylamine-501 (DODA-501) as the hydrophobic segment, N-isopropylacrylamide (NIPAAm) as well as acrylic acid (AAc) as the hydrophilic segments were prepared. copolymers 50-60 glycine-N-acyltransferase Homo sapiens 194-197 21326142-3 2011 The obtained copolymers were characterized by DSC, GPC and 13C-NMR. copolymers 13-23 glycophorin C (Gerbich blood group) Homo sapiens 51-54 21218764-5 2011 It was found that Cs-g-MCPA copolymers with different grafted positions showed different properties: copolymers grafted on the C-2 position showed higher cytotoxicity and higher transfection efficiency than those grafted on position C-6. copolymers 28-38 complement C6 Homo sapiens 233-236 21166396-3 2011 Kinetic analyses confirm high conversions of up to 99.98% and a living behavior of the SET-LRP process providing high molecular weight hemicelluloses/methyl acrylate hybrid copolymers with a brush-like architecture. copolymers 173-183 LDL receptor related protein 1 Homo sapiens 91-94 21992560-0 2011 Role of Pluronic block copolymers in modulation of heat shock protein 70 expression. copolymers 23-33 heat shock protein family A (Hsp70) member 1B Rattus norvegicus 51-72 23678418-6 2011 Copolymers were loaded with regular insulin by modified double emulsion method with ratio of 1:10. copolymers 0-10 insulin Homo sapiens 36-43 21093476-4 2011 Fluorescence spectrum of HEC-g-PCL copolymer dilute solution indicated that copolymers could associate and form hydrophobic microdomains in aqueous solution. copolymers 76-86 PHD finger protein 1 Homo sapiens 31-34 20441783-2 2010 In particular, recombinant elastin block copolymers provide significant opportunities to modulate material microstructure and can be processed in various forms, including particles, films, gels, and fiber networks. copolymers 41-51 elastin Homo sapiens 27-34 21674323-2 2011 As a demonstration of this approach, poly(acrylic acid) (PAA)-based near-infrared fluorescence (NIRF) dye- and glucose-incorporated novel copolymers were synthesized, which were further employed for bioconjugation to avidin and bovine serum albumin (BSA). copolymers 138-148 albumin Homo sapiens 235-248 22194778-2 2011 A major mechanism through which copolymers function to ameliorate disease is the generation of immunosuppressive IL-10-secreting regulatory T cells entering the CNS. copolymers 32-42 interleukin 10 Mus musculus 113-118 21128720-8 2010 CONCLUSION: The anti-P-gp activity is maxima for block copolymers possessing a low-to-medium hydrophilic-lipophilic balance and an "effective number" of PO units ranging from 30 to 50. copolymers 55-65 ATP binding cassette subfamily B member 1 Homo sapiens 21-25 20696244-5 2010 RAFT polymerisation facilitated the synthesis of semitelechelic copolymers, which were used in the synthesis of monoclonal anti-CD20 antibody-polymer-drug conjugate designed for cell-specific tumour targeting. copolymers 64-74 keratin 20 Homo sapiens 128-132 21082844-0 2010 Monte Carlo simulation of self-assembly of symmetric ABC three-arm star copolymers under cylindrical confinement. copolymers 72-82 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 53-56 21082844-3 2010 For the symmetric ABC three-arm star copolymers which form polygonal cylinder structures with periodic spacing L(0) in bulk, various novel structures are observed inside the nanopores. copolymers 37-47 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 18-21 21139997-0 2010 Cationic nano-copolymers mediated IKKbeta targeting siRNA to modulate wound healing in a monkey model of glaucoma filtration surgery. copolymers 14-24 inhibitor of nuclear factor kappa B kinase subunit beta Homo sapiens 34-41 21139997-1 2010 PURPOSE: To investigate the efficacy and safety of cationic nano-copolymers CS-g-(PEI-b-mPEG) mediated IkappaB kinase beta (IKKbeta) targeting siRNA in modulating wound healing in a monkey model of glaucoma filtration surgery. copolymers 65-75 inhibitor of nuclear factor kappa B kinase subunit beta Homo sapiens 103-122 21139997-1 2010 PURPOSE: To investigate the efficacy and safety of cationic nano-copolymers CS-g-(PEI-b-mPEG) mediated IkappaB kinase beta (IKKbeta) targeting siRNA in modulating wound healing in a monkey model of glaucoma filtration surgery. copolymers 65-75 inhibitor of nuclear factor kappa B kinase subunit beta Homo sapiens 124-131 21139997-13 2010 CONCLUSIONS: Subconjunctival injection of cationic nano-copolymers mediated IKKbeta targeting siRNA is associated with improved surgical outcome in a monkey model of trabeculectomy. copolymers 56-66 inhibitor of nuclear factor kappa B kinase subunit beta Homo sapiens 76-83 21399721-5 2010 Assembly of PEO-b-PIp block copolymers in aqueous solution resulted in well-defined micelles of varying sizes while the assembly in hydrophobic, organic solvent resulted in the formation of different morphologies including large aggregates and well-defined cylindrical and spherical structures. copolymers 28-38 prolactin induced protein Homo sapiens 18-21 21567599-4 2010 It has been found that the surfaces of the block copolymers simultaneously exhibit excellent anti-fog and oil-repellent properties. copolymers 49-59 zinc finger protein, FOG family member 1 Homo sapiens 98-101 20363305-5 2010 By modulating the concentrations of micelle-forming copolymers, the burst release of 17-AAG from PEG-DSPE/TPGS mixed micelles was substantially reduced with a release half-life up to about 8h. copolymers 52-62 N-methylpurine DNA glycosylase Homo sapiens 88-91 20703381-5 2010 With this strategy it is possible to combine high molecular weight with good molecular weight control (up to 16,000 g/mol, PDI = 1.4-1.7), resulting in PGA multi-arm star block copolymers containing more than 90 wt % GA. copolymers 177-187 peptidyl arginine deiminase 1 Homo sapiens 123-130 20481635-3 2010 Here we present an alternative approach to SP-B mimicry that is based on sequence-random copolymers containing cationic and lipophilic subunits. copolymers 89-99 surfactant protein B Homo sapiens 43-47 20596457-4 2010 The obtained random copolymers were characterized by 1H NMR, FTIR, GPC and TGA. copolymers 20-30 glycophorin C (Gerbich blood group) Homo sapiens 67-70 20167328-2 2010 For identical PEO/PPO ratios, copolymers with lower molecular weight show a larger increase in the cloud point in the presence of surfactants than polymers with higher molecular weight. copolymers 30-40 protoporphyrinogen oxidase Homo sapiens 18-21 20217189-4 2010 All the as-prepared copolymers were characterized by 1H NMR, FT-IR and GPC. copolymers 20-30 glycophorin C (Gerbich blood group) Homo sapiens 61-74 20596457-4 2010 The obtained random copolymers were characterized by 1H NMR, FTIR, GPC and TGA. copolymers 20-30 T-box transcription factor 1 Homo sapiens 75-78 20005933-4 2010 Four PBLG derivates were successfully obtained by ring-opening polymerization (ROP) of NCA, using various initiators corresponding to the molecules to be introduced into the copolymers. copolymers 174-184 CEA cell adhesion molecule 6 Homo sapiens 87-90 20975670-4 2010 Unprecedented ABCC-sequence-regulated copolymers with perfect vinyl chloride-styrene-acrylate-acrylate sequences were obtained by copper-catalysed step-growth radical polymerization of designed monomers possessing unconjugated C=C and reactive C-Cl bonds. copolymers 38-48 ATP binding cassette subfamily C member 1 Homo sapiens 14-18 20047821-2 2010 In particular, cationic chitosan-graft-polycaprolactone (CS-g-PCL) copolymers were synthesized with a facile one-pot manner via ring-opening polymerization of epsilon-CL onto the hydroxyl groups of CS by using methanesulfonic acid as solvent and catalyst. copolymers 67-77 polycystic kidney disease 2-like 1 Mus musculus 62-65 20184309-7 2010 PRe-RDL can also be used to assemble genes that encode different sequences in a predetermined order to encode block copolymers or append leader and trailer peptide sequences to the oligomerized gene. copolymers 116-126 LEO1 homolog, Paf1/RNA polymerase II complex component Homo sapiens 4-7 20095618-6 2010 In addition to the bulk-phase transformation, the rigid-rod characteristic of the conducting PPH block also affects the self-assembling property of the block copolymers in their solution state. copolymers 158-168 enolase 1 Homo sapiens 93-96 19470397-1 2009 Silk-elastinlike protein polymers (SELP"s) are block copolymers of silk-like and elastin-like tandem repeats. copolymers 53-63 selectin P Homo sapiens 35-39 20151706-7 2010 In (EO)(m)(PO)(n)(EO)(m) block copolymers, this process is complicated by the stripping of PEO chains of a part of hydrogen-bound water and entwining them with PPO. copolymers 31-41 protoporphyrinogen oxidase Homo sapiens 160-163 20217174-3 2010 The derivative technique also revealed for the first time a substantial increase in glassy-state expansivity with increasing nBMA content in S/nBMA random copolymers, from 1.4x10(-4) K-1 in PS to 3.5x10(-4) K-1 in PnBMA. copolymers 155-165 keratin 1 Homo sapiens 183-186 21590919-3 2010 DSC and TGA results indicate that these copolymers possess good thermal stabilities. copolymers 40-50 desmocollin 3 Homo sapiens 0-3 21590919-3 2010 DSC and TGA results indicate that these copolymers possess good thermal stabilities. copolymers 40-50 T-box transcription factor 1 Homo sapiens 8-11 19470397-1 2009 Silk-elastinlike protein polymers (SELP"s) are block copolymers of silk-like and elastin-like tandem repeats. copolymers 53-63 elastin Homo sapiens 5-12 19670196-8 2009 Its backbone can formally be derived by 1-olefin polymerization of CPE (1,3-insertion) followed by five ethylene units and thus serves as an excellent model compound for 1-olefin polymerization-derived copolymers. copolymers 202-212 carboxypeptidase E Homo sapiens 67-70 19716600-3 2009 The targeted copolymers displaying multiple copies of Esbp are bound to surface-associated E-selectin with affinity at the low nano-molar range, three orders of magnitude stronger than the free Esbp. copolymers 13-23 selectin E Homo sapiens 91-101 19716600-4 2009 In addition, the binding affinity of the HPMA-Esbp copolymers to E-selectin expressing IVECs was found to be 10-fold superior relative to non-targeted copolymers. copolymers 51-61 selectin E Homo sapiens 65-75 19716600-5 2009 Once bound, E-selectin facilitated rapid internalization and lysosomal trafficking of the copolymers. copolymers 90-100 selectin E Homo sapiens 12-22 19545594-6 2009 In cell and mouse experiments, higher gene expression was observed in complexes of pDNA with copolymers pended PKC alpha-specific substrate peptide than that in complexes with negative copolymers pended peptide substituted phosphorylation site of serine residues with alanine. copolymers 93-103 protein kinase C, alpha Mus musculus 111-120 19402140-2 2009 To enhance the adhesion of cells and to induce their differentiation into osteoblasts poly-L-lysine and BMP-2 were coupled to polymers and copolymers based on 2-deoxy-N-methacrylamido-D-glucose (ox.p(MAG) and p(MVA)) used as spacer, which were adsorbed onto the ceramic surface. copolymers 139-149 bone morphogenetic protein 2 Homo sapiens 104-109 19068472-4 2009 In this study, we developed copolymers (PPy-NSE) of N-hydroxyl succinimidyl ester pyrrole and regular pyrrole, which can be immobilized with nerve growth factor (NGF) without significantly hindering electroconductivity. copolymers 28-38 enolase 2 Rattus norvegicus 44-47 19068472-4 2009 In this study, we developed copolymers (PPy-NSE) of N-hydroxyl succinimidyl ester pyrrole and regular pyrrole, which can be immobilized with nerve growth factor (NGF) without significantly hindering electroconductivity. copolymers 28-38 nerve growth factor Rattus norvegicus 141-160 19068472-4 2009 In this study, we developed copolymers (PPy-NSE) of N-hydroxyl succinimidyl ester pyrrole and regular pyrrole, which can be immobilized with nerve growth factor (NGF) without significantly hindering electroconductivity. copolymers 28-38 nerve growth factor Rattus norvegicus 162-165 19504187-10 2009 The largest (37 kDa) copolymer HC-6-8 demonstrated highest transfection levels among all the bioreducible copolymers, which was comparable with LPEI and much more effective than BPEI. copolymers 106-116 heterochromatin, Chr 6 Mus musculus 31-37 19588920-3 2009 A one-pot sequential amidation of the PAA with the amine derivatives of a near-infrared fluorescent dye (ADS832WS) and glucose produced NIRF dye-incorporated water-soluble copolymers. copolymers 172-182 interleukin 17B Homo sapiens 136-140 19705882-1 2009 Biodegradable copolymers consisting of a hydrophilic poly[l-aspartic acid-alt-poly(ethylene glycol)] (poly(l-Asp-alt-PEG)) backbone and hydrophobic capryl units as side chains were synthesized. copolymers 14-24 progestagen associated endometrial protein Homo sapiens 117-120 19417740-3 2009 Because antigen expression is weak after naked DNA injection, we screened five nonionic block copolymers of poly(ethyleneoxide)-poly(propyleneoxide) (PEO-PPO) for their ability to enhance DNA vaccination using a beta-galactosidase (betaGal) encoding plasmid, pCMV-betaGal, as immunogen. copolymers 94-104 protoporphyrinogen oxidase Mus musculus 154-157 19422014-1 2009 The influence of the surface fraction of OH groups on fibrinogen (FG) adsorption is investigated in copolymers of ethyl acrylate and hydroxy ethylacrylate. copolymers 100-110 fibrinogen beta chain Homo sapiens 54-64 19422014-1 2009 The influence of the surface fraction of OH groups on fibrinogen (FG) adsorption is investigated in copolymers of ethyl acrylate and hydroxy ethylacrylate. copolymers 100-110 fibrinogen beta chain Homo sapiens 66-68 19417740-3 2009 Because antigen expression is weak after naked DNA injection, we screened five nonionic block copolymers of poly(ethyleneoxide)-poly(propyleneoxide) (PEO-PPO) for their ability to enhance DNA vaccination using a beta-galactosidase (betaGal) encoding plasmid, pCMV-betaGal, as immunogen. copolymers 94-104 galactosidase, beta 1 Mus musculus 212-230 19417740-3 2009 Because antigen expression is weak after naked DNA injection, we screened five nonionic block copolymers of poly(ethyleneoxide)-poly(propyleneoxide) (PEO-PPO) for their ability to enhance DNA vaccination using a beta-galactosidase (betaGal) encoding plasmid, pCMV-betaGal, as immunogen. copolymers 94-104 galactosidase, beta 1 Mus musculus 232-239 19417740-3 2009 Because antigen expression is weak after naked DNA injection, we screened five nonionic block copolymers of poly(ethyleneoxide)-poly(propyleneoxide) (PEO-PPO) for their ability to enhance DNA vaccination using a beta-galactosidase (betaGal) encoding plasmid, pCMV-betaGal, as immunogen. copolymers 94-104 galactosidase, beta 1 Mus musculus 264-271 19417740-4 2009 At a high DNA dose, formulation with the tetrafunctional block copolymers 304 (molecular weight [MW] 1,650) and 704 (MW 5,500) and the triblock copolymer Lutrol (MW 8,600) increased betaGal-specific interferon-gamma enzyme-linked immunosorbent spot (ELISPOT) responses 2-2.5-fold. copolymers 63-73 galactosidase, beta 1 Mus musculus 182-189 19331320-9 2009 Here we also report solution-processed ambipolar films of thiophene-based molecule 12 and copolymers P13 and P14 which exhibit electron and hole mobilities of 1 x 10(-3)-2 x 10(-4) and I(on)/I(off) ratios of approximately 10(4), representing the first examples of molecular and polymeric ambipolar semiconductors to function in air. copolymers 90-100 H3 histone pseudogene 6 Homo sapiens 101-104 19132500-1 2009 A new type of biodegradable amphiphilic graft copolymers, PEG-g-hexanoyl chitosan, was synthesized by a facile scheme. copolymers 46-56 progestagen associated endometrial protein Homo sapiens 58-61 19132500-4 2009 With the increase of PEG content in the copolymers, the average diameter of the nanoparticles decreased from about 180 to 40 nm. copolymers 40-50 progestagen associated endometrial protein Homo sapiens 21-24 19132500-5 2009 PEG fraction in the copolymers has little effect on the copolymer CAC. copolymers 20-30 progestagen associated endometrial protein Homo sapiens 0-3 19225872-3 2009 Drug release from copolymers was evaluated using cathepsin B. copolymers 18-28 cathepsin B Mus musculus 49-60 19344119-4 2009 It indicated that conjugation of anti-PSMA to HPMA copolymers did not compromise their binding affinity. copolymers 51-61 folate hydrolase 1 Homo sapiens 38-42 19580769-3 2009 To test this hypothesis, a set of linear and di- and triblock ELP copolymers were designed and produced as recombinant proteins. copolymers 66-76 nuclear receptor subfamily 5 group A member 1 Homo sapiens 62-65 19476331-0 2009 Integrin alphaVbeta3 targeted gene delivery using RGD peptidomimetic conjugates with copolymers of PEGylated poly(ethylene imine). copolymers 85-95 integrin subunit alpha V Homo sapiens 0-20 19323556-5 2009 To the best of our knowledge, this is the first report that describes the synthesis of dendron-like polypeptide/linear PCL block copolymers with asymmetrical topology via the combination of ROP and click chemistry. copolymers 129-139 PHD finger protein 1 Homo sapiens 119-122 19331320-9 2009 Here we also report solution-processed ambipolar films of thiophene-based molecule 12 and copolymers P13 and P14 which exhibit electron and hole mobilities of 1 x 10(-3)-2 x 10(-4) and I(on)/I(off) ratios of approximately 10(4), representing the first examples of molecular and polymeric ambipolar semiconductors to function in air. copolymers 90-100 ribonuclease P/MRP subunit p14 Homo sapiens 109-112 19257852-2 2009 We previously demonstrated that covalent modification of Ad5 with reactive copolymers on the basis of poly(hydroxypropylmethacrylamide) can shield the virus, offering protection from neutralizing antibodies and enabling retargeting to cancer-upregulated receptors with peptide ligands (basic fibroblast growth factor [bFGF] and murine epidermal growth factor [EGF]). copolymers 75-85 Alzheimer disease, familial, type 5 Homo sapiens 57-60 19257852-2 2009 We previously demonstrated that covalent modification of Ad5 with reactive copolymers on the basis of poly(hydroxypropylmethacrylamide) can shield the virus, offering protection from neutralizing antibodies and enabling retargeting to cancer-upregulated receptors with peptide ligands (basic fibroblast growth factor [bFGF] and murine epidermal growth factor [EGF]). copolymers 75-85 epidermal growth factor Mus musculus 335-358 19257852-2 2009 We previously demonstrated that covalent modification of Ad5 with reactive copolymers on the basis of poly(hydroxypropylmethacrylamide) can shield the virus, offering protection from neutralizing antibodies and enabling retargeting to cancer-upregulated receptors with peptide ligands (basic fibroblast growth factor [bFGF] and murine epidermal growth factor [EGF]). copolymers 75-85 epidermal growth factor Mus musculus 360-363 18838162-6 2009 During the self-assembly, the PPO blocks of both block copolymers aggregated into cores that were surrounded by mixed corona chains of PLGA and PEG blocks. copolymers 55-65 protoporphyrinogen oxidase Homo sapiens 30-33 19435052-2 2009 Effective surface modification effect of BaTiO3 nanoparticles with the copolymers were observed, as evidenced by TGA, SEM, EDX and FT-IR. copolymers 71-81 T-box transcription factor 1 Homo sapiens 113-116 19147149-1 2009 Homopolymers and block copolymers of higher epoxides (butene oxide and hexene oxide) are synthesized using 1-alkanols and polyethylene glycol monomethyl ether (PEG-MME) 1100 as initiators by anionic ring opening polymerization in bulk. copolymers 23-33 membrane metalloendopeptidase Homo sapiens 164-167 18855948-0 2009 Self-assembling diblock copolymers of poly[N-(2-hydroxypropyl)methacrylamide] and a beta-sheet peptide. copolymers 24-34 amyloid beta precursor protein Homo sapiens 82-88 19111313-2 2009 Mesoporous chloromethylated polystyrene beads (MCP beads) containing dithiocarbamate iniferter (initiator transfer agent terminator) were used as supports for the grafting of lysozyme imprinted copolymers with acrylamide and N,N"-methylenebisacrylamide through surface initiated living-radical polymerization (SIP). copolymers 194-204 membrane cofactor protein Bos taurus 47-50 19133835-2 2009 The block copolymers with various molecular weights and compositions were synthesized through ring-opening polymerization of 2-ethoxy-2-oxo-1,3,2-dioxaphospholane (EEP) and 2-isopropoxy-2-oxo-1,3,2-dioxaphospholane (PEP) using poly(ethylene glycol) monomethyl ether (mPEG) as the initiator and stannous octoate as the catalyst. copolymers 10-20 progestagen associated endometrial protein Homo sapiens 216-219 19496100-1 2009 Divide and conquer: Polymer nanoparticles with phase-separation structures prepared with block copolymers and homopolymer blends were used to fabricate unique suprapolymer structures by cross-linking one polymer moiety and dissolving the other (see scheme; PI = polyisoprene, PSt = polystyrene). copolymers 95-105 sulfotransferase family 1A member 1 Homo sapiens 276-279 18393290-0 2008 Interactions of pluronic block copolymers on P-gp efflux activity: experience with HIV-1 protease inhibitors. copolymers 31-41 phosphoglycolate phosphatase Homo sapiens 45-49 18722489-2 2008 The formulation contains amphiphilic block copolymers, Pluronics, that exhibit the unique ability to chemosensitize multidrug resistant (MDR) tumors by inhibiting P-glycoprotein (Pgp) drug efflux system and enhancing pro-apoptotic signaling in cancer cells. copolymers 43-53 ATP-binding cassette, sub-family B (MDR/TAP), member 1B Mus musculus 137-140 18769873-3 2008 METHODS: We synthesized new amphiphilic copolymers in which the hydrophobic pPO block was replaced by poly(tetrahydrofuran) (pTHF) chains. copolymers 40-50 protoporphyrinogen oxidase Homo sapiens 76-79 18722489-2 2008 The formulation contains amphiphilic block copolymers, Pluronics, that exhibit the unique ability to chemosensitize multidrug resistant (MDR) tumors by inhibiting P-glycoprotein (Pgp) drug efflux system and enhancing pro-apoptotic signaling in cancer cells. copolymers 43-53 phosphoglycolate phosphatase Mus musculus 163-177 18722489-2 2008 The formulation contains amphiphilic block copolymers, Pluronics, that exhibit the unique ability to chemosensitize multidrug resistant (MDR) tumors by inhibiting P-glycoprotein (Pgp) drug efflux system and enhancing pro-apoptotic signaling in cancer cells. copolymers 43-53 phosphoglycolate phosphatase Mus musculus 179-182 18825294-5 2008 The presence of triazole units in the copolymers suppresses the formation of phosphonic acid anhydrides up to 150 degrees C, as verified by both (31)P NMR and TGA. copolymers 38-48 T-box transcription factor 1 Homo sapiens 159-162 18710282-0 2008 Thiol/acrylate-modified PEO-PPO-PEO triblocks used as reactive and thermosensitive copolymers. copolymers 83-93 protoporphyrinogen oxidase Homo sapiens 28-31 19045225-0 2008 Self-assembly of grafted Y-shaped ABC triblock copolymers in solutions. copolymers 47-57 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 34-37 18707086-1 2008 A series of well-defined poly(ethylene oxide)- b-poly(2-(diethylamino)ethyl methacrylate) (PEO- b-PDEA) diblock copolymers containing PEO block of identical chain length and PDEA block with varying degrees of polymerization (DP, in the range of 32-154) were prepared via atom transfer radical polymerization (ATRP) employing a PEO-based macroinitiator (DP = 113). copolymers 112-122 phosphodiesterase 6A Homo sapiens 98-102 19198429-2 2008 The copolymers were grafted with enantiomeric oligo(L-lactic acid) or oligo(D-lactic acid) chains using ring opening polymerization onto the PPO segment. copolymers 4-14 protoporphyrinogen oxidase Homo sapiens 141-144 18707086-2 2008 Upon a pH-jump from 3 to 12 under highly efficient stopped-flow mixing conditions, PEO- b-PDEA copolymers spontaneously form spherical micelles of increasing sizes and aggregation numbers ( N agg) with increasing PDEA chain lengths. copolymers 95-105 phosphodiesterase 6A Homo sapiens 90-94 18707086-2 2008 Upon a pH-jump from 3 to 12 under highly efficient stopped-flow mixing conditions, PEO- b-PDEA copolymers spontaneously form spherical micelles of increasing sizes and aggregation numbers ( N agg) with increasing PDEA chain lengths. copolymers 95-105 phosphodiesterase 6A Homo sapiens 213-217 18707086-9 2008 It was found that during micellization, copolymers with longer PDEA blocks exhibit much lower E a compared to those with shorter blocks. copolymers 40-50 phosphodiesterase 6A Homo sapiens 63-67 18608590-10 2008 ELPs can be modified with chemotherapeutics, are biodegradable, are biocompatible, have low immunogenicity, and have terminal pharmacokinetic half-lives >8 h. ELP block copolymers can reversibly form micelles in response to hyperthermia, and this behavior can modulate the binding avidity of peptide ligands. copolymers 172-182 nuclear receptor subfamily 5 group A member 1 Homo sapiens 0-3 18576393-3 2008 The presence of the bulky isopropyl substituents on silicon would render each of the monomeric units in these copolymers to favor a syn-syn conformation. copolymers 110-120 synemin Homo sapiens 132-135 18576393-3 2008 The presence of the bulky isopropyl substituents on silicon would render each of the monomeric units in these copolymers to favor a syn-syn conformation. copolymers 110-120 synemin Homo sapiens 136-139 18647087-3 2008 We previously established that copolymers made of poly(ethylene imine) (PEI) and poly(ethylene glycol) (PEG) enhanced ESO transfection in skeletal muscle of mdx mice, resulting in widespread distribution of dystrophin-positive fibers, but limited dystrophin expression by Western blot. copolymers 31-41 dystrophin, muscular dystrophy Mus musculus 207-217 18598063-0 2008 Effect of PEG crystallization on the self-assembly of PEG/peptide copolymers containing amyloid peptide fragments. copolymers 66-76 progestagen associated endometrial protein Homo sapiens 10-13 18513929-3 2008 Pemulen TR1 and Pemulen TR2 are cross-linked block copolymers of poly(acrylic acid) and hydrophobic long-chain methacrylates. copolymers 51-61 taste 1 receptor member 1 Homo sapiens 8-11 18513929-3 2008 Pemulen TR1 and Pemulen TR2 are cross-linked block copolymers of poly(acrylic acid) and hydrophobic long-chain methacrylates. copolymers 51-61 nuclear receptor subfamily 2 group C member 1 Homo sapiens 24-27 18456319-2 2008 The copolymers were characterized by GPC, NMR, FTIR, XRD, DSC and TGA. copolymers 4-14 glycophorin C (Gerbich blood group) Homo sapiens 37-40 18456319-2 2008 The copolymers were characterized by GPC, NMR, FTIR, XRD, DSC and TGA. copolymers 4-14 desmocollin 3 Homo sapiens 58-61 18456319-2 2008 The copolymers were characterized by GPC, NMR, FTIR, XRD, DSC and TGA. copolymers 4-14 T-box transcription factor 1 Homo sapiens 66-69 18417330-3 2008 ATR-FTIR analysis revealed differences in copolymer composition and based on the copolymer properties, a selection of copolymers was chosen to cast drug-loaded, microporous films that exhibit microencapsulation of drug agglomerates. copolymers 118-128 ATR serine/threonine kinase Homo sapiens 0-3 18647087-3 2008 We previously established that copolymers made of poly(ethylene imine) (PEI) and poly(ethylene glycol) (PEG) enhanced ESO transfection in skeletal muscle of mdx mice, resulting in widespread distribution of dystrophin-positive fibers, but limited dystrophin expression by Western blot. copolymers 31-41 dystrophin, muscular dystrophy Mus musculus 247-257 18433272-1 2008 Two oxyethylene/oxybutylene block copolymers (E(40)B(79) and E(47)B(62)), which exhibit body-centered cubic sphere (bcc) and hexagonally packed cylindrical (hex) melt morphologies in bulk, respectively, were blended with nanoclay of montmorillonite (MMT). copolymers 34-44 hematopoietically expressed homeobox Homo sapiens 125-128 18601379-1 2008 The order-disorder and order-order transitions (ODT and OOT) in the linear multiblock copolymers with two-length scale architecture A(fmN)(B(N2)A(N2))(n)B((1-f)mN) are studied under intermediate cooling below the ODT critical point where a nonconventional sequence of the OOTs was predicted previously [Smirnova et al., J. Chem. copolymers 86-96 formin 1 Homo sapiens 134-137 17896776-4 2008 On the blends of copolymers with PEO blocks of MW 2000 and 5000, fibrinogen adsorption from physiologic buffer decreased with increasing copolymer content up to 20 wt%. copolymers 17-27 fibrinogen beta chain Homo sapiens 65-75 18393523-1 2008 The interactions of bovine serum albumin (BSA) with three ethylene oxide/butylene oxide (E/B) copolymers having different block lengths and varying molecular architectures is examined in this study in aqueous solutions. copolymers 94-104 albumin Homo sapiens 27-40 18384691-6 2008 Three weekly intramuscular injections of 5 microg of ESO complexed with PEI2K-PEG550 copolymers resulted in about 500 dystrophin-positive fibers and about 12% of normal levels of dystrophin expression at 3 weeks after the initial injection, which is significantly greater than for injections of ESO alone, which are known to be almost completely ineffective. copolymers 85-95 dystrophin, muscular dystrophy Mus musculus 118-128 18234389-7 2008 When human growth hormone (hGH) was incorporated in the strereocomplexed multi-block Pluronic copolymers, hGH was released out in a sustained and zero-order fashion for 13 days by a diffusion/erosion coupled mechanism. copolymers 94-104 growth hormone 1 Homo sapiens 11-25 18384691-6 2008 Three weekly intramuscular injections of 5 microg of ESO complexed with PEI2K-PEG550 copolymers resulted in about 500 dystrophin-positive fibers and about 12% of normal levels of dystrophin expression at 3 weeks after the initial injection, which is significantly greater than for injections of ESO alone, which are known to be almost completely ineffective. copolymers 85-95 dystrophin, muscular dystrophy Mus musculus 179-189 18324775-2 2008 Copolymers were injectable at or below room temperature and formed robust hydrogels at 37 degrees C. The effects of monomer ratio, polylactide length, and AAc content on the chemical and physical properties of the hydrogel were investigated. copolymers 0-10 glycine-N-acyltransferase Homo sapiens 155-158 18426382-6 2008 RESULTS/CONCLUSION: The published results on oral insulin delivery devices, particularly on inter-polymer complexes of the grafted copolymers, are discussed in greater depth. copolymers 131-141 insulin Homo sapiens 50-57 18341271-6 2008 The data collected demonstrate that the rhodamine B covalently attached to the amphiphilic copolymers is bioaccumulated without being translocated out of the cell by the multixenobiotic resistance (MXR) transporters. copolymers 91-101 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 198-201 18341271-7 2008 As the MXR system is similar to the multidrug resistance (MDR) first observed in tumor cell lines resistant to anticancer drugs, the present data confirm the significant role that amphiphilic copolymers can play in the ongoing development of drug delivery strategies to overcome multidrug resistance. copolymers 192-202 ATP binding cassette subfamily G member 2 (Junior blood group) Homo sapiens 7-10 18281978-2 2008 The resulting copolymers were characterized by 1H NMR, elemental analysis, GPC, TGA, and DSC. copolymers 14-24 glycophorin C (Gerbich blood group) Homo sapiens 75-78 18281978-2 2008 The resulting copolymers were characterized by 1H NMR, elemental analysis, GPC, TGA, and DSC. copolymers 14-24 T-box transcription factor 1 Homo sapiens 80-83 18517411-0 2008 Morphological transition behavior of ABC star copolymers by varying the interaction parameters. copolymers 46-56 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 37-40 18359690-0 2008 [Phase transfer catalyzed bioconversion of penicillin G to 6-APA by immobilized penicillin acylase in recyclable aqueous two-phase systems with light/pH sensitive copolymers]. copolymers 163-173 aminoacylase 1 Homo sapiens 91-98 18081338-3 2008 Random copolymers displayed an interaction similar to that observed with other hydrophilic homopolymers with the additional characteristic that the intensity of the interaction increased with the increase in the copolymer hydrophobicity (as determined by its PO content), revealing that these copolymers display an intermediate behavior between PEO and PPO. copolymers 7-17 protoporphyrinogen oxidase Homo sapiens 353-356 18081338-3 2008 Random copolymers displayed an interaction similar to that observed with other hydrophilic homopolymers with the additional characteristic that the intensity of the interaction increased with the increase in the copolymer hydrophobicity (as determined by its PO content), revealing that these copolymers display an intermediate behavior between PEO and PPO. copolymers 293-303 protoporphyrinogen oxidase Homo sapiens 353-356 19137061-0 2008 Cationic nano-copolymers mediated IKKbeta targeting siRNA inhibit the proliferation of human Tenon"s capsule fibroblasts in vitro. copolymers 14-24 inhibitor of nuclear factor kappa B kinase subunit beta Homo sapiens 34-41 18163573-0 2008 In situ cross-linking of elastin-like polypeptide block copolymers for tissue repair. copolymers 56-66 elastin Homo sapiens 25-32 18163573-3 2008 All ELP block copolymers were rapidly cross-linked with HMPs within several minutes under physiological conditions. copolymers 14-24 nuclear receptor subfamily 5 group A member 1 Homo sapiens 4-7 17455282-1 2008 A series of biodegradable PCL-PEG-PCL block copolymers were successfully synthesized by ring-opening polymerization of epsilon-caprolactone initiated by poly(ethylene glycol) (PEG), which were characterized by (1)H NMR, (13)C NMR, and FTIR. copolymers 44-54 PHD finger protein 1 Homo sapiens 26-29 17455282-1 2008 A series of biodegradable PCL-PEG-PCL block copolymers were successfully synthesized by ring-opening polymerization of epsilon-caprolactone initiated by poly(ethylene glycol) (PEG), which were characterized by (1)H NMR, (13)C NMR, and FTIR. copolymers 44-54 PHD finger protein 1 Homo sapiens 34-37 17935731-6 2008 In alkaline solution, analysis of the adsorption data suggests a conformation for the adsorbed copolymers where one block projects normal to the solid/liquid interface; this layer consists of a hydrophobic PDEA anchor block adsorbed on the silica surface and an anionic PMAA buoy block extending into the solution phase. copolymers 95-105 phosphodiesterase 6A Homo sapiens 206-210 18039006-3 2007 In this project, we exploited the environmental application of protein-based block copolymers based on elastin-like protein (ELP) sequences. copolymers 83-93 nuclear receptor subfamily 5 group A member 1 Homo sapiens 103-123 17724789-2 2007 The copolymers were characterized with IR spectroscopy, elemental analysis, DSC, and TGA. copolymers 4-14 T-box transcription factor 1 Homo sapiens 85-88 18039006-3 2007 In this project, we exploited the environmental application of protein-based block copolymers based on elastin-like protein (ELP) sequences. copolymers 83-93 nuclear receptor subfamily 5 group A member 1 Homo sapiens 125-128 19459290-4 2007 Since pi-shaped ABC block copolymers can reduce to linear ABC and star ABC block copolymers, they are good model copolymers for studying the self-assembly of complex block copolymers into micelles or vesicles. copolymers 26-36 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 58-61 18025277-2 2007 To enhance delivery and solubility of these prodrugs, macromolecular carriers consisting of N-(2-hydroxypropyl) methacrylamide (HPMA)-based copolymers were covalently coupled to a PSA-activated peptide prodrug. copolymers 140-150 kallikrein B, plasma 1 Mus musculus 180-183 19459290-0 2007 Multicompartment micelles and vesicles from pi-shaped ABC block copolymers: a dissipative particle dynamics study. copolymers 64-74 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 54-57 19459290-1 2007 Dissipative particle dynamics simulations were performed on the morphology and structure of multicompartment micelles and vesicles formed from pi-shaped ABC block copolymers in water. copolymers 163-173 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 153-156 19459290-4 2007 Since pi-shaped ABC block copolymers can reduce to linear ABC and star ABC block copolymers, they are good model copolymers for studying the self-assembly of complex block copolymers into micelles or vesicles. copolymers 26-36 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 58-61 19459290-4 2007 Since pi-shaped ABC block copolymers can reduce to linear ABC and star ABC block copolymers, they are good model copolymers for studying the self-assembly of complex block copolymers into micelles or vesicles. copolymers 26-36 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 16-19 19459290-4 2007 Since pi-shaped ABC block copolymers can reduce to linear ABC and star ABC block copolymers, they are good model copolymers for studying the self-assembly of complex block copolymers into micelles or vesicles. copolymers 81-91 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 16-19 19459290-4 2007 Since pi-shaped ABC block copolymers can reduce to linear ABC and star ABC block copolymers, they are good model copolymers for studying the self-assembly of complex block copolymers into micelles or vesicles. copolymers 81-91 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 16-19 19459290-4 2007 Since pi-shaped ABC block copolymers can reduce to linear ABC and star ABC block copolymers, they are good model copolymers for studying the self-assembly of complex block copolymers into micelles or vesicles. copolymers 81-91 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 16-19 17655339-0 2007 1H NMR spectroscopic investigations on the micellization and gelation of PEO-PPO-PEO block copolymers in aqueous solutions. copolymers 91-101 protoporphyrinogen oxidase Homo sapiens 77-80 17691844-2 2007 The polymerization was found to proceed with the expected living behavior resulting in block copolymers with varying block sizes of low polydispersity (PDI <1.3). copolymers 93-103 peptidyl arginine deiminase 1 Homo sapiens 152-155 17665415-1 2007 We here present the synthesis and characterisation of linear and star-shaped amphiphilic block copolymers based on hydrophobic polysulfides (poly(propylene sulfide), PPS) and hydrophilic polyethers (poly(ethylene glycol), PEG). copolymers 95-105 progestagen associated endometrial protein Homo sapiens 222-225 17323321-1 2007 Well-defined biodegradable poly(epsilon-caprolactone)-b-poly(ethylene oxide) (PCL-b-PEO) copolymers with different arms were synthesized via controlled ring-opening polymerization of epsilon-caprolactone, followed by coupling reaction with carboxyl-terminated PEO, where these copolymers included both star-shaped copolymers having four and six arms and linear analogues having one and two arms. copolymers 89-99 twinkle mtDNA helicase Homo sapiens 84-87 17323321-2 2007 When the weight percent of both PCL and PEO blocks within copolymer was similar to each other, the maximal melting temperature, the crystallization temperature, degree of crystallinity, and the spherulitic growth rate of these copolymers decreased with the increasing arm number of polymer. copolymers 227-237 twinkle mtDNA helicase Homo sapiens 40-43 17685646-1 2007 The interaction of hydrophobically modified copolymers of acrylamide and acrylic acid, designated as PAM-C12-AA (X%) (X% indicates the percentage of acrylic acid unit and X = 5, 10, 20), with dimyristoylphosphatidylcholine (DMPC) vesicles has been studied. copolymers 44-54 peptidylglycine alpha-amidating monooxygenase Homo sapiens 101-104 17481869-5 2007 The present review provides a concise description of the most important applications of PEO-PPO-based copolymers in the Pharmaceutical Technology field as means for attaining improved solubility, stability, release, and bioavailability of drugs. copolymers 102-112 twinkle mtDNA helicase Homo sapiens 88-91 17383837-2 2007 The interactions between these copolymers and porcine stomach mucin have been studied in aqueous solutions using dynamic light scattering, zeta-potential measurements, turbidimetric titration and transmission electron microscopy (TEM). copolymers 31-41 LOC100508689 Homo sapiens 62-67 17383837-3 2007 It was demonstrated that mixing aqueous dispersions of mucin with solutions of the cationic copolymers results in significant changes in size distribution and zeta-potential of its particles. copolymers 92-102 LOC100508689 Homo sapiens 55-60 17383837-4 2007 It was found that an increase in the content of hydrophobic groups in copolymers leads to more efficient adsorption of macromolecules on the surface of mucin particles, which evidences the importance of hydrophobic effects in mucoadhesion. copolymers 70-80 LOC100508689 Homo sapiens 152-157 17387596-6 2007 The cells on GRGDSG-grafted copolymers were able to form vinculin-containing focal adhesion plaques, to synthesize DNA and even proliferate in a serum-free medium, which indicates specific binding to the GRGDSG sequences through their adhesion receptors. copolymers 28-38 vinculin Rattus norvegicus 57-65 17481869-5 2007 The present review provides a concise description of the most important applications of PEO-PPO-based copolymers in the Pharmaceutical Technology field as means for attaining improved solubility, stability, release, and bioavailability of drugs. copolymers 102-112 protoporphyrinogen oxidase Homo sapiens 92-95 17439172-3 2007 Such interactions influence the self-assembly properties of the block copolymer in solution by increasing the hydration of the block copolymers and stabilizing the gauche conformation of the PPO chain. copolymers 133-143 protoporphyrinogen oxidase Homo sapiens 191-194 17499069-0 2007 Use of chemically modified thermoresponsive copolymers for the detection of C-reactive protein. copolymers 44-54 C-reactive protein Homo sapiens 76-94 17206625-6 2007 The effect of HEMA content in the copolymers on complement activation (production of C3a) was investigated in an in vitro test. copolymers 34-44 complement C3 Homo sapiens 85-88 17439172-4 2007 Therefore, urea increases the critical micellization temperature (CMT) values of PEO-PPO-PEO copolymers, and the effect of urea on the CMT is more pronounced for copolymers with higher PEO contents and lower for those with increased contents of PPO segments. copolymers 93-103 protoporphyrinogen oxidase Homo sapiens 85-88 17257817-1 2007 Methoxy poly(ethylene glycol)-b-poly(caprolactone) (MePEG-b-PCL) copolymers with varying PEG block lengths and a constant PCL block length were synthesized by cationic ring-opening polymerization and used to form nano-sized micelles. copolymers 65-75 polycystic kidney disease 2-like 1 Mus musculus 60-63 17315925-0 2007 Characterization of the soluble nanoparticles formed through Coulombic interaction of bovine serum albumin with anionic graft copolymers at low pH. copolymers 126-136 albumin Homo sapiens 93-106 17508831-2 2007 At low pH values these copolymers spontaneously adsorb on the negatively charged mica surfaces from aqueous solutions as a consequence of the positive charge of the polylysine moieties. copolymers 23-33 MHC class I polypeptide-related sequence A Homo sapiens 81-85 17279703-2 2007 PEO/PPO block-copolymers are generally soluble in xylene but without forming aggregates. copolymers 14-24 protoporphyrinogen oxidase Homo sapiens 4-7 17249707-8 2007 New multifunctional amphiphilic rod-coil block copolymers, poly-[2,7-(9,9-di-n-hexylfluorene)]-block-poly-[poly(ethylene glycol) methyl ether methacrylate]-block-poly-[3(tripropoxysilyl)propyl methacrylate] (PF-b-PPEGMA-b-PPOPS), with two different block ratios were synthesized and used to prepare the corresponding polymer brushes via the grafting- method. copolymers 47-57 keratin 75 Homo sapiens 208-212 17196543-7 2007 For instance serum albumin was found to interact with copolymers of low hydrophilic-lipophilic balance values and poly(propylene oxide) contaminants, whereas this interaction was not significant with the relatively hydrophilic IgG. copolymers 54-64 albumin Homo sapiens 19-26 17253738-0 2007 Effect of ionic liquids on the aggregation behavior of PEO-PPO-PEO block copolymers in aqueous solution. copolymers 73-83 protoporphyrinogen oxidase Homo sapiens 59-62 17220971-0 2007 Synthesis of well-defined Locust Bean Gum-graft-copolymers using ambient aqueous atom transfer radical polymerisation. copolymers 48-58 brain expressed associated with NEDD4 1 Homo sapiens 33-37 17055046-1 2007 Pluronic block copolymers (PBCs) have been shown to reverse multidrug resistance (MDR) by inhibiting the P-glycoprotein (P-gp) pump in cancer cells. copolymers 15-25 ATP binding cassette subfamily B member 1 Homo sapiens 105-119 17055046-1 2007 Pluronic block copolymers (PBCs) have been shown to reverse multidrug resistance (MDR) by inhibiting the P-glycoprotein (P-gp) pump in cancer cells. copolymers 15-25 ATP binding cassette subfamily B member 1 Homo sapiens 121-125 17042041-1 2007 Amphiphilic copolymers (random P1 and block P2) based on 2-oxazolines were synthesised with triphenylphosphane ligands covalently linked to the polymers by means of a metal-free synthesis route. copolymers 12-22 crystallin gamma F, pseudogene Homo sapiens 31-46 17042041-6 2007 Copolymers P3 and P4 showed, under identical reaction conditions, strong isomerisation after 40-60 % conversion (n/iso approximately 0.7) and maximum activities of 1560 h(-1) (P3) and 1330 h(-1) (P4) at a concentration of 5 x 10(-3) mol L(-1). copolymers 0-10 exosome component 10 Homo sapiens 11-20 17042541-2 2006 The block copolymers consist of a hydrophilic PEO core with hydrophobic PCL chains at the star periphery. copolymers 10-20 PHD finger protein 1 Homo sapiens 72-75 17073495-1 2006 In the present work, copolymers of vinylphosphonic acid and 4-vinilyimidazole (poly(4-VIm-co-VPA)) were found to be substrates favoring the precipitation of nanohydroxyapatite (HAP) crystals from stable supersaturated solutions at pH 7.4 and 37 degrees C. Deposition kinetics were studied by the constant composition technique. copolymers 21-31 vimentin Homo sapiens 86-89 17073495-1 2006 In the present work, copolymers of vinylphosphonic acid and 4-vinilyimidazole (poly(4-VIm-co-VPA)) were found to be substrates favoring the precipitation of nanohydroxyapatite (HAP) crystals from stable supersaturated solutions at pH 7.4 and 37 degrees C. Deposition kinetics were studied by the constant composition technique. copolymers 21-31 reticulon 3 Homo sapiens 177-180 17042541-6 2006 In the same pressure region, the star-shaped block copolymers undergo a phase transition corresponding to the collapse and the crystallization of the PCL chains as shown by the presence of a pseudoplateau in the isotherms. copolymers 51-61 PHD finger protein 1 Homo sapiens 150-153 17042541-8 2006 AFM imaging confirmed the formation of PCL crystals in the LB monolayers of the PCL homopolymers and of the copolymers, but also showed that the PCL segments can undergo additional crystallization after monolayer transfer during water evaporation. copolymers 108-118 PHD finger protein 1 Homo sapiens 39-42 16563878-0 2006 Preparation of biosensors by immobilization of polyphenol oxidase in conducting copolymers and their use in determination of phenolic compounds in red wine. copolymers 80-90 protoporphyrinogen oxidase Homo sapiens 47-65 16563878-4 2006 Novel biosensors for phenolic compounds were constructed by immobilizing polyphenol oxidase (PPO) into conducting copolymers prepared by electropolymerization of pyrrole with thiophene capped polytetrahydrofuran. copolymers 114-124 protoporphyrinogen oxidase Homo sapiens 73-91 16563878-4 2006 Novel biosensors for phenolic compounds were constructed by immobilizing polyphenol oxidase (PPO) into conducting copolymers prepared by electropolymerization of pyrrole with thiophene capped polytetrahydrofuran. copolymers 114-124 protoporphyrinogen oxidase Homo sapiens 93-96 16564085-6 2006 The PLA-TPGS copolymers of various PLA:TPGS ratios were synthesized by the ring-opening polymerization method and characterized by GPC and (1)H NMR for their molecular structure. copolymers 13-23 glycophorin C (Gerbich blood group) Homo sapiens 131-134 16800009-4 2006 These acetylene-functionalized, Click-readied amphiphilic block copolymers were then self-assembled and cross-linked to afford shell cross-linked knedel-like (SCK) nanoparticles that contained acetylene groups in the core domain. copolymers 64-74 SHC adaptor protein 2 Homo sapiens 127-157 16800009-4 2006 These acetylene-functionalized, Click-readied amphiphilic block copolymers were then self-assembled and cross-linked to afford shell cross-linked knedel-like (SCK) nanoparticles that contained acetylene groups in the core domain. copolymers 64-74 SHC adaptor protein 2 Homo sapiens 159-162 16713691-2 2006 MPEG-PmHLA and MPEG-PdiHLA copolymers of predictable molecular weights and narrow polydispersities were obtained, as shown by (1)H NMR and GPC. copolymers 27-37 glycophorin C (Gerbich blood group) Homo sapiens 139-142 16903670-3 2006 A series of novel biodegradable copolymers with different compositions were characterized by (1)H NMR, (13)C NMR, and GPC. copolymers 32-42 glycophorin C (Gerbich blood group) Homo sapiens 118-121 16903690-2 2006 Accordingly, we synthesized two hybrid multiblock copolymers by condensing poly(alanine) [(Ala)(5)] blocks of the structural proteins (spidroin MaSp1 and MaSp2) of spider dragline silk with different oligomers of isoprene (2200 and 5000 Da) having reactive end groups. copolymers 50-60 MBL associated serine protease 1 Homo sapiens 144-149 16903690-2 2006 Accordingly, we synthesized two hybrid multiblock copolymers by condensing poly(alanine) [(Ala)(5)] blocks of the structural proteins (spidroin MaSp1 and MaSp2) of spider dragline silk with different oligomers of isoprene (2200 and 5000 Da) having reactive end groups. copolymers 50-60 MBL associated serine protease 2 Homo sapiens 154-159 16869582-4 2006 As a result, the adsorption behavior of PDMA-PDEA diblock copolymers on silica is strongly dependent on both the copolymer concentration and the solution pH. copolymers 58-68 phosphodiesterase 6A Homo sapiens 45-49 16869582-5 2006 Below the cmc at pH 9, the cationic PDMA-PDEA copolymers adsorb as unimers and the conformation of the adsorbed polymer is essentially flat. copolymers 46-56 phosphodiesterase 6A Homo sapiens 41-45 16819846-6 2006 DSC and TGA measurements revealed the high thermal stability of the alternating copolymers containing bulky, stiff, and strain-free adamantane skeletons. copolymers 80-90 T-box transcription factor 1 Homo sapiens 8-11 19810330-10 2005 Moreover, the parent copolymers may properly functionalize the RD surface by exploiting both their high affinity to the solid surface and the ability to self-assemble onto it as L35 and 10R5 clearly showed. copolymers 21-31 ribosomal protein L35 Homo sapiens 178-181 16768404-0 2006 Reversibility of structural transition of cytochrome c on interacting with and releasing from alternating copolymers of maleic Acid and alkene. copolymers 106-116 cytochrome c, somatic Homo sapiens 42-54 16602737-6 2006 Indeed, equimolar mixtures of the graft copolymers, CCE-P/CCK-P, have been observed to self-assemble into hydrogels in PBS solution at neutral pH at concentrations as low as 0.1 wt %. copolymers 40-50 cholecystokinin Homo sapiens 58-61 16374773-2 2006 Copolymers with different monomer feed ratios were prepared and characterized with IR, NMR, and GPC. copolymers 0-10 glycophorin C (Gerbich blood group) Homo sapiens 96-99 16343010-1 2005 Poly(L-lysine)-g-poly(ethylene glycol) (PLL-g-PEG) copolymers with various grafting ratios were adsorbed to niobium pentoxide-coated silicon wafers and characterized before and after protein adsorption using X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (ToF-SIMS). copolymers 51-61 progestagen associated endometrial protein Homo sapiens 46-49 16274831-3 2005 Upon radiolabeling, the copolymers were injected i.v., and their circulation kinetics, tissue distribution and tumor accumulation were monitored in rats bearing subcutaneous Dunning AT1 tumors. copolymers 24-34 angiotensin II receptor, type 1a Rattus norvegicus 182-185 16488666-7 2006 Surprisingly, injections of AO complexed with high Mw PEI25000(PEG5000) copolymers, which formed smaller nonaggregated particles, produced about threefold fewer dystrophin-positive fibers than injections of the low Mw polyplexes. copolymers 72-82 dystrophin, muscular dystrophy Mus musculus 161-171 16800514-0 2006 Comparing the morphology and phase diagram of H-shaped ABC block copolymers and linear ABC block copolymers. copolymers 65-75 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 55-58 16800514-0 2006 Comparing the morphology and phase diagram of H-shaped ABC block copolymers and linear ABC block copolymers. copolymers 97-107 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 87-90 16616967-2 2006 Double emulsion (DE) and nanoprecipitation (NP) methods were used to fabricate the nanoparticles of these copolymers entrapping bovine serum albumin (BSA) as a model protein. copolymers 106-116 albumin Homo sapiens 135-148 16509700-9 2006 The bulky PPV copolymers showed that both the luminescence intensity (in film) and quantum yields (in solution) increased with an increase in the extent of BTCD incorporation in the MEH-PPV and attained a maximum for 50% BTCD. copolymers 14-24 Kin17 DNA and RNA binding protein Homo sapiens 156-160 16509700-9 2006 The bulky PPV copolymers showed that both the luminescence intensity (in film) and quantum yields (in solution) increased with an increase in the extent of BTCD incorporation in the MEH-PPV and attained a maximum for 50% BTCD. copolymers 14-24 epoxide hydrolase 1 Homo sapiens 182-185 16509700-9 2006 The bulky PPV copolymers showed that both the luminescence intensity (in film) and quantum yields (in solution) increased with an increase in the extent of BTCD incorporation in the MEH-PPV and attained a maximum for 50% BTCD. copolymers 14-24 Kin17 DNA and RNA binding protein Homo sapiens 221-225 16324807-3 2006 The incorporation and circulation stability of CPT micelles were evaluated by measuring the CPT in micelle using gel-permeation chromatography and by CPT concentration measurement after intravenous injection using HPLC, respectively, in terms of chemical structure of block copolymers. copolymers 274-284 choline phosphotransferase 1 Homo sapiens 47-50 24058234-3 2006 Aqueous micellar solutions of the block copolymers were prepared and characterized by static and dynamic light scattering analysis (DLS and SLS). copolymers 40-50 aldehyde dehydrogenase 3 family member A2 Homo sapiens 140-143 16231078-3 2005 Our method, applied to a surfactant lamellar phase system decorated by amphiphilic copolymers, provides excellent fits for any intermembrane spacing or membrane concentration over the entire q-range of the SANS experiments. copolymers 83-93 USH1 protein network component sans Homo sapiens 206-210 16170693-2 2005 METHODS: Insulin nanocomplexes were prepared from chitosan and its copolymers by self-assembly. copolymers 67-77 insulin Homo sapiens 9-16 16262334-0 2005 Interactions of apo cytochrome C with alternating copolymers of maleic acid and alkene. copolymers 50-60 cytochrome c, somatic Homo sapiens 20-32 16283722-2 2005 Our model copolymers are based on the primary structures of the major bovine casein monomers, alpha(s1)-casein and beta-casein. copolymers 10-20 casein alpha s1 Bos taurus 94-110 16283722-2 2005 Our model copolymers are based on the primary structures of the major bovine casein monomers, alpha(s1)-casein and beta-casein. copolymers 10-20 casein beta Bos taurus 115-126 15653162-2 2005 To unite enzyme delivery by PNC with a clinically relevant goal of containment of vascular oxidative stress, a novel freeze-thaw encapsulation strategy was designed and provides approximately 20% efficiency loading of an active large antioxidant enzyme, catalase, into PNC (200-300 nm) composed of biodegradable block copolymers poly(ethylene glycol)-b-poly(lactic-glycolic acid). copolymers 318-328 catalase Homo sapiens 254-262 16042444-1 2005 Micelles of ABC block copolymers with varying degrees of polymerization of the B block (n) and constant lengths of the A and C blocks were investigated by small-angle X-ray scattering (SAXS), analytical ultracentrifugation (AUC), surface tension measurements, and isothermal titration calorimetry. copolymers 22-32 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 12-15 16089378-2 2005 The amount of MO loaded was potentially controlled by changing the dye concentrations, film thickness, and AAc content of the copolymers. copolymers 126-136 glycine-N-acyltransferase Homo sapiens 107-110 16089412-1 2005 Gold nanoparticles of improved stability against aggregation were prepared using poly(ethylene oxide)-block-poly(epsilon-caprolactone) (PEO-b-PCL) star-block copolymers. copolymers 158-168 PHD finger protein 1 Homo sapiens 142-145 16851902-6 2005 In step 2, the adsorption of block copolymers on the surface of gold clusters takes place because of the amphiphilic character of the block copolymer (hydrophobicity of PPO). copolymers 35-45 protoporphyrinogen oxidase Homo sapiens 169-172 16851902-7 2005 The much higher efficiency of particle formation attained in the PEO-PPO-PEO block copolymer systems as compared to PEO homopolymer systems can be attributed to the adsorption and growth processes (steps 2 and 3) facilitated by the block copolymers. copolymers 238-248 protoporphyrinogen oxidase Homo sapiens 69-72 15723471-0 2005 Lamellar-to-cubic phase change in phospholipid bilayer systems incorporated with block copolymers: DMPC and PEO-PPO-PEO (P85). copolymers 87-97 protoporphyrinogen oxidase Homo sapiens 112-115 15723476-1 2005 The drying of hydrogel films formed by poly(ethylene oxide)-poly(propylene oxide) (PEO-PPO) block copolymers (Pluronic P105 and Pluronic L64) is investigated at various air relative humidity (RH) conditions in the range 11-94%. copolymers 98-108 protoporphyrinogen oxidase Homo sapiens 87-90 15723476-8 2005 Two distinct regions (liquid/gel and solid/crystalline) are observed in the drying isotherm for PEO-PPO block copolymers and homopolymer poly(ethylene glycol)s. copolymers 110-120 protoporphyrinogen oxidase Homo sapiens 100-103 15620860-8 2005 The effects of varying block lengths and concentrations of copolymers on the in vitro release of lysozyme were evaluated. copolymers 59-69 lysozyme Homo sapiens 97-105 15620860-10 2005 Increasing the block lengths of copolymers decreased burst release of lysozyme from 41.2+/-5.4% to 16.1+/-3.9%. copolymers 32-42 lysozyme Homo sapiens 70-78 15483144-0 2004 Isolation and characterization of copolymers of beta-lactoglobulin, alpha-lactalbumin, kappa-casein, and alphas1-casein generated by pressurization and thermal treatment of raw milk. copolymers 34-44 lactalbumin alpha Homo sapiens 68-85 15647894-6 2004 We attribute the fast process in the bcc state to concentration fluctuations of the micellar cores (PEP), relaxing by mutual diffusion of the micelles with copolymers dissolved in the PDMS matrix. copolymers 156-166 progestagen associated endometrial protein Homo sapiens 100-103 15483144-0 2004 Isolation and characterization of copolymers of beta-lactoglobulin, alpha-lactalbumin, kappa-casein, and alphas1-casein generated by pressurization and thermal treatment of raw milk. copolymers 34-44 casein kappa Homo sapiens 87-99 15483144-3 2004 Approximately half of the beta-lactoglobulin formed polymers, and the other half formed large copolymers, mainly with kappa-casein, alpha-lactalbumin via intermolecular disulfide bond exchange, and alpha(s1)-casein via physicochemical interactions, in proportions of 1.0:0.7:0.3:0.1, respectively. copolymers 94-104 casein kappa Homo sapiens 118-130 15610618-2 2004 Copolymers with different molar masses at a constant lactide/glycolide ratio were used for preparation of bovine serum albumin (BSA)-loaded microparticles by the double emulsion w/o/w method. copolymers 0-10 albumin Homo sapiens 113-126 15490442-5 2004 Here we describe a new approach to induce a directed insertion of membrane proteins into asymmetric membranes formed by amphiphilic ABC triblock copolymers with two chemically different water-soluble blocks A and C. In a comparative study we have reconstituted His-tag labeled Aquaporin 0 in lipid, ABA block copolymer, and ABC block copolymer vesicles. copolymers 145-155 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 132-135 15468216-6 2004 The graft copolymers contained from 0.5 to 14 mol-% of PHB blocks, with a glass transition temperature decreasing from 100 to 3 degrees C. copolymers 10-20 prohibitin 1 Homo sapiens 55-58 15271568-4 2004 Block copolymers with comparably long PPO and PEO segment lengths, such as F127 and F108, most effectively protected DOPE liposomes prepared at high pH from aggregation and subsequent structural rearrangements induced by acidification. copolymers 6-16 protoporphyrinogen oxidase Homo sapiens 38-41 15271570-1 2004 The micellization of PEO-PPO-PEO block copolymers in p-xylene has been studied in the presence of CO2. copolymers 39-49 protoporphyrinogen oxidase Homo sapiens 25-28 15271570-5 2004 With the suitable composition and molecular weight, the critical micelle pressure (CMP) of copolymers decreases with the increase in the lengths of PEO and PPO blocks due to the hydrophilic and folding effects, respectively. copolymers 91-101 protoporphyrinogen oxidase Homo sapiens 156-159 15093592-6 2004 The copolymers were shown to open the tight junctions between cells, increasing the available area for diffusion across the cell monolayer, and thus increasing the permeability of insulin across the monolayer. copolymers 4-14 insulin Homo sapiens 180-187 15063028-6 2004 Poration occurs as the hydrophobic PLA or PCL block is hydrolytically scissioned, progressively generating an increasing number of pore-preferring copolymers in the membrane. copolymers 147-157 polycystin 2 like 1, transient receptor potential cation channel Homo sapiens 42-45 15292514-6 2004 The generation of these copolymer-specific regulatory T cells that secrete IL-4 and IL-10 and are independent of the immunizing autoantigen is very prominent among the multiple mechanisms that account for the observed suppressive effect of copolymers in EAE. copolymers 240-250 interleukin 4 Mus musculus 75-79 15292514-6 2004 The generation of these copolymer-specific regulatory T cells that secrete IL-4 and IL-10 and are independent of the immunizing autoantigen is very prominent among the multiple mechanisms that account for the observed suppressive effect of copolymers in EAE. copolymers 240-250 interleukin 10 Mus musculus 84-89 15212885-1 2004 The capability of a family of copolymers comprising Pluronic (PEO-PPO-PEO) surfactants covalently conjugated with poly(acrylic acid) (Pluronic-PAA) to enhance the aqueous solubility and stability of the lactone form of camptothecin (CPT) was studied. copolymers 30-40 protoporphyrinogen oxidase Homo sapiens 66-69 15158974-5 2004 Copolymerization of NIPA with acrylic acid (AAc) allows the synthesis of both pH and temperature-responsive copolymers. copolymers 108-118 zinc finger C3HC-type containing 1 Homo sapiens 20-24 15158974-5 2004 Copolymerization of NIPA with acrylic acid (AAc) allows the synthesis of both pH and temperature-responsive copolymers. copolymers 108-118 glycine-N-acyltransferase Homo sapiens 44-47 15158974-6 2004 This paper summarizes some of our related studies in which NIPA and its copolymers were synthesized and used as intelligent carriers in diverse applications. copolymers 72-82 zinc finger C3HC-type containing 1 Homo sapiens 59-63 12809785-2 2003 The effect of the molecular weight of PEG and the copolymer ratio on the properties of the copolymers was investigated by (1)H-NMR, IR, DSC and GPC. copolymers 91-101 glycophorin C (Gerbich blood group) Homo sapiens 144-147 15089315-0 2004 Morphology and phase diagram of complex block copolymers: ABC linear triblock copolymers. copolymers 46-56 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 58-61 15503628-3 2004 The resulting copolymers were characterized using NMR spectroscopy and size-exclusion chromatography-multiangle light scattering (SEC-MALS). copolymers 14-24 natural cytotoxicity triggering receptor 3 Homo sapiens 134-138 14624516-2 2003 The copolymers were characterized with respect to their composition (NMR), thermal properties (DSC), and swelling. copolymers 4-14 desmocollin 3 Homo sapiens 95-98 12741775-1 2003 Differentially charged analogues of block copolymers containing repeating sequences from silk (GAGAGS) and elastin (GVGVP) were synthesized using genetic engineering techniques by replacing a valine residue with glutamic acid. copolymers 42-52 elastin Homo sapiens 107-114 16256531-0 2003 Alumina interaction with AMPS-MPEG random copolymers I. Adsorption and electrokinetic behavior. copolymers 42-52 adenylosuccinate lyase Homo sapiens 25-29 12866066-3 2003 The structures of the copolymers were characterized by (1)H and (31)P NMR spectroscopy and GPC measurements. copolymers 22-32 glycophorin C (Gerbich blood group) Homo sapiens 91-94 12538842-0 2003 Optimal structure requirements for pluronic block copolymers in modifying P-glycoprotein drug efflux transporter activity in bovine brain microvessel endothelial cells. copolymers 50-60 phosphoglycolate phosphatase Bos taurus 74-88 12689681-5 2003 We demonstrate that synthetic biodegradable polymers, poly-D,L-lactic acid-polyethylene glycol (PLA-PEG) block copolymers, which exhibit an exquisite temperature-dependent liquid-semisolid transition, work well as an injectable delivery system for recombinant human (rh) BMP-2. copolymers 111-121 bone morphogenetic protein 2 Homo sapiens 271-276 15348650-1 2002 Copolymers containing functional groups with activity as antiaggregating agents for platelets, based on random chains of metacryloyloxyethyl [2-(acetyloxy)-4-(trifluoromethyl)]benzoate, TH, and 2-acrylamido-2-metylpropanesulfonic acid, AMPS, with AMPS molar fractions ranging from 0.1 to 0.4, have been prepared. copolymers 0-10 adenylosuccinate lyase Homo sapiens 236-240 14870940-3 2003 The copolymers were characterized by 1H-NMR, 13C-NMR, FT-IR, GPC and DSC. copolymers 4-14 glycophorin C (Gerbich blood group) Homo sapiens 61-64 14870940-3 2003 The copolymers were characterized by 1H-NMR, 13C-NMR, FT-IR, GPC and DSC. copolymers 4-14 desmocollin 3 Homo sapiens 69-72 15348650-1 2002 Copolymers containing functional groups with activity as antiaggregating agents for platelets, based on random chains of metacryloyloxyethyl [2-(acetyloxy)-4-(trifluoromethyl)]benzoate, TH, and 2-acrylamido-2-metylpropanesulfonic acid, AMPS, with AMPS molar fractions ranging from 0.1 to 0.4, have been prepared. copolymers 0-10 adenylosuccinate lyase Homo sapiens 247-251 12384307-0 2002 Self-assembly of block copolymers derived from elastin-mimetic polypeptide sequences. copolymers 23-33 elastin Homo sapiens 47-54 12484491-0 2002 Synthesis and characterization of elastic PLGA/PCL/PLGA tri-block copolymers. copolymers 66-76 PHD finger protein 1 Homo sapiens 42-55 12009286-3 2002 Five of these novel block copolymers (K1-5), differing in the length of both the PEG chain and the linear charge density of the poly(dimethylamino)ethyl methacrylate block, were prepared and analyzed for gene delivery, gene expression and safety. copolymers 26-36 keratin 15 Homo sapiens 38-42 12442814-4 2002 The in vitro cytotoxicity of the copolymers was evaluated on EMT-6 mouse mammary tumor cells in comparison to Cremophor EL (CRM). copolymers 33-43 IL2 inducible T cell kinase Mus musculus 61-64 12070311-5 2002 Most importantly, these novel copolymers suppressed experimental autoimmune encephalomyelitis, induced in the susceptible SJL/J (H-2(s)) strain of mice with the encephalitogenic epitope PLP 139-151, more efficiently than did Cop 1. copolymers 30-40 proteolipid protein (myelin) 1 Mus musculus 186-189 12070311-5 2002 Most importantly, these novel copolymers suppressed experimental autoimmune encephalomyelitis, induced in the susceptible SJL/J (H-2(s)) strain of mice with the encephalitogenic epitope PLP 139-151, more efficiently than did Cop 1. copolymers 30-40 COP1, E3 ubiquitin ligase Mus musculus 225-230 11866567-7 2002 The enzymatic degradability of the graft copolymers, as evaluated with lysozyme, was also dependent on the grafting extent and much higher than that of the original chitin. copolymers 41-51 lysozyme Homo sapiens 71-79 12484491-4 2002 It was found that PLGA/PCL/PLGA copolymers with a MW of 10000 and lactide/glycolide ratios of 50/50 and 75/25 demonstrated desirable mechanical properties of elasticity (Young"s modulus 26.0 and 19.8 MPa) and showed controllable degradability over a 2-month period depending on the monomer composition. copolymers 32-42 PHD finger protein 1 Homo sapiens 23-26 11484938-7 2001 a-PHB oligomers with well-defined end groups, as well as respective block copolymers, can be prepared via regioselective ring-opening oligomerization of (R,S) beta-butyrolactone induced by amino acids under their zwitterionic form. copolymers 74-84 prohibitin 1 Homo sapiens 2-5 11783881-1 2001 Various quasi-one-dimensional superlattices (copolymers) (AmBn)x of two novel donor-acceptor polymers PPDCF ([A]x) and PPDCN ([B]x) based on poly(cyclopentadienylene) (PPD) and belonging to the class of type II staggered superlattices were investigated using a negative factor counting method in the tight-binding approximation. copolymers 45-55 ameloblastin Homo sapiens 58-62 11783881-3 2001 The trends in the electronic structures and conduction properties of the copolymers (AmBn)x as a function of the block sizes m and n, arrangement of the units (periodic or random) in the copolymer chain, and length of the copolymer chain are discussed. copolymers 73-83 ameloblastin Homo sapiens 85-89 15348254-1 2001 This paper presents the results of a preliminary screening of a new class of bioerodable polymers, partial esters of alternating copolymers of maleic anhydride and mono-methoxyoligoethyleneglycol vinyl ethers (PAM) for use in engineered vascular tissue. copolymers 129-139 peptidylglycine alpha-amidating monooxygenase Homo sapiens 210-213 11278034-0 2001 Thermoprecipitation of lysozyme from egg white using copolymers of N-isopropylacrylamide and acidic monomers. copolymers 53-63 lysozyme Homo sapiens 23-31 11278034-1 2001 Thermoprecipitation of lysozyme from egg white was demonstrated using copolymers of N-isopropylacrylamide with acrylic acid, methacrylic acid, 2-acryloylamido-2-methylpropane-sulfonic acid and itaconic acid, respectively. copolymers 70-80 lysozyme Homo sapiens 23-31 11389623-2 2001 Their interior was functionalized by a "ship in bottle" synthesis of copolymers. copolymers 69-79 inositol polyphosphate-5-phosphatase D Homo sapiens 40-44 11278034-8 2001 Thermoprecipitation using these copolymers, which enables very high recovery of lysozyme from egg white, would be advantageous over pH sensitive polymers, which generally exhibit lower recovery. copolymers 32-42 lysozyme Homo sapiens 80-88 11749177-4 2001 Copolymers bpy(PCL-PLA)(2) and bpy(PLA-PCL)(2) were generated in an analogous manner using bpyPLA(2) and bpyPCL(2) as macroinitiators. copolymers 0-10 PHD finger protein 1 Homo sapiens 15-18 11197495-2 2001 Our main hypothesis is that the bioerodible copolymer poly(1,6-bis-p-carboxyphenoxyhexane-co-sebacic anhydride) (CPH : SA) undergoes micro-phase separation at certain copolymer compositions due to differences in relative hydrophobicity of the co-monomers, resulting in thermodynamic partitioning of drugs incorporated into these copolymers. copolymers 329-339 carboxypeptidase E Homo sapiens 113-116 10814588-1 2000 Triblock copolymers of the form PEO(alpha)PPO(beta)PEO(alpha) [where PEO is poly(ethylene oxide) and PPO is poly(propylene oxide)] have many biomedical applications, many of which depend on the surface properties of the copolymers and the influence that those properties have on the adsorption of proteins. copolymers 9-19 protoporphyrinogen oxidase Homo sapiens 42-45 11710132-3 2000 Four different copolymers of n-butyl methacrylate (BMA) and hexa(ethylene glycol) methacrylate (HEGMA) were prepared and characterized. copolymers 15-25 hexosaminidase subunit alpha Homo sapiens 60-102 11113279-8 2000 Since these sulfated copolymers inhibit both thrombin [4] and plasmin activity, they may be a useful therapeutic tool in situations when both the blood coagulation and the fibrinolytic system are activated (such as intravascular coagulation and fibrinolysis, ICF). copolymers 21-31 coagulation factor II, thrombin Homo sapiens 45-53 11113279-8 2000 Since these sulfated copolymers inhibit both thrombin [4] and plasmin activity, they may be a useful therapeutic tool in situations when both the blood coagulation and the fibrinolytic system are activated (such as intravascular coagulation and fibrinolysis, ICF). copolymers 21-31 plasminogen Homo sapiens 62-69 10814588-1 2000 Triblock copolymers of the form PEO(alpha)PPO(beta)PEO(alpha) [where PEO is poly(ethylene oxide) and PPO is poly(propylene oxide)] have many biomedical applications, many of which depend on the surface properties of the copolymers and the influence that those properties have on the adsorption of proteins. copolymers 9-19 protoporphyrinogen oxidase Homo sapiens 101-104 10814588-4 2000 Beads coated with condensed films of copolymers that contain short PEO segments and elicit appreciable inflammation absorb appreciable quantities of plasma proteins, including fibrinogen, from aqueous solution. copolymers 37-47 fibrinogen beta chain Homo sapiens 176-186 10814588-8 2000 In this regard, the ability of the copolymers to influence fibrinogen-mediated adhesive events may be particularly important. copolymers 35-45 fibrinogen beta chain Homo sapiens 59-69 10814588-9 2000 As to the mechanism of protein resistance, our data support the proposal that sibling PEO segments of copolymers in condensed films fold back across their parental PPO cores, limiting access of proteins to the hydrophobic cores themselves. copolymers 102-112 protoporphyrinogen oxidase Homo sapiens 164-167 10767594-0 2000 Physicochemical and biological characterisation of an antisense oligonucleotide targeted against the bcl-2 mRNA complexed with cationic-hydrophilic copolymers. copolymers 148-158 B cell leukemia/lymphoma 2 Mus musculus 101-106 10820481-0 2000 Silole-Thiophene Alternating Copolymers with Narrow Band Gaps This work was partly supported by a Grant-in-Aid (No. copolymers 29-39 activation induced cytidine deaminase Homo sapiens 107-110 10767594-1 2000 The aim of this study was to evaluate the use of cationic-hydrophilic copolymers for self-assembly with antisense oligonucleotides targeted to the bcl-2 mRNA in order to improve their biocompatibility and modulation of their pharmacokinetics for greater therapeutic usefulness. copolymers 70-80 B cell leukemia/lymphoma 2 Mus musculus 147-152 10220856-1 1999 alpha-Methylstyrene (AMS) is a chemical intermediate used in the synthesis of specialty polymers and copolymers. copolymers 101-111 methionine adenosyltransferase I, alpha Mus musculus 21-24 10767140-1 2000 The solubilization of five hydrophilic water-soluble aroma compounds in self-aggregating triblock amphiphilic copolymers of poly(ethylene oxide)-poly(propylene oxide)-poly(ethylene oxide) (PEO-PPO-PEO), with similar percentages of PEO and different molecular weights, was studied. copolymers 110-120 protoporphyrinogen oxidase Homo sapiens 193-196 10879180-3 2000 We synthesized PLEG copolymers containing PEG segments with various molecular weight and prepared hCG-loaded PL/PLEG blend microspheres to improve hCG entrapment efficiency. copolymers 20-30 hypertrichosis 2 (generalised, congenital) Homo sapiens 98-101 10640641-7 2000 When PEO/PLLA multiblock copolymers were applied as a wound healing material loaded with basic fibroblast growth factor (bFGF), the feasibility study showed improved wound healing when compared to controls of no treatment and the same wound covering without bFGF, indicating that a certain degree of the bioactivity of bFGF is preserved. copolymers 25-35 fibroblast growth factor 2 Homo sapiens 89-119 10640641-7 2000 When PEO/PLLA multiblock copolymers were applied as a wound healing material loaded with basic fibroblast growth factor (bFGF), the feasibility study showed improved wound healing when compared to controls of no treatment and the same wound covering without bFGF, indicating that a certain degree of the bioactivity of bFGF is preserved. copolymers 25-35 fibroblast growth factor 2 Homo sapiens 121-125 10640641-7 2000 When PEO/PLLA multiblock copolymers were applied as a wound healing material loaded with basic fibroblast growth factor (bFGF), the feasibility study showed improved wound healing when compared to controls of no treatment and the same wound covering without bFGF, indicating that a certain degree of the bioactivity of bFGF is preserved. copolymers 25-35 fibroblast growth factor 2 Homo sapiens 258-262 10640641-7 2000 When PEO/PLLA multiblock copolymers were applied as a wound healing material loaded with basic fibroblast growth factor (bFGF), the feasibility study showed improved wound healing when compared to controls of no treatment and the same wound covering without bFGF, indicating that a certain degree of the bioactivity of bFGF is preserved. copolymers 25-35 fibroblast growth factor 2 Homo sapiens 258-262 10640656-8 2000 For films prepared from block copolymers with PEG blocks of 4000 g/mol, first-order lysozyme release was observed. copolymers 30-40 lysozyme Homo sapiens 84-92 10469910-14 1999 Random 1:1 copolymers of ethyl acrylate (EA) and acrylic acid (AAc) (which contain random -COOH and -C(2)H(5) groups that are present and regularly repeat in PEAAc) also displayed significant hemolytic activity, with an efficiency close to PEAAc. copolymers 11-21 glycine-N-acyltransferase Homo sapiens 63-66 10357135-15 1999 The results of the present study indicate that PLG copolymers are good carriers for BMP and promote the induction of new bone formation. copolymers 51-61 plasminogen Homo sapiens 47-50 10357135-16 1999 Further, the PLG copolymers with rhBMP-2 had a greater effect in inducing new bone formation and resorbing the implanted material than active DFDBA alone. copolymers 17-27 plasminogen Homo sapiens 13-16 10332063-4 1999 In the case of the linear block copolymers, a reduced lactic acid content in a linear block copolymer yielded smaller particles, a lower encapsulation efficiency, and a higher initial drug release both in the case of EPO and FITC-dextran. copolymers 32-42 erythropoietin Homo sapiens 217-220 10330269-0 1999 Binding of random copolymers of three amino acids to class II MHC molecules. copolymers 18-28 major histocompatibility complex, class I, C Homo sapiens 62-65 10330269-3 1999 In the present study the binding of copolymers composed of three of the four amino acids found in poly(Y,E,A,K) to purified class II MHC molecules was examined. copolymers 36-46 major histocompatibility complex, class I, C Homo sapiens 133-136 15348037-0 2000 Hydrolytic degradation of PCL/PEO copolymers in alkaline media. copolymers 34-44 twinkle mtDNA helicase Homo sapiens 30-33 15348037-4 2000 The results showed that the presence of PEO sequences considerably enhanced the hydrophilicity of the copolymers as compared with PCL homopolymer. copolymers 102-112 twinkle mtDNA helicase Homo sapiens 40-43 15348137-1 1999 Synthetic copolymers poly(epsilon-caprolactone-co-vinylphosphonic acid) (P(MDOVPA) and poly(epsilon-caprolactone-co-dimethylvinylphosphoester) (P(MDOVPE)) were used to prepare composites with polylactide (PLac) and hydroxyapatite (HAp). copolymers 10-20 reticulon 3 Homo sapiens 231-234 10210724-2 1999 The materials characterization, enzymatic degradability and peptide (insulin) release from solutions of the copolymers were examined. copolymers 108-118 insulin Homo sapiens 69-76 10210724-8 1999 Leakage of insulin from the copolymers was dependent upon the PEG content. copolymers 28-38 insulin Homo sapiens 11-18 10213370-0 1999 Inhibition of multidrug resistance-associated protein (MRP) functional activity with pluronic block copolymers. copolymers 100-110 ATP binding cassette subfamily C member 3 Homo sapiens 14-53 10213370-0 1999 Inhibition of multidrug resistance-associated protein (MRP) functional activity with pluronic block copolymers. copolymers 100-110 ATP binding cassette subfamily C member 3 Homo sapiens 55-58 10213370-6 1999 CONCLUSIONS: This paper demonstrates for the first time that Pluronic block copolymers inhibit multidrug resistance-associated protein (MRP). copolymers 76-86 ATP binding cassette subfamily C member 3 Homo sapiens 95-134 10213370-6 1999 CONCLUSIONS: This paper demonstrates for the first time that Pluronic block copolymers inhibit multidrug resistance-associated protein (MRP). copolymers 76-86 ATP binding cassette subfamily C member 3 Homo sapiens 136-139 10213370-7 1999 The similarities in the effects of Pluronic block copolymers on MRP and P-glycoprotein drug efflux systems suggest that a single unifying mechanism may explain the inhibition observed. copolymers 50-60 ATP binding cassette subfamily C member 3 Homo sapiens 64-67 10070266-4 1999 Binding isotherms were obtained for beta-lactoglobulin and for bovine serum albumin interacting with a series of alternating copolymers of maleic acid and alkyl-vinyl ethers of varying hydrophobicity. copolymers 125-135 albumin Homo sapiens 70-83 9885264-4 1999 It shows that the relative intensities of several peaks in Raman spectra are dependent on the PPO/PEO ratios and the conformation of the copolymers. copolymers 137-147 protoporphyrinogen oxidase Homo sapiens 94-97 9885264-6 1999 Other block copolymers exhibit that the disordered structure increases with increasing PPO/PEO ratio. copolymers 12-22 protoporphyrinogen oxidase Homo sapiens 87-90 9833994-2 1998 METHODS: The block copolymers" PEO-PBLA-Pyrene was first synthesized by reacting with pyrene sulfonyl chloride and PEO-PBLA in tetrahydrofuran (THF) solution and were identified by GPC reflect index, UV and fluorescence detectors. copolymers 19-29 glycophorin C (Gerbich blood group) Homo sapiens 181-184 9741918-1 1998 Sequential block copolymers consisting of tandem repetition of amino acids have been constructed and genetically produced based on the natural repeating structures of silk and elastin protein. copolymers 17-27 elastin Homo sapiens 176-183 9766248-6 1998 GPC measurement of the microcapsules revealed that the copolymers were degraded during the incubation. copolymers 55-65 glycophorin C (Gerbich blood group) Homo sapiens 0-3 9770519-3 1998 In the present study, YEAK and YEAK-related copolymers and type II collagen (CII) peptide 261-273, a candidate autoantigen in rheumatoid arthritis (RA), competed for binding to RA-associated HLA-DR molecules encoded by DRB1*0101 and DRB1*0401. copolymers 44-54 major histocompatibility complex, class II, DR beta 1 Homo sapiens 219-223 9770519-3 1998 In the present study, YEAK and YEAK-related copolymers and type II collagen (CII) peptide 261-273, a candidate autoantigen in rheumatoid arthritis (RA), competed for binding to RA-associated HLA-DR molecules encoded by DRB1*0101 and DRB1*0401. copolymers 44-54 major histocompatibility complex, class II, DR beta 1 Homo sapiens 233-237 9770519-4 1998 Moreover, these copolymers (particularly YEAK, YAK, and YEK) inhibited the response of DR1- and DR4-restricted T cell clones to the CII epitope 261-273 by >50%. copolymers 16-26 down-regulator of transcription 1 Homo sapiens 87-90 9770519-4 1998 Moreover, these copolymers (particularly YEAK, YAK, and YEK) inhibited the response of DR1- and DR4-restricted T cell clones to the CII epitope 261-273 by >50%. copolymers 16-26 major histocompatibility complex, class II, DR beta 4 Homo sapiens 96-99 9545428-6 1998 Specific copolymers were found to sterically stabilize red blood cells from lectin-induced hemagglutination and fibroblasts from adhesion to fibronectin-coated surfaces. copolymers 9-19 fibronectin 1 Homo sapiens 141-152 9358444-1 1997 A series of linear copolymers of DTPA-class Gd3+ conjugates, linked by alpha, omega-alkyldiamides with a varying number (n) of methylenes separating the amide function, were synthesized. copolymers 19-29 GRDX Homo sapiens 44-47 8612790-2 1996 In contrast, the ATPase activation of the copolymers was decreased when supplemented with tropomyosin. copolymers 42-52 dynein axonemal heavy chain 8 Homo sapiens 17-23 8921953-2 1996 Here we report that a selected adjuvant comprising block copolymers in a water-in-oil emulsion can induce balanced TH1/TH2 responses in BALB/c mice primed at 1 week of age with an immunodominant tetanus peptide vaccine. copolymers 57-67 negative elongation factor complex member C/D, Th1l Mus musculus 115-118 8921953-2 1996 Here we report that a selected adjuvant comprising block copolymers in a water-in-oil emulsion can induce balanced TH1/TH2 responses in BALB/c mice primed at 1 week of age with an immunodominant tetanus peptide vaccine. copolymers 57-67 heart and neural crest derivatives expressed 2 Mus musculus 119-122 8818545-4 1996 Mice implanted with these copolymers were effectively protected against lethal wasting and from arthritis resulting from chronic exposure to TNF. copolymers 26-36 tumor necrosis factor Mus musculus 141-144 9201989-11 1997 An excimer peak was present in the emission spectrum of labeled S265C F-actin and in the labeled S265C/C374A-WT actin copolymers. copolymers 118-128 actin Saccharomyces cerevisiae S288C 112-117 8731216-0 1996 Conjugates of insulin with copolymers of N-(2-hydroxypropyl) methacrylamide: effects on smooth muscle cell proliferation. copolymers 27-37 insulin Homo sapiens 14-21 8198203-4 1994 We have previously shown that synthetic copolymers of L-amino acids, GT and GAT, are powerful tools for clarifying the role of regulatory T-cells in both cell-mediated and humoral immunity in inbred mouse strains. copolymers 40-50 glycine-N-acyltransferase Mus musculus 76-79 7588715-8 1995 As such, it could form cross-linked copolymers with the extracellular matrix protein, laminin, making it all the more likely that pp-vWF plays a role in cell adhesion phenomena [Takagi, J., Sudo, Y., Saito, T. & Saito, Y. copolymers 36-46 von Willebrand factor Bos taurus 133-136 7711033-3 1995 The condensation of the alternating copolymers by TP2 (incubated with 10 microM ZnSO4), namely, poly(dG-dC).poly(dG-dC) and poly(dA-dT).poly(dA-dT), was severalfold higher than condensation of either of the homoduplexes poly(dG).poly-(dC) and poly(dA).poly(dT) or rat oligonucleosomal DNA. copolymers 36-46 transition protein 2 Rattus norvegicus 50-53 1457677-5 1992 They confirmed that the hydrophilic polyoxyethylene steric layer, created by coating with the block copolymers, reduced the adsorption of human serum albumin. copolymers 100-110 albumin Homo sapiens 150-157 1420910-9 1992 The sliding velocities of actin over copolymers of modified and unmodified myosins in the motility assay were slowest with rigor-modified myosin and most rapid with SH2-labeled myosin. copolymers 37-47 myosin heavy chain 14 Homo sapiens 75-81 1420910-9 1992 The sliding velocities of actin over copolymers of modified and unmodified myosins in the motility assay were slowest with rigor-modified myosin and most rapid with SH2-labeled myosin. copolymers 37-47 myosin heavy chain 14 Homo sapiens 138-144 1319582-7 1992 The temperature dependence of ACTH release paralleled that of ionophore activity measured in red blood cells, providing evidence that the ability to induce ACTH is related to the ionophore property of the copolymers. copolymers 205-215 pro-opiomelanocortin-alpha Mus musculus 30-34 1319582-7 1992 The temperature dependence of ACTH release paralleled that of ionophore activity measured in red blood cells, providing evidence that the ability to induce ACTH is related to the ionophore property of the copolymers. copolymers 205-215 pro-opiomelanocortin-alpha Mus musculus 156-160 1319582-10 1992 These data support an ionophore mechanism for copolymer-induced ACTH release in which changes in the physicochemical structure of the copolymers may affect their interaction with cell membranes. copolymers 134-144 pro-opiomelanocortin-alpha Mus musculus 64-68 1457677-1 1992 The adsorption of human serum albumin to polystyrene microspheres sterically stabilized with block copolymers, was investigated using photon correlation spectroscopy and laser doppler anenometry. copolymers 99-109 albumin Homo sapiens 30-37 1567419-1 1992 L-Asparaginase from Escherichia coli, an anti-tumor enzyme, was chemically modified with two types of maleic anhydride copolymers with a comb-shaped form, the one composed of polyoxyethylene allyl methyl diether with the molecular weight of 13,000 (activated PM13) and the other of polyoxyethylene 2-methyl-2-propenyl methyl diether with 100,000 (activated PM100). copolymers 119-129 asparaginase and isoaspartyl peptidase 1 Homo sapiens 0-14 1457677-6 1992 Moreover, the amount of human serum albumin adsorbed was related to the polyoxyethylene content of the block copolymers. copolymers 109-119 albumin Homo sapiens 36-43 2058267-6 1991 The smaller older copolymers, L101 and L121, induced higher absolute levels of IgG3 antibody and relative increases in IgG1. copolymers 18-28 Immunoglobulin heavy constant gamma 3 Mus musculus 79-83 1761373-1 1991 Copolymers of acrylated derivatives of alpha-chymotrypsin and polyethylene glycol (PEG) have been prepared and used as biocatalysts for the synthesis of model peptides in organic solvent containing a low quantity of water. copolymers 0-10 progestagen associated endometrial protein Homo sapiens 62-87 2058267-6 1991 The smaller older copolymers, L101 and L121, induced higher absolute levels of IgG3 antibody and relative increases in IgG1. copolymers 18-28 LOC105243590 Mus musculus 119-123 2119384-4 1990 The epoxy- and isocyanate-activated grafted copolymers were used for the affinity chromatographic separation of insulin, factor VIII and human serum albumin using antibodies as affinity ligands. copolymers 44-54 insulin Homo sapiens 112-119 2271656-3 1990 Escherichia coli endonuclease III was used to quantitate the formation and stability of these hydrates in the double-stranded alternating copolymers poly(dG-dC) and poly(dA-dU). copolymers 138-148 endonuclease III Escherichia coli 17-33 2252649-4 1990 Photoreactive, hydrophilic copolymers with poly(dimethyl acrylamide) and albumin, both of which were chemically fixed on surfaces, were found effective for blood compatible surfaces; a fibronectin-bound surface was suitable for providing tissue compatibility. copolymers 27-37 fibronectin 1 Homo sapiens 185-196 33809286-9 2021 Chemical structures of the copolymers were confirmed by attenuated total reflection-Fourier transform infrared (ATR/FT-IR) spectroscopy. copolymers 27-37 ATR serine/threonine kinase Homo sapiens 112-115 1366613-7 1990 Additionally, we have produced alternating block copolymers of various amounts of silk-like and elastin-like blocks, ranging from a ratio of 1:4 to 2:1, respectively. copolymers 49-59 elastin Homo sapiens 96-103 33807821-9 2021 The improvement of the electrochemical properties is attributed to the introduction of the SPB block into the block copolymers. copolymers 116-126 surfactant protein B Homo sapiens 91-94 34638747-7 2021 The molecular weights, polydispersities and grafting efficiencies of azido molecules of these copolymers were investigated by NMR and GPC. copolymers 94-104 glycophorin C (Gerbich blood group) Homo sapiens 134-137 19138732-1 2009 The diffusion mechanism of vitamin B12 in two types of crosslinked hydrogels, poly(acrylic acid) (cPAA) and copolymers of acrylic acid and N-vinyl pyrrolidinone (cP(AA-NVP)) was studied. copolymers 108-118 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 35-38 19138732-3 2009 In the copolymers permeability of B12 is controlled by both intramolecular and intermolecular hydrogen-bonding between the pyrrolidinone and carboxylic acid side chains. copolymers 7-17 NADH:ubiquinone oxidoreductase subunit B3 Homo sapiens 34-37 34797674-1 2021 The assembly/disassembly of star block copolymers induced by changes in temperature or pH of the medium is anticipated to have interesting implications for hosting/releasing drugs and tuning chemical reactions. copolymers 39-49 steroidogenic acute regulatory protein Homo sapiens 28-32 34830139-2 2021 The prepared copolymers and the macroinitiator were characterized by NMR, GPC, AFM, turbidimetry, static, and dynamic light scattering. copolymers 13-23 glycophorin C (Gerbich blood group) Homo sapiens 74-77 34738689-1 2021 ABC triblock copolymers composed of hydrophobic poly(epsilon-caprolactone) (PCL), zwitterionic poly(carboxybetaine methacrylate) (PCBMA) midblock, and P(PEGMA-UPy0.15 ) containing supramolecular ureidopyrimidinone moieties, PCL-b-PCBMA-b-P(PEGMA-UPy0.15 ), were investigated to achieve multifunctional antifreeze hydrogels. copolymers 13-23 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 0-3 34685279-3 2021 The copolymers were prepared via emulsion copolymerization technique and the products were isolated and characterized by means of structure identity, thermal behavior (DSC and DMTA), coating performance. copolymers 4-14 desmocollin 3 Homo sapiens 168-171 34242455-0 2021 Intramolecular Folding of Coil-Helix Block Copolymers Induced by Quadrupole Interactions. copolymers 43-53 coilin Homo sapiens 26-30 34242455-5 2021 The folding behavior of the coil-helix block copolymers is investigated by dynamic light scattering (DLS), NMR spectroscopy, wide-angle X-ray scattering (WAXS), and differential scanning calorimetry (DSC). copolymers 45-55 coilin Homo sapiens 28-32 34590464-4 2021 The resultant copolymers and their intermediates were characterized using 1H nuclear magnetic resonance and GPC. copolymers 14-24 glycophorin C (Gerbich blood group) Homo sapiens 108-111 33232430-1 2021 The phase behavior of non-frustrated ABC block copolymers polymers, modeling poly(isoprene-b-styrene-b-ethylene oxide) (ISO), is studied using dissipative particle dynamic (DPD) simulations. copolymers 47-57 ATP binding cassette subfamily B member 6 (Langereis blood group) Homo sapiens 37-40 34883118-7 2022 Conformational analysis by CD and FT-IR revealed that the SMA copolymers modulate the conformation of amylin aggregates. copolymers 62-72 islet amyloid polypeptide Homo sapiens 102-108 34883118-11 2022 Toxicity analysis showed both SMA copolymers to be non-toxic in vitro and the amylin species formed with the copolymers showed minimal deformity to zebrafish embryos. copolymers 109-119 islet amyloid polypeptide Homo sapiens 78-84 34883118-12 2022 Together, this study demonstrates that chemical tools, such as copolymers, can be used to modulate amylin aggregation, alter the conformation of species. copolymers 63-73 islet amyloid polypeptide Homo sapiens 99-105 34826745-1 2022 Pluronic (PEO-PPO-PEO) block copolymers can form nano-sized micelles with a structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. copolymers 29-39 protoporphyrinogen oxidase Homo sapiens 14-17 34826745-1 2022 Pluronic (PEO-PPO-PEO) block copolymers can form nano-sized micelles with a structure composed of a hydrophobic PPO core and hydrophilic PEO shell layer. copolymers 29-39 protoporphyrinogen oxidase Homo sapiens 112-115 34751988-3 2021 The terpolymerization took place in a sequence-controlled fashion, affording unique multi-block copolymers composed of two different ethylene-alt-methoxyarylpropylene sequences E-alt-AR1 P (soft segments) and E-alt-AR2 P (hard segments) and relatively short ethylene-ethylene (EE) blocks (crystalline segments). copolymers 96-106 transcription factor 20 Homo sapiens 183-186 34771233-9 2021 To further demonstrate the highly effective new trithiocarbonate end-functionality, the PNVCL polymers were successfully chain extended with N-isopropylacrylamide (NIPAM) to form six-arm star-shaped PNIPAM-b-PNVCL block copolymers. copolymers 220-230 steroidogenic acute regulatory protein Homo sapiens 187-191 34206141-1 2021 The interaction of multi-LacNAc (Galbeta1-4GlcNAc)-containing N-(2-hydroxypropyl) methacrylamide (HPMA) copolymers with human galectin-1 (Gal-1) and the carbohydrate recognition domain (CRD) of human galectin-3 (Gal-3) was analyzed using NMR methods in addition to cryo-electron-microscopy and dynamic light scattering (DLS) experiments. copolymers 104-114 galectin 1 Homo sapiens 126-136 34213889-5 2021 These copolymers demonstrate promise as simple formulation additives to increase the cold chain resilience of commercial insulin formulations, thereby expanding global access to these critical drugs for treatment of diabetes. copolymers 6-16 insulin Homo sapiens 121-128 34234415-3 2021 Methods: Folate-conjugated beta-CD-polycaprolactone block copolymers were synthesized and characterized. copolymers 58-68 ACD shelterin complex subunit and telomerase recruitment factor Homo sapiens 27-34 34371363-0 2021 Fast and efficient single step liquid chromatography separation of parent homopolymers from block copolymers. copolymers 98-108 Fas activated serine/threonine kinase Homo sapiens 0-4 34502954-2 2021 In this study, through Suzuki coupling polymerization, three 1,4-naphthalene-based copolymers-namely, PNP(1,4)-PT, PNP(1,4)-TF, and PNP(1,4)-ANT-were designed and synthesized. copolymers 83-93 protein tyrosine phosphatase non-receptor type 13 Homo sapiens 132-139 34451284-7 2021 The enhanced permeability results from the increases in both sorption coefficient and gas diffusivity of copolymers. copolymers 105-115 gastrin Homo sapiens 86-89 34443448-3 2021 The obtained copolymers were characterized by 1H-NMR, GPC and ESI-MS, respectively in order to confirm their chemical structures and identity. copolymers 13-23 glycophorin C (Gerbich blood group) Homo sapiens 54-57 34145658-1 2021 A dithiocarbamate chain transfer agent (CTA) based on Z-group substituted with a diphenyl amine (-NPh2 ) moiety is selected for the synthesis of statistical and diblock copolymers of ethylene and vinyl acetate via reversible addition-fragmentation chain transfer polymerization. copolymers 169-179 neurexophilin 2 Homo sapiens 98-102 34206141-1 2021 The interaction of multi-LacNAc (Galbeta1-4GlcNAc)-containing N-(2-hydroxypropyl) methacrylamide (HPMA) copolymers with human galectin-1 (Gal-1) and the carbohydrate recognition domain (CRD) of human galectin-3 (Gal-3) was analyzed using NMR methods in addition to cryo-electron-microscopy and dynamic light scattering (DLS) experiments. copolymers 104-114 galectin 1 Homo sapiens 138-143 35394757-6 2022 All synthesized copolymers showed excellent CXCR4-binding and inhibiting ability in vitro and improved cellular uptake in hypoxia-reoxygenation stimulated mouse tubule cells. copolymers 16-26 chemokine (C-X-C motif) receptor 4 Mus musculus 44-49 35487349-5 2022 Structural isomers were also observed for C4- and C8-FASA-based copolymers. copolymers 64-74 FASA Homo sapiens 53-57 35570405-6 2022 This strategy opens new avenues in designing GF-binding copolymers as synthetic mimics of fibronectin for diverse applications. copolymers 56-66 fibronectin 1 Homo sapiens 90-101 34064416-4 2021 The synthesized copolymers were characterized using 1H NMR, GPC, FTIR, XRD, and DSC. copolymers 16-26 glycophorin C (Gerbich blood group) Homo sapiens 60-63 35378474-2 2022 Herein, two organic copolymers with nanorod-like morphology (AN-TA, and AN-PA), composed of different tertiary amines, are synthesized as the cathode material for an aqueous proton battery. copolymers 20-30 natriuretic peptide receptor 1 Homo sapiens 72-77 35378474-4 2022 Among the two copolymers, AN-PA exhibits the maximum specific capacity of 145 mAh g-1 at 1 A g-1 and then, even at the higher current density of 10 A g-1, it possesses the capacity as 110 mAh g-1 in 2 M HCl. copolymers 14-24 natriuretic peptide receptor 1 Homo sapiens 26-31 35526106-6 2022 We believe POx block copolymers can be used as a semi-ubiquitous stabilizer for the rapid development of nanocrystal formulations for new and existing diseases. copolymers 21-31 proline dehydrogenase 1 Homo sapiens 11-14 34978757-0 2022 Hyperproduction of PHA copolymers containing high fractions of 4-hydroxybutyrate (4HB) by outer membrane-defected Halomonas bluephagenesis grown in bioreactors. copolymers 23-33 lamin B receptor Homo sapiens 19-22 35566865-0 2022 A Study on the Dual Thermo- and pH-Responsive Behaviors of Well-Defined Star-like Block Copolymers Synthesize by Combining of RAFT Polymerization and Thiol-Ene Click Reaction. copolymers 88-98 steroidogenic acute regulatory protein Homo sapiens 72-76 35566244-5 2022 The data obtained from the EDX analysis of the novel cross-linked copolymers confirmed the functionalization with aminobenzoic groups through the presence and content of nitrogen, as follows: PAB1: N% = 0.47; PAB2: N% = 0.85; and PAB3: N% = 1.30. copolymers 66-76 poly(A) binding protein cytoplasmic 1 pseudogene 10 Homo sapiens 192-196 35566865-1 2022 A series of stimuli-responsive star-like block copolymers are synthesized via the combination of reversible addition, fragmentation chain transfer (RAFT) polymerization, and photo-initiated thiol-ene (PITE) click reaction. copolymers 47-57 steroidogenic acute regulatory protein Homo sapiens 31-35 35566865-7 2022 The star-like block copolymers with well-defined structure and tunable composition, especially the facile-controlled block sequence, bring us a challenging opportunity to control the stimuli-responsive properties of star-like block copolymers. copolymers 20-30 steroidogenic acute regulatory protein Homo sapiens 4-8 35566865-2 2022 The controllable block ratio and block sequence, narrow distribution of molecular weight, and customized arm numbers of the star-shaped copolymers reveal the feasibility and benefits of combination of RAFT polymerization and PITE click reaction for synthesis of well-defined star-like (co)polymers. copolymers 136-146 steroidogenic acute regulatory protein Homo sapiens 124-128 35566865-7 2022 The star-like block copolymers with well-defined structure and tunable composition, especially the facile-controlled block sequence, bring us a challenging opportunity to control the stimuli-responsive properties of star-like block copolymers. copolymers 20-30 steroidogenic acute regulatory protein Homo sapiens 216-220 35566865-7 2022 The star-like block copolymers with well-defined structure and tunable composition, especially the facile-controlled block sequence, bring us a challenging opportunity to control the stimuli-responsive properties of star-like block copolymers. copolymers 232-242 steroidogenic acute regulatory protein Homo sapiens 4-8 35566865-2 2022 The controllable block ratio and block sequence, narrow distribution of molecular weight, and customized arm numbers of the star-shaped copolymers reveal the feasibility and benefits of combination of RAFT polymerization and PITE click reaction for synthesis of well-defined star-like (co)polymers. copolymers 136-146 steroidogenic acute regulatory protein Homo sapiens 275-279 35566865-7 2022 The star-like block copolymers with well-defined structure and tunable composition, especially the facile-controlled block sequence, bring us a challenging opportunity to control the stimuli-responsive properties of star-like block copolymers. copolymers 232-242 steroidogenic acute regulatory protein Homo sapiens 216-220 35566805-5 2022 The synthesized copolymers were characterized using 1H NMR, GPC, FTIR, XRD, and DSC. copolymers 16-26 glycophorin C (Gerbich blood group) Homo sapiens 60-63 35566805-5 2022 The synthesized copolymers were characterized using 1H NMR, GPC, FTIR, XRD, and DSC. copolymers 16-26 desmocollin 3 Homo sapiens 80-83 35350312-1 2022 Well-defined six-arm star-branched bio-degradable block copolymers of l-lactide and epsilon-caprolactone were prepared using controlled ring-opening polymerization and a sequential monomer addition method using dipentaerythritol as the initiator core and organocatalysts at low temperatures in solution. copolymers 56-66 steroidogenic acute regulatory protein Homo sapiens 21-25 35040533-3 2022 The copolymers show good solubility in common organic solvents, broad absorption in the visible spectral region from 300 nm to 700 nm, and deeper HOMO levels of -5.45 and -5.34 eV for P130 and P131, respectively. copolymers 4-14 nucleolar and coiled-body phosphoprotein 1 Homo sapiens 184-188 35575368-4 2022 Successful formation of the block copolymers is confirmed by 1H NMR, FT-IR, GPC, and DSC investigations. copolymers 34-44 glycophorin C (Gerbich blood group) Homo sapiens 76-79 35575368-4 2022 Successful formation of the block copolymers is confirmed by 1H NMR, FT-IR, GPC, and DSC investigations. copolymers 34-44 desmocollin 3 Homo sapiens 85-88 35160621-6 2022 The structure of synthesized copolymers was studied by FTIR, 1H-NMR, Soxhlet extraction, and molecular weight analyses by GPC. copolymers 29-39 glycophorin C (Gerbich blood group) Homo sapiens 122-125 35090961-7 2022 More specifically, the PCL is coupled with polyethylene glycol (PEG) to obtain amphiphilic thermosensitive "smart" copolymers (PCL-PEG), to form rapid and reversible physical gelation behavior. copolymers 115-125 PHD finger protein 1 Homo sapiens 23-26 35090961-7 2022 More specifically, the PCL is coupled with polyethylene glycol (PEG) to obtain amphiphilic thermosensitive "smart" copolymers (PCL-PEG), to form rapid and reversible physical gelation behavior. copolymers 115-125 PHD finger protein 1 Homo sapiens 127-130 35232958-0 2022 Pick up and dispose of pollutants from water via temperature-responsive micellar copolymers on magnetite nanorobots. copolymers 81-91 protein interacting with PRKCA 1 Homo sapiens 0-4 35215686-0 2022 Self-Assembled Amphiphilic Fluorinated Random Copolymers for the Encapsulation and Release of the Hydrophobic Combretastatin A-4 Drug. copolymers 46-56 carbonic anhydrase 4 Mus musculus 110-128 35054660-6 2022 The copolymers were characterized by 1H and 13C NMR, GPC, and FTIR methods. copolymers 4-14 glycophorin C (Gerbich blood group) Homo sapiens 53-56