PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 20837678-6 2010 In a multiplexed LXR-cofactor peptide interaction assay, 5,6-EC induced the recruitment of a number of cofactor peptides onto both LXRalpha and LXRbeta and showed an EC(50) of approximately 2 muM in peptide recruitment. 5,6-epoxycholesterol 57-63 nuclear receptor subfamily 1 group H member 3 Homo sapiens 131-139 20837678-6 2010 In a multiplexed LXR-cofactor peptide interaction assay, 5,6-EC induced the recruitment of a number of cofactor peptides onto both LXRalpha and LXRbeta and showed an EC(50) of approximately 2 muM in peptide recruitment. 5,6-epoxycholesterol 57-63 nuclear receptor subfamily 1 group H member 2 Homo sapiens 144-151 20837678-6 2010 In a multiplexed LXR-cofactor peptide interaction assay, 5,6-EC induced the recruitment of a number of cofactor peptides onto both LXRalpha and LXRbeta and showed an EC(50) of approximately 2 muM in peptide recruitment. 5,6-epoxycholesterol 57-63 latexin Homo sapiens 192-195 20837678-7 2010 Furthermore, 5,6-EC bound to LXRalpha in a radiolabeled ligand displacement assay (EC(50) = 76 nM), thus demonstrating it to be one of the most potent natural LXRalpha ligands known to date. 5,6-epoxycholesterol 13-19 nuclear receptor subfamily 1 group H member 3 Homo sapiens 29-37 20837678-7 2010 Furthermore, 5,6-EC bound to LXRalpha in a radiolabeled ligand displacement assay (EC(50) = 76 nM), thus demonstrating it to be one of the most potent natural LXRalpha ligands known to date. 5,6-epoxycholesterol 13-19 nuclear receptor subfamily 1 group H member 3 Homo sapiens 159-167 32696532-7 2021 This review presents current knowledge as to the 5,6-EC metabolic pathway in BC focusing on the 5,6-EC metabolic enzymes ChEH and HSD11B2, and on 5,6-EC metabolite targets LXRbeta and GR. 5,6-epoxycholesterol 49-55 hydroxysteroid 11-beta dehydrogenase 2 Homo sapiens 130-137 32696532-7 2021 This review presents current knowledge as to the 5,6-EC metabolic pathway in BC focusing on the 5,6-EC metabolic enzymes ChEH and HSD11B2, and on 5,6-EC metabolite targets LXRbeta and GR. 5,6-epoxycholesterol 49-55 nuclear receptor subfamily 1 group H member 3 Homo sapiens 172-179 20117071-5 2010 For 0-, 100-, and 500-microg/ml CLA levels, the formation profiles of 7-hydroxycholesterol, 7-ketocholesterol, and 5,6-epoxycholesterol at 150 degrees C were fitted as multiple first-order curves, whereas a single first-order model could adequately describe 7-hydroperoxycholesterol and cholestane-3beta,5alpha,6beta-triol formation. 5,6-epoxycholesterol 115-135 selectin P ligand Homo sapiens 32-35