PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 29055739-14 2018 At the AF1 and contralateral AF2 regions, the DNA content of pMPC discs was significantly lower than injured control discs and MPC-injected discs. 2-methacryloyloxyethyl phosphorylcholine 62-65 interferon gamma receptor 2 Homo sapiens 7-10 28869709-0 2017 In vitro basic fibroblast growth factor (bFGF) delivery using an antithrombogenic 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer coated with a micropatterned diamond-like carbon (DLC) film. 2-methacryloyloxyethyl phosphorylcholine 124-127 fibroblast growth factor 2 Homo sapiens 41-45 28869709-1 2017 In this study, a newly designed drug-release platform composed of an antithrombogenic 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer was introduced, which was impregnated with basic fibroblast growth factor (bFGF) (bFGF/MPC polymer) to enhance the endothelial cell activation. 2-methacryloyloxyethyl phosphorylcholine 86-126 fibroblast growth factor 2 Homo sapiens 184-214 28869709-1 2017 In this study, a newly designed drug-release platform composed of an antithrombogenic 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer was introduced, which was impregnated with basic fibroblast growth factor (bFGF) (bFGF/MPC polymer) to enhance the endothelial cell activation. 2-methacryloyloxyethyl phosphorylcholine 86-126 fibroblast growth factor 2 Homo sapiens 216-220 28869709-1 2017 In this study, a newly designed drug-release platform composed of an antithrombogenic 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer was introduced, which was impregnated with basic fibroblast growth factor (bFGF) (bFGF/MPC polymer) to enhance the endothelial cell activation. 2-methacryloyloxyethyl phosphorylcholine 86-126 fibroblast growth factor 2 Homo sapiens 223-227 28869709-1 2017 In this study, a newly designed drug-release platform composed of an antithrombogenic 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer was introduced, which was impregnated with basic fibroblast growth factor (bFGF) (bFGF/MPC polymer) to enhance the endothelial cell activation. 2-methacryloyloxyethyl phosphorylcholine 128-131 fibroblast growth factor 2 Homo sapiens 184-214 28869709-1 2017 In this study, a newly designed drug-release platform composed of an antithrombogenic 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer was introduced, which was impregnated with basic fibroblast growth factor (bFGF) (bFGF/MPC polymer) to enhance the endothelial cell activation. 2-methacryloyloxyethyl phosphorylcholine 128-131 fibroblast growth factor 2 Homo sapiens 216-220 28869709-1 2017 In this study, a newly designed drug-release platform composed of an antithrombogenic 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer was introduced, which was impregnated with basic fibroblast growth factor (bFGF) (bFGF/MPC polymer) to enhance the endothelial cell activation. 2-methacryloyloxyethyl phosphorylcholine 128-131 fibroblast growth factor 2 Homo sapiens 223-227 27877881-3 2016 Two types of 2-methacryloyloxyethyl phosphorylcholine (MPC) copolymers bearing a thrombin-binding oligonucleotide aptamer and its complementary chain were independently synthesized by redox-initiated radical polymerization. 2-methacryloyloxyethyl phosphorylcholine 13-53 coagulation factor II, thrombin Homo sapiens 81-89 28869709-0 2017 In vitro basic fibroblast growth factor (bFGF) delivery using an antithrombogenic 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer coated with a micropatterned diamond-like carbon (DLC) film. 2-methacryloyloxyethyl phosphorylcholine 82-122 fibroblast growth factor 2 Homo sapiens 9-39 28869709-0 2017 In vitro basic fibroblast growth factor (bFGF) delivery using an antithrombogenic 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer coated with a micropatterned diamond-like carbon (DLC) film. 2-methacryloyloxyethyl phosphorylcholine 82-122 fibroblast growth factor 2 Homo sapiens 41-45 27327110-2 2016 The objectives of this study were to: (1) incorporate dimethylaminohexadecyl methacrylate (DMAHDM) and 2-methacryloyloxyethyl phosphorylcholine (MPC) into rechargeable NACP composite, and (2) investigate mechanical properties, protein adsorption and biofilm response of composite, and the pH of biofilm medium. 2-methacryloyloxyethyl phosphorylcholine 145-148 synuclein alpha Homo sapiens 168-172 28506845-5 2017 Coculture of CB with MPCs led to an expansion of total nucleated cells by a median factor of 12 and of CD34+ cells by a median factor of 49. 2-methacryloyloxyethyl phosphorylcholine 21-25 CD34 molecule Homo sapiens 103-107 26992370-2 2016 Poly[2-methacryloyloxyethyl phosphorylcholine (MPC)-ran-N-methacryloyl-(l)-tyrosinemethylester (MAT)] (P(MPC/MAT)) was synthesized by conventional radical polymerization, with the MAT units capable of being oxidized by 254nm UV irradiation. 2-methacryloyloxyethyl phosphorylcholine 47-50 methionine adenosyltransferase 1A Homo sapiens 109-112 19443203-4 2009 The FN recognition sites were constructed by integrating a surfactant as the ligand and immobilizing it with new biocompatible photoreactive phospholipid polymer composed of 2-methacryloyloxyethyl phosphorylcholine (MPC) units. 2-methacryloyloxyethyl phosphorylcholine 174-214 fibronectin 1 Homo sapiens 4-6 26893860-10 2016 EML4-ALK fusion genes appeared to occur significantly more frequently in PA-MPCs compared with PAs without MPC (P=0.027). 2-methacryloyloxyethyl phosphorylcholine 76-79 EMAP like 4 Homo sapiens 0-4 26893860-10 2016 EML4-ALK fusion genes appeared to occur significantly more frequently in PA-MPCs compared with PAs without MPC (P=0.027). 2-methacryloyloxyethyl phosphorylcholine 76-79 ALK receptor tyrosine kinase Homo sapiens 5-8 21295954-4 2011 Additionally, some of the MPC based polymeric surface was able to capture greater amount of carbonic anhydrase II than those of other polymers, when Sul was utilized as probe. 2-methacryloyloxyethyl phosphorylcholine 26-29 carbonic anhydrase 2 Homo sapiens 92-113 21302444-1 2010 OBJECTIVE: To test the effects and to identify appropriate dosage and possible mechanisms of recombinant human erythropoietin (rHuEPO) in treating MPC-11 myeloma in the BALB/c murine models. 2-methacryloyloxyethyl phosphorylcholine 147-150 erythropoietin Homo sapiens 111-125 20537380-0 2010 2-Methacryloyloxyethyl phosphorylcholine polymer (MPC)-coating improves the transfection activity of GALA-modified lipid nanoparticles by assisting the cellular uptake and intracellular dissociation of plasmid DNA in primary hepatocytes. 2-methacryloyloxyethyl phosphorylcholine 50-53 galactosidase alpha Homo sapiens 101-105 20537380-2 2010 We report herein that an additional coating of GALA-modified liposomes with 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer resulted in a two order of magnitude enhancement in the transfection activity of encapsulating plasmid DNA (pDNA). 2-methacryloyloxyethyl phosphorylcholine 76-116 galactosidase alpha Homo sapiens 47-51 20537380-2 2010 We report herein that an additional coating of GALA-modified liposomes with 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer resulted in a two order of magnitude enhancement in the transfection activity of encapsulating plasmid DNA (pDNA). 2-methacryloyloxyethyl phosphorylcholine 118-121 galactosidase alpha Homo sapiens 47-51 26992370-2 2016 Poly[2-methacryloyloxyethyl phosphorylcholine (MPC)-ran-N-methacryloyl-(l)-tyrosinemethylester (MAT)] (P(MPC/MAT)) was synthesized by conventional radical polymerization, with the MAT units capable of being oxidized by 254nm UV irradiation. 2-methacryloyloxyethyl phosphorylcholine 47-50 methionine adenosyltransferase 1A Homo sapiens 96-99 26992370-2 2016 Poly[2-methacryloyloxyethyl phosphorylcholine (MPC)-ran-N-methacryloyl-(l)-tyrosinemethylester (MAT)] (P(MPC/MAT)) was synthesized by conventional radical polymerization, with the MAT units capable of being oxidized by 254nm UV irradiation. 2-methacryloyloxyethyl phosphorylcholine 47-50 methionine adenosyltransferase 1A Homo sapiens 103-112 19443203-4 2009 The FN recognition sites were constructed by integrating a surfactant as the ligand and immobilizing it with new biocompatible photoreactive phospholipid polymer composed of 2-methacryloyloxyethyl phosphorylcholine (MPC) units. 2-methacryloyloxyethyl phosphorylcholine 216-219 fibronectin 1 Homo sapiens 4-6 34685159-5 2021 Our results predict that the monolayer and bilayer MPc (M = Co, Fe, Cu) molecular devices possess large advantages in designing high-performance electrical and spintronic molecular devices. 2-methacryloyloxyethyl phosphorylcholine 51-54 general transcription factor IIE subunit 1 Homo sapiens 64-66 15117211-0 2004 Evaluation of 2-methacryloyloxyethyl phosphorylcholine polymeric nanoparticle for immunoassay of C-reactive protein detection. 2-methacryloyloxyethyl phosphorylcholine 14-54 C-reactive protein Homo sapiens 97-115 34884505-6 2021 Both types of hmMSCs cultivated on collagen I hydrogels with hyaluronic acid (HA) or 2-methacryloyloxyethyl phosphorylcholine (MPC) and exposed to SAHA significantly downregulated focal adhesion kinase (PTK2) and activated ACTC1 and TNNT2. 2-methacryloyloxyethyl phosphorylcholine 85-125 protein tyrosine kinase 2 Homo sapiens 203-207 34884505-6 2021 Both types of hmMSCs cultivated on collagen I hydrogels with hyaluronic acid (HA) or 2-methacryloyloxyethyl phosphorylcholine (MPC) and exposed to SAHA significantly downregulated focal adhesion kinase (PTK2) and activated ACTC1 and TNNT2. 2-methacryloyloxyethyl phosphorylcholine 85-125 actin alpha cardiac muscle 1 Homo sapiens 223-228 34884505-6 2021 Both types of hmMSCs cultivated on collagen I hydrogels with hyaluronic acid (HA) or 2-methacryloyloxyethyl phosphorylcholine (MPC) and exposed to SAHA significantly downregulated focal adhesion kinase (PTK2) and activated ACTC1 and TNNT2. 2-methacryloyloxyethyl phosphorylcholine 85-125 troponin T2, cardiac type Homo sapiens 233-238 34884505-6 2021 Both types of hmMSCs cultivated on collagen I hydrogels with hyaluronic acid (HA) or 2-methacryloyloxyethyl phosphorylcholine (MPC) and exposed to SAHA significantly downregulated focal adhesion kinase (PTK2) and activated ACTC1 and TNNT2. 2-methacryloyloxyethyl phosphorylcholine 127-130 protein tyrosine kinase 2 Homo sapiens 203-207 34884505-6 2021 Both types of hmMSCs cultivated on collagen I hydrogels with hyaluronic acid (HA) or 2-methacryloyloxyethyl phosphorylcholine (MPC) and exposed to SAHA significantly downregulated focal adhesion kinase (PTK2) and activated ACTC1 and TNNT2. 2-methacryloyloxyethyl phosphorylcholine 127-130 actin alpha cardiac muscle 1 Homo sapiens 223-228 34884505-6 2021 Both types of hmMSCs cultivated on collagen I hydrogels with hyaluronic acid (HA) or 2-methacryloyloxyethyl phosphorylcholine (MPC) and exposed to SAHA significantly downregulated focal adhesion kinase (PTK2) and activated ACTC1 and TNNT2. 2-methacryloyloxyethyl phosphorylcholine 127-130 troponin T2, cardiac type Homo sapiens 233-238 17299267-1 2007 The immunopharmacological profile of novel biocompatible water-soluble interleukin-2 (IL-2)-conjugated 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer immunosuppressive agents was established. 2-methacryloyloxyethyl phosphorylcholine 103-143 interleukin 2 Homo sapiens 71-84 17299267-1 2007 The immunopharmacological profile of novel biocompatible water-soluble interleukin-2 (IL-2)-conjugated 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer immunosuppressive agents was established. 2-methacryloyloxyethyl phosphorylcholine 103-143 interleukin 2 Homo sapiens 86-90 17299267-1 2007 The immunopharmacological profile of novel biocompatible water-soluble interleukin-2 (IL-2)-conjugated 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer immunosuppressive agents was established. 2-methacryloyloxyethyl phosphorylcholine 145-148 interleukin 2 Homo sapiens 71-84 17299267-1 2007 The immunopharmacological profile of novel biocompatible water-soluble interleukin-2 (IL-2)-conjugated 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer immunosuppressive agents was established. 2-methacryloyloxyethyl phosphorylcholine 145-148 interleukin 2 Homo sapiens 86-90 11197499-1 2001 To obtain protein-adsorption-resistant membrane for hemodialysis, we prepared a polymer blend composed of polysulfone and 2-methacryloyloxyethyl phosphorylcholine (MPC) polymer (PSf/MPC polymer). 2-methacryloyloxyethyl phosphorylcholine 122-162 insulin like growth factor binding protein 7 Homo sapiens 178-181 10555087-8 1999 The amount of adsorbed fibronectin on the PE grafted with poly[2-methacryloyloxyethyl phospohorylcholine(MPC)] and poly(MHPC) decreased with an increase in their surface density. 2-methacryloyloxyethyl phosphorylcholine 105-108 fibronectin 1 Homo sapiens 23-34 3936614-4 1985 Partially thiolated polycytidylic acid (MPC) strongly inhibited only the DNA polymerase alpha of the "normal" cell line, whereas the corresponding enzymes of all three leukemic cell lines were relatively insensitive to MPC. 2-methacryloyloxyethyl phosphorylcholine 40-43 DNA polymerase alpha 1, catalytic subunit Homo sapiens 73-93 33121533-8 2020 Here, we shed light on the role of NKX6.1 during pancreatic beta cell development and in directing the MPCs to functional monohormonal lineage. 2-methacryloyloxyethyl phosphorylcholine 103-107 NK6 homeobox 1 Homo sapiens 35-41 1000498-5 1976 In comparison, the DNA polymerase beta which was purified from normal rat liver nuclear fraction, was much less sensitive to inhibition by MPC. 2-methacryloyloxyethyl phosphorylcholine 139-142 DNA polymerase beta Rattus norvegicus 19-38 33353870-10 2021 Furthermore, PCM directly correlated with serum PSA levels, with mortality rates reaching up to 50% and 70% for PSA >50 ng/dl for LPC and MPC, respectively. 2-methacryloyloxyethyl phosphorylcholine 138-141 kallikrein related peptidase 3 Homo sapiens 48-51 32301466-6 2020 The interaction of interleukin 6 with the antibodies produces a blue-shift in resonant wavelength and the reflectance intensity increases up to 50% and 44% when tested with CoF & magnetite based MPC respectively at a concentration of 50 pg ml-1. 2-methacryloyloxyethyl phosphorylcholine 195-198 interleukin 6 Homo sapiens 19-32 31033952-5 2019 This article describes the technique of MPC-Exo purification and transplantation into hearts of DMDMDX mutant mice. 2-methacryloyloxyethyl phosphorylcholine 40-43 5'-3' exoribonuclease 1 Mus musculus 44-47 32192339-2 2020 In this report, human hair keratin was extracted with a reduction method and then conjugated with zwitterionic poly(2-methacryloxyethyl phosphatidylcholine, MPC) via thiol chain transfer polymerization(Thiol CTP). 2-methacryloyloxyethyl phosphorylcholine 157-160 solute carrier family 25 member 1 Homo sapiens 208-211 31932833-5 2020 After 24-week implantation in the submuscular pockets of Yorkshire pigs, the heat-induced MPC-grafted breast implants showed 45% smaller capsular thickness and 20-30% lower levels of inflammatory markers such as myeloperoxidase (MPO), transforming growth factor-beta (TGF-beta), and alpha-smooth muscle actin (alpha-SMA) in surrounding tissues compared to non-grafted implants. 2-methacryloyloxyethyl phosphorylcholine 90-93 myeloperoxidase Sus scrofa 212-227 31932833-5 2020 After 24-week implantation in the submuscular pockets of Yorkshire pigs, the heat-induced MPC-grafted breast implants showed 45% smaller capsular thickness and 20-30% lower levels of inflammatory markers such as myeloperoxidase (MPO), transforming growth factor-beta (TGF-beta), and alpha-smooth muscle actin (alpha-SMA) in surrounding tissues compared to non-grafted implants. 2-methacryloyloxyethyl phosphorylcholine 90-93 myeloperoxidase Sus scrofa 229-232 32228944-2 2020 The 2-methacryloyloxyethyl phosphorylcholine (MPC) was first reacted with alpha-thioglycerol by Michael addition to give a diol compound (MPC-diol), then the SPU-PCs with various PC content were prepared by a one-step chain extension of the mixture of MPC-diol and poly(epsilon-caprolactone) diol (PCL-diol) with aliphatic diurethane diisocyanates (HBH). 2-methacryloyloxyethyl phosphorylcholine 4-44 hemoglobin subunit alpha 1 Homo sapiens 349-352 32228944-2 2020 The 2-methacryloyloxyethyl phosphorylcholine (MPC) was first reacted with alpha-thioglycerol by Michael addition to give a diol compound (MPC-diol), then the SPU-PCs with various PC content were prepared by a one-step chain extension of the mixture of MPC-diol and poly(epsilon-caprolactone) diol (PCL-diol) with aliphatic diurethane diisocyanates (HBH). 2-methacryloyloxyethyl phosphorylcholine 46-49 hemoglobin subunit alpha 1 Homo sapiens 349-352 30742145-6 2019 In this work, bone morphogenetic protein-2 (BMP-2), 2-(methacryloyloxy)ethyl phosphorylcholine (MPC) and the bisacryloylated VPLGVRTK peptide were respectively used as the model growth factor, monomer, and MMP-cleavable crosslinker. 2-methacryloyloxyethyl phosphorylcholine 96-99 bone morphogenetic protein 2 Homo sapiens 14-42 29728047-1 2019 In this study, poly[2-methacryloyloxyethyl phosphorylcholine (MPC)]-protected Fe3O4 nanoparticles were prepared and used for the label-free specific detection and collection of an acute inflammation marker, C-reactive protein (CRP), in a simulated body fluid. 2-methacryloyloxyethyl phosphorylcholine 62-65 C-reactive protein Homo sapiens 207-225 29728047-1 2019 In this study, poly[2-methacryloyloxyethyl phosphorylcholine (MPC)]-protected Fe3O4 nanoparticles were prepared and used for the label-free specific detection and collection of an acute inflammation marker, C-reactive protein (CRP), in a simulated body fluid. 2-methacryloyloxyethyl phosphorylcholine 62-65 C-reactive protein Homo sapiens 227-230 30439686-5 2019 Forced overexpression of MPC promote the production of reactive oxygen species and enhance the apoptosis induced by IFNgamma in colon cancer cells. 2-methacryloyloxyethyl phosphorylcholine 25-28 interferon gamma Homo sapiens 116-124 30412376-3 2018 In this study, inspired by the highly specific interaction between CRP and the cell membrane, an excellent anti-biofouling compound 2-(methacryloyloxy)ethyl phosphorylcholine and a highly hydrophilic crosslinker N, N"-methylenebisacrylamide were employed to fabricate a novel cell membrane biomimetic polymer for selective capture of CRP in the presence of calcium ions. 2-methacryloyloxyethyl phosphorylcholine 132-174 C-reactive protein Homo sapiens 67-70 30412376-3 2018 In this study, inspired by the highly specific interaction between CRP and the cell membrane, an excellent anti-biofouling compound 2-(methacryloyloxy)ethyl phosphorylcholine and a highly hydrophilic crosslinker N, N"-methylenebisacrylamide were employed to fabricate a novel cell membrane biomimetic polymer for selective capture of CRP in the presence of calcium ions. 2-methacryloyloxyethyl phosphorylcholine 132-174 C-reactive protein Homo sapiens 334-337 30269864-17 2018 SIGNIFICANCE: Incorporating 3% MPC into NACP nanocomposite greatly reduced protein adsorption, biofilm growth and lactic acid, decreasing biofilm CFU by nearly 2 logs, without compromising Ca and P recharge. 2-methacryloyloxyethyl phosphorylcholine 31-34 synuclein alpha Homo sapiens 40-44 30153499-12 2018 CLINICAL SIGNIFICANCE: Novel bioactive adhesive containing MPC + NACP is promising to repel proteins and bacteria, and inhibit secondary caries at the restoration margins. 2-methacryloyloxyethyl phosphorylcholine 59-62 synuclein alpha Homo sapiens 65-69