PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
14667928-0	2004	Propolin C from propolis induces apoptosis through activating caspases, Bid and cytochrome c release in human melanoma cells.	propolin C	0-10	BH3 interacting domain death agonist	Homo sapiens	72-75
29681982-0	2018	Propolin C Inhibited Migration and Invasion via Suppression of EGFR-Mediated Epithelial-to-Mesenchymal Transition in Human Lung Cancer Cells.	propolin C	0-10	epidermal growth factor receptor	Homo sapiens	63-67
29681982-4	2018	In this study, the antimigration and anti-invasion activities of propolin C, a c-prenylflavanone from Taiwanese propolis, were investigated on EGFR-regulated EMT signaling pathway.	propolin C	65-75	epidermal growth factor receptor	Homo sapiens	143-147
29681982-6	2018	Downregulations of vimentin and snail as well as upregulation of E-cadherin expressions were through the inhibition of EGFR-mediated phosphatidylinositol-3-kinase/protein kinase B (PI3K/Akt) and extracellular signal-regulated kinase (ERK) signaling pathway in propolin C-treated cells.	propolin C	260-270	cadherin 1	Homo sapiens	65-75
29681982-6	2018	Downregulations of vimentin and snail as well as upregulation of E-cadherin expressions were through the inhibition of EGFR-mediated phosphatidylinositol-3-kinase/protein kinase B (PI3K/Akt) and extracellular signal-regulated kinase (ERK) signaling pathway in propolin C-treated cells.	propolin C	260-270	epidermal growth factor receptor	Homo sapiens	119-123
29681982-6	2018	Downregulations of vimentin and snail as well as upregulation of E-cadherin expressions were through the inhibition of EGFR-mediated phosphatidylinositol-3-kinase/protein kinase B (PI3K/Akt) and extracellular signal-regulated kinase (ERK) signaling pathway in propolin C-treated cells.	propolin C	260-270	protein tyrosine kinase 2 beta	Homo sapiens	163-179
29681982-9	2018	Interestingly, EGF-induced expressions of vimentin, snail, and slug were suppressed through the inhibition of PI3K/Akt and ERK signaling pathway in propolin C-treated cells.	propolin C	148-158	vimentin	Homo sapiens	42-50
29681982-9	2018	Interestingly, EGF-induced expressions of vimentin, snail, and slug were suppressed through the inhibition of PI3K/Akt and ERK signaling pathway in propolin C-treated cells.	propolin C	148-158	snail family transcriptional repressor 1	Homo sapiens	52-57
29681982-9	2018	Interestingly, EGF-induced expressions of vimentin, snail, and slug were suppressed through the inhibition of PI3K/Akt and ERK signaling pathway in propolin C-treated cells.	propolin C	148-158	AKT serine/threonine kinase 1	Homo sapiens	115-118
29681982-9	2018	Interestingly, EGF-induced expressions of vimentin, snail, and slug were suppressed through the inhibition of PI3K/Akt and ERK signaling pathway in propolin C-treated cells.	propolin C	148-158	mitogen-activated protein kinase 1	Homo sapiens	123-126
29681982-10	2018	Inhibition of cell migration and invasion by propolin C was through the inhibition of EGF/EGFR-mediated signaling pathway, followed by EMT suppression in lung cancer.	propolin C	45-55	epidermal growth factor receptor	Homo sapiens	90-94
23710238-5	2013	At the molecular level, nymphaeol-A markedly inactivated mitogen-activated protein kinase/ERK kinase 1/2 (MEK1/2) and extracellular signal-regulated kinase 1/2 (ERK1/2), whose molecular activations signal new vessel formation in HUVECs.	propolin C	24-35	mitogen-activated protein kinase kinase 1	Homo sapiens	106-112
23710238-5	2013	At the molecular level, nymphaeol-A markedly inactivated mitogen-activated protein kinase/ERK kinase 1/2 (MEK1/2) and extracellular signal-regulated kinase 1/2 (ERK1/2), whose molecular activations signal new vessel formation in HUVECs.	propolin C	24-35	mitogen-activated protein kinase 1	Homo sapiens	118-159
23710238-5	2013	At the molecular level, nymphaeol-A markedly inactivated mitogen-activated protein kinase/ERK kinase 1/2 (MEK1/2) and extracellular signal-regulated kinase 1/2 (ERK1/2), whose molecular activations signal new vessel formation in HUVECs.	propolin C	24-35	mitogen-activated protein kinase 3	Homo sapiens	161-167
23710238-7	2013	Taken together, nymphaeol-A was shown to inhibit angiogenesis at least in part via inactivation of MEK1/2-ERK1/2 signaling and induction of caspase-dependent apoptosis.	propolin C	16-27	mitogen-activated protein kinase kinase 1	Homo sapiens	99-105
23710238-7	2013	Taken together, nymphaeol-A was shown to inhibit angiogenesis at least in part via inactivation of MEK1/2-ERK1/2 signaling and induction of caspase-dependent apoptosis.	propolin C	16-27	mitogen-activated protein kinase 3	Homo sapiens	106-112
14667928-0	2004	Propolin C from propolis induces apoptosis through activating caspases, Bid and cytochrome c release in human melanoma cells.	propolin C	0-10	cytochrome c, somatic	Homo sapiens	80-92
14667928-9	2004	Moreover, propolin C was capable of releasing cytochrome c from mitochondria to cytosol.	propolin C	10-20	cytochrome c, somatic	Homo sapiens	46-58