PMID-sentid	Pub_year	Sent_text	compound_name	comp_offset	prot_official_name	organism	prot_offset
2538223-1	1989	Isopropyl methanesulfonate (IMS), a direct-acting SN1 alkylating agent, induced thymic lymphomas in 29 of 30 female Hsd: (ICR)BR mice by the 139th day following once a week subcutaneous injections at a dose of 10 mumol/mouse.	isopropylmethanesulfonate	0-26	solute carrier family 38, member 3	Mus musculus	50-53
2538223-1	1989	Isopropyl methanesulfonate (IMS), a direct-acting SN1 alkylating agent, induced thymic lymphomas in 29 of 30 female Hsd: (ICR)BR mice by the 139th day following once a week subcutaneous injections at a dose of 10 mumol/mouse.	isopropylmethanesulfonate	0-26	histidine ammonia lyase	Mus musculus	116-119
2538223-1	1989	Isopropyl methanesulfonate (IMS), a direct-acting SN1 alkylating agent, induced thymic lymphomas in 29 of 30 female Hsd: (ICR)BR mice by the 139th day following once a week subcutaneous injections at a dose of 10 mumol/mouse.	isopropylmethanesulfonate	28-31	solute carrier family 38, member 3	Mus musculus	50-53
2538223-1	1989	Isopropyl methanesulfonate (IMS), a direct-acting SN1 alkylating agent, induced thymic lymphomas in 29 of 30 female Hsd: (ICR)BR mice by the 139th day following once a week subcutaneous injections at a dose of 10 mumol/mouse.	isopropylmethanesulfonate	28-31	histidine ammonia lyase	Mus musculus	116-119
3018764-1	1986	The direct-acting SN1 alkylating agent isopropyl methanesulfonate (IMS) was carcinogenic by subcutaneous injection in female Hsd:(ICR)BR mice, causing thymic lymphoid neoplasms within 7 months in at least 20 of 32 treated mice.	isopropylmethanesulfonate	39-65	solute carrier family 38, member 3	Mus musculus	18-21
3034413-0	1987	Induction of thymic lymphomas and squamous cell carcinomas following topic application of isopropyl methanesulfonate to female Hsd:(ICR)BR mice.	isopropylmethanesulfonate	90-116	histidine ammonia lyase	Mus musculus	127-130
3034413-1	1987	The goal of these experiments in female Hsd:(ICR)Br mice was to determine whether the direct-acting SN1 alkylating carcinogen isopropyl methanesulfonate (IMS) is carcinogenic and to compare its effects with those of the direct-acting SN2 methyl homologue, methyl methanesulfonate (MMS).	isopropylmethanesulfonate	126-152	solute carrier family 38, member 3	Mus musculus	100-103
3034413-1	1987	The goal of these experiments in female Hsd:(ICR)Br mice was to determine whether the direct-acting SN1 alkylating carcinogen isopropyl methanesulfonate (IMS) is carcinogenic and to compare its effects with those of the direct-acting SN2 methyl homologue, methyl methanesulfonate (MMS).	isopropylmethanesulfonate	154-157	solute carrier family 38, member 3	Mus musculus	100-103
3018764-1	1986	The direct-acting SN1 alkylating agent isopropyl methanesulfonate (IMS) was carcinogenic by subcutaneous injection in female Hsd:(ICR)BR mice, causing thymic lymphoid neoplasms within 7 months in at least 20 of 32 treated mice.	isopropylmethanesulfonate	67-70	solute carrier family 38, member 3	Mus musculus	18-21
27931802-0	2016	Evaluation of in vivo mutagenicity of isopropyl methanesulfonate by RBC Pig-a and PIGRET assays.	isopropylmethanesulfonate	38-64	phosphatidylinositol glycan anchor biosynthesis class A	Sus scrofa	72-77
10218442-1	1999	A glutathione reductase (GR) mutant with approximately 50% residual enzyme activity in blood compared with wild-type was detected amongst offspring of isopropyl methanesulphonate-treated male mice.	isopropylmethanesulfonate	151-178	glutathione reductase	Mus musculus	2-23
10218442-1	1999	A glutathione reductase (GR) mutant with approximately 50% residual enzyme activity in blood compared with wild-type was detected amongst offspring of isopropyl methanesulphonate-treated male mice.	isopropylmethanesulfonate	151-178	glutathione reductase	Mus musculus	25-27