PMID-sentid Pub_year Sent_text compound_name comp_offset prot_official_name organism prot_offset 32226300-8 2020 Our data indicate that BMDC has the potential to improve the treatment of primary EGFR-TKI resistant NISCLC that cannot be controlled with single-target agent, such as icotinib. bmdc 23-27 epidermal growth factor receptor Homo sapiens 82-86 30984180-5 2019 We investigated the effects of vitamin D on murine CD11c+ bone marrow derived DC (BMDC) function by analyzing global gene expression in CD11c+ BMDC generated in the presence (VitD-CD11c+BMDC) or absence (Veh-CD11c+BMDC) of the active vitamin D metabolite, 1,25-dihydroxyvitamin D3 (1,25(OH)2D3). bmdc 82-86 integrin alpha X Mus musculus 51-56 32106265-10 2020 Blockade of ACC1 resulted in metabolic reprogramming of BMDC that ameliorated mitochondrial dysfunction and reduced pathologic innate immune cytokines in DC. bmdc 56-60 acetyl-CoA carboxylase alpha Homo sapiens 12-16 30561085-10 2019 CONCLUSION: Exosomes derived from LIPUS-treated BMDC inhibit TNFalpha-induced endothelial inflammation by inhibiting the nuclear factor-kappaB signaling pathway. bmdc 48-52 tumor necrosis factor Homo sapiens 61-69 29912595-9 2019 The co-incubation of BMDC with supernatants of activated, irradiated pMF significantly reduced the CD40 expression, but did not impact on the BMDC-derived induction of T-cell proliferation. bmdc 21-25 CD40 antigen Mus musculus 99-103 27857212-3 2016 We investigated the effects of CpdA on in vitro generated GM-CSF-conditioned bone marrow-derived DC (BMDC). bmdc 101-105 colony stimulating factor 2 Homo sapiens 58-64 29390039-6 2018 Finally, BMDC lacking SAA3 demonstrate an impaired endotoxin tolerance response and inhibited responses to retinoic acid. bmdc 9-13 serum amyloid A 3 Mus musculus 22-26 29218051-5 2017 From 24 h on after CLP, BMC gave rise to BMDC that released enhanced levels of IL-10. bmdc 41-45 interleukin 10 Mus musculus 79-84 29218051-7 2017 Prior depletion of the CD11chiMHCII+CD4+ DCs from BMC in vitro reversed the increased IL-10 secretion of subsequently differentiating BMDC. bmdc 134-138 CD4 antigen Mus musculus 36-39 29218051-7 2017 Prior depletion of the CD11chiMHCII+CD4+ DCs from BMC in vitro reversed the increased IL-10 secretion of subsequently differentiating BMDC. bmdc 134-138 interleukin 10 Mus musculus 86-91 28202390-7 2017 RPE65-BMDC administration was most effective in early disease, when visual function and retinal morphology returned to near normal, and less effective in late-stage disease. bmdc 6-10 retinal pigment epithelium 65 Mus musculus 0-5 27815442-5 2016 We show that murine bone marrow-derived DC (BMDC) maturation induced by LPS, as opposed to polyinosinic:polycytidylic acid or cytosine-phosphate-guanine, is robustly inhibited by vascular endothelial growth factor (VEGF), a previously identified immunosuppressive cytokine. bmdc 44-48 vascular endothelial growth factor A Mus musculus 179-213 27815442-5 2016 We show that murine bone marrow-derived DC (BMDC) maturation induced by LPS, as opposed to polyinosinic:polycytidylic acid or cytosine-phosphate-guanine, is robustly inhibited by vascular endothelial growth factor (VEGF), a previously identified immunosuppressive cytokine. bmdc 44-48 vascular endothelial growth factor A Mus musculus 215-219 27815442-8 2016 However, NRP-1-deficient BMDC remained completely insensitive to the VEGF-dependent inhibition of BMDC maturation in culture. bmdc 25-29 neuropilin 1 Mus musculus 9-14 27466155-4 2016 In this study we showed that rapamycin treatment on RSV-infected murine bone marrow-derived DC (BMDC) decreases the frequency of CD8(+)CD44(high) T cells. bmdc 96-100 CD8a molecule Homo sapiens 129-132 27466155-5 2016 However, inhibition of mTOR on RSV-infected BMDC did not modify the activation phenotype of these cells. bmdc 44-48 mechanistic target of rapamycin kinase Homo sapiens 23-27 26635791-7 2015 Instead, we discovered that the addition of 1,25(OH)2D3 to BMDC cultures resulted in a significant reduction in the proportion of CD11c+ cells. bmdc 59-63 integrin subunit alpha X Homo sapiens 130-135 26519533-7 2015 injection of IgM/LPS-pretreated BMDC or using IL-10 knockout BMDC fails to induce protection. bmdc 61-65 interleukin 10 Mus musculus 46-51 26519533-8 2015 Similarly, IgM/LPS-pretreated BMDC are rendered nonprotective by increasing CD40 expression and phosphorylation of p65 NF-kappaB. bmdc 30-34 CD40 antigen Mus musculus 76-80 26519533-8 2015 Similarly, IgM/LPS-pretreated BMDC are rendered nonprotective by increasing CD40 expression and phosphorylation of p65 NF-kappaB. bmdc 30-34 v-rel reticuloendotheliosis viral oncogene homolog A (avian) Mus musculus 115-118 26635791-8 2015 Purified CD11c+ VitD-BMDC were significantly less effective at priming T cells in vitro yet were similarly capable of initiating EAE as vehicle-treated CD11c+ BMDC. bmdc 21-25 integrin subunit alpha X Homo sapiens 152-157 26549577-3 2015 BMDC treated with MG:OVA induced significantly higher numbers of activated (CD25+CD69+) OVA-specific CD4+ T cells than BMDC treated with OVA alone. bmdc 0-4 interleukin 2 receptor subunit alpha Homo sapiens 76-80 26549577-4 2015 BMDC treated with MG:OVA upregulated CD86 and CD40 expression as well as MG alone, indicating that conjugation of OVA does not alter the immunostimulatory capacity of MG. Activation of CD8+ OVA-specific OT-1 cells showed that MG:OVA is also capable of enhancing cross-presentation by BMDC to CD8+ cytotoxic T cells. bmdc 0-4 CD40 molecule Homo sapiens 46-50 26549577-4 2015 BMDC treated with MG:OVA upregulated CD86 and CD40 expression as well as MG alone, indicating that conjugation of OVA does not alter the immunostimulatory capacity of MG. Activation of CD8+ OVA-specific OT-1 cells showed that MG:OVA is also capable of enhancing cross-presentation by BMDC to CD8+ cytotoxic T cells. bmdc 0-4 CD8a molecule Homo sapiens 185-188 26549577-3 2015 BMDC treated with MG:OVA induced significantly higher numbers of activated (CD25+CD69+) OVA-specific CD4+ T cells than BMDC treated with OVA alone. bmdc 0-4 CD69 molecule Homo sapiens 81-85 26549577-3 2015 BMDC treated with MG:OVA induced significantly higher numbers of activated (CD25+CD69+) OVA-specific CD4+ T cells than BMDC treated with OVA alone. bmdc 0-4 CD4 molecule Homo sapiens 101-104 26083387-4 2015 Kdm5b-specific siRNA inhibition in BMDC led to a 10-fold increase in IFN-beta as well as increases in IL-6 and TNF-alpha compared to control-transfected cells. bmdc 35-39 interleukin 6 Homo sapiens 102-106 26268402-7 2015 We observed that ES-treated BMDC co-cultured with DO11.10 transgenic CD4(+) T cells induced the generation of CD4(+)CD25(+)Foxp3(+) T cells. bmdc 28-32 CD4 antigen Mus musculus 69-72 26268402-7 2015 We observed that ES-treated BMDC co-cultured with DO11.10 transgenic CD4(+) T cells induced the generation of CD4(+)CD25(+)Foxp3(+) T cells. bmdc 28-32 CD4 antigen Mus musculus 110-113 26268402-7 2015 We observed that ES-treated BMDC co-cultured with DO11.10 transgenic CD4(+) T cells induced the generation of CD4(+)CD25(+)Foxp3(+) T cells. bmdc 28-32 interleukin 2 receptor, alpha chain Mus musculus 116-120 26083387-4 2015 Kdm5b-specific siRNA inhibition in BMDC led to a 10-fold increase in IFN-beta as well as increases in IL-6 and TNF-alpha compared to control-transfected cells. bmdc 35-39 lysine demethylase 5B Homo sapiens 0-5 26083387-4 2015 Kdm5b-specific siRNA inhibition in BMDC led to a 10-fold increase in IFN-beta as well as increases in IL-6 and TNF-alpha compared to control-transfected cells. bmdc 35-39 tumor necrosis factor Homo sapiens 111-120 25454807-0 2015 Temporary elimination of IL-10 enhanced the effectiveness of cyclophosphamide and BMDC-based therapy by decrease of the suppressor activity of MDSCs and activation of antitumour immune response. bmdc 82-86 interleukin 10 Mus musculus 25-30 26083387-4 2015 Kdm5b-specific siRNA inhibition in BMDC led to a 10-fold increase in IFN-beta as well as increases in IL-6 and TNF-alpha compared to control-transfected cells. bmdc 35-39 interferon beta 1 Homo sapiens 69-77 25949867-7 2015 STAT5 activation, Foxp3 expression, and hnRNPE1 activation mediated by PI3K/Akt signaling were required for Dab2 expression during GM-CSF-derived BMDC development regardless of TGF-beta signaling. bmdc 146-150 signal transducer and activator of transcription 5A Mus musculus 0-5 25949867-7 2015 STAT5 activation, Foxp3 expression, and hnRNPE1 activation mediated by PI3K/Akt signaling were required for Dab2 expression during GM-CSF-derived BMDC development regardless of TGF-beta signaling. bmdc 146-150 poly(rC) binding protein 1 Mus musculus 40-47 25949867-7 2015 STAT5 activation, Foxp3 expression, and hnRNPE1 activation mediated by PI3K/Akt signaling were required for Dab2 expression during GM-CSF-derived BMDC development regardless of TGF-beta signaling. bmdc 146-150 disabled 2, mitogen-responsive phosphoprotein Mus musculus 108-112 25949867-7 2015 STAT5 activation, Foxp3 expression, and hnRNPE1 activation mediated by PI3K/Akt signaling were required for Dab2 expression during GM-CSF-derived BMDC development regardless of TGF-beta signaling. bmdc 146-150 colony stimulating factor 2 (granulocyte-macrophage) Mus musculus 131-137 25457882-5 2015 In contrast, the expression level of IFN-gamma and T-bet mRNA, signaling molecules for Th1 cells, was higher in peptide 19-immunized group than in PBS-immunized group.In non-immunized wild mice, BMDC-derived CD11c+ dendritic cells have shown to stimulate Tregs significantly in antigen-nonspecific manner. bmdc 195-199 interferon gamma Mus musculus 37-46 25457882-5 2015 In contrast, the expression level of IFN-gamma and T-bet mRNA, signaling molecules for Th1 cells, was higher in peptide 19-immunized group than in PBS-immunized group.In non-immunized wild mice, BMDC-derived CD11c+ dendritic cells have shown to stimulate Tregs significantly in antigen-nonspecific manner. bmdc 195-199 T-box 21 Mus musculus 51-56 24347266-8 2014 However, when BMDCs from paclitaxel-treated mice were injected into wild-type EMT/6-bearing mice, a substantial increase in tumor growth and BMDC infiltration was detected compared to osteopontin-depleted EMT/6-bearing mice injected with BMDCs from paclitaxel-treated mice. bmdc 14-18 IL2 inducible T cell kinase Mus musculus 78-81 24347266-8 2014 However, when BMDCs from paclitaxel-treated mice were injected into wild-type EMT/6-bearing mice, a substantial increase in tumor growth and BMDC infiltration was detected compared to osteopontin-depleted EMT/6-bearing mice injected with BMDCs from paclitaxel-treated mice. bmdc 14-18 secreted phosphoprotein 1 Mus musculus 184-195 24752333-6 2014 Collectively, our results suggest that the neutralization of VEGF-A in cultured tumor cells can block TMP-induced BMDC mobilization and colonization of tumors and hence provide another mechanism of action by which antiangiogenic drugs act to inhibit tumor growth and angiogenesis. bmdc 114-118 vascular endothelial growth factor A Mus musculus 61-67 24379281-2 2014 Spherules are the tissue form of Coccidioides, and we determined that the MR on bone marrow-derived dendritic cells (BMDC) was important for recognition of spherules (formalin-killed spherules [FKS]) and for secretion of interleukin 10 (IL-10) and proinflammatory cytokines in response to FKS by both elicited macrophages and BMDC. bmdc 117-121 interleukin 10 Mus musculus 237-242 24078693-4 2013 Notably, Dox-induced production of mature IL-1beta was temporally correlated with caspase-8 activation in WT cells and greatly suppressed in Casp8(-/-)Rip3(-/-) or Trif(-/-) BMDC, as well as in WT BMDC treated with the caspase-8 inhibitor, IETD. bmdc 174-178 interleukin 1 beta Mus musculus 42-50 24295831-5 2014 Activation of PPARgamma enhanced the ability of BMDC to polarize CD4 T cells toward iTregs and to induce T cell expression of the mucosal homing receptor, CCR9. bmdc 48-52 peroxisome proliferator activated receptor gamma Mus musculus 14-23 24295831-5 2014 Activation of PPARgamma enhanced the ability of BMDC to polarize CD4 T cells toward iTregs and to induce T cell expression of the mucosal homing receptor, CCR9. bmdc 48-52 chemokine (C-C motif) receptor 9 Mus musculus 155-159 24008730-6 2013 In comparison with untreated serum-starved BMDC, treatment with SAA downregulated mRNA expression of the pro-apoptotic molecule Bim, increased production of the pro-survival heat shock protein 70 (HSP70), and induced secretion of pro-inflammatory cytokines. bmdc 43-47 serum amyloid A1 cluster Homo sapiens 64-67 24008730-7 2013 SAA-treated BMDC that were serum starved for 48 h remained capable of presenting antigen and induced OTII CD4(+) T cells to secrete IL-17A, IL-17F, IL-21, IL-22, and IFNgamma in the presence of ovalbumin. bmdc 12-16 serum amyloid A1 cluster Homo sapiens 0-3 24008730-7 2013 SAA-treated BMDC that were serum starved for 48 h remained capable of presenting antigen and induced OTII CD4(+) T cells to secrete IL-17A, IL-17F, IL-21, IL-22, and IFNgamma in the presence of ovalbumin. bmdc 12-16 CD4 molecule Homo sapiens 106-109 24008730-7 2013 SAA-treated BMDC that were serum starved for 48 h remained capable of presenting antigen and induced OTII CD4(+) T cells to secrete IL-17A, IL-17F, IL-21, IL-22, and IFNgamma in the presence of ovalbumin. bmdc 12-16 interleukin 17A Homo sapiens 132-138 24008730-7 2013 SAA-treated BMDC that were serum starved for 48 h remained capable of presenting antigen and induced OTII CD4(+) T cells to secrete IL-17A, IL-17F, IL-21, IL-22, and IFNgamma in the presence of ovalbumin. bmdc 12-16 interleukin 17F Homo sapiens 140-146 24008730-7 2013 SAA-treated BMDC that were serum starved for 48 h remained capable of presenting antigen and induced OTII CD4(+) T cells to secrete IL-17A, IL-17F, IL-21, IL-22, and IFNgamma in the presence of ovalbumin. bmdc 12-16 interleukin 21 Homo sapiens 148-153 24008730-7 2013 SAA-treated BMDC that were serum starved for 48 h remained capable of presenting antigen and induced OTII CD4(+) T cells to secrete IL-17A, IL-17F, IL-21, IL-22, and IFNgamma in the presence of ovalbumin. bmdc 12-16 interleukin 22 Homo sapiens 155-160 24008730-7 2013 SAA-treated BMDC that were serum starved for 48 h remained capable of presenting antigen and induced OTII CD4(+) T cells to secrete IL-17A, IL-17F, IL-21, IL-22, and IFNgamma in the presence of ovalbumin. bmdc 12-16 interferon gamma Homo sapiens 166-174 24008730-9 2013 Measurement of Dex-responsive gene expression demonstrated CD4(+) T cells as the target of glucocorticoid hyperresponsiveness manifest as a consequence of BMDC stimulation by SAA. bmdc 155-159 CD4 molecule Homo sapiens 59-62 24008730-9 2013 Measurement of Dex-responsive gene expression demonstrated CD4(+) T cells as the target of glucocorticoid hyperresponsiveness manifest as a consequence of BMDC stimulation by SAA. bmdc 155-159 serum amyloid A1 cluster Homo sapiens 175-178 23609581-4 2013 The results revealed that cembrane-type diterpenoids, especially lobocrassin B, effectively inhibited LPS-induced BMDC activation by inhibiting the production of TNF-alpha. bmdc 114-118 tumor necrosis factor Mus musculus 162-171 23269491-8 2013 In conclusion, this study indicates that Mt- and mouse HSP70-treated BMDC can suppress PGIA via an IL-10-producing T cell-dependent manner. bmdc 69-73 heat shock protein 1B Mus musculus 55-60 23269491-8 2013 In conclusion, this study indicates that Mt- and mouse HSP70-treated BMDC can suppress PGIA via an IL-10-producing T cell-dependent manner. bmdc 69-73 interleukin 10 Mus musculus 99-104 22139376-10 2012 BMDC maturation was blunted by addition of an IFNbeta-neutralizing antibody. bmdc 0-4 interferon beta 1, fibroblast Mus musculus 46-53 22842304-5 2012 We also demonstrated that BMDC stimulation with Smteg resulted in significant IL-10 production. bmdc 26-30 interleukin 10 Mus musculus 78-83 23478188-2 2013 Activation of adenosine A2A receptor (A2AR) is generally considered to be antiinflammatory, inhibiting BMDC activities to protect against ALI. bmdc 103-107 adenosine A2a receptor Mus musculus 14-36 23478188-2 2013 Activation of adenosine A2A receptor (A2AR) is generally considered to be antiinflammatory, inhibiting BMDC activities to protect against ALI. bmdc 103-107 adenosine A2a receptor Mus musculus 38-42 23853721-4 2013 Using chemical inhibitors specific to protein kinases involved in activation of Fc gamma receptors (FcgammaRs), which mediate IgG signals, we found that hyperphosphorylation of ERK1/2 and Syk phosphorylation occurred after stimulation of BMDC with LPS and IVIG, and the increasing effect on IL-10 production was abolished by these inhibitors. bmdc 238-242 mitogen-activated protein kinase 3 Mus musculus 177-183 23853721-4 2013 Using chemical inhibitors specific to protein kinases involved in activation of Fc gamma receptors (FcgammaRs), which mediate IgG signals, we found that hyperphosphorylation of ERK1/2 and Syk phosphorylation occurred after stimulation of BMDC with LPS and IVIG, and the increasing effect on IL-10 production was abolished by these inhibitors. bmdc 238-242 spleen tyrosine kinase Mus musculus 188-191 23853721-6 2013 These findings suggest that IVIG induced the upregulation of IL-10 production through FcgammaRI activation, and IL-10 was indispensable to the suppressing effect of IVIG on the production of IL-12p70 in LPS-stimulated BMDC. bmdc 218-222 interleukin 10 Mus musculus 112-117 23079132-3 2012 G1-4A, enhanced surface expression of CD40, CD80, CD86, MHCII by BMDC in vitro and splenic DC in vivo. bmdc 65-69 CD40 antigen Mus musculus 38-42 22517116-8 2012 Blocking TNFalpha receptor 1 (TNFR1) completely abolished chemokine production, suggesting that BMDC-derived TNFalpha induced airway epithelial cell activation and enhancement of the innate immune response. bmdc 96-100 tumor necrosis factor Mus musculus 9-17 21825928-2 2011 Intravenous granulocyte-colony stimulating factor (G-CSF) is known to induce mobilization of BMDC to peripheral blood and the tissue levels of the stromal cell derived factor-1 (SDF-1) to be key in their homing to sites of injury. bmdc 93-97 colony stimulating factor 3 Rattus norvegicus 12-49 22517116-8 2012 Blocking TNFalpha receptor 1 (TNFR1) completely abolished chemokine production, suggesting that BMDC-derived TNFalpha induced airway epithelial cell activation and enhancement of the innate immune response. bmdc 96-100 tumor necrosis factor receptor superfamily, member 1a Mus musculus 30-35 22517116-8 2012 Blocking TNFalpha receptor 1 (TNFR1) completely abolished chemokine production, suggesting that BMDC-derived TNFalpha induced airway epithelial cell activation and enhancement of the innate immune response. bmdc 96-100 tumor necrosis factor Mus musculus 109-117 22348129-6 2012 However, stimulated SHARPIN-deficient BMDC had reduced transcription and secretion of pro-inflammatory mediators IL6, IL12P70, GMCSF, and nitric oxide. bmdc 38-42 colony stimulating factor 2 (granulocyte-macrophage) Mus musculus 127-132 22348129-8 2012 A mixed lymphocyte reaction showed that mutant BMDC only induced a weak Th1 immune response but stimulated increased Th2 cytokine production from allogeneic naive CD4(+) T cells. bmdc 47-51 heart and neural crest derivatives expressed 2 Mus musculus 117-120 22348129-8 2012 A mixed lymphocyte reaction showed that mutant BMDC only induced a weak Th1 immune response but stimulated increased Th2 cytokine production from allogeneic naive CD4(+) T cells. bmdc 47-51 CD4 antigen Mus musculus 163-166 21978934-9 2011 Moreover, chimeric mice reconstituted with BMDC where MMP9 activity was attenuated did not support accelerated metastasis by carcinoma cells that were pretreated with chemotherapy before their introduction to host animals. bmdc 43-47 matrix metallopeptidase 9 Mus musculus 54-58 21529994-3 2011 We show for the first time that the 24-hydroxylase enzyme is activated in bone marrow-derived dendritic cell (BMDC), due to 1,25(OH)2D3 stimulation which resulted in the induction of its gene, CYP24A1. bmdc 110-114 cytochrome P450 family 24 subfamily A member 1 Homo sapiens 193-200 21825928-2 2011 Intravenous granulocyte-colony stimulating factor (G-CSF) is known to induce mobilization of BMDC to peripheral blood and the tissue levels of the stromal cell derived factor-1 (SDF-1) to be key in their homing to sites of injury. bmdc 93-97 colony stimulating factor 3 Rattus norvegicus 51-56 20933096-9 2011 The expression of stem cell markers (Sca-1 or c-kit) was detected in BMDC-treated SGs. bmdc 69-73 ataxin 1 Mus musculus 37-42 21160046-5 2011 Adoptive transfer experiments of BMDC into naive mice revealed that BMDC from post-septic mice impaired Th1 priming but not Th cell expansion and suppressed the innate immune defense mechanisms against Pseudomonas bacteria in the lung. bmdc 33-37 negative elongation factor complex member C/D, Th1l Mus musculus 104-107 21160046-5 2011 Adoptive transfer experiments of BMDC into naive mice revealed that BMDC from post-septic mice impaired Th1 priming but not Th cell expansion and suppressed the innate immune defense mechanisms against Pseudomonas bacteria in the lung. bmdc 68-72 negative elongation factor complex member C/D, Th1l Mus musculus 104-107 21160046-6 2011 Accordingly, BMDC from post-septic mice inhibited the release of IFN-gamma from NK cells that are critical for the protection against Pseudomonas. bmdc 13-17 interferon gamma Mus musculus 65-74 20883723-7 2011 Finally, in vivo injection of GITR(-/-) OVA-loaded BMDC led to a lower cell number and a lower activated cell number in draining lymph nodes than in GITR(+/+) OVA-loaded BMDC injected mice. bmdc 51-55 tumor necrosis factor receptor superfamily, member 18 Mus musculus 30-34 20883723-7 2011 Finally, in vivo injection of GITR(-/-) OVA-loaded BMDC led to a lower cell number and a lower activated cell number in draining lymph nodes than in GITR(+/+) OVA-loaded BMDC injected mice. bmdc 51-55 tumor necrosis factor receptor superfamily, member 18 Mus musculus 149-153 20883723-7 2011 Finally, in vivo injection of GITR(-/-) OVA-loaded BMDC led to a lower cell number and a lower activated cell number in draining lymph nodes than in GITR(+/+) OVA-loaded BMDC injected mice. bmdc 170-174 tumor necrosis factor receptor superfamily, member 18 Mus musculus 30-34 20933096-9 2011 The expression of stem cell markers (Sca-1 or c-kit) was detected in BMDC-treated SGs. bmdc 69-73 KIT proto-oncogene receptor tyrosine kinase Mus musculus 46-51 20659463-9 2010 At 48 h post-infection, BMDC stimulated with LPS+IFN-gamma were able to eliminate the parasites. bmdc 24-28 interferon gamma Mus musculus 49-58 21057001-7 2010 Local iNOS from perivascular resident macrophages was found to be important for BMDC infiltration, since mice deficient in iNOS (Inos(-/-)) and mice with iNOS that had been inhibited by 1400W displayed reduced BMDC infiltration. bmdc 80-84 nitric oxide synthase 2, inducible Mus musculus 6-10 21057001-7 2010 Local iNOS from perivascular resident macrophages was found to be important for BMDC infiltration, since mice deficient in iNOS (Inos(-/-)) and mice with iNOS that had been inhibited by 1400W displayed reduced BMDC infiltration. bmdc 210-214 nitric oxide synthase 2, inducible Mus musculus 6-10 21108471-5 2010 Mechanistic studies highlighted that SIRP-alpha ligation by CD47-Fc on BMDC did not impair Ag uptake, Ag presentation and Ag-specific DO11.10 Tg Th2 priming and effector function in vitro, whereas in vivo administration of CD47-Fc or CD47-Fc-pretreated BMDC inhibited Tg T-cell proliferation, pinpointing that altered DC trafficking accounts for defective Th priming. bmdc 71-75 signal-regulatory protein alpha Mus musculus 37-47 21041655-4 2010 In the presence of LPS or CpG, Ahr-deficient (Ahr(-/-)) mature BMDC induced immune responses characterized by reduced Kyn and IL-10 production compared with results observed with tolerogenic mature WT BMDC. bmdc 63-67 aryl hydrocarbon receptor Homo sapiens 31-34 21041655-4 2010 In the presence of LPS or CpG, Ahr-deficient (Ahr(-/-)) mature BMDC induced immune responses characterized by reduced Kyn and IL-10 production compared with results observed with tolerogenic mature WT BMDC. bmdc 63-67 interleukin 10 Homo sapiens 126-131 20534768-6 2010 In the metaanalysis, we found the OPG SNP (rs4355801) and the RANK SNP (rs3018362) to be significantly associated with BMDC. bmdc 119-123 basic transcription factor 3 pseudogene 11 Homo sapiens 34-37 20813969-5 2010 By comparing both in vitro secretion and in vivo local induction of acute phase inflammatory cytokines by these cells, we identified monocyte chemoattractant factor 1 and tumor necrosis factor alpha as potential mediators of BMDC-induced tissue repair. bmdc 225-229 tumor necrosis factor Mus musculus 133-198 20813969-6 2010 In vivo analysis of BMDC-treated ischemic limbs and cutaneous wounds revealed that the production of monocyte chemoattractant factor 1 by exogenous and endogenous BMDCs is essential for BMDC-mediated vascular growth and tissue healing, while the inability of BMDCs to produce tumor necrosis factor alpha appears to play a lesser but still meaningful role. bmdc 20-24 tumor necrosis factor Mus musculus 276-303 20231889-4 2010 Loss of Jak2 significantly impaired DC development as manifested by reduced BMDC yield, smaller spleen size and reduced percentage of DCs in total splenocytes. bmdc 76-80 Janus kinase 2 Mus musculus 8-12 20661430-8 2010 Interestingly, we see that the BMDC activation is primarily due to signaling through the IFNAR and only marginally induced by the initial infection. bmdc 31-35 interferon alpha and beta receptor subunit 1 Homo sapiens 89-94 20525882-5 2010 In contrast, transfer of these same OVA/alphaGalCer BMDCs into IFN-gamma-deficient (IFN-gamma(-/-)) mice enhanced the development of these lung allergic responses, which was reversed by exogenous IFN-gamma treatment following OVA-BMDC transfer. bmdc 52-56 interferon gamma Mus musculus 63-72 20525882-5 2010 In contrast, transfer of these same OVA/alphaGalCer BMDCs into IFN-gamma-deficient (IFN-gamma(-/-)) mice enhanced the development of these lung allergic responses, which was reversed by exogenous IFN-gamma treatment following OVA-BMDC transfer. bmdc 52-56 interferon gamma Mus musculus 84-93 20525882-5 2010 In contrast, transfer of these same OVA/alphaGalCer BMDCs into IFN-gamma-deficient (IFN-gamma(-/-)) mice enhanced the development of these lung allergic responses, which was reversed by exogenous IFN-gamma treatment following OVA-BMDC transfer. bmdc 52-56 interferon gamma Mus musculus 84-93 20350561-12 2010 AhR activation by TCDD modulated BMDC uptake of both soluble and particulate antigens. bmdc 33-37 aryl-hydrocarbon receptor Mus musculus 0-3 20373289-3 2010 Immature, IL-10, TGF-beta and 1alpha,25-dihydroxyvitamin D(3)-modulated BMDC all induced tolerance to male skin in female TCR transgenic A1.RAG mice, and the modulated DC also tolerized after exposure to the TLR4-ligand LPS. bmdc 72-76 interleukin 10 Mus musculus 10-15 20373289-3 2010 Immature, IL-10, TGF-beta and 1alpha,25-dihydroxyvitamin D(3)-modulated BMDC all induced tolerance to male skin in female TCR transgenic A1.RAG mice, and the modulated DC also tolerized after exposure to the TLR4-ligand LPS. bmdc 72-76 toll-like receptor 4 Mus musculus 208-212 20145551-5 2010 We observed that BMDC, matured with a cytokine cocktail (tumor necrosis factor-alpha, interleukin-beta, interleukin-6, prostaglandin E2), strongly expressed CCR7. bmdc 17-21 C-C motif chemokine receptor 7 Homo sapiens 157-161 19761873-7 2009 Conversely, BMDC avoided the expression of IL-1beta at days 30 and 60 and TGF-beta only at day 30. bmdc 12-16 interleukin 1 beta Mus musculus 43-51 20145551-5 2010 We observed that BMDC, matured with a cytokine cocktail (tumor necrosis factor-alpha, interleukin-beta, interleukin-6, prostaglandin E2), strongly expressed CCR7. bmdc 17-21 tumor necrosis factor Homo sapiens 38-84 20145551-5 2010 We observed that BMDC, matured with a cytokine cocktail (tumor necrosis factor-alpha, interleukin-beta, interleukin-6, prostaglandin E2), strongly expressed CCR7. bmdc 17-21 interleukin 6 Homo sapiens 104-117 20130363-0 2010 [Effect of RelB-silenced BMDC pulsed with Talpha146~162 on immunoreaction of T cells primed with TAChR]. bmdc 25-29 avian reticuloendotheliosis viral (v-rel) oncogene related B Mus musculus 11-15 20193348-13 2009 CONCLUSION: Mobilization of BMDC by G-CSF showed a protective effect on lung injury induced by bleomycin in mice, but did not have significant influence on survival time. bmdc 28-32 colony stimulating factor 3 (granulocyte) Mus musculus 36-41 19968878-7 2009 When iGb3 was incubated with BMDC and tested with DN32D3 cells, IL-2 was equally produced indicating iNKT cell activation. bmdc 29-33 alpha 1,3-galactosyltransferase 2 (isoglobotriaosylceramide synthase) Mus musculus 5-9 19968878-7 2009 When iGb3 was incubated with BMDC and tested with DN32D3 cells, IL-2 was equally produced indicating iNKT cell activation. bmdc 29-33 interleukin 2 Mus musculus 64-68 19759906-4 2009 Here, we demonstrate by bone marrow transplantation/reconstitution and genetic lineage-tracing experiments that BMDC integrate into tumor-associated lymphatic vessels in the Rip1Tag2 mouse model of insulinoma and in the TRAMP-C1 prostate cancer transplantation model, and that the integrated BMDC originate from the myelomonocytic lineage. bmdc 112-116 tumor necrosis factor receptor superfamily, member 25 Mus musculus 220-225 19342636-5 2009 NECA-treated BMDC also expressed reduced levels of MHC class II and CD86 and were less effective at stimulating CD4(+) T cell proliferation and IL-2 production compared with BMDC exposed to vehicle control. bmdc 13-17 CD86 antigen Mus musculus 68-72 19477431-3 2009 Here, we demonstrate that both IL-8 and angiogenin contribute to the complementary pathways of angiogenesis and BMDC mobilization to increase tumor growth. bmdc 112-116 C-X-C motif chemokine ligand 8 Homo sapiens 31-35 19342636-5 2009 NECA-treated BMDC also expressed reduced levels of MHC class II and CD86 and were less effective at stimulating CD4(+) T cell proliferation and IL-2 production compared with BMDC exposed to vehicle control. bmdc 13-17 interleukin 2 Mus musculus 144-148 18775800-9 2008 BMDC-stimulated IFN-gamma production from T-cells was significantly lower in NC/Nga or BALB/c mice than in C57BL/6J mice, whereas IL-4 production was significantly greater in NC/Nga and C57BL/6J mice than in BALB/c mice. bmdc 0-4 interferon gamma Mus musculus 16-25 18775800-10 2008 Taken together, GM-CSF-stimulated differentiation of BMDC was more accelerated in atopic prone NC/Nga mice than in the other strains of mice. bmdc 53-57 colony stimulating factor 2 (granulocyte-macrophage) Mus musculus 16-22 18515407-6 2008 Preincubation of BMDC with Diprotin A, a reversible inhibitor of CD26 peptidase activity that enhances the stromal-derived factor-1 (SDF-1/CXCL12)/CXCR4 axis, resulted in a 30% increase in the percentage of CMFDA(+) cells retained in the lung. bmdc 17-21 dipeptidylpeptidase 4 Mus musculus 65-69 18991288-7 2008 FGL2 inhibited the maturation of BMDC from FcgammaRIIB+/+ mice but not from FcgammaRIIB(-/-) mice and induced apoptosis in the FcgammaRIIB+ mouse B-cell line (A20) but not the A20IIA1.6 cell line that does not express FcgammaRIIB. bmdc 33-37 fibrinogen-like protein 2 Mus musculus 0-4 18991288-7 2008 FGL2 inhibited the maturation of BMDC from FcgammaRIIB+/+ mice but not from FcgammaRIIB(-/-) mice and induced apoptosis in the FcgammaRIIB+ mouse B-cell line (A20) but not the A20IIA1.6 cell line that does not express FcgammaRIIB. bmdc 33-37 Fc receptor, IgG, low affinity IIb Mus musculus 43-54 18515407-6 2008 Preincubation of BMDC with Diprotin A, a reversible inhibitor of CD26 peptidase activity that enhances the stromal-derived factor-1 (SDF-1/CXCL12)/CXCR4 axis, resulted in a 30% increase in the percentage of CMFDA(+) cells retained in the lung. bmdc 17-21 chemokine (C-X-C motif) ligand 12 Mus musculus 133-138 18515407-6 2008 Preincubation of BMDC with Diprotin A, a reversible inhibitor of CD26 peptidase activity that enhances the stromal-derived factor-1 (SDF-1/CXCL12)/CXCR4 axis, resulted in a 30% increase in the percentage of CMFDA(+) cells retained in the lung. bmdc 17-21 chemokine (C-X-C motif) ligand 12 Mus musculus 139-145 18515407-6 2008 Preincubation of BMDC with Diprotin A, a reversible inhibitor of CD26 peptidase activity that enhances the stromal-derived factor-1 (SDF-1/CXCL12)/CXCR4 axis, resulted in a 30% increase in the percentage of CMFDA(+) cells retained in the lung. bmdc 17-21 chemokine (C-X-C motif) receptor 4 Mus musculus 147-152 18250429-5 2008 When infected with Chlamydia, BMDC secrete increased TNF-alpha, IL-6, IL-10, IL-12, and IL-13. bmdc 30-34 interleukin 10 Mus musculus 70-75 18375954-4 2008 We report higher IL-23p19 mRNA accumulation and protein secretion in LPS-stimulated BMDC isolated from IL-10(-/-) compared with WT mice. bmdc 84-88 interleukin 23, alpha subunit p19 Mus musculus 17-25 18375954-4 2008 We report higher IL-23p19 mRNA accumulation and protein secretion in LPS-stimulated BMDC isolated from IL-10(-/-) compared with WT mice. bmdc 84-88 interleukin 10 Mus musculus 103-108 18250429-5 2008 When infected with Chlamydia, BMDC secrete increased TNF-alpha, IL-6, IL-10, IL-12, and IL-13. bmdc 30-34 interleukin 13 Mus musculus 88-93 18250429-6 2008 OVA peptide-pulsed infected BMDC induced significant proliferation of transgenic CD4(+) DO11.10 (D10) T cells, strongly inhibited IFN-gamma secretion by D10 cells, and promoted a Th2 phenotype. bmdc 28-32 interferon gamma Mus musculus 130-139 17467810-7 2007 In addition, pre-exposure of BMDC to Tk produced increased levels of IL-10, but decreased levels of IL-12, following subsequent lipopolysaccharide (LPS) stimulation. bmdc 29-33 interleukin 10 Mus musculus 69-74 18179826-5 2008 In the enzyme assay using cellular extracts of BMDC, the IDO activity of BMDC stimulated with CpG was enhanced by the addition of a NO synthase (NOS) inhibitor, suggesting that IDO activity was suppressed by NO production. bmdc 47-51 indoleamine 2,3-dioxygenase 1 Mus musculus 57-60 18179826-5 2008 In the enzyme assay using cellular extracts of BMDC, the IDO activity of BMDC stimulated with CpG was enhanced by the addition of a NO synthase (NOS) inhibitor, suggesting that IDO activity was suppressed by NO production. bmdc 47-51 nitric oxide synthase 1, neuronal Mus musculus 132-143 18179826-5 2008 In the enzyme assay using cellular extracts of BMDC, the IDO activity of BMDC stimulated with CpG was enhanced by the addition of a NO synthase (NOS) inhibitor, suggesting that IDO activity was suppressed by NO production. bmdc 47-51 indoleamine 2,3-dioxygenase 1 Mus musculus 177-180 18179826-5 2008 In the enzyme assay using cellular extracts of BMDC, the IDO activity of BMDC stimulated with CpG was enhanced by the addition of a NO synthase (NOS) inhibitor, suggesting that IDO activity was suppressed by NO production. bmdc 73-77 indoleamine 2,3-dioxygenase 1 Mus musculus 57-60 18179826-5 2008 In the enzyme assay using cellular extracts of BMDC, the IDO activity of BMDC stimulated with CpG was enhanced by the addition of a NO synthase (NOS) inhibitor, suggesting that IDO activity was suppressed by NO production. bmdc 73-77 nitric oxide synthase 1, neuronal Mus musculus 132-143 18179826-5 2008 In the enzyme assay using cellular extracts of BMDC, the IDO activity of BMDC stimulated with CpG was enhanced by the addition of a NO synthase (NOS) inhibitor, suggesting that IDO activity was suppressed by NO production. bmdc 73-77 indoleamine 2,3-dioxygenase 1 Mus musculus 177-180 18075238-4 2007 This study examined whether G-CSF and/or resveratrol affect the recruitment of BMDC into vascular endothelial cells and renal tubular cells and the kidney function after I/R injury. bmdc 79-83 colony stimulating factor 3 (granulocyte) Mus musculus 28-33 17615582-8 2007 When an hsp110-rat neu (intracellular domain) heat shock complex vaccine is used to pulse mouse bmDC in vitro, an induction of IFN-gamma secretion is observed by CD8+ T lymphocytes isolated from vaccine-immunized mice. bmdc 96-100 heat shock protein family A (Hsp70) member 4 Rattus norvegicus 8-14 17615582-8 2007 When an hsp110-rat neu (intracellular domain) heat shock complex vaccine is used to pulse mouse bmDC in vitro, an induction of IFN-gamma secretion is observed by CD8+ T lymphocytes isolated from vaccine-immunized mice. bmdc 96-100 interferon gamma Mus musculus 127-136 17521735-3 2007 In this study, we modified a BMDC vaccine by incorporating the SLC mature peptide gene. bmdc 29-33 chemokine (C-C motif) ligand 21A (serine) Mus musculus 63-66 18032545-6 2008 When anti-HGF IgG was injected in the earlier stage, tubular cell proliferation was inhibited, leading to an increase in BMDC in renal tubules. bmdc 121-125 hepatocyte growth factor Mus musculus 10-13 18032545-9 2008 Thus possible cascades include 1) inhibition of tubular cell proliferation by neutralizing HGF leads to renal hypoxia and SDF1 upregulation; and 2) BMDC are eventually engrafted in tubules through SDF1-mediated chemotaxis. bmdc 148-152 hepatocyte growth factor Mus musculus 91-94 18032545-9 2008 Thus possible cascades include 1) inhibition of tubular cell proliferation by neutralizing HGF leads to renal hypoxia and SDF1 upregulation; and 2) BMDC are eventually engrafted in tubules through SDF1-mediated chemotaxis. bmdc 148-152 chemokine (C-X-C motif) ligand 12 Mus musculus 197-201 18032545-10 2008 Inversely, administration of recombinant HGF suppressed the renal hypoxia, SDF1 upregulation, and BMDC engraftment in ARF mice by enhancing resident tubular cell proliferation. bmdc 98-102 hepatocyte growth factor Mus musculus 41-44 16339999-6 2006 Co-culture of BMDC with immune complexes of OVA and IgG anti-OVA together with OVA-sensitized spleen mononuclear cells resulted in increases in IL-13 production. bmdc 14-18 interleukin 13 Mus musculus 144-149 17378899-8 2007 Monoclonal antibodies that block IL-23 showed further that BMDC-derived IL-23 was required for production of IL-17 in this experimental model. bmdc 59-63 interleukin 23, alpha subunit p19 Mus musculus 33-38 17378899-8 2007 Monoclonal antibodies that block IL-23 showed further that BMDC-derived IL-23 was required for production of IL-17 in this experimental model. bmdc 59-63 interleukin 23, alpha subunit p19 Mus musculus 72-77 17202330-5 2007 The PGI(2) analogs decreased BMDC production of proinflammatory cytokines (IL-12, TNF-alpha, IL-1alpha, IL-6) and chemokines (MIP-1alpha, MCP-1) and increased the production of the anti-inflammatory cytokine IL-10 by BMDCs. bmdc 29-33 tumor necrosis factor Mus musculus 82-91 17202330-5 2007 The PGI(2) analogs decreased BMDC production of proinflammatory cytokines (IL-12, TNF-alpha, IL-1alpha, IL-6) and chemokines (MIP-1alpha, MCP-1) and increased the production of the anti-inflammatory cytokine IL-10 by BMDCs. bmdc 29-33 interleukin 1 alpha Mus musculus 93-102 17202330-5 2007 The PGI(2) analogs decreased BMDC production of proinflammatory cytokines (IL-12, TNF-alpha, IL-1alpha, IL-6) and chemokines (MIP-1alpha, MCP-1) and increased the production of the anti-inflammatory cytokine IL-10 by BMDCs. bmdc 29-33 interleukin 6 Mus musculus 104-108 17202330-5 2007 The PGI(2) analogs decreased BMDC production of proinflammatory cytokines (IL-12, TNF-alpha, IL-1alpha, IL-6) and chemokines (MIP-1alpha, MCP-1) and increased the production of the anti-inflammatory cytokine IL-10 by BMDCs. bmdc 29-33 mast cell protease 1 Mus musculus 138-143 17202330-5 2007 The PGI(2) analogs decreased BMDC production of proinflammatory cytokines (IL-12, TNF-alpha, IL-1alpha, IL-6) and chemokines (MIP-1alpha, MCP-1) and increased the production of the anti-inflammatory cytokine IL-10 by BMDCs. bmdc 29-33 interleukin 10 Mus musculus 208-213 15650175-10 2005 Candidate effectors of alternative antiviral pathways were those genes induced by virus infection or IFN-alpha/beta treatment in 129 Sv/Ev and TD-derived BMDC but not in virus-infected or IFN-alpha/beta-treated IFNAR1-/- cells. bmdc 154-158 interferon alpha Mus musculus 101-110 16508978-5 2006 BMDC activation was determined by flow cytometry (CD40, CD86). bmdc 0-4 CD40 molecule Homo sapiens 50-54 16508978-5 2006 BMDC activation was determined by flow cytometry (CD40, CD86). bmdc 0-4 CD86 molecule Homo sapiens 56-60 15546160-3 2005 This study establishes that bone marrow-derived epidermal cells are proliferative and, moreover, demonstrates for the first time that BMDC can localize to a known stem cell niche: the CD34-positive bulge region of mouse hair follicles. bmdc 134-138 CD34 antigen Mus musculus 184-188 15187118-7 2004 Although WT bone marrow cultures died within 4 wk, IL-6(-/-) cultures continued to generate BMDC for >120 days, although the BMDC became immature and less functional. bmdc 92-96 interleukin 6 Mus musculus 51-55 15533866-6 2004 Administration of AMD3100, which specifically blocks binding of SDF-1 to its endogenous receptor CXCR4, diminished BMDC recruitment after MI by 64.2+/-5.5% (P<0.05), strongly suggesting a requirement for SDF-1 in BMDC recruitment to the infarcted heart. bmdc 115-119 C-X-C motif chemokine ligand 12 Homo sapiens 64-69 15919369-8 2004 We found that the BMDC from DBA/2 mice showed significant upregulation of Toll-like receptor-2 and 4 genes expression, secretion of IL-12 (p<0.05) and modest increase in T cell co-stimulatory molecules as compared to BMDC from BALB/c mice. bmdc 18-22 toll-like receptor 2 Mus musculus 74-100 15128817-3 2004 In contrast, all mice vaccinated with a single dose of Leishmania major Ag-pulsed BMDC stimulated by prior in vitro exposure to CpG-containing oligodeoxynucleotides (ODN) were completely protected, had a dramatic reduction in parasite burden, and developed an Ag-specific Th1 response. bmdc 82-86 negative elongation factor complex member C/D, Th1l Mus musculus 272-275 11369698-8 2001 Antigen uptake and processing of HA-IL-2 by BMDC was required since fixing BMDC, prior to antigen exposure, greatly reduced their ability to activate A5 cells. bmdc 44-48 interleukin 2 Mus musculus 36-40 12429720-6 2002 The presence of IL-4 enhanced the yield and maturation of BMDC but inhibited LPS-induced IL-10 production by eDC. bmdc 58-62 interleukin 4 Homo sapiens 16-20 14597102-7 2003 Finally, preincubation of BMDC with LPS in presence of the specific beta2-AR agonist salbutamol impaired their chemotactic response to CCL19 and CCL21 and this effect was neutralized by anti-IL-10 mAb. bmdc 26-30 adrenergic receptor, beta 2 Mus musculus 68-76 14597102-7 2003 Finally, preincubation of BMDC with LPS in presence of the specific beta2-AR agonist salbutamol impaired their chemotactic response to CCL19 and CCL21 and this effect was neutralized by anti-IL-10 mAb. bmdc 26-30 chemokine (C-C motif) ligand 19 Mus musculus 135-140 14597102-7 2003 Finally, preincubation of BMDC with LPS in presence of the specific beta2-AR agonist salbutamol impaired their chemotactic response to CCL19 and CCL21 and this effect was neutralized by anti-IL-10 mAb. bmdc 26-30 interleukin 10 Mus musculus 191-196 12460194-5 2002 We demonstrate that IL-10 can prevent BMDC maturation, as measured by both cytokine production and T-cell priming capacity in vitro. bmdc 38-42 interleukin 10 Mus musculus 20-25 12356687-5 2002 In response to lipopolysaccharide (LPS), IFN-beta gene expression was augmented in both wild-type and MyD88-deficient BMDC. bmdc 118-122 interferon beta 1 Homo sapiens 41-49 12356687-5 2002 In response to lipopolysaccharide (LPS), IFN-beta gene expression was augmented in both wild-type and MyD88-deficient BMDC. bmdc 118-122 MYD88 innate immune signal transduction adaptor Homo sapiens 102-107 11792384-5 2002 Furthermore, F-18-labeled BMDC stimulated allogeneic T cells in a mixed leukocyte reaction as potently as did sham-treated BMDC and migrated towards secondary lymphoid tissue chemokine (SLC) in a chemotaxis assay in vitro with the same efficiency as sham-treated BMDC. bmdc 26-30 chemokine (C-C motif) ligand 21A (serine) Mus musculus 149-184 11792384-5 2002 Furthermore, F-18-labeled BMDC stimulated allogeneic T cells in a mixed leukocyte reaction as potently as did sham-treated BMDC and migrated towards secondary lymphoid tissue chemokine (SLC) in a chemotaxis assay in vitro with the same efficiency as sham-treated BMDC. bmdc 26-30 chemokine (C-C motif) ligand 21A (serine) Mus musculus 186-189 11369698-8 2001 Antigen uptake and processing of HA-IL-2 by BMDC was required since fixing BMDC, prior to antigen exposure, greatly reduced their ability to activate A5 cells. bmdc 75-79 interleukin 2 Mus musculus 36-40 9886383-8 1999 In correspondence to their maturation stage, BmDC cultured in the presence of CD40L exhibited the most potent immunostimulatory effects. bmdc 45-49 CD40 ligand Mus musculus 78-83 10918477-6 2000 Consistent with DC activation, FACs analysis showed BMDC infected with Ad vectors up-regulated the surface expression of B7-2, ICAM-1 and MHC II. bmdc 52-56 CD86 antigen Mus musculus 121-125 10918477-6 2000 Consistent with DC activation, FACs analysis showed BMDC infected with Ad vectors up-regulated the surface expression of B7-2, ICAM-1 and MHC II. bmdc 52-56 intercellular adhesion molecule 1 Mus musculus 127-133 10918477-6 2000 Consistent with DC activation, FACs analysis showed BMDC infected with Ad vectors up-regulated the surface expression of B7-2, ICAM-1 and MHC II. bmdc 52-56 histocompatibility-2, MHC Mus musculus 138-144 10925779-8 2000 It has been found that local pretreatment with BMDC inhibits growth of a subsequent challenge inoculum of the MK16 cells. bmdc 47-51 potassium voltage-gated channel, shaker-related, subfamily, member 6 Mus musculus 110-114 9286353-7 1997 Incubation of bone marrow-derived DC with IL-4 (100 U/ml) resulted in downregulation of CD14 surface expression, whereas exposure of BmDC to LPS (1 microgram/ml) led to upregulation of CD14. bmdc 133-137 CD14 antigen Mus musculus 185-189 9022030-6 1997 We show that BMDC presented exogenous ovalbumin to a T cell hybridoma more effectively, more rapidly, and at lower exogenous antigen concentrations than BM macrophages on a cell-for-cell basis. bmdc 13-17 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 38-47 9022030-9 1997 Finally, PMA-stimulated BMDC exposed to exogenous ovalbumin in vitro were able to prime an antigen-specific cytotoxic T lymphocyte response following adoptive transfer in vivo. bmdc 24-28 serine (or cysteine) peptidase inhibitor, clade B, member 1, pseudogene Mus musculus 50-59 32807859-5 2020 SOCS3-/- DCs slightly attenuated BMDC-induced immunogenic tolerance. bmdc 33-37 suppressor of cytokine signaling 3 Mus musculus 0-5